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Sexually dimorphic development of mouse primordial germ cells: switching from oogenesis to spermatogenesis. |
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Cold temperatures reduce the sensitivity of stored platelets to disaggregating agents. |
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Phospholipase C inhibitors and prostaglandins differentially regulate phosphatidylcholine synthesis in rat renal papilla. Evidence of compartmental regulation of CTP:phosphocholine cytidylyltransferase and CDP-choline:1,2-diacylglycerol cholinephosphotransferase. |
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Modulation of nitric oxide concentration and lipid metabolism by 15-deoxy Delta12,14prostaglandin J2 in embryos from control and diabetic rats during early organogenesis. |
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Reproduction |
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A key role for old yellow enzyme in the metabolism of drugs by Trypanosoma cruzi. |
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Peroxisome proliferators compete and ameliorate Hcy-mediated endocardial endothelial cell activation. |
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Am. J. Physiol., Cell Physiol. |
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Indomethacin causes prostaglandin D(2)-like and eotaxin-like selective responses in eosinophils and basophils. |
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Prostaglandin D2 generation by rat peritoneal mast cells stimulated with Datura stramonium agglutinin and its inhibition by haptenic sugar and wheat germ agglutinin. |
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Molecular pharmacology of the human prostaglandin D2 receptor, CRTH2. |
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15-PGJ2, but not thiazolidinediones, inhibits cell growth, induces apoptosis, and causes downregulation of Stat3 in human oral SCCa cells. |
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Br. J. Cancer |
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15d-PGJ(2) is acting as a 'dual agent' on the regulation of COX-2 expression in human osteoarthritic chondrocytes. |
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15-deoxy-Delta 12,14-prostaglandin J2 induces apoptosis of human hepatic myofibroblasts. A pathway involving oxidative stress independently of peroxisome-proliferator-activated receptors. |
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Prostaglandins Other Lipid Mediat. |
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Chemoprevention of azoxymethane-induced rat aberrant crypt foci by dietary zerumbone isolated from Zingiber zerumbet. |
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The Cycloxygenase-2 inhibitor SC58236 is neuroprotective in an in vivo model of focal ischemia in the rat. |
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Feedback control of the arachidonate cascade in rheumatoid synoviocytes by 15-deoxy-Delta(12,14)-prostaglandin J2. |
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Inhibition of cellular proliferation through IkappaB kinase-independent and peroxisome proliferator-activated receptor gamma-dependent repression of cyclin D1. |
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Peroxisome proliferator-activated receptor gamma-retinoid X receptor agonists increase CD36-dependent phagocytosis of Plasmodium falciparum-parasitized erythrocytes and decrease malaria-induced TNF-alpha secretion by monocytes/macrophages. |
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J. Immunol. |
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Profile of eicosanoids produced by human saphenous vein endothelial cells and the effect of dietary fatty acids. |
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Prostaglandins Leukot. Essent. Fatty Acids |
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Role of the parasite-derived prostaglandin D2 in the inhibition of epidermal Langerhans cell migration during schistosomiasis infection. |
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Persistent wheezing in very young children is associated with lower respiratory inflammation. |
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Modulation of the immediate allergic wheal reaction in the skin by drugs inhibiting the effects of leukotriene C4 and prostaglandin D2. |
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Adipophilin is a sensitive marker for lipid loading in human blood monocytes. |
2001 |
Biochim. Biophys. Acta |
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Release of markedly increased quantities of prostaglandin D2 from the skin in vivo in humans after the application of cinnamic aldehyde. |
2001 |
J. Am. Acad. Dermatol. |
pmid:11423836
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Role of prostaglandins in bladder smooth muscle cell gene expression. |
2001 |
Urology |
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NQ-Y15 inhibits the calcium mobilization by elevation of cyclic AMP in rat platelets. |
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Biol. Pharm. Bull. |
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PPAR gamma: an essential role in metabolic control. |
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Characterization of the lysyl adducts of prostaglandin H-synthases that are derived from oxygenation of arachidonic acid. |
2001 |
Biochemistry |
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Dual function of troglitazone in ICAM-1 gene expression in human vascular endothelium. |
2001 |
Biochem. Biophys. Res. Commun. |
pmid:11401521
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Modulation of intracellular cyclic AMP in immunologically activated rat peritoneal mast cells by prostaglandin D2. |
2001 |
Inflamm. Res. |
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Novel antiinflammatory targets for asthma. A role for PPARgamma? |
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Am. J. Respir. Cell Mol. Biol. |
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Peroxisome proliferator-activated receptor-gamma regulates airway epithelial cell activation. |
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Comparative actions of insulin sensitizers on ion channels in vascular smooth muscle. |
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Eur. J. Pharmacol. |
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Differential regulation of chemokine gene expression by 15-deoxy-delta 12,14 prostaglandin J2. |
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J. Immunol. |
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Serum prostaglandin D synthase level after coronary angioplasty may predict occurrence of restenosis. |
2001 |
Thromb. Haemost. |
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Prostaglandin D2 selectively induces chemotaxis in T helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2. |
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Peroxisome proliferator-activated receptor-gamma activity is associated with renal microvasculature. |
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Am. J. Physiol. Renal Physiol. |
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[Prostaglandin D2: biosynthesis, biological properties and participation in bronchial asthma]. |
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Pol. Arch. Med. Wewn. |
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15-Deoxy-delta(12,14)-prostaglandin J(2) inhibits IL-10 and IL-12 production by macrophages. |
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Biochem. Biophys. Res. Commun. |
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Bacterial lipopolysaccharide activates HIV long terminal repeat through Toll-like receptor 4. |
2001 |
J. Immunol. |
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A cyclopentenone prostaglandin activates mesangial MAP kinase independently of PPARgamma. |
2001 |
Biochem. Biophys. Res. Commun. |
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Cyclooxygenase-2 inhibitory cerebrosides from phytolaccae radix. |
2001 |
Chem. Pharm. Bull. |
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A comparison of mediators released or generated by IFN-gamma-treated human mast cells following aggregation of Fc gamma RI or Fc epsilon RI. |
2001 |
J. Immunol. |
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Peroxisome proliferator--activated receptor gamma activators inhibit interleukin-1beta-induced nitric oxide and matrix metalloproteinase 13 production in human chondrocytes. |
2001 |
Arthritis Rheum. |
pmid:11263774
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T helper cell type 2 cytokines coordinately regulate immunoglobulin E-dependent cysteinyl leukotriene production by human cord blood-derived mast cells: profound induction of leukotriene C(4) synthase expression by interleukin 4. |
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J. Exp. Med. |
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Prostaglandin biosynthesis by fat body from true armyworms, Pseudaletia unipuncta. |
2001 |
Insect Biochem. Mol. Biol. |
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Albumin regulates induction of peroxisome proliferator-activated receptor-gamma (PPARgamma) by 15-deoxy-delta(12-14)-prostaglandin J(2) in vitro and may be an important regulator of PPARgamma function in vivo. |
2001 |
Endocrinology |
pmid:11159824
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Prostaglandin J(2) inhibition of mesangial cell iNOS expression. |
2001 |
Clin. Immunol. |
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Effects of 15-deoxy-delta(12,14) prostaglandin J(2) and interleukin-4 in Toll-like receptor-4-mutant glial cells. |
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Eur. J. Pharmacol. |
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Central interactions between angiotensin II and PGD(2) in the regulation of vasopressin and oxytocin secretion in dehydrated rats. |
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Brain Res. |
pmid:11166690
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Safety of a specific COX-2 inhibitor in aspirin-induced asthma. |
2001 |
Clin. Exp. Allergy |
pmid:11251623
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Cetirizine inhibits skin reactions but not mediator release in immediate and developing late-phase allergic cutaneous reactions. A double-blind, placebo-controlled study. |
2001 |
Clin. Exp. Allergy |
pmid:11591187
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Lipid peroxidation end products-responded induction of a preneoplastic marker enzyme glutathione S-transferase P-form (GST-P) in rat liver on admistration via the portal vein. |
2001 |
Mutat. Res. |
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Ceramide accelerates dephosphorylation of extracellular signal-regulated kinase 1/2 to decrease prostaglandin D(2) production in RBL-2H3 cells. |
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Arch. Biochem. Biophys. |
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Biphasic effects of 15-deoxy-delta(12,14)-prostaglandin J(2) on glutathione induction and apoptosis in human endothelial cells. |
2001 |
Arterioscler. Thromb. Vasc. Biol. |
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Role of cyclopentenone prostaglandins in rat carrageenin pleurisy. |
2001 |
FEBS Lett. |
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15-Deoxy-delta(12,14)-prostaglandin J2 is a negative regulator of macrophage functions. |
2001 |
Int. Immunopharmacol. |
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Akrishnan VR and Menon VP |
Potential role of antioxidants during ethanol-induced changes in the fatty acid composition and arachidonic acid metabolites in male Wistar rats. |
2001 |
Cell Biol. Toxicol. |
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PPARgamma ligands inhibit TNF-alpha-induced LOX-1 expression in cultured endothelial cells. |
2001 |
Biochem. Biophys. Res. Commun. |
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Mechanism of prostaglandin D(2)-stimulated heat shock protein 27 induction in osteoblasts. |
2001 |
Cell. Signal. |
pmid:11483406
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Role of peroxisome proliferator-activated receptor gamma and its ligands in non-neoplastic and neoplastic human urothelial cells. |
2001 |
Am. J. Pathol. |
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PPAR-gamma ligands inhibit growth of human esophageal adenocarcinoma cells through induction of apoptosis, cell cycle arrest and reduction of ornithine decarboxylase activity. |
2001 |
Int. J. Oncol. |
pmid:11494023
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Rovin BH et al. |
Cyclopentenone prostaglandins inhibit cytokine-induced nf-kappab activation and chemokine production by human mesangial cells. |
2001 |
J. Am. Soc. Nephrol. |
pmid:11461938
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15-Deoxy-Delta 12,14-prostaglandin J2 inhibition of NF-kappaB-DNA binding through covalent modification of the p50 subunit. |
2001 |
J. Biol. Chem. |
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15-Deoxy-delta12,14-PGJ2, but not troglitazone, modulates IL-1beta effects in human chondrocytes by inhibiting NF-kappaB and AP-1 activation pathways. |
2001 |
FEBS Lett. |
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Nishimura H et al. |
Acute effects of prostaglandin D2 to induce airflow obstruction and airway microvascular leakage in guinea pigs: role of thromboxane A2 receptors. |
2001 |
Prostaglandins Other Lipid Mediat. |
pmid:11519790
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Magnitude of peroxisome proliferator-activated receptor-gamma activation is associated with important and seemingly opposite biological responses in breast cancer cells. |
2001 |
J. Investig. Med. |
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Peroxisome proliferator-activated receptor gamma ligands differentially modulate muscle cell differentiation and MyoD gene expression via peroxisome proliferator-activated receptor gamma -dependent and -independent pathways. |
2001 |
J. Biol. Chem. |
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