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Prostaglandins and adenosine in the regulation of sleep and wakefulness. |
2007 |
Curr Opin Pharmacol |
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Upregulation of MIP-2 (CXCL2) expression by 15-deoxy-Delta(12,14)-prostaglandin J(2) in mouse peritoneal macrophages. |
2007 |
Immunol. Cell Biol. |
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Hepatic ischemia-reperfusion induces renal heme oxygenase-1 via NF-E2-related factor 2 in rats and mice. |
2007 |
Mol. Pharmacol. |
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Expression and potential role of peroxisome proliferator-activated receptor gamma in the placenta of diabetic pregnancy. |
2007 |
Placenta |
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Quantitative analysis of eosinophil chemotaxis tracked using a novel optical device -- TAXIScan. |
2007 |
J. Immunol. Methods |
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Cyclooxygenase-independent inhibition of H2O2-induced cell death by S-ketoprofen in renal cells. |
2007 |
Pharmacol. Res. |
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Identification of actin as a 15-deoxy-Delta12,14-prostaglandin J2 target in neuroblastoma cells: mass spectrometric, computational, and functional approaches to investigate the effect on cytoskeletal derangement. |
2007 |
Biochemistry |
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Pettipher R et al. |
Antagonism of the prostaglandin D2 receptors DP1 and CRTH2 as an approach to treat allergic diseases. |
2007 |
Nat Rev Drug Discov |
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Modification of proteins by cyclopentenone prostaglandins is differentially modulated by GSH in vitro. |
2007 |
Ann. N. Y. Acad. Sci. |
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Targeting 15d-prostaglandin J2 to hepatic stellate cells: two options evaluated. |
2007 |
Pharm. Res. |
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Putative mechanism of the itch-scratch circle: repeated scratching decreases the cutaneous level of prostaglandin D2, a mediator that inhibits itching. |
2007 |
Prostaglandins Leukot. Essent. Fatty Acids |
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THE PPARgamma ligand 15d-PGJ2 modulates macrophage activation after injury in a murine trauma model. |
2007 |
Shock |
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Diverse cardioprotective signaling mechanisms of peroxisome proliferator-activated receptor-gamma ligands, 15-deoxy-Delta12,14-prostaglandin J2 and ciglitazone, in reperfusion injury: role of nuclear factor-kappaB, heat shock factor 1, and Akt. |
2007 |
Shock |
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The anti-inflammatory effects of selenium are mediated through 15-deoxy-Delta12,14-prostaglandin J2 in macrophages. |
2007 |
J. Biol. Chem. |
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Prostaglandin D2 protects neonatal mouse brain from hypoxic ischemic injury. |
2007 |
J. Neurosci. |
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Sensitization and activation of intracranial meningeal nociceptors by mast cell mediators. |
2007 |
J. Pharmacol. Exp. Ther. |
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The role of PPARgamma on restoration of colonic homeostasis after experimental stress-induced inflammation and dysfunction. |
2007 |
Gastroenterology |
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15-Deoxy-Delta12,14-prostaglandin J2 enhances docetaxel anti-tumor activity against A549 and H460 non-small-cell lung cancer cell lines and xenograft tumors. |
2007 |
Anticancer Drugs |
pmid:17159504
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Involvement of PPARgamma in human trophoblast invasion. |
2007 |
Placenta |
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Hematopoietic prostaglandin D2 synthase controls the onset and resolution of acute inflammation through PGD2 and 15-deoxyDelta12 14 PGJ2. |
2007 |
Proc. Natl. Acad. Sci. U.S.A. |
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Interleukin (IL)-33 induces the release of pro-inflammatory mediators by mast cells. |
2007 |
Cytokine |
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2007 |
J. Immunol. |
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[15-deoxy-Delta(12,14)-prostaglandin J(2) induces anoikis of hepatocellular carcinoma cells: an in vitro experiment]. |
2007 |
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15-deoxy-Delta(12,14)-prostaglandin J2 inhibits G2-M phase progression in human breast cancer cells via the down-regulation of cyclin B1 and survivin expression. |
2007 |
Breast Cancer Res. Treat. |
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Anti-inflammatory effects of PPAR-gamma agonists directly correlate with PPAR-gamma expression during acute pancreatitis. |
2006 Sep-Oct |
J. Gastrointest. Surg. |
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The thiazolidinedione drug troglitazone up-regulates nitric oxide synthase expression in vascular endothelial cells. |
2006 Sep-Oct |
J. Diabetes Complicat. |
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Rat basophilic leukemia cells (RBL-2H3) generate prostaglandin D2 (PGD2) after regulated upon activation, normal T-cell expressed and secreted (RANTES) activation. |
2006 Oct-Dec |
Int. J. Biol. Markers |
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15-Deoxy-Delta(12,14)-prostaglandin J(2) and troglitazone regulation of the release of phospholipid metabolites, inflammatory cytokines and proteases from human gestational tissues. |
2006 Nov-Dec |
Placenta |
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Urade Y |
Twenty-fifth anniversary of the discovery of somnogenic activity of prostaglandin D2: sleep research directed by Osamu Hayaishi. |
2006 May-Jun |
IUBMB Life |
pmid:16754308
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Presence and characterization of prostaglandin D2-related molecules in nasal mucosa of patients with allergic rhinitis. |
2006 May-Jun |
Am J Rhinol |
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Mast cell inhibitor R112 is well tolerated and affects prostaglandin D2 but not other mediators, symptoms, or nasal volumes in a nasal challenge model of allergic rhinitis. |
2006 May-Jun |
Allergy Asthma Proc |
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Kim SJ et al. |
Effects of methyl gallate on arachidonic acid metabolizing enzymes: Cyclooxygenase-2 and 5-lipoxygenase in mouse bone marrow-derived mast cells. |
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Arch. Pharm. Res. |
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Vanin-1 licenses inflammatory mediator production by gut epithelial cells and controls colitis by antagonizing peroxisome proliferator-activated receptor gamma activity. |
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15-deoxy-Delta12,14-prostaglandin J2 induces renal epithelial cell death through NF-kappaB-dependent and MAPK-independent mechanism. |
2006 |
Toxicol. Appl. Pharmacol. |
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15-Deoxy-Delta12,14-prostaglandin J(2) induces death receptor 5 expression through mRNA stabilization independently of PPARgamma and potentiates TRAIL-induced apoptosis. |
2006 |
Mol. Cancer Ther. |
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Wang XS and Lau HY |
Beta-adrenoceptor-mediated inhibition of mediator release from human peripheral blood-derived mast cells. |
2006 |
Clin. Exp. Pharmacol. Physiol. |
pmid:16895550
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Prostaglandin D2 inhibits TGF-beta1-induced epithelial-to-mesenchymal transition in MDCK cells. |
2006 |
Am. J. Physiol. Renal Physiol. |
pmid:16896186
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PPARgamma-independent induction of growth arrest and apoptosis in prostate and bladder carcinoma. |
2006 |
BMC Cancer |
pmid:16519808
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The 2-series prostaglandins suppress VLDL secretion in an inflammatory condition-dependent manner in primary rat hepatocytes. |
2006 |
Biochim. Biophys. Acta |
pmid:16545597
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Lack of interaction between prostaglandin E2 receptor subtypes in regulating adenylyl cyclase activity in cultured rat dorsal root ganglion cells. |
2006 |
Eur. J. Pharmacol. |
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Functional characterization of human mast cells cultured from adult peripheral blood. |
2006 |
Int. Immunopharmacol. |
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Activation of peroxisome proliferator-activated receptor-gamma decreases pancreatic cancer cell invasion through modulation of the plasminogen activator system. |
2006 |
Mol. Cancer Res. |
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Inhibition of gastric cancer cells associated angiogenesis by 15d-prostaglandin J2 through the downregulation of angiopoietin-1. |
2006 |
Cancer Lett. |
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15-Deoxy-Delta(12,14)-prostaglandin J(2) suppresses IL-6-induced STAT3 phosphorylation via electrophilic reactivity in endothelial cells. |
2006 |
Life Sci. |
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On the mechanism of interaction of potent surmountable and insurmountable antagonists with the prostaglandin D2 receptor CRTH2. |
2006 |
Mol. Pharmacol. |
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High levels of filamentous actin and apoptosis correlate with mast cell refractoriness under alloxan-evoked diabetes. |
2006 |
Life Sci. |
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Effects of 15d-PGJ(2) on VEGF-induced angiogenic activities and expression of VEGF receptors in endothelial cells. |
2006 |
Prostaglandins Other Lipid Mediat. |
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Anti-inflammatory activity of Ailanthus altissima in ovalbumin-induced lung inflammation. |
2006 |
Biol. Pharm. Bull. |
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Prostaglandin D2-mediated microglia/astrocyte interaction enhances astrogliosis and demyelination in twitcher. |
2006 |
J. Neurosci. |
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Effects of 15-deoxy-Delta12,14-prostaglandin-J2 during hyperdynamic porcine endotoxemia. |
2006 |
Intensive Care Med |
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A role of PPAR-gamma in androstenediol-mediated salutary effects on cardiac function following trauma-hemorrhage. |
2006 |
Ann. Surg. |
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Effects of PPARgamma agonists on cell survival and focal adhesions in a Chinese thyroid carcinoma cell line. |
2006 |
J. Cell. Biochem. |
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Signal pathways involved in the regulation of prostaglandin E synthase-1 in human gingival fibroblasts. |
2006 |
Cell. Signal. |
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Peroxisome proliferator-activated receptor-gamma1 is dephosphorylated and degraded during BAY 11-7085-induced synovial fibroblast apoptosis. |
2006 |
J. Biol. Chem. |
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Sugimoto M et al. |
Role of COX-1 and COX-2 on skin PGs biosynthesis by mechanical scratching in mice. |
2006 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:16815697
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Determination of a prostaglandin D2 antagonist and its acyl glucuronide metabolite in human plasma by high performance liquid chromatography with tandem mass spectrometric detection--a lack of MS/MS selectivity between a glucuronide conjugate and a phase I metabolite. |
2006 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:16716772
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Na HK and Surh YJ |
Transcriptional regulation via cysteine thiol modification: a novel molecular strategy for chemoprevention and cytoprotection. |
2006 |
Mol. Carcinog. |
pmid:16673384
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BrazÃs P et al. |
Dermal microdialysis in the dog: in vivo assessment of the effect of cyclosporin A on cutaneous histamine and prostaglandin D2 release. |
2006 |
Vet. Dermatol. |
pmid:16674731
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Hickson-Bick DL et al. |
The response of neonatal rat ventricular myocytes to lipopolysaccharide-induced stress. |
2006 |
Shock |
pmid:16680021
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Son MJ et al. |
Naturally occurring biflavonoid, ochnaflavone, inhibits cyclooxygenases-2 and 5-lipoxygenase in mouse bone marrow-derived mast cells. |
2006 |
Arch. Pharm. Res. |
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[Effects of peroxisome proliferators-activated receptor gamma agonists on transforming growth factor-beta1 and Smads signal pathway: experiment with rat renal fibroblasts]. |
2006 |
Zhonghua Yi Xue Za Zhi |
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PPAR gamma inhibits growth of rat hepatic stellate cells and TGF beta-induced connective tissue growth factor expression. |
2006 |
Acta Pharmacol. Sin. |
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Neuronal expression of peroxisome proliferator-activated receptor-gamma (PPARgamma) and 15d-prostaglandin J2--mediated protection of brain after experimental cerebral ischemia in rat. |
2006 |
Brain Res. |
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Rosiglitazone ameliorates cisplatin-induced renal injury in mice. |
2006 |
Nephrol. Dial. Transplant. |
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Rajasingh J and Bright JJ |
15-Deoxy-delta12,14-prostaglandin J2 regulates leukemia inhibitory factor signaling through JAK-STAT pathway in mouse embryonic stem cells. |
2006 |
Exp. Cell Res. |
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Prostaglandin J2 alters pro-survival and pro-death gene expression patterns and 26 S proteasome assembly in human neuroblastoma cells. |
2006 |
J. Biol. Chem. |
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Peroxisome proliferator-activated receptor gamma ligands stimulate myeloid differentiation and lipogenensis in human leukemia NB4 cells. |
2006 |
Dev. Growth Differ. |
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[The role of peroxisome proliferator-activated receptor gamma in proliferation of cardiac non myocytes]. |
2006 |
Zhongguo Ying Yong Sheng Li Xue Za Zhi |
pmid:21162229
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Garg TK and Chang JY |
Methylmercury causes oxidative stress and cytotoxicity in microglia: attenuation by 15-deoxy-delta 12, 14-prostaglandin J2. |
2006 |
J. Neuroimmunol. |
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Spectroscopic analyses of the binding kinetics of 15d-PGJ2 to the PPARgamma ligand-binding domain by multi-wavelength global fitting. |
2006 |
Biochem. J. |
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PPAR-gamma inhibits ANG II-induced cell growth via SHIP2 and 4E-BP1. |
2006 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:16155101
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Peroxisome proliferator-activated receptor-gamma is expressed by rat peritoneal mesothelial cells: its potential role in peritoneal cavity local defense. |
2006 |
Am. J. Nephrol. |
pmid:17183189
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[Stress and inflammatory bowell disease (I.B.D). Therapeutic strategies]. |
2006 |
An R Acad Nac Med (Madr) |
pmid:17172222
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Potentiation of tumor formation by topical administration of 15-deoxy-delta12,14-prostaglandin J2 in a model of skin carcinogenesis. |
2006 |
Carcinogenesis |
pmid:16113051
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PPAR-gamma ligands and amino acid deprivation promote apoptosis of melanoma, prostate, and breast cancer cells. |
2006 |
Cancer Lett. |
pmid:15979236
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15-Deoxy-12,14-prostaglandin J2 inhibits interferon gamma induced MHC class II but not class I expression on ARPE cells through a PPAR gamma independent mechanism. |
2006 |
Prostaglandins Other Lipid Mediat. |
pmid:16939878
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Lim HJ et al. |
PPARgamma activation induces CD36 expression and stimulates foam cell like changes in rVSMCs. |
2006 |
Prostaglandins Other Lipid Mediat. |
pmid:16939881
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Chiba T et al. |
Prostaglandin D2 induces IL-8 and GM-CSF by bronchial epithelial cells in a CRTH2-independent pathway. |
2006 |
Int. Arch. Allergy Immunol. |
pmid:16940740
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Nrf2-mediated induction of cytoprotective enzymes by 15-deoxy-Delta12,14-prostaglandin J2 is attenuated by alkenal/one oxidoreductase. |
2006 |
J. Biol. Chem. |
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Induction of adaptive response and enhancement of PC12 cell tolerance by 7-hydroxycholesterol and 15-deoxy-delta(12,14)-prostaglandin J2 through up-regulation of cellular glutathione via different mechanisms. |
2006 |
J. Biol. Chem. |
pmid:16565077
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Horiguchi T et al. |
Cyclooxygenase-2 mediates the development of cortical spreading depression-induced tolerance to transient focal cerebral ischemia in rats. |
2006 |
Neuroscience |
pmid:16567054
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Siddhivarn C et al. |
Prostaglandin D2 pathway and peroxisome proliferator-activated receptor gamma-1 expression are induced by mechanical loading in an osteoblastic cell line. |
2006 |
J. Periodont. Res. |
pmid:16499711
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Coyle AT and Kinsella BT |
Synthetic peroxisome proliferator-activated receptor gamma agonists rosiglitazone and troglitazone suppress transcription by promoter 3 of the human thromboxane A2 receptor gene in human erythroleukemia cells. |
2006 |
Biochem. Pharmacol. |
pmid:16499875
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Makino N et al. |
Peroxisome proliferator-activated receptor-gamma ligands attenuate brain natriuretic peptide production and affect remodeling in cardiac fibroblasts in reoxygenation after hypoxia. |
2006 |
Cell Biochem. Biophys. |
pmid:16456235
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Figarella K et al. |
Prostaglandin-induced programmed cell death in Trypanosoma brucei involves oxidative stress. |
2006 |
Cell Death Differ. |
pmid:16456581
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Peroxisome proliferator-activated receptor gamma agonists as therapy for chronic airway inflammation. |
2006 |
Eur. J. Pharmacol. |
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Prostanoids as pharmacological targets in COPD and asthma. |
2006 |
Eur. J. Pharmacol. |
pmid:16458293
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15-deoxy-Delta12,14-prostaglandin J2 attenuates development of cyclophosphamide-induced cystitis in rats. |
2006 |
Urology |
pmid:16461118
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Anti-asthmatic activity of an ethanol extract from Saururus chinensis. |
2006 |
Biol. Pharm. Bull. |
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Raetz CR et al. |
Kdo2-Lipid A of Escherichia coli, a defined endotoxin that activates macrophages via TLR-4. |
2006 |
J. Lipid Res. |
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The in vitro real-time oscillation monitoring system identifies potential entrainment factors for circadian clocks. |
2006 |
BMC Mol. Biol. |
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Quantitative characterization of 15-deoxy-delta(12,14)-prostaglandin J2 in regulating EGFPSmad2 translocation in CHO cells through PPARgamma/TGFbeta/Smad2 pathway. |
2006 |
Cell. Physiol. Biochem. |
pmid:16914899
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Lee JJ et al. |
Antiplatelet activity of carnosol is mediated by the inhibition of TXA2 receptor and cytosolic calcium mobilization. |
2006 |
Vascul. Pharmacol. |
pmid:16916624
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Ulven T and Kostenis E |
Targeting the prostaglandin D2 receptors DP and CRTH2 for treatment of inflammation. |
2006 |
Curr Top Med Chem |
pmid:16918458
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Theiner G et al. |
The mast cell mediator PGD2 suppresses IL-12 release by dendritic cells leading to Th2 polarized immune responses in vivo. |
2006 |
Immunobiology |
pmid:16920486
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Urade Y and Mohri I |
[Sleep and brain function]. |
2006 |
No To Hattatsu |
pmid:16986732
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Kim EH and Surh YJ |
15-deoxy-Delta12,14-prostaglandin J2 as a potential endogenous regulator of redox-sensitive transcription factors. |
2006 |
Biochem. Pharmacol. |
pmid:16987499
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Diaz BL et al. |
Group V secretory phospholipase A2 amplifies the induction of cyclooxygenase 2 and delayed prostaglandin D2 generation in mouse bone marrow culture-derived mast cells in a strain-dependent manner. |
2006 |
Biochim. Biophys. Acta |
pmid:17064958
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Qin S et al. |
Protection of RPE cells from oxidative injury by 15-deoxy-delta12,14-prostaglandin J2 by augmenting GSH and activating MAPK. |
2006 |
Invest. Ophthalmol. Vis. Sci. |
pmid:17065531
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Gyles SL et al. |
A dominant role for chemoattractant receptor-homologous molecule expressed on T helper type 2 (Th2) cells (CRTH2) in mediating chemotaxis of CRTH2+ CD4+ Th2 lymphocytes in response to mast cell supernatants. |
2006 |
Immunology |
pmid:17067313
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