PGD2

Pgd2 is a lipid of Fatty Acyls (FA) class. Pgd2 is associated with abnormalities such as Inflammatory disorder, Pleurisy, Rhinitis, Dehydration and Pneumonia. The involved functions are known as antagonists, fat cell differentiation, Phosphorylation, Process and Gene Expression. Pgd2 often locates in Cell surface, Body tissue, Extracellular, Bone Marrow and Membrane. The associated genes with PGD2 are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, P4HTM gene, PTGS2 gene, PTGDS gene and IL3 gene. The related lipids are 15-deoxyprostaglandin J2, Nonesterified Fatty Acids, Lipopolysaccharides, Steroids and Liposomes. The related experimental models are Knock-out and Rodent Model.

Cross Reference

Introduction

To understand associated biological information of PGD2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with PGD2?

PGD2 is suspected in Asthma, Dehydration, Allergic rhinitis NOS, Rhinitis, Infertility, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with PGD2

MeSH term MeSH ID Detail
Actinobacillus Infections D000189 4 associated lipids
Adenocarcinoma D000230 166 associated lipids
Alzheimer Disease D000544 76 associated lipids
Anal Gland Neoplasms D000694 1 associated lipids
Anaphylaxis D000707 35 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Arteriosclerosis D001161 86 associated lipids
Arthritis D001168 41 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Ascariasis D001196 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with PGD2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with PGD2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with PGD2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with PGD2?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with PGD2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with PGD2?

Knock-out

Knock-out are used in the study 'Multiple roles of the prostaglandin D2 signaling pathway in reproduction.' (Rossitto M et al., 2015).

Rodent Model

Rodent Model are used in the study 'PKA regulatory IIα subunit is essential for PGD2-mediated resolution of inflammation.' (Kong D et al., 2016).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with PGD2

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Per page 10 20 50 100 | Total 3138
Authors Title Published Journal PubMed Link
Odani N et al. Regulation of BiP gene expression by cyclopentenone prostaglandins through unfolded protein response element. 1996 J. Biol. Chem. pmid:8663202
Kawamoto K [Flow cytometric analysis of cell cycle for the action mechanism of antineoplastic agents]. 1995 Hum. Cell pmid:8652450
Satoh S et al. Promotion of sleep mediated by the A2a-adenosine receptor and possible involvement of this receptor in the sleep induced by prostaglandin D2 in rats. 1996 Proc. Natl. Acad. Sci. U.S.A. pmid:8650205
Weidenbach H et al. Reduction of bile secretion by prostaglandins in the rat in vivo. 1996 Life Sci. pmid:8649182
Genovese A et al. Role of mast cells, basophils and their mediators in adverse reactions to general anesthetics and radiocontrast media. 1996 Int. Arch. Allergy Immunol. pmid:8645973
Odani N et al. Induction of protein disulfide isomerase mRNA by delta 12-prostaglandin J2. 1996 Biochem. Biophys. Res. Commun. pmid:8645293
Chilton FH et al. Antigen-induced generation of lyso-phospholipids in human airways. 1996 J. Exp. Med. pmid:8642333
Longphre M et al. PAF-induced airways hyperreactivity is modulated by mast cells in mice. 1996 Am. J. Respir. Cell Mol. Biol. pmid:8624251
Seghaye MC et al. Histamine liberation related to cardiopulmonary bypass in children: possible relation to transient postoperative arrhythmias. 1996 J. Thorac. Cardiovasc. Surg. pmid:8622322
Rozera C et al. Inhibition of HIV-1 replication by cyclopentenone prostaglandins in acutely infected human cells. Evidence for a transcriptional block. 1996 J. Clin. Invest. pmid:8621762