| MeSH term | MeSH ID | Detail |
|---|---|---|
| Leukemia, Basophilic, Acute | D015471 | 9 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
| Astrocytoma | D001254 | 15 associated lipids |
| Carotid Artery Thrombosis | D002341 | 7 associated lipids |
| Nasal Polyps | D009298 | 26 associated lipids |
| Hypersensitivity, Immediate | D006969 | 14 associated lipids |
| Respiratory Hypersensitivity | D012130 | 18 associated lipids |
| Subarachnoid Hemorrhage | D013345 | 17 associated lipids |
| Leukemia, Experimental | D007942 | 42 associated lipids |
PGD2
Pgd2 is a lipid of Fatty Acyls (FA) class. Pgd2 is associated with abnormalities such as Inflammatory disorder, Pleurisy, Rhinitis, Dehydration and Pneumonia. The involved functions are known as antagonists, fat cell differentiation, Phosphorylation, Process and Gene Expression. Pgd2 often locates in Cell surface, Body tissue, Extracellular, Bone Marrow and Membrane. The associated genes with PGD2 are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, P4HTM gene, PTGS2 gene, PTGDS gene and IL3 gene. The related lipids are 15-deoxyprostaglandin J2, Nonesterified Fatty Acids, Lipopolysaccharides, Steroids and Liposomes. The related experimental models are Knock-out and Rodent Model.
Cross Reference
Introduction
To understand associated biological information of PGD2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PGD2?
PGD2 is suspected in Asthma, Dehydration, Allergic rhinitis NOS, Rhinitis, Infertility, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PGD2
PubChem Associated disorders and diseases
What pathways are associated with PGD2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PGD2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with PGD2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with PGD2?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with PGD2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PGD2?
Knock-out
Knock-out are used in the study 'Multiple roles of the prostaglandin D2 signaling pathway in reproduction.' (Rossitto M et al., 2015).
Rodent Model
Rodent Model are used in the study 'PKA regulatory IIα subunit is essential for PGD2-mediated resolution of inflammation.' (Kong D et al., 2016).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with PGD2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Tasaka K et al. | Prostaglandin D2 induces release of luteinizing hormone from the rat pituitary gland without the modulation of hypothalamic luteinizing hormone releasing hormone. | 1983 | J. Endocrinol. | pmid:6361197 |
| Horie H et al. | Modulation by prostaglandin D2 of glucagon and insulin secretion in the perfused rat pancreas. | 1983 | Prostaglandins Leukot Med | pmid:6361782 |
| Norman PS | The John Sheldon memorial lecture. Review of nasal therapy: update. | 1983 | J. Allergy Clin. Immunol. | pmid:6195204 |
| Feinstein MB et al. | The cytoplasmic concentration of free calcium in platelets is controlled by stimulators of cyclic AMP production (PGD2, PGE1, forskolin). | 1983 | Biochem. Biophys. Res. Commun. | pmid:6307295 |
| Watanabe Y et al. | Localization of prostaglandin D2 binding protein and NADP-linked 15-hydroxyprostaglandin D2 dehydrogenase in the Purkinje cells of miniature pig cerebellum. | 1983 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6308629 |
| Ishizawa M | Contractile effects of PGD2 and PGF2 alpha on mechanical and electrical activities in longitudinal and circular muscles of the guinea-pig colon. | 1983 | Prostaglandins | pmid:6580679 |
| Bregman MD and Meyskens FL | In vitro modulation of human and murine melanoma growth by prostanoid analogues. | 1983 | Prostaglandins | pmid:6581509 |
| Gaetani P et al. | [Prostaglandin D2 in subarachnoid hemorrhage. Biological and diagnostic implications]. | 1983 Jul-Aug | Riv Patol Nerv Ment | pmid:6598516 |
| Brus R et al. | Effect of prostaglandins on morphine-induced catalepsy in mice. | 1983 Sep-Dec | Acta Physiol Pol | pmid:6679984 |
| Rao PS et al. | Prostaglandin D2 in canine endotoxic shock. Hemodynamic, hematologic, biochemical, and blood gas analyses. | 1984 | Am. J. Obstet. Gynecol. | pmid:6424477 |
| Schick B et al. | Activation of rat serosal mast cells by chymase, an endogenous secretory granule protease. | 1984 | J. Immunol. | pmid:6425408 |
| Mitsuma T and Nogimori T | Effects of substance P, angiotensin II, oxotremorine and prostaglandin D2 on thyrotropin secretion in rats. | 1984 | Horm. Res. | pmid:6201427 |
| Ennis M et al. | Prostaglandin and histamine release from stimulated rat peritoneal mast cells. | 1984 | Agents Actions | pmid:6203356 |
| Inoué S et al. | Differential sleep-promoting effects of five sleep substances nocturnally infused in unrestrained rats. | 1984 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6592612 |
| Inoué S et al. | Little sleep-promoting effect of three sleep substances diurnally infused in unrestrained rats. | 1984 | Neurosci. Lett. | pmid:6593603 |
| Marsden KA et al. | The effect of prostaglandin D2 (PGD2) on circulating eosinophils. | 1984 | Prostaglandins Leukot Med | pmid:6593748 |
| Uemura S et al. | Inotropic effects of prostaglandin D2 and E1 on the newborn rabbit heart. | 1984 | Pediatr. Res. | pmid:6596550 |
| Kikawa Y et al. | 9-Deoxy-delta 9, delta 12-13,14-dihydroprostaglandin D2, a metabolite of prostaglandin D2 formed in human plasma. | 1984 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6584883 |
| Sakai T et al. | Prostaglandin D2 inhibits the proliferation of human malignant tumor cells. | 1984 | Prostaglandins | pmid:6584941 |
| Imashuku S et al. | [Differentiation induction and potentiation of chemotherapy by PGE1 infusion in patients with neuroblastoma--effect of PGE1 on metastatic potential of neuroblastoma]. | 1984 | Gan To Kagaku Ryoho | pmid:6585182 |