Gates D et al. |
Apo J/clusterin expression and secretion: evidence for 15-deoxy-Δ(12,14)-PGJ(2)-dependent mechanism. |
2012 |
Biochim. Biophys. Acta |
pmid:22138303
|
Woodward DF et al. |
Thromboxane A2-mimetics are potent microvascular permeability factors in the conjunctiva. |
1990 |
J. Pharmacol. Exp. Ther. |
pmid:2213558
|
Kawano S et al. |
Protective effect of PGD2 against ethanol-induced gastric mucosal injury in rats. |
1990 |
J. Clin. Gastroenterol. |
pmid:2212542
|
Wang Y et al. |
Optimization of phenylacetic acid derivatives for CRTH2 and DP selective antagonism. |
2012 |
Bioorg. Med. Chem. Lett. |
pmid:22119474
|
Bain G et al. |
Pharmacodynamics, pharmacokinetics, and safety of AM211: a novel and potent antagonist of the prostaglandin D2 receptor type 2. |
2012 |
J Clin Pharmacol |
pmid:22110163
|
Tzung SP et al. |
Suppression of hepatic lymphokine-activated killer cell induction by murine Kupffer cells and hepatocytes. |
1990 |
Hepatology |
pmid:2210667
|
Murata T et al. |
Prostagladin D2 is a mast cell-derived antiangiogenic factor in lung carcinoma. |
2011 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:22106279
|
Pettipher R et al. |
Pharmacologic profile of OC000459, a potent, selective, and orally active D prostanoid receptor 2 antagonist that inhibits mast cell-dependent activation of T helper 2 lymphocytes and eosinophils. |
2012 |
J. Pharmacol. Exp. Ther. |
pmid:22106101
|
Braciale TJ and Kim TS |
Slowing down with age: lung DCs do it too. |
2011 |
J. Clin. Invest. |
pmid:22105176
|
Zhao J et al. |
Age-related increases in PGD(2) expression impair respiratory DC migration, resulting in diminished T cell responses upon respiratory virus infection in mice. |
2011 |
J. Clin. Invest. |
pmid:22105170
|
Luna-Gomes T et al. |
Eosinophils as a novel cell source of prostaglandin D2: autocrine role in allergic inflammation. |
2011 |
J. Immunol. |
pmid:22102725
|
Hossain MS et al. |
Stable expression of lipocalin-type prostaglandin D synthase in cultured preadipocytes impairs adipogenesis program independently of endogenous prostanoids. |
2012 |
Exp. Cell Res. |
pmid:22100987
|
Wang P et al. |
Interleukin-6 synthesis in human chondrocytes is regulated via the antagonistic actions of prostaglandin (PG)E2 and 15-deoxy-Δ(12,14)-PGJ2. |
2011 |
PLoS ONE |
pmid:22096605
|
He S et al. |
Identification, organ expression and ligand-dependent expression levels of peroxisome proliferator activated receptors in grass carp (Ctenopharyngodon idella). |
2012 |
Comp. Biochem. Physiol. C Toxicol. Pharmacol. |
pmid:22079418
|
Kamauchi S and Urade Y |
[Hematopoietic prostaglandin D synthase inhibitors for the treatment of duchenne muscular dystrophy]. |
2011 |
Brain Nerve |
pmid:22068479
|
Fujimori K et al. |
Prevention of paraquat-induced apoptosis in human neuronal SH-SY5Y cells by lipocalin-type prostaglandin D synthase. |
2012 |
J. Neurochem. |
pmid:22043816
|
Shinozawa T et al. |
Tetranor PGDM analyses for the amyotrophic lateral sclerosis: positive and simple diagnosis and evaluation of drug effect. |
2011 |
Biochem. Biophys. Res. Commun. |
pmid:22027143
|
Urade Y and Hayaishi O |
Prostaglandin D2 and sleep/wake regulation. |
2011 |
Sleep Med Rev |
pmid:22024172
|
Seno T et al. |
15-Deoxy-Δ¹²,¹ⴠprostaglandin J₂ reduces the formation of atherosclerotic lesions in apolipoprotein E knockout mice. |
2011 |
PLoS ONE |
pmid:22003398
|
Wang JJ and Mak OT |
Induction of apoptosis in non-small cell lung carcinoma A549 cells by PGDâ‚‚ metabolite, 15d-PGJâ‚‚. |
2011 |
Cell Biol. Int. |
pmid:21999315
|
Chang MC et al. |
Antiplatelet effect by p-cresol, a uremic and environmental toxicant, is related to inhibition of reactive oxygen species, ERK/p38 signaling and thromboxane A2 production. |
2011 |
Atherosclerosis |
pmid:21993412
|
Jin M et al. |
Anti-inflammatory activity of 6-hydroxy-2,7-dimethoxy-1,4-henanthraquinone from tuberous roots of yam (Dioscorea batatas) through inhibition of prostaglandin Dâ‚‚ and leukotriene Câ‚„ production in mouse bone marrow-derived mast cells. |
2011 |
Arch. Pharm. Res. |
pmid:21975811
|
de Jong E et al. |
Anticancer effects of 15d-prostaglandin-J2 in wild-type and doxorubicin-resistant ovarian cancer cells: novel actions on SIRT1 and HDAC. |
2011 |
PLoS ONE |
pmid:21957481
|
Matsushima Y et al. |
Distinct roles of prostaglandin D2 receptors in chronic skin inflammation. |
2011 |
Mol. Immunol. |
pmid:21943706
|
De Nuccio C et al. |
Peroxisome proliferator-activated receptor γ agonists accelerate oligodendrocyte maturation and influence mitochondrial functions and oscillatory Ca(2+) waves. |
2011 |
J. Neuropathol. Exp. Neurol. |
pmid:21937914
|
Sedej M et al. |
D-type prostanoid receptor enhances the signaling of chemoattractant receptor-homologous molecule expressed on T(H)2 cells. |
2012 |
J. Allergy Clin. Immunol. |
pmid:21930295
|
Tao H and Hajri T |
Very low density lipoprotein receptor promotes adipocyte differentiation and mediates the proadipogenic effect of peroxisome proliferator-activated receptor gamma agonists. |
2011 |
Biochem. Pharmacol. |
pmid:21924248
|
Crosignani S et al. |
Discovery of potent, selective, and orally bioavailable alkynylphenoxyacetic acid CRTH2 (DP2) receptor antagonists for the treatment of allergic inflammatory diseases. |
2011 |
J. Med. Chem. |
pmid:21916510
|
Lu Y et al. |
Emodin, a naturally occurring anthraquinone derivative, suppresses IgE-mediated anaphylactic reaction and mast cell activation. |
2011 |
Biochem. Pharmacol. |
pmid:21907188
|
Maicas N et al. |
Prostaglandin D2 regulates joint inflammation and destruction in murine collagen-induced arthritis. |
2012 |
Arthritis Rheum. |
pmid:21898357
|
Kanai Y et al. |
Identification of novel oxidized levuglandin D2 in marine red alga and mouse tissue. |
2011 |
J. Lipid Res. |
pmid:21893678
|
Moniot B et al. |
Hematopoietic prostaglandin D synthase (H-Pgds) is expressed in the early embryonic gonad and participates to the initial nuclear translocation of the SOX9 protein. |
2011 |
Dev. Dyn. |
pmid:21887724
|
Burke SJ and Collier JJ |
The gene encoding cyclooxygenase-2 is regulated by IL-1β and prostaglandins in 832/13 rat insulinoma cells. |
2011 |
Cell. Immunol. |
pmid:21885043
|
Larsson AK et al. |
Prostaglandin Dâ‚‚ induces contractions through activation of TP receptors in peripheral lung tissue from the guinea pig. |
2011 |
Eur. J. Pharmacol. |
pmid:21872585
|
Tanaka A et al. |
Mast cells function as an alternative modulator of adipogenesis through 15-deoxy-delta-12, 14-prostaglandin J2. |
2011 |
Am. J. Physiol., Cell Physiol. |
pmid:21865589
|
Yu R et al. |
Competitive enzymatic interactions determine the relative amounts of prostaglandins E2 and D2. |
2011 |
J. Pharmacol. Exp. Ther. |
pmid:21865441
|
Leamy AW et al. |
Curcumin ((E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) activates and desensitizes the nociceptor ion channel TRPA1. |
2011 |
Neurosci. Lett. |
pmid:21855605
|
Miyawaki T et al. |
Combination of midazolam and a cyclooxygenase-2 inhibitor inhibits lipopolysaccharide-induced interleukin-6 production in human peripheral blood mononuclear cells. |
2012 |
Immunopharmacol Immunotoxicol |
pmid:21854184
|
Chae HS and Chin YW |
Anti-allergic effect of lambertianic acid from Thuja orientalis in mouse bone marrow-derived mast cells. |
2012 |
Immunopharmacol Immunotoxicol |
pmid:21854102
|
Degousee N et al. |
Group V phospholipase A2 in bone marrow-derived myeloid cells and bronchial epithelial cells promotes bacterial clearance after Escherichia coli pneumonia. |
2011 |
J. Biol. Chem. |
pmid:21849511
|
Surh YJ et al. |
15-Deoxy-Δ¹²,¹â´-prostaglandin Jâ‚‚, an electrophilic lipid mediator of anti-inflammatory and pro-resolving signaling. |
2011 |
Biochem. Pharmacol. |
pmid:21843512
|
El-Shazly AE et al. |
IFN-γ and TNF-α potentiate prostaglandin D2-induced human eosinophil chemotaxis through up-regulation of CRTH2 surface receptor. |
2011 |
Int. Immunopharmacol. |
pmid:21835268
|
Choi YH et al. |
The extracellular signal-regulated kinase mitogen-activated protein kinase/ribosomal S6 protein kinase 1 cascade phosphorylates cAMP response element-binding protein to induce MUC5B gene expression via D-prostanoid receptor signaling. |
2011 |
J. Biol. Chem. |
pmid:21832046
|
Flachs P et al. |
Synergistic induction of lipid catabolism and anti-inflammatory lipids in white fat of dietary obese mice in response to calorie restriction and n-3 fatty acids. |
2011 |
Diabetologia |
pmid:21779874
|
Nakahata N et al. |
PGJ2 and delta 12PGJ2 inhibit cell growth accompanied with inhibition of phosphoinositide turnover in human astrocytoma cells. |
1990 |
Prostaglandins |
pmid:2177901
|
Hernandez JM and Janssen LJ |
Thromboxane prostanoid receptor activation amplifies airway stretch-activated contractions assessed in perfused intact bovine bronchial segments. |
2011 |
J. Pharmacol. Exp. Ther. |
pmid:21768224
|
Zheng S et al. |
Novel biphasic role of LipoxinA(4) on expression of cyclooxygenase-2 in lipopolysaccharide-stimulated lung fibroblasts. |
2011 |
Mediators Inflamm. |
pmid:21765620
|
Bardelli C et al. |
Autocrine activation of human monocyte/macrophages by monocyte-derived microparticles and modulation by PPARγ ligands. |
2012 |
Br. J. Pharmacol. |
pmid:21745193
|
Higuchi S et al. |
Involvement of Th2 cytokines in the mouse model of flutamide-induced acute liver injury. |
2012 |
J Appl Toxicol |
pmid:21735453
|
Eriksson LO et al. |
Prostaglandin E2 binding sites in human renal tissue: characterization and localization by radioligand binding and autoradiography. |
1990 |
Acta Physiol. Scand. |
pmid:2173350
|
Song NY et al. |
Multidrug resistance-associated protein 1 mediates 15-deoxy-Δ(12,14)-prostaglandin J2-induced expression of glutamate cysteine ligase expression via Nrf2 signaling in human breast cancer cells. |
2011 |
Chem. Res. Toxicol. |
pmid:21728338
|
Chowdhury AA et al. |
Sustained expression of lipocalin-type prostaglandin D synthase in the antisense direction positively regulates adipogenesis in cloned cultured preadipocytes. |
2011 |
Biochem. Biophys. Res. Commun. |
pmid:21726533
|
Koyama J et al. |
Simultaneous determination of histamine and prostaglandin D2 using an LC-ESI-MS/MS method with positive/negative ion-switching ionization modes: application to the study of anti-allergic flavonoids on the degranulation of KU812 cells. |
2011 |
Anal Bioanal Chem |
pmid:21725829
|
Cichocka-Jarosz E et al. |
Serum tryptase level is a better predictor of systemic side effects than prostaglandin D2 metabolites during venom immunotherapy in children. |
2011 |
J Investig Allergol Clin Immunol |
pmid:21721371
|
Ahmed SR et al. |
Prostaglandin D2 regulates CD4+ memory T cell trafficking across blood vascular endothelium and primes these cells for clearance across lymphatic endothelium. |
2011 |
J. Immunol. |
pmid:21715691
|
Wang P et al. |
Response of chondrocytes to shear stress: antagonistic effects of the binding partners Toll-like receptor 4 and caveolin-1. |
2011 |
FASEB J. |
pmid:21715681
|
Ugajin T et al. |
FcεRI, but not FcγR, signals induce prostaglandin D2 and E2 production from basophils. |
2011 |
Am. J. Pathol. |
pmid:21712025
|
Seiler S et al. |
SQ-27986 inhibition of platelet aggregation is mediated through activation of platelet prostaglandin D2 receptors. |
1990 |
Prostaglandins |
pmid:2171039
|
Zhang Y et al. |
Simultaneous and high-throughput quantitation of urinary tetranor PGDM and tetranor PGEM by online SPE-LC-MS/MS as inflammatory biomarkers. |
2011 |
J Mass Spectrom |
pmid:21706677
|
Yamamoto Y et al. |
Dual functions of prostaglandin D2 in murine contact hypersensitivity via DP and CRTH2. |
2011 |
Am. J. Pathol. |
pmid:21703412
|
Chowdhury AA et al. |
15-Deoxy-Δ(12,14)-prostaglandin J(2) interferes inducible synthesis of prostaglandins E(2) and F(2α) that suppress subsequent adipogenesis program in cultured preadipocytes. |
2011 |
Prostaglandins Other Lipid Mediat. |
pmid:21699992
|
Winter JS et al. |
A stimulatory effect of interleukin-1 on adrenocortical cortisol secretion mediated by prostaglandins. |
1990 |
Endocrinology |
pmid:2169407
|
Bettazzoli L et al. |
Incorporation of arachidonic acid into glycerophospholipids of a murine bone marrow derived mast cell. |
1990 |
Adv. Prostaglandin Thromboxane Leukot. Res. |
pmid:2169185
|
Menon R et al. |
Amniotic fluid eicosanoids in preterm and term births: effects of risk factors for spontaneous preterm labor. |
2011 |
Obstet Gynecol |
pmid:21691170
|
Tobiasova Z et al. |
Peroxisome proliferator-activated receptor-γ agonists prevent in vivo remodeling of human artery induced by alloreactive T cells. |
2011 |
Circulation |
pmid:21690493
|
Bennegård B et al. |
Luteotropic effects of prostaglandins I2 and D2 on isolated human corpora luteum. |
1990 |
Fertil. Steril. |
pmid:2168845
|
Yamamoto Y et al. |
15-Deoxy-Δ12,14-prostaglandin J2 enhanced the anti-tumor activity of camptothecin against renal cell carcinoma independently of topoisomerase-II and PPARγ pathways. |
2011 |
Biochem. Biophys. Res. Commun. |
pmid:21683069
|
Ulivi V et al. |
Anti-inflammatory activity of monogalactosyldiacylglycerol in human articular cartilage in vitro: activation of an anti-inflammatory cyclooxygenase-2 (COX-2) pathway. |
2011 |
Arthritis Res. Ther. |
pmid:21682897
|
Cha B et al. |
15-deoxy-D12,14-prostaglandin J2 suppresses RANTES expression by inhibiting NADPH oxidase activation in Helicobacter pylori-infected gastric epithelial cells. |
2011 |
J. Physiol. Pharmacol. |
pmid:21673364
|
Ayoub SS et al. |
Cyclooxygenase expression and prostaglandin levels in central nervous system tissues during the course of chronic relapsing experimental autoimmune encephalomyelitis (EAE). |
2011 |
Inflamm. Res. |
pmid:21667309
|
Erttmann SF et al. |
PGD2 and PGE2 regulate gene expression of Prx 6 in primary macrophages via Nrf2. |
2011 |
Free Radic. Biol. Med. |
pmid:21651978
|
Kajiwara D et al. |
Role of hematopoietic prostaglandin D synthase in biphasic nasal obstruction in guinea pig model of experimental allergic rhinitis. |
2011 |
Eur. J. Pharmacol. |
pmid:21645503
|
Afrin LB |
Polycythemia from mast cell activation syndrome: lessons learned. |
2011 |
Am. J. Med. Sci. |
pmid:21642812
|
Liu TY et al. |
[Advances in the study of histaminergic systems and sleep-wake regulation]. |
2011 |
Yao Xue Xue Bao |
pmid:21626776
|
Chiba T et al. |
The opposing role of two prostaglandin D2 receptors, DP and CRTH2, in human eosinophil migration. |
2011 |
Ann. Allergy Asthma Immunol. |
pmid:21624751
|
Nabe T et al. |
Inhibition of hematopoietic prostaglandin D synthase improves allergic nasal blockage in guinea pigs. |
2011 |
Prostaglandins Other Lipid Mediat. |
pmid:21601002
|
Ito S et al. |
Evaluation of ZK110841 and AH6809, an agonist and an antagonist of prostaglandin DP-receptors on human platelets, with a PGD2-responsive cell line from bovine embryonic trachea. |
1990 |
Br. J. Pharmacol. |
pmid:2158830
|
Ji Y et al. |
Nutrient-induced inflammation in the intestine. |
2011 |
Curr Opin Clin Nutr Metab Care |
pmid:21587069
|
Brass EP and Garrity MJ |
Structural specificity for prostaglandin effects on hepatocyte glycogenolysis. |
1990 |
Biochem. J. |
pmid:2158311
|
Joos H et al. |
Single impact trauma in human early-stage osteoarthritic cartilage: implication of prostaglandin D2 but no additive effect of IL-1β on cell survival. |
2011 |
Int. J. Mol. Med. |
pmid:21567074
|
Shao Z et al. |
Choroidal involution is a key component of oxygen-induced retinopathy. |
2011 |
Invest. Ophthalmol. Vis. Sci. |
pmid:21546530
|
Gadsby JE et al. |
Prostaglandin F2 alpha receptors on enzyme-dissociated pig luteal cells throughout the estrous cycle. |
1990 |
Endocrinology |
pmid:2153525
|
Raman P et al. |
15-Deoxy-delta12,14-prostaglandin J2-glycerol ester, a putative metabolite of 2-arachidonyl glycerol, activates peroxisome proliferator activated receptor gamma. |
2011 |
Mol. Pharmacol. |
pmid:21511917
|
Varma D et al. |
Comparison of UHPLC and HPLC methods for the assay of prostanoids: "are the methods equivalent in terms of accuracy and precision?". |
2011 |
Bioanalysis |
pmid:21510759
|
Du H et al. |
Inhibition of COX-2 expression by endocannabinoid 2-arachidonoylglycerol is mediated via PPAR-γ. |
2011 |
Br. J. Pharmacol. |
pmid:21501147
|
Williams WR et al. |
In vitro tests for the diagnosis of aspirin-sensitive asthma. |
1990 |
J. Allergy Clin. Immunol. |
pmid:2146311
|
Vigano' T et al. |
Binding sites for histamine and sulfidopeptide leukotrienes in normal and hypersensitized human lung fragments. |
1990 |
Adv. Prostaglandin Thromboxane Leukot. Res. |
pmid:2144691
|
Yamamoto Y et al. |
Proteomic identification of protein targets for 15-deoxy-Δ(12,14)-prostaglandin J2 in neuronal plasma membrane. |
2011 |
PLoS ONE |
pmid:21445266
|
Arima M and Fukuda T |
Prostaglandin Dâ‚‚ and T(H)2 inflammation in the pathogenesis of bronchial asthma. |
2011 |
Korean J. Intern. Med. |
pmid:21437156
|
Virgolini I et al. |
Effects of bopindolol on platelet function in hypertension at rest and during exercise. |
1990 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:2143586
|
Mackay GA and Stewart AG |
R2D(2) for C(4)Eo: an 'alliance' of PGD(2) receptors is required for LTC(4) production by human eosinophils. |
2011 |
Br. J. Pharmacol. |
pmid:21426314
|
Featherstone RL et al. |
Evidence for thromboxane receptor mediated contraction of guinea-pig and human airways in vitro by prostaglandin (PG) D2, 9 alpha,11 beta-PGF2 and PGF2 alpha. |
1990 |
Naunyn Schmiedebergs Arch. Pharmacol. |
pmid:2142256
|
Huang ZL et al. |
The role of adenosine in the regulation of sleep. |
2011 |
Curr Top Med Chem |
pmid:21401496
|
Wang JJ and Mak OT |
Induction of apoptosis by 15d-PGJ2 via ROS formation: an alternative pathway without PPARγ activation in non-small cell lung carcinoma A549 cells. |
2011 |
Prostaglandins Other Lipid Mediat. |
pmid:21396480
|
Imura Y et al. |
Antagonistic action of AA-2414 on thromboxane A2/prostaglandin endoperoxide receptor in platelets and blood vessels. |
1990 |
Jpn. J. Pharmacol. |
pmid:2137886
|
Osanai T and Okumura K |
Lipocalin-type PGD synthase as a novel biomarker for coronary vasospasm. |
2011 |
Circ. J. |
pmid:21378446
|
Kane CJ et al. |
Protection of neurons and microglia against ethanol in a mouse model of fetal alcohol spectrum disorders by peroxisome proliferator-activated receptor-γ agonists. |
2011 |
Brain Behav. Immun. |
pmid:21376806
|
Maekawa N et al. |
High-performance affinity purification for identification of 15-deoxy-Δ 12,14 -PGJ₂ interacting factors using magnetic nanobeads. |
2011 |
Biomed. Chromatogr. |
pmid:21374648
|
Luker T et al. |
Zwitterionic CRTh2 antagonists. |
2011 |
J. Med. Chem. |
pmid:21355602
|
Farhat A et al. |
Hematopoietic-Prostaglandin D2 synthase through PGD2 production is involved in the adult ovarian physiology. |
2011 |
J Ovarian Res |
pmid:21352547
|