Yang G et al. |
Systemic PPARγ deletion impairs circadian rhythms of behavior and metabolism. |
2012 |
PLoS ONE |
pmid:22899986
|
Nicholson JD et al. |
PGJ(2) provides prolonged CNS stroke protection by reducing white matter edema. |
2012 |
PLoS ONE |
pmid:23284631
|
Wang Y et al. |
Optimization of phenylacetic acid derivatives for CRTH2 and DP selective antagonism. |
2012 |
Bioorg. Med. Chem. Lett. |
pmid:22119474
|
Alba G et al. |
Transcription of liver X receptor is down-regulated by 15-deoxy-Δ(12,14)-prostaglandin J(2) through oxidative stress in human neutrophils. |
2012 |
PLoS ONE |
pmid:23115616
|
Hossain MS et al. |
Stable expression of lipocalin-type prostaglandin D synthase in cultured preadipocytes impairs adipogenesis program independently of endogenous prostanoids. |
2012 |
Exp. Cell Res. |
pmid:22100987
|
Pettipher R et al. |
Pharmacologic profile of OC000459, a potent, selective, and orally active D prostanoid receptor 2 antagonist that inhibits mast cell-dependent activation of T helper 2 lymphocytes and eosinophils. |
2012 |
J. Pharmacol. Exp. Ther. |
pmid:22106101
|
Paulitschke V et al. |
Proteome analysis identified the PPARγ ligand 15d-PGJ2 as a novel drug inhibiting melanoma progression and interfering with tumor-stroma interaction. |
2012 |
PLoS ONE |
pmid:23049949
|
Bain G et al. |
Pharmacodynamics, pharmacokinetics, and safety of AM211: a novel and potent antagonist of the prostaglandin D2 receptor type 2. |
2012 |
J Clin Pharmacol |
pmid:22110163
|
Syeda PK et al. |
A monoclonal antibody specific for Δ12-prostaglandin J2 and its utilization in the immunological assay in cell culture system of adipocytes. |
2012 |
Hybridoma (Larchmt) |
pmid:23098304
|
Gates D et al. |
Apo J/clusterin expression and secretion: evidence for 15-deoxy-Δ(12,14)-PGJ(2)-dependent mechanism. |
2012 |
Biochim. Biophys. Acta |
pmid:22138303
|
Weng Y et al. |
Prostaglandin metabolite induces inhibition of TRPA1 and channel-dependent nociception. |
2012 |
Mol Pain |
pmid:23013719
|
Ravindra KC et al. |
Targeting of histone acetyltransferase p300 by cyclopentenone prostaglandin Δ(12)-PGJ(2) through covalent binding to Cys(1438). |
2012 |
Chem. Res. Toxicol. |
pmid:22141352
|
Maurer M and Church MK |
Inflammatory skin responses induced by icatibant injection are mast cell mediated and attenuated by H(1)-antihistamines. |
2012 |
Exp. Dermatol. |
pmid:22142018
|
Fujimori K et al. |
Prevention of paraquat-induced apoptosis in human neuronal SH-SY5Y cells by lipocalin-type prostaglandin D synthase. |
2012 |
J. Neurochem. |
pmid:22043816
|
Sedej M et al. |
D-type prostanoid receptor enhances the signaling of chemoattractant receptor-homologous molecule expressed on T(H)2 cells. |
2012 |
J. Allergy Clin. Immunol. |
pmid:21930295
|
Higuchi S et al. |
Involvement of Th2 cytokines in the mouse model of flutamide-induced acute liver injury. |
2012 |
J Appl Toxicol |
pmid:21735453
|
Pasvanis S et al. |
High sodium butyrate levels induce MDR1 activation in colorectal cells: Impact of 15-deoxy-Δ(12,14)-prostaglandin J(2) on the resistance to saquinavir. |
2012 |
Biochem. Biophys. Res. Commun. |
pmid:22293191
|
Li X et al. |
Natural vanadium-containing Jeju groundwater inhibits immunoglobulin E-mediated anaphylactic reaction and suppresses eicosanoid generation and degranulation in bone marrow derived-mast cells. |
2012 |
Biol. Pharm. Bull. |
pmid:22293352
|
He S et al. |
Identification, organ expression and ligand-dependent expression levels of peroxisome proliferator activated receptors in grass carp (Ctenopharyngodon idella). |
2012 |
Comp. Biochem. Physiol. C Toxicol. Pharmacol. |
pmid:22079418
|
Clemente-Napimoga JT et al. |
15d-PGJ2-loaded in nanocapsules enhance the antinociceptive properties into rat temporomandibular hypernociception. |
2012 |
Life Sci. |
pmid:22564409
|
Inceoglu AB et al. |
Inhibition of soluble epoxide hydrolase limits niacin-induced vasodilation in mice. |
2012 |
J. Cardiovasc. Pharmacol. |
pmid:22526297
|
Higashi N et al. |
Aspirin-intolerant asthma (AIA) assessment using the urinary biomarkers, leukotriene E4 (LTE4) and prostaglandin D2 (PGD2) metabolites. |
2012 |
Allergol Int |
pmid:22627848
|
Kristensen DM et al. |
Paracetamol (acetaminophen), aspirin (acetylsalicylic acid) and indomethacin are anti-androgenic in the rat foetal testis. |
2012 |
Int. J. Androl. |
pmid:22612476
|
Hogrefe C et al. |
Single impact cartilage trauma and TNF-α: interactive effects do not increase early cell death and indicate the need for bi-/multidirectional therapeutic approaches. |
2012 |
Int. J. Mol. Med. |
pmid:22922824
|
Lee E et al. |
15-Deoxy-Δ12,14-prostaglandin J₂ modulates manganese-induced activation of the NF-κB, Nrf2, and PI3K pathways in astrocytes. |
2012 |
Free Radic. Biol. Med. |
pmid:22245093
|
Lee S et al. |
Lipocalin-type prostaglandin D2 synthase protein regulates glial cell migration and morphology through myristoylated alanine-rich C-kinase substrate: prostaglandin D2-independent effects. |
2012 |
J. Biol. Chem. |
pmid:22275363
|
Ledwidge MT et al. |
In vivo impact of prodrug isosorbide-5-nicotinate-2-aspirinate on lipids and prostaglandin D2: is this a new immediate-release therapeutic option for niacin? |
2012 |
Atherosclerosis |
pmid:22326030
|
Baek K et al. |
Myeloid Elf-1-like factor stimulates adipogenic differentiation through the induction of peroxisome proliferator-activated receptor γ expression in bone marrow. |
2012 |
J. Cell. Physiol. |
pmid:22307523
|
Mantel A et al. |
Aldo-keto reductase 1C3 is expressed in differentiated human epidermis, affects keratinocyte differentiation, and is upregulated in atopic dermatitis. |
2012 |
J. Invest. Dermatol. |
pmid:22170488
|
Farnesi-de-Assunção TS et al. |
PPAR-γ agonists, mainly 15d-PGJ(2), reduce eosinophil recruitment following allergen challenge. |
2012 |
Cell. Immunol. |
pmid:22192475
|
Kuriyan AE et al. |
Electrophilic PPARγ ligands inhibit corneal fibroblast to myofibroblast differentiation in vitro: a potentially novel therapy for corneal scarring. |
2012 |
Exp. Eye Res. |
pmid:22178289
|
Yang K et al. |
[Changes of prostaglandin D2,carboxypeptidase A3 and platelet activating factor in guinea pig in anaphylactic shock]. |
2012 |
Fa Yi Xue Za Zhi |
pmid:22812216
|
Komoda T and Nishikawa M |
6'-Hydroxyoxosorbicillinol, a new lipoxygenase inhibitor and PGD2/LTB4 release suppressor from Penicillium sp. |
2012 |
Biosci. Biotechnol. Biochem. |
pmid:22785490
|
Joo M and Sadikot RT |
PGD synthase and PGD2 in immune resposne. |
2012 |
Mediators Inflamm. |
pmid:22791937
|
Baudouin-Legros M et al. |
Long-term CFTR inhibition modulates 15d-prostaglandin J2 in human pulmonary cells. |
2012 |
Int. J. Biochem. Cell Biol. |
pmid:22481026
|
Weng Z et al. |
Quercetin is more effective than cromolyn in blocking human mast cell cytokine release and inhibits contact dermatitis and photosensitivity in humans. |
2012 |
PLoS ONE |
pmid:22470478
|
Takahashi G et al. |
The potential role of prostaglandin D2 in nasal congestion observed in a guinea pig model of allergic rhinitis. |
2012 |
Int. Arch. Allergy Immunol. |
pmid:22472859
|
Abdo H et al. |
The omega-6 fatty acid derivative 15-deoxy-Δ¹²,¹â´-prostaglandin J2 is involved in neuroprotection by enteric glial cells against oxidative stress. |
2012 |
J. Physiol. (Lond.) |
pmid:22473776
|
Ji Y et al. |
Activation of rat intestinal mucosal mast cells by fat absorption. |
2012 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:22461027
|
Liu X et al. |
15-Deoxy-Δ(12,14)-prostaglandin J(2) attenuates the biological activities of monocyte/macrophage cell lines. |
2012 |
Eur. J. Cell Biol. |
pmid:22560326
|
Gross-Sondej I et al. |
[Measurement of bronchoconstrictive eicosanoids in chronic obstructive pulmonary disease]. |
2012 |
Pneumonol Alergol Pol |
pmid:22370980
|
Han Z et al. |
15-deoxy-Δ12,14 -prostaglandin J2 reduces recruitment of bone marrow-derived monocyte/macrophages in chronic liver injury in mice. |
2012 |
Hepatology |
pmid:22371273
|
Syeda PK et al. |
Generation of monoclonal antibody for 15-deoxy-Δ¹²,¹â´-prostaglandin Jâ‚‚ and development of enzyme-linked immunosorbent assay for its quantification in culture medium of adipocytes. |
2012 |
Appl. Biochem. Biotechnol. |
pmid:22391692
|
Quinteiro MS et al. |
The indirect antinociceptive mechanism of 15d-PGJ2 on rheumatoid arthritis-induced TMJ inflammatory pain in rats. |
2012 |
Eur J Pain |
pmid:22354681
|
Prage EB et al. |
Observation of two modes of inhibition of human microsomal prostaglandin E synthase 1 by the cyclopentenone 15-deoxy-Δ(12,14)-prostaglandin J(2). |
2012 |
Biochemistry |
pmid:22356188
|
Numazawa S et al. |
Possible involvement of transient receptor potential channels in electrophile-induced insulin secretion from RINm5F cells. |
2012 |
Biol. Pharm. Bull. |
pmid:22382320
|
Lin YC et al. |
The glutathionylation of p65 modulates NF-κB activity in 15-deoxy-Δ¹²,¹â´-prostaglandin Jâ‚‚-treated endothelial cells. |
2012 |
Free Radic. Biol. Med. |
pmid:22387200
|
Carsin A et al. |
[Physiopathology of aspirin intolerant asthma]. |
2012 |
Rev Mal Respir |
pmid:22405107
|
Song WL et al. |
Niacin and biosynthesis of PGDâ‚‚by platelet COX-1 in mice and humans. |
2012 |
J. Clin. Invest. |
pmid:22406532
|
Nagata N and Urade Y |
[Endogenous sleep-promoting substance]. |
2012 |
Nippon Rinsho |
pmid:22844810
|
Philipose S et al. |
Laropiprant attenuates EP3 and TP prostanoid receptor-mediated thrombus formation. |
2012 |
PLoS ONE |
pmid:22870195
|
Wingard CJ et al. |
Mast cells contribute to altered vascular reactivity and ischemia-reperfusion injury following cerium oxide nanoparticle instillation. |
2011 |
Nanotoxicology |
pmid:21043986
|
Joachim A and Ruttkowski B |
Prostaglandin D(2) synthesis in Oesophagostomum dentatum is mediated by cytosolic glutathione S-transferase. |
2011 |
Exp. Parasitol. |
pmid:21056037
|
Lotz C et al. |
Peroxisome-proliferator-activated receptor γ mediates the second window of anaesthetic-induced preconditioning. |
2011 |
Exp. Physiol. |
pmid:21123361
|
Tsujita T et al. |
Nitro-fatty acids and cyclopentenone prostaglandins share strategies to activate the Keap1-Nrf2 system: a study using green fluorescent protein transgenic zebrafish. |
2011 |
Genes Cells |
pmid:21143560
|
Neri T et al. |
Role of NF-kappaB and PPAR-gamma in lung inflammation induced by monocyte-derived microparticles. |
2011 |
Eur. Respir. J. |
pmid:21148223
|
Kumar VB et al. |
Angiogenic effect of laminin involves modulation of cyclooxygenase-2 and prostaglandin levels. |
2011 |
Exp. Biol. Med. (Maywood) |
pmid:21148739
|
Higuchi S et al. |
IL-4 mediates dicloxacillin-induced liver injury in mice. |
2011 |
Toxicol. Lett. |
pmid:21094227
|
Afrin LB |
Polycythemia from mast cell activation syndrome: lessons learned. |
2011 |
Am. J. Med. Sci. |
pmid:21642812
|
Kajiwara D et al. |
Role of hematopoietic prostaglandin D synthase in biphasic nasal obstruction in guinea pig model of experimental allergic rhinitis. |
2011 |
Eur. J. Pharmacol. |
pmid:21645503
|
Erttmann SF et al. |
PGD2 and PGE2 regulate gene expression of Prx 6 in primary macrophages via Nrf2. |
2011 |
Free Radic. Biol. Med. |
pmid:21651978
|
Chiba T et al. |
The opposing role of two prostaglandin D2 receptors, DP and CRTH2, in human eosinophil migration. |
2011 |
Ann. Allergy Asthma Immunol. |
pmid:21624751
|
Liu TY et al. |
[Advances in the study of histaminergic systems and sleep-wake regulation]. |
2011 |
Yao Xue Xue Bao |
pmid:21626776
|
Zhang Y et al. |
Simultaneous and high-throughput quantitation of urinary tetranor PGDM and tetranor PGEM by online SPE-LC-MS/MS as inflammatory biomarkers. |
2011 |
J Mass Spectrom |
pmid:21706677
|
Ugajin T et al. |
FcεRI, but not FcγR, signals induce prostaglandin D2 and E2 production from basophils. |
2011 |
Am. J. Pathol. |
pmid:21712025
|
Tobiasova Z et al. |
Peroxisome proliferator-activated receptor-γ agonists prevent in vivo remodeling of human artery induced by alloreactive T cells. |
2011 |
Circulation |
pmid:21690493
|
Ebersberger A et al. |
Effects of prostaglandin D2 on tetrodotoxin-resistant Na+ currents in DRG neurons of adult rat. |
2011 |
Pain |
pmid:21345590
|
Huang ZL et al. |
The role of adenosine in the regulation of sleep. |
2011 |
Curr Top Med Chem |
pmid:21401496
|
Osanai T and Okumura K |
Lipocalin-type PGD synthase as a novel biomarker for coronary vasospasm. |
2011 |
Circ. J. |
pmid:21378446
|
Du H et al. |
Inhibition of COX-2 expression by endocannabinoid 2-arachidonoylglycerol is mediated via PPAR-γ. |
2011 |
Br. J. Pharmacol. |
pmid:21501147
|
Varma D et al. |
Comparison of UHPLC and HPLC methods for the assay of prostanoids: "are the methods equivalent in terms of accuracy and precision?". |
2011 |
Bioanalysis |
pmid:21510759
|
Kamauchi S and Urade Y |
[Hematopoietic prostaglandin D synthase inhibitors for the treatment of duchenne muscular dystrophy]. |
2011 |
Brain Nerve |
pmid:22068479
|
Raman P et al. |
15-Deoxy-delta12,14-prostaglandin J2-glycerol ester, a putative metabolite of 2-arachidonyl glycerol, activates peroxisome proliferator activated receptor gamma. |
2011 |
Mol. Pharmacol. |
pmid:21511917
|
Leamy AW et al. |
Curcumin ((E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) activates and desensitizes the nociceptor ion channel TRPA1. |
2011 |
Neurosci. Lett. |
pmid:21855605
|
Lin TH et al. |
15-deoxy-Δ(12,14) -prostaglandin-J2 and ciglitazone inhibit TNF-α-induced matrix metalloproteinase 13 production via the antagonism of NF-κB activation in human synovial fibroblasts. |
2011 |
J. Cell. Physiol. |
pmid:21344384
|
Zheng S et al. |
Novel biphasic role of LipoxinA(4) on expression of cyclooxygenase-2 in lipopolysaccharide-stimulated lung fibroblasts. |
2011 |
Mediators Inflamm. |
pmid:21765620
|
Lalier L et al. |
Prostaglandins antagonistically control Bax activation during apoptosis. |
2011 |
Cell Death Differ. |
pmid:20966963
|
Hernandez JM and Janssen LJ |
Thromboxane prostanoid receptor activation amplifies airway stretch-activated contractions assessed in perfused intact bovine bronchial segments. |
2011 |
J. Pharmacol. Exp. Ther. |
pmid:21768224
|
Sharma I et al. |
In vitro effects of peroxisome proliferator-activated receptor-γ ligands on gene expression in lipopolysaccharide-induced endometrial and endometriotic stromal cells. |
2011 |
Fertil. Steril. |
pmid:20970133
|
Tanaka A et al. |
Mast cells function as an alternative modulator of adipogenesis through 15-deoxy-delta-12, 14-prostaglandin J2. |
2011 |
Am. J. Physiol., Cell Physiol. |
pmid:21865589
|
Larsson AK et al. |
Prostaglandin Dâ‚‚ induces contractions through activation of TP receptors in peripheral lung tissue from the guinea pig. |
2011 |
Eur. J. Pharmacol. |
pmid:21872585
|
Degousee N et al. |
Group V phospholipase A2 in bone marrow-derived myeloid cells and bronchial epithelial cells promotes bacterial clearance after Escherichia coli pneumonia. |
2011 |
J. Biol. Chem. |
pmid:21849511
|
Mesquita-Santos FP et al. |
Co-operative signalling through DP(1) and DP(2) prostanoid receptors is required to enhance leukotriene C(4) synthesis induced by prostaglandin D(2) in eosinophils. |
2011 |
Br. J. Pharmacol. |
pmid:20973774
|
Wienecke T et al. |
Discrepancy between strong cephalic arterial dilatation and mild headache caused by prostaglandin Dâ‚‚ (PGDâ‚‚). |
2011 |
Cephalalgia |
pmid:20974593
|
El-Shazly AE et al. |
IFN-γ and TNF-α potentiate prostaglandin D2-induced human eosinophil chemotaxis through up-regulation of CRTH2 surface receptor. |
2011 |
Int. Immunopharmacol. |
pmid:21835268
|
Kuehn HS et al. |
Prostaglandin E2 activates and utilizes mTORC2 as a central signaling locus for the regulation of mast cell chemotaxis and mediator release. |
2011 |
J. Biol. Chem. |
pmid:20980255
|
Surh YJ et al. |
15-Deoxy-Δ¹²,¹â´-prostaglandin Jâ‚‚, an electrophilic lipid mediator of anti-inflammatory and pro-resolving signaling. |
2011 |
Biochem. Pharmacol. |
pmid:21843512
|
Lu Y et al. |
Emodin, a naturally occurring anthraquinone derivative, suppresses IgE-mediated anaphylactic reaction and mast cell activation. |
2011 |
Biochem. Pharmacol. |
pmid:21907188
|
Burke SJ and Collier JJ |
The gene encoding cyclooxygenase-2 is regulated by IL-1β and prostaglandins in 832/13 rat insulinoma cells. |
2011 |
Cell. Immunol. |
pmid:21885043
|
Crosignani S et al. |
Discovery of potent, selective, and orally bioavailable alkynylphenoxyacetic acid CRTH2 (DP2) receptor antagonists for the treatment of allergic inflammatory diseases. |
2011 |
J. Med. Chem. |
pmid:21916510
|
Nabe T et al. |
Inhibition of hematopoietic prostaglandin D synthase improves allergic nasal blockage in guinea pigs. |
2011 |
Prostaglandins Other Lipid Mediat. |
pmid:21601002
|
Joos H et al. |
Single impact trauma in human early-stage osteoarthritic cartilage: implication of prostaglandin D2 but no additive effect of IL-1β on cell survival. |
2011 |
Int. J. Mol. Med. |
pmid:21567074
|
Shao Z et al. |
Choroidal involution is a key component of oxygen-induced retinopathy. |
2011 |
Invest. Ophthalmol. Vis. Sci. |
pmid:21546530
|
Ji Y et al. |
Nutrient-induced inflammation in the intestine. |
2011 |
Curr Opin Clin Nutr Metab Care |
pmid:21587069
|
Jakob S and Lovell-Badge R |
Sex determination and the control of Sox9 expression in mammals. |
2011 |
FEBS J. |
pmid:21281448
|
Hardy KD et al. |
Nonenzymatic free radical-catalyzed generation of 15-deoxy-Δ(12,14)-prostaglandin J₂-like compounds (deoxy-J₂-isoprostanes) in vivo. |
2011 |
J. Lipid Res. |
pmid:20944061
|
Wang P et al. |
Response of chondrocytes to shear stress: antagonistic effects of the binding partners Toll-like receptor 4 and caveolin-1. |
2011 |
FASEB J. |
pmid:21715681
|
Ahmed SR et al. |
Prostaglandin D2 regulates CD4+ memory T cell trafficking across blood vascular endothelium and primes these cells for clearance across lymphatic endothelium. |
2011 |
J. Immunol. |
pmid:21715691
|
Yu R et al. |
Competitive enzymatic interactions determine the relative amounts of prostaglandins E2 and D2. |
2011 |
J. Pharmacol. Exp. Ther. |
pmid:21865441
|
Koyama J et al. |
Simultaneous determination of histamine and prostaglandin D2 using an LC-ESI-MS/MS method with positive/negative ion-switching ionization modes: application to the study of anti-allergic flavonoids on the degranulation of KU812 cells. |
2011 |
Anal Bioanal Chem |
pmid:21725829
|