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Resident peritoneal macrophages and mast cells are important cellular sites of COX-1 and COX-2 activity during acute peritoneal inflammation. |
2009 Nov-Dec |
Arch. Immunol. Ther. Exp. (Warsz.) |
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Moreira V et al. |
Effects of Bothrops asper snake venom on the expression of cyclooxygenases and production of prostaglandins by peritoneal leukocytes in vivo, and by isolated neutrophils and macrophages in vitro. |
2009 Feb-Mar |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:19155166
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Csanky E et al. |
Lipid metabolite levels of prostaglandin D2 and eicosapentaenoic acid recovered from bronchoalveolar lavage fluid correlate with lung function of chronic obstructive pulmonary disease patients and controls. |
2009 |
Electrophoresis |
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Kase K et al. |
Inhibitory action of roxithromycin on histamine release and prostaglandin D2 production from beta-defensin 2-stimulated mast cells. |
2009 |
Int. J. Mol. Med. |
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The permissive role of mitochondria in the induction of haem oxygenase-1 in endothelial cells. |
2009 |
Biochem. J. |
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Lee DR et al. |
15-Deoxy-Delta(12,14)-prostaglandin J(2) induces mitochondrial-dependent apoptosis through inhibition of PKA/NF-kappaB in renal proximal epithelial cells. |
2009 |
Toxicology |
pmid:19167456
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Quarello E and Trabbia A |
High-definition flow combined with spatiotemporal image correlation in the diagnosis of fetal coarctation of the aorta. |
2009 |
Ultrasound Obstet Gynecol |
pmid:19194864
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Ishii T et al. |
Pivotal role of mast cells in pruritogenesis in patients with myeloproliferative disorders. |
2009 |
Blood |
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Passeron T et al. |
Upregulation of SOX9 inhibits the growth of human and mouse melanomas and restores their sensitivity to retinoic acid. |
2009 |
J. Clin. Invest. |
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Structural insight into PPARgamma activation through covalent modification with endogenous fatty acids. |
2009 |
J. Mol. Biol. |
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15-deoxy-Delta12,14 prostaglandin J2-induced heme oxygenase-1 in megakaryocytes regulates thrombopoiesis. |
2009 |
J. Thromb. Haemost. |
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15-Deoxy-Delta12,14-prostaglandin J2 inhibits HIV-1 transactivating protein, Tat, through covalent modification. |
2009 |
FASEB J. |
pmid:19299483
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Inhibition of prostaglandin D synthase suppresses muscular necrosis. |
2009 |
Am. J. Pathol. |
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Down-regulation of hTERT expression plays an important role in 15-deoxy-Delta12,14-prostaglandin J2-induced apoptosis in cancer cells. |
2009 |
Int. J. Oncol. |
pmid:19360348
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Boehme SA et al. |
Murine bone marrow-derived mast cells express chemoattractant receptor-homologous molecule expressed on T-helper class 2 cells (CRTh2). |
2009 |
Int. Immunol. |
pmid:19346259
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Involvement of Propionibacterium acnes in the augmentation of lipogenesis in hamster sebaceous glands in vivo and in vitro. |
2009 |
J. Invest. Dermatol. |
pmid:19282842
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Ferguson HE et al. |
Electrophilic peroxisome proliferator-activated receptor-gamma ligands have potent antifibrotic effects in human lung fibroblasts. |
2009 |
Am. J. Respir. Cell Mol. Biol. |
pmid:19286977
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Interaction between prostaglandin D and chemoattractant receptor-homologous molecule expressed on Th2 cells mediates cytokine production by Th2 lymphocytes in response to activated mast cells. |
2009 |
Clin. Exp. Immunol. |
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Increased production of cysteinyl leukotrienes and prostaglandin D2 during human anaphylaxis. |
2009 |
Clin. Exp. Allergy |
pmid:19128354
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Shin SW et al. |
15d-PGJ2 induces apoptosis by reactive oxygen species-mediated inactivation of Akt in leukemia and colorectal cancer cells and shows in vivo antitumor activity. |
2009 |
Clin. Cancer Res. |
pmid:19690198
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Elevated concentrations of 15-deoxy-Delta12,14-prostaglandin J2 in chronic liver disease propose therapeutic trials with peroxisome proliferator activated receptor gamma-inducing drugs. |
2009 |
Liver Int. |
pmid:19018984
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Kobayashi M et al. |
The antioxidant defense system Keap1-Nrf2 comprises a multiple sensing mechanism for responding to a wide range of chemical compounds. |
2009 |
Mol. Cell. Biol. |
pmid:19001094
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Biochemical, functional, and pharmacological characterization of AT-56, an orally active and selective inhibitor of lipocalin-type prostaglandin D synthase. |
2009 |
J. Biol. Chem. |
pmid:19131342
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CC16 inhibits the migration of eosinophils towards the formyl peptide fMLF but not towards PGD2. |
2009 |
Inflammation |
pmid:19132521
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15-Deoxy-Delta12,14-prostaglandin J2 upregulates the expression of heme oxygenase-1 and subsequently matrix metalloproteinase-1 in human breast cancer cells: possible roles of iron and ROS. |
2009 |
Carcinogenesis |
pmid:19136476
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Di Francesco L et al. |
Induction of prostacyclin by steady laminar shear stress suppresses tumor necrosis factor-alpha biosynthesis via heme oxygenase-1 in human endothelial cells. |
2009 |
Circ. Res. |
pmid:19122175
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PPAR-gamma agonists inhibit TGF-beta1-induced chemokine expression in human tubular epithelial cells. |
2009 |
Acta Pharmacol. Sin. |
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Atomic structure of mutant PPARgamma LBD complexed with 15d-PGJ2: novel modulation mechanism of PPARgamma/RXRalpha function by covalently bound ligands. |
2009 |
FEBS Lett. |
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Two different mechanisms for modulation of bronchoconstriction in guinea-pigs by cyclooxygenase metabolites. |
2009 |
Prostaglandins Other Lipid Mediat. |
pmid:19103301
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Suppression of pancreatic carcinoma growth by activating peroxisome proliferator-activated receptor gamma involves angiogenesis inhibition. |
2009 |
World J. Gastroenterol. |
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Eicosapentaenoic acid is more effective than docosahexaenoic acid in inhibiting proinflammatory mediator production and transcription from LPS-induced human asthmatic alveolar macrophage cells. |
2009 |
Clin Nutr |
pmid:19054597
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Intracellular protein phosphorylation in eosinophils and the functional relevance in cytokine production. |
2009 |
Int. Arch. Allergy Immunol. |
pmid:19494504
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15-Deoxy-Delta(12,14)-prostaglandin J2 induces IL-8 and GM-CSF in a human airway epithelial cell line (NCI-H292). |
2009 |
Int. Arch. Allergy Immunol. |
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Lipid peroxidation: physiological levels and dual biological effects. |
2009 |
Free Radic. Biol. Med. |
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15-deoxy-Delta(12,14)-prostaglandin J(2) inhibits fibrogenic response in human hepatoma cells. |
2009 |
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Regulation of Nrf2-dependent gene expression by 15-deoxy-Delta12,14-prostaglandin J2. |
2009 |
Free Radic. Biol. Med. |
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15-Deoxi-Delta(12,14)-prostaglandin J2 is a tubulin-binding agent that destabilizes microtubules and induces mitotic arrest. |
2009 |
Biochem. Pharmacol. |
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GIF-0173 protects against cerebral infarction through DP1 receptor activation. |
2009 |
Exp. Neurol. |
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Peroxisome proliferator-activated receptor-gamma agonists promote differentiation and antioxidant defenses of oligodendrocyte progenitor cells. |
2009 |
J. Neuropathol. Exp. Neurol. |
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Plasma levels of 15d-PGJ are not altered in multiple sclerosis. |
2009 |
Eur. J. Neurol. |
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Qin HD et al. |
Upregulation of peroxisome proliferator-activated receptor-gamma and NADPH oxidases are involved in restenosis after balloon injury. |
2009 |
J. Cell. Physiol. |
pmid:19562688
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Functional selectivity of natural and synthetic prostaglandin EP4 receptor ligands. |
2009 |
J. Pharmacol. Exp. Ther. |
pmid:19584306
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Bai G et al. |
Regulation of ANP secretion from isolated atria by prostaglandins and cyclooxygenase-2. |
2009 |
Peptides |
pmid:19539681
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Subchronic infusion of the product of inflammation prostaglandin J2 models sporadic Parkinson's disease in mice. |
2009 |
J Neuroinflammation |
pmid:19630993
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Li H and Pauza CD |
Effects of 15-deoxy-delta12,14-prostaglandin J2 (15d-PGJ2) and rosiglitazone on human gammadelta2 T cells. |
2009 |
PLoS ONE |
pmid:19888466
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Landrier JF et al. |
Adiponectin expression is induced by vitamin E via a peroxisome proliferator-activated receptor gamma-dependent mechanism. |
2009 |
Endocrinology |
pmid:19833717
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Lauring B et al. |
Laropiprant in combination with extended-release niacin does not alter urine 11-dehydrothromboxane B2, a marker of in vivo platelet function, in healthy, hypercholesterolemic, and diabetic subjects. |
2009 |
J Clin Pharmacol |
pmid:19833861
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Hironaka A et al. |
15-Deoxy-Delta(12,14)-prostaglandin J(2) impairs the functions of histone acetyltransferases through their insolubilization in cells. |
2009 |
Biochem. Biophys. Res. Commun. |
pmid:19799872
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Ohinata K et al. |
Complement C5a stimulates food intake via a prostaglandin D(2)- and neuropeptide Y-dependent mechanism in mice. |
2009 |
Prostaglandins Other Lipid Mediat. |
pmid:19800413
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Tagen M et al. |
Mitochondrial uncoupling protein 2 inhibits mast cell activation and reduces histamine content. |
2009 |
J. Immunol. |
pmid:19846869
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