PGA1

Pga1 is a lipid of Fatty Acyls (FA) class. Pga1 is associated with abnormalities such as Hyperostosis, Diffuse Idiopathic Skeletal, Polyglandular Type I Autoimmune Syndrome and Infection. The involved functions are known as Uptake, inhibitors, Binding (Molecular Function), Denaturation and Adjudication. Pga1 often locates in Extracellular, Plasma membrane, Cytoplasmic, Cytoplasm and Retrobulbar. The associated genes with PGA1 are AIRE gene, synthetic peptide and Recombinant Proteins.

Cross Reference

Introduction

To understand associated biological information of PGA1, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with PGA1?

PGA1 is suspected in Infection, Polyglandular Type I Autoimmune Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with PGA1

MeSH term MeSH ID Detail
Inflammation D007249 119 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Body Weight D001835 333 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Glioma D005910 112 associated lipids
Leukemia P388 D007941 43 associated lipids
Brain Infarction D020520 17 associated lipids
Infarction, Middle Cerebral Artery D020244 35 associated lipids
Brain Ischemia D002545 89 associated lipids
Nerve Degeneration D009410 53 associated lipids
Per page 10 20 | Total 12

PubChem Associated disorders and diseases

What pathways are associated with PGA1

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with PGA1?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with PGA1?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with PGA1?

There are no associated biomedical information in the current reference collection.

What genes are associated with PGA1?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with PGA1?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with PGA1

Download all related citations
Per page 10 20 50 100 | Total 191
Authors Title Published Journal PubMed Link
Anta B et al. PGA1-induced apoptosis involves specific activation of H-Ras and N-Ras in cellular endomembranes. 2016 Cell Death Dis pmid:27468687
Díez-Dacal B et al. Molecular Interactions and Implications of Aldose Reductase Inhibition by PGA1 and Clinically Used Prostaglandins. 2016 Mol. Pharmacol. pmid:26487510
IsaÄ­ SV et al. [An example of oscillatory (cyclic) reaction for prostaglandin chemistry]. 2013 Jan-Feb Biomed Khim pmid:23650728
Stotz HU et al. TGA transcription factors and jasmonate-independent COI1 signalling regulate specific plant responses to reactive oxylipins. 2013 J. Exp. Bot. pmid:23349138
Hayashi Y and Umemiya S Pot economy in the synthesis of prostaglandin A1 and E1 methyl esters. 2013 Angew. Chem. Int. Ed. Engl. pmid:23404945
Sugiyama R et al. Induction of heat-shock protein 70 by prostaglandin A₁ inhibits HIV-1 Vif-mediated degradation of APOBEC3G. 2013 Antiviral Res. pmid:23831493
Díez-Dacal B and Pérez-Sala D A-class prostaglandins: early findings and new perspectives for overcoming tumor chemoresistance. 2012 Cancer Lett. pmid:22407242
Brunhofer G et al. Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine. 2012 Bioorg. Med. Chem. pmid:23062825
Díez-Dacal B et al. Identification of aldo-keto reductase AKR1B10 as a selective target for modification and inhibition by prostaglandin A(1): implications for antitumoral activity. 2011 Cancer Res. pmid:21507934
Garzón B et al. A biotinylated analog of the anti-proliferative prostaglandin A1 allows assessment of PPAR-independent effects and identification of novel cellular targets for covalent modification. 2010 Chem. Biol. Interact. pmid:19800325