Yang G et al. |
Systemic PPARγ deletion impairs circadian rhythms of behavior and metabolism. |
2012 |
PLoS ONE |
pmid:22899986
|
Wang P et al. |
The antagonistic actions of endogenous interleukin-1β and 15-deoxy-Δ12,14-prostaglandin J2 regulate the temporal synthesis of matrix metalloproteinase-9 in sheared chondrocytes. |
2012 |
J. Biol. Chem. |
pmid:22829602
|
Nicholson JD et al. |
PGJ(2) provides prolonged CNS stroke protection by reducing white matter edema. |
2012 |
PLoS ONE |
pmid:23284631
|
Xiao L et al. |
Lipopolysaccharide-induced expression of microsomal prostaglandin E synthase-1 mediates late-phase PGE2 production in bone marrow derived macrophages. |
2012 |
PLoS ONE |
pmid:23226252
|
Alba G et al. |
Transcription of liver X receptor is down-regulated by 15-deoxy-Δ(12,14)-prostaglandin J(2) through oxidative stress in human neutrophils. |
2012 |
PLoS ONE |
pmid:23115616
|
Paulitschke V et al. |
Proteome analysis identified the PPARγ ligand 15d-PGJ2 as a novel drug inhibiting melanoma progression and interfering with tumor-stroma interaction. |
2012 |
PLoS ONE |
pmid:23049949
|
Syeda PK et al. |
A monoclonal antibody specific for Δ12-prostaglandin J2 and its utilization in the immunological assay in cell culture system of adipocytes. |
2012 |
Hybridoma (Larchmt) |
pmid:23098304
|
Weng Y et al. |
Prostaglandin metabolite induces inhibition of TRPA1 and channel-dependent nociception. |
2012 |
Mol Pain |
pmid:23013719
|
Maurer M and Church MK |
Inflammatory skin responses induced by icatibant injection are mast cell mediated and attenuated by H(1)-antihistamines. |
2012 |
Exp. Dermatol. |
pmid:22142018
|
Fujimori K et al. |
Prevention of paraquat-induced apoptosis in human neuronal SH-SY5Y cells by lipocalin-type prostaglandin D synthase. |
2012 |
J. Neurochem. |
pmid:22043816
|
Bardelli C et al. |
Autocrine activation of human monocyte/macrophages by monocyte-derived microparticles and modulation by PPARγ ligands. |
2012 |
Br. J. Pharmacol. |
pmid:21745193
|
Chae HS and Chin YW |
Anti-allergic effect of lambertianic acid from Thuja orientalis in mouse bone marrow-derived mast cells. |
2012 |
Immunopharmacol Immunotoxicol |
pmid:21854102
|
Miyawaki T et al. |
Combination of midazolam and a cyclooxygenase-2 inhibitor inhibits lipopolysaccharide-induced interleukin-6 production in human peripheral blood mononuclear cells. |
2012 |
Immunopharmacol Immunotoxicol |
pmid:21854184
|
Maicas N et al. |
Prostaglandin D2 regulates joint inflammation and destruction in murine collagen-induced arthritis. |
2012 |
Arthritis Rheum. |
pmid:21898357
|
Xue L et al. |
Leukotriene E4 activates human Th2 cells for exaggerated proinflammatory cytokine production in response to prostaglandin D2. |
2012 |
J. Immunol. |
pmid:22174450
|
He S et al. |
Identification, organ expression and ligand-dependent expression levels of peroxisome proliferator activated receptors in grass carp (Ctenopharyngodon idella). |
2012 |
Comp. Biochem. Physiol. C Toxicol. Pharmacol. |
pmid:22079418
|
Clemente-Napimoga JT et al. |
15d-PGJ2-loaded in nanocapsules enhance the antinociceptive properties into rat temporomandibular hypernociception. |
2012 |
Life Sci. |
pmid:22564409
|
Inceoglu AB et al. |
Inhibition of soluble epoxide hydrolase limits niacin-induced vasodilation in mice. |
2012 |
J. Cardiovasc. Pharmacol. |
pmid:22526297
|
Higashi N et al. |
Aspirin-intolerant asthma (AIA) assessment using the urinary biomarkers, leukotriene E4 (LTE4) and prostaglandin D2 (PGD2) metabolites. |
2012 |
Allergol Int |
pmid:22627848
|
Kristensen DM et al. |
Paracetamol (acetaminophen), aspirin (acetylsalicylic acid) and indomethacin are anti-androgenic in the rat foetal testis. |
2012 |
Int. J. Androl. |
pmid:22612476
|
Hogrefe C et al. |
Single impact cartilage trauma and TNF-α: interactive effects do not increase early cell death and indicate the need for bi-/multidirectional therapeutic approaches. |
2012 |
Int. J. Mol. Med. |
pmid:22922824
|
Lee E et al. |
15-Deoxy-Δ12,14-prostaglandin J₂ modulates manganese-induced activation of the NF-κB, Nrf2, and PI3K pathways in astrocytes. |
2012 |
Free Radic. Biol. Med. |
pmid:22245093
|
Lee S et al. |
Lipocalin-type prostaglandin D2 synthase protein regulates glial cell migration and morphology through myristoylated alanine-rich C-kinase substrate: prostaglandin D2-independent effects. |
2012 |
J. Biol. Chem. |
pmid:22275363
|
Ledwidge MT et al. |
In vivo impact of prodrug isosorbide-5-nicotinate-2-aspirinate on lipids and prostaglandin D2: is this a new immediate-release therapeutic option for niacin? |
2012 |
Atherosclerosis |
pmid:22326030
|
Baek K et al. |
Myeloid Elf-1-like factor stimulates adipogenic differentiation through the induction of peroxisome proliferator-activated receptor γ expression in bone marrow. |
2012 |
J. Cell. Physiol. |
pmid:22307523
|
MartÃnez AE et al. |
15-Deoxy-Δ(12,14)-prostaglandin J2 exerts pro- and anti-inflammatory effects in mesangial cells in a concentration-dependent manner. |
2012 |
Inflamm Allergy Drug Targets |
pmid:22309084
|
Fujita M et al. |
Cytotoxicity of 15-deoxy-Δ(12,14)-prostaglandin J(2) through PPARγ-independent pathway and the involvement of the JNK and Akt pathway in renal cell carcinoma. |
2012 |
Int J Med Sci |
pmid:22991494
|
Farnesi-de-Assunção TS et al. |
PPAR-γ agonists, mainly 15d-PGJ(2), reduce eosinophil recruitment following allergen challenge. |
2012 |
Cell. Immunol. |
pmid:22192475
|
Kuriyan AE et al. |
Electrophilic PPARγ ligands inhibit corneal fibroblast to myofibroblast differentiation in vitro: a potentially novel therapy for corneal scarring. |
2012 |
Exp. Eye Res. |
pmid:22178289
|
Yang K et al. |
[Changes of prostaglandin D2,carboxypeptidase A3 and platelet activating factor in guinea pig in anaphylactic shock]. |
2012 |
Fa Yi Xue Za Zhi |
pmid:22812216
|
Komoda T and Nishikawa M |
6'-Hydroxyoxosorbicillinol, a new lipoxygenase inhibitor and PGD2/LTB4 release suppressor from Penicillium sp. |
2012 |
Biosci. Biotechnol. Biochem. |
pmid:22785490
|
Joo M and Sadikot RT |
PGD synthase and PGD2 in immune resposne. |
2012 |
Mediators Inflamm. |
pmid:22791937
|
Baudouin-Legros M et al. |
Long-term CFTR inhibition modulates 15d-prostaglandin J2 in human pulmonary cells. |
2012 |
Int. J. Biochem. Cell Biol. |
pmid:22481026
|
Weng Z et al. |
Quercetin is more effective than cromolyn in blocking human mast cell cytokine release and inhibits contact dermatitis and photosensitivity in humans. |
2012 |
PLoS ONE |
pmid:22470478
|
Takahashi G et al. |
The potential role of prostaglandin D2 in nasal congestion observed in a guinea pig model of allergic rhinitis. |
2012 |
Int. Arch. Allergy Immunol. |
pmid:22472859
|
Abdo H et al. |
The omega-6 fatty acid derivative 15-deoxy-Δ¹²,¹â´-prostaglandin J2 is involved in neuroprotection by enteric glial cells against oxidative stress. |
2012 |
J. Physiol. (Lond.) |
pmid:22473776
|
Ji Y et al. |
Activation of rat intestinal mucosal mast cells by fat absorption. |
2012 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:22461027
|
Kim SE et al. |
15-deoxy-Δ¹²,¹ⴠ-prostaglandin J₂ inhibits human immunodeficiency virus-1 tat-induced monocyte chemoattractant protein-1/CCL2 production by blocking the extracellular signal-regulated kinase-1/2 signaling pathway independently of peroxisome proliferator-activated receptor-γ and heme oxygenase-1 in rat hippocampal slices. |
2012 |
J. Neurosci. Res. |
pmid:22487967
|
Garza LA et al. |
Prostaglandin D2 inhibits hair growth and is elevated in bald scalp of men with androgenetic alopecia. |
2012 |
Sci Transl Med |
pmid:22440736
|
Liu X et al. |
15-Deoxy-Δ(12,14)-prostaglandin J(2) attenuates the biological activities of monocyte/macrophage cell lines. |
2012 |
Eur. J. Cell Biol. |
pmid:22560326
|
Gross-Sondej I et al. |
[Measurement of bronchoconstrictive eicosanoids in chronic obstructive pulmonary disease]. |
2012 |
Pneumonol Alergol Pol |
pmid:22370980
|
Han Z et al. |
15-deoxy-Δ12,14 -prostaglandin J2 reduces recruitment of bone marrow-derived monocyte/macrophages in chronic liver injury in mice. |
2012 |
Hepatology |
pmid:22371273
|
Syeda PK et al. |
Generation of monoclonal antibody for 15-deoxy-Δ¹²,¹â´-prostaglandin Jâ‚‚ and development of enzyme-linked immunosorbent assay for its quantification in culture medium of adipocytes. |
2012 |
Appl. Biochem. Biotechnol. |
pmid:22391692
|
Quinteiro MS et al. |
The indirect antinociceptive mechanism of 15d-PGJ2 on rheumatoid arthritis-induced TMJ inflammatory pain in rats. |
2012 |
Eur J Pain |
pmid:22354681
|
Prage EB et al. |
Observation of two modes of inhibition of human microsomal prostaglandin E synthase 1 by the cyclopentenone 15-deoxy-Δ(12,14)-prostaglandin J(2). |
2012 |
Biochemistry |
pmid:22356188
|
Numazawa S et al. |
Possible involvement of transient receptor potential channels in electrophile-induced insulin secretion from RINm5F cells. |
2012 |
Biol. Pharm. Bull. |
pmid:22382320
|
Lin YC et al. |
The glutathionylation of p65 modulates NF-κB activity in 15-deoxy-Δ¹²,¹â´-prostaglandin Jâ‚‚-treated endothelial cells. |
2012 |
Free Radic. Biol. Med. |
pmid:22387200
|
Carsin A et al. |
[Physiopathology of aspirin intolerant asthma]. |
2012 |
Rev Mal Respir |
pmid:22405107
|
Song WL et al. |
Niacin and biosynthesis of PGDâ‚‚by platelet COX-1 in mice and humans. |
2012 |
J. Clin. Invest. |
pmid:22406532
|
Nagata N and Urade Y |
[Endogenous sleep-promoting substance]. |
2012 |
Nippon Rinsho |
pmid:22844810
|
Philipose S et al. |
Laropiprant attenuates EP3 and TP prostanoid receptor-mediated thrombus formation. |
2012 |
PLoS ONE |
pmid:22870195
|
Kim YI et al. |
Effects of 15-deoxy-∆¹²,¹â´-prostaglandin Jâ‚‚ on the production of IL-8 and the expression of Toll-like receptor 2 in human primary keratinocytes stimulated with lipopolysaccharide. |
2011 |
Mol. Biol. Rep. |
pmid:20174873
|
Mor A et al. |
Inhibitory effect of farnesylthiosalicylic acid on mediators release by mast cells: preferential inhibition of prostaglandin D(2) and tumor necrosis factor-α release. |
2011 |
Inflammation |
pmid:20706780
|
Balzar S et al. |
Mast cell phenotype, location, and activation in severe asthma. Data from the Severe Asthma Research Program. |
2011 |
Am. J. Respir. Crit. Care Med. |
pmid:20813890
|
Menon R et al. |
Amniotic fluid eicosanoids in preterm and term births: effects of risk factors for spontaneous preterm labor. |
2011 |
Obstet Gynecol |
pmid:21691170
|
Chowdhury AA et al. |
15-Deoxy-Δ(12,14)-prostaglandin J(2) interferes inducible synthesis of prostaglandins E(2) and F(2α) that suppress subsequent adipogenesis program in cultured preadipocytes. |
2011 |
Prostaglandins Other Lipid Mediat. |
pmid:21699992
|
Yamamoto Y et al. |
Dual functions of prostaglandin D2 in murine contact hypersensitivity via DP and CRTH2. |
2011 |
Am. J. Pathol. |
pmid:21703412
|
Ulivi V et al. |
Anti-inflammatory activity of monogalactosyldiacylglycerol in human articular cartilage in vitro: activation of an anti-inflammatory cyclooxygenase-2 (COX-2) pathway. |
2011 |
Arthritis Res. Ther. |
pmid:21682897
|
Farhat A et al. |
Hematopoietic-Prostaglandin D2 synthase through PGD2 production is involved in the adult ovarian physiology. |
2011 |
J Ovarian Res |
pmid:21352547
|
Yamamoto Y et al. |
15-Deoxy-Δ12,14-prostaglandin J2 enhanced the anti-tumor activity of camptothecin against renal cell carcinoma independently of topoisomerase-II and PPARγ pathways. |
2011 |
Biochem. Biophys. Res. Commun. |
pmid:21683069
|
Luker T et al. |
Zwitterionic CRTh2 antagonists. |
2011 |
J. Med. Chem. |
pmid:21355602
|
Ayoub SS et al. |
Cyclooxygenase expression and prostaglandin levels in central nervous system tissues during the course of chronic relapsing experimental autoimmune encephalomyelitis (EAE). |
2011 |
Inflamm. Res. |
pmid:21667309
|
Matsumoto T et al. |
Lipocalin-type prostaglandin D synthase is associated with coronary vasospasm and vasomotor reactivity in response to acetylcholine. |
2011 |
Circ. J. |
pmid:21325722
|
Cha B et al. |
15-deoxy-D12,14-prostaglandin J2 suppresses RANTES expression by inhibiting NADPH oxidase activation in Helicobacter pylori-infected gastric epithelial cells. |
2011 |
J. Physiol. Pharmacol. |
pmid:21673364
|
Wang P et al. |
Interleukin-6 synthesis in human chondrocytes is regulated via the antagonistic actions of prostaglandin (PG)E2 and 15-deoxy-Δ(12,14)-PGJ2. |
2011 |
PLoS ONE |
pmid:22096605
|
Maekawa N et al. |
High-performance affinity purification for identification of 15-deoxy-Δ 12,14 -PGJ₂ interacting factors using magnetic nanobeads. |
2011 |
Biomed. Chromatogr. |
pmid:21374648
|
Kane CJ et al. |
Protection of neurons and microglia against ethanol in a mouse model of fetal alcohol spectrum disorders by peroxisome proliferator-activated receptor-γ agonists. |
2011 |
Brain Behav. Immun. |
pmid:21376806
|
Arima M and Fukuda T |
Prostaglandin Dâ‚‚ and T(H)2 inflammation in the pathogenesis of bronchial asthma. |
2011 |
Korean J. Intern. Med. |
pmid:21437156
|
Luna-Gomes T et al. |
Eosinophils as a novel cell source of prostaglandin D2: autocrine role in allergic inflammation. |
2011 |
J. Immunol. |
pmid:22102725
|
MartÃnez-Gras I et al. |
The anti-inflammatory prostaglandin 15d-PGJ2 and its nuclear receptor PPARgamma are decreased in schizophrenia. |
2011 |
Schizophr. Res. |
pmid:21334179
|
Zhao J et al. |
Age-related increases in PGD(2) expression impair respiratory DC migration, resulting in diminished T cell responses upon respiratory virus infection in mice. |
2011 |
J. Clin. Invest. |
pmid:22105170
|
Chbicheb S et al. |
EGR1 expression: a calcium and ERK1/2 mediated PPARγ-independent event involved in the antiproliferative effect of 15-deoxy-Δ12,14-prostaglandin J2 and thiazolidinediones in breast cancer cells. |
2011 |
Biochem. Pharmacol. |
pmid:21338579
|
Braciale TJ and Kim TS |
Slowing down with age: lung DCs do it too. |
2011 |
J. Clin. Invest. |
pmid:22105176
|
Qiu Z et al. |
Cough reflex sensitivity and airway inflammation in patients with chronic cough due to non-acid gastro-oesophageal reflux. |
2011 |
Respirology |
pmid:21342332
|
Wang JJ and Mak OT |
Induction of apoptosis by 15d-PGJ2 via ROS formation: an alternative pathway without PPARγ activation in non-small cell lung carcinoma A549 cells. |
2011 |
Prostaglandins Other Lipid Mediat. |
pmid:21396480
|
Murata T et al. |
Prostagladin D2 is a mast cell-derived antiangiogenic factor in lung carcinoma. |
2011 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:22106279
|
Bräutigam K et al. |
Combined treatment with TRAIL and PPARγ ligands overcomes chemoresistance of ovarian cancer cell lines. |
2011 |
J. Cancer Res. Clin. Oncol. |
pmid:20878528
|
Alves C et al. |
Effects of 15d-PGJâ‚‚-loaded poly(D,L-lactide-co-glycolide) nanocapsules on inflammation. |
2011 |
Br. J. Pharmacol. |
pmid:20883476
|
Kanda N et al. |
The antimycotic drugs itraconazole and terbinafine hydrochloride induce the production of human β-defensin-3 in human keratinocytes. |
2011 |
Immunobiology |
pmid:20875690
|
Liu H et al. |
Modification of ubiquitin-C-terminal hydrolase-L1 by cyclopentenone prostaglandins exacerbates hypoxic injury. |
2011 |
Neurobiol. Dis. |
pmid:20933087
|
Moniot B et al. |
Hematopoietic prostaglandin D synthase (H-Pgds) is expressed in the early embryonic gonad and participates to the initial nuclear translocation of the SOX9 protein. |
2011 |
Dev. Dyn. |
pmid:21887724
|
Hewson CA et al. |
A differential role for ceramide kinase in antigen/FcɛRI-mediated mast cell activation and function. |
2011 |
Clin. Exp. Allergy |
pmid:21255156
|
Kanai Y et al. |
Identification of novel oxidized levuglandin D2 in marine red alga and mouse tissue. |
2011 |
J. Lipid Res. |
pmid:21893678
|
He P et al. |
Oxidative stress suppresses cysteinyl leukotriene generation by mouse bone marrow-derived mast cells. |
2011 |
J. Biol. Chem. |
pmid:21233206
|
Tao H and Hajri T |
Very low density lipoprotein receptor promotes adipocyte differentiation and mediates the proadipogenic effect of peroxisome proliferator-activated receptor gamma agonists. |
2011 |
Biochem. Pharmacol. |
pmid:21924248
|
Kitz K et al. |
15-Deoxy-Δ12,14-prostaglandin J2 induces Cox-2 expression in human osteosarcoma cells through MAPK and EGFR activation involving reactive oxygen species. |
2011 |
Free Radic. Biol. Med. |
pmid:21236332
|
Hossain MS et al. |
Development of enzyme-linked immunosorbent assay for Δ12-prostaglandin J2 and its application to the measurement of the endogenous product generated by cultured adipocytes during the maturation phase. |
2011 |
Prostaglandins Other Lipid Mediat. |
pmid:21237281
|
De Nuccio C et al. |
Peroxisome proliferator-activated receptor γ agonists accelerate oligodendrocyte maturation and influence mitochondrial functions and oscillatory Ca(2+) waves. |
2011 |
J. Neuropathol. Exp. Neurol. |
pmid:21937914
|
Choi YH et al. |
The extracellular signal-regulated kinase mitogen-activated protein kinase/ribosomal S6 protein kinase 1 cascade phosphorylates cAMP response element-binding protein to induce MUC5B gene expression via D-prostanoid receptor signaling. |
2011 |
J. Biol. Chem. |
pmid:21832046
|
Aung G et al. |
Catestatin, a neuroendocrine antimicrobial peptide, induces human mast cell migration, degranulation and production of cytokines and chemokines. |
2011 |
Immunology |
pmid:21214543
|
Chowdhury AA et al. |
Sustained expression of lipocalin-type prostaglandin D synthase in the antisense direction positively regulates adipogenesis in cloned cultured preadipocytes. |
2011 |
Biochem. Biophys. Res. Commun. |
pmid:21726533
|
Hovsepian E et al. |
Modulation of inflammatory response and parasitism by 15-Deoxy-Δ(12,14) prostaglandin J(2) in Trypanosoma cruzi-infected cardiomyocytes. |
2011 |
Int. J. Parasitol. |
pmid:21215746
|
Song NY et al. |
Multidrug resistance-associated protein 1 mediates 15-deoxy-Δ(12,14)-prostaglandin J2-induced expression of glutamate cysteine ligase expression via Nrf2 signaling in human breast cancer cells. |
2011 |
Chem. Res. Toxicol. |
pmid:21728338
|
Lotz C et al. |
Activation of peroxisome-proliferator-activated receptors α and γ mediates remote ischemic preconditioning against myocardial infarction in vivo. |
2011 |
Exp. Biol. Med. (Maywood) |
pmid:21163821
|
Charles RL et al. |
Redox regulation of soluble epoxide hydrolase by 15-deoxy-delta-prostaglandin J2 controls coronary hypoxic vasodilation. |
2011 |
Circ. Res. |
pmid:21164107
|
Cichocka-Jarosz E et al. |
Serum tryptase level is a better predictor of systemic side effects than prostaglandin D2 metabolites during venom immunotherapy in children. |
2011 |
J Investig Allergol Clin Immunol |
pmid:21721371
|
Wang P et al. |
Response of chondrocytes to shear stress: antagonistic effects of the binding partners Toll-like receptor 4 and caveolin-1. |
2011 |
FASEB J. |
pmid:21715681
|
Ahmed SR et al. |
Prostaglandin D2 regulates CD4+ memory T cell trafficking across blood vascular endothelium and primes these cells for clearance across lymphatic endothelium. |
2011 |
J. Immunol. |
pmid:21715691
|
Yu R et al. |
Competitive enzymatic interactions determine the relative amounts of prostaglandins E2 and D2. |
2011 |
J. Pharmacol. Exp. Ther. |
pmid:21865441
|
Koyama J et al. |
Simultaneous determination of histamine and prostaglandin D2 using an LC-ESI-MS/MS method with positive/negative ion-switching ionization modes: application to the study of anti-allergic flavonoids on the degranulation of KU812 cells. |
2011 |
Anal Bioanal Chem |
pmid:21725829
|