PGD2

Pgd2 is a lipid of Fatty Acyls (FA) class. Pgd2 is associated with abnormalities such as Inflammatory disorder, Pleurisy, Rhinitis, Dehydration and Pneumonia. The involved functions are known as antagonists, fat cell differentiation, Phosphorylation, Process and Gene Expression. Pgd2 often locates in Cell surface, Body tissue, Extracellular, Bone Marrow and Membrane. The associated genes with PGD2 are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, P4HTM gene, PTGS2 gene, PTGDS gene and IL3 gene. The related lipids are 15-deoxyprostaglandin J2, Nonesterified Fatty Acids, Lipopolysaccharides, Steroids and Liposomes. The related experimental models are Knock-out and Rodent Model.

Cross Reference

Introduction

To understand associated biological information of PGD2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with PGD2?

PGD2 is suspected in Asthma, Dehydration, Allergic rhinitis NOS, Rhinitis, Infertility, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with PGD2

MeSH term MeSH ID Detail
Encephalitis D004660 15 associated lipids
Hyperlipoproteinemias D006951 15 associated lipids
Astrocytoma D001254 15 associated lipids
Dyskinesia, Drug-Induced D004409 15 associated lipids
HIV Seropositivity D006679 15 associated lipids
Thrombocytopenia D013921 15 associated lipids
Bronchial Hyperreactivity D016535 15 associated lipids
Blister D001768 16 associated lipids
Adenomatous Polyposis Coli D011125 16 associated lipids
Subarachnoid Hemorrhage D013345 17 associated lipids
Per page 10 20 50 100 | Total 189

PubChem Associated disorders and diseases

What pathways are associated with PGD2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with PGD2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with PGD2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with PGD2?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with PGD2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with PGD2?

Knock-out

Knock-out are used in the study 'Multiple roles of the prostaglandin D2 signaling pathway in reproduction.' (Rossitto M et al., 2015).

Rodent Model

Rodent Model are used in the study 'PKA regulatory IIα subunit is essential for PGD2-mediated resolution of inflammation.' (Kong D et al., 2016).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with PGD2

Download all related citations
Per page 10 20 50 100 | Total 3138
Authors Title Published Journal PubMed Link
Ahlquist DA et al. Factors influencing metabolism of arachidonic acid in guinea pig gastric mucosa. 1983 Am. J. Physiol. pmid:6401937
Whittle BJ et al. Platelet and cardiovascular activity of the hydantoin BW245C, a potent prostaglandin analogue. 1983 Prostaglandins pmid:6344147
Homma T and Malik KU Effect of secretin and caerulein in canine pancreas: relation to prostaglandins. 1983 Am. J. Physiol. pmid:6344655
Naclerio RM et al. Mediator release after nasal airway challenge with allergen. 1983 Am. Rev. Respir. Dis. pmid:6354022
Inoué S [Sleep substances: their roles and evolution]. 1983 Seikagaku pmid:6355327
Tasaka K et al. Prostaglandin D2 induces release of luteinizing hormone from the rat pituitary gland without the modulation of hypothalamic luteinizing hormone releasing hormone. 1983 J. Endocrinol. pmid:6361197
Schleimer RP et al. Effects of dexamethasone on mediator release from human lung fragments and purified human lung mast cells. 1983 J. Clin. Invest. pmid:6134755
Osama H et al. Inhibition of brain prostaglandin D synthetase and prostaglandin D2 dehydrogenase by some saturated and unsaturated fatty acids. 1983 Biochim. Biophys. Acta pmid:6407532
Scott HW et al. Hazards in operative management of patients with systemic mastocytosis. 1983 Ann. Surg. pmid:6189461
Stringfellow DA Prostaglandins and metastasis. 1983 Symp Fundam Cancer Res pmid:6206537
Feinstein MB et al. The cytoplasmic concentration of free calcium in platelets is controlled by stimulators of cyclic AMP production (PGD2, PGE1, forskolin). 1983 Biochem. Biophys. Res. Commun. pmid:6307295
Fitzpatrick FA and Wynalda MA Albumin-catalyzed metabolism of prostaglandin D2. Identification of products formed in vitro. 1983 J. Biol. Chem. pmid:6578214
Juhlin L et al. Effect of infrared irradiation on the recoverable levels of free arachidonic acid and prostaglandins in human forearm skin. 1983 J. Invest. Dermatol. pmid:6578272
Ruzicka T et al. Changes in arachidonic acid metabolism in UV-irradiated hairless mouse skin. 1983 J. Invest. Dermatol. pmid:6578273
Soifer SJ et al. The developmental effects of prostaglandin D2 on the pulmonary and systemic circulations in the newborn lamb. 1983 J. Dev. Physiol. pmid:6579103
Miyake A et al. Prostaglandin D2 stimulates secretion of luteinizing hormone from pituitary gland in vitro. 1983 Acta Endocrinol. pmid:6579807
Belegu M et al. beta-Adrenergic blockade of prostaglandin E2- and D2-induced erythroid colony formation. 1983 Am. J. Physiol. pmid:6579847
Lysz TW et al. Measurement of prostaglandin biosynthetic capacity in discrete areas of the rabbit hippocampal formation. 1983 J. Neurosci. Res. pmid:6580469
Ishizawa M Contractile effects of PGD2 and PGF2 alpha on mechanical and electrical activities in longitudinal and circular muscles of the guinea-pig colon. 1983 Prostaglandins pmid:6580679
Bregman MD and Meyskens FL In vitro modulation of human and murine melanoma growth by prostanoid analogues. 1983 Prostaglandins pmid:6581509