Delta-12-prostaglandin j2

Delta-12-prostaglandin j2 is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 184 references associated with Delta-12-prostaglandin j2 in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Delta-12-prostaglandin j2

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Delta-12-prostaglandin j2

MeSH term MeSH ID Detail
Osteosarcoma D012516 50 associated lipids
Dehydration D003681 11 associated lipids
Total 2

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Delta-12-prostaglandin j2

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Authors Title Published Journal PubMed Link
Liu H et al. Prostaglandin D2 toxicity in primary neurons is mediated through its bioactive cyclopentenone metabolites. 2013 Neurotoxicology pmid:23973622
Ravindra KC et al. Targeting of histone acetyltransferase p300 by cyclopentenone prostaglandin Δ(12)-PGJ(2) through covalent binding to Cys(1438). 2012 Chem. Res. Toxicol. pmid:22141352
Neuhofer W et al. Chronic COX-2 inhibition reduces medullary HSP70 expression and induces papillary apoptosis in dehydrated rats. 2004 Kidney Int. pmid:14717913
Heinemann A et al. Delta 12-prostaglandin J2, a plasma metabolite of prostaglandin D2, causes eosinophil mobilization from the bone marrow and primes eosinophils for chemotaxis. 2003 J. Immunol. pmid:12707356
Hata AN et al. Expression and molecular pharmacology of the mouse CRTH2 receptor. 2003 J. Pharmacol. Exp. Ther. pmid:12721327
Ward C et al. Prostaglandin D2 and its metabolites induce caspase-dependent granulocyte apoptosis that is mediated via inhibition of I kappa B alpha degradation using a peroxisome proliferator-activated receptor-gamma-independent mechanism. 2002 J. Immunol. pmid:12055237
Sawyer N et al. Molecular pharmacology of the human prostaglandin D2 receptor, CRTH2. 2002 Br. J. Pharmacol. pmid:12466225
Pica F et al. Delta(12)-prostaglandin J(2) is a potent inhibitor of influenza A virus replication. 2000 Antimicrob. Agents Chemother. pmid:10602750
Marvin KW et al. The 15-deoxy-delta(12,14)-prostaglandin J(2)receptor, peroxisome proliferator activated receptor-gamma (PPARgamma) is expressed in human gestational tissues and is functionally active in JEG3 choriocarcinoma cells. 2000 Placenta pmid:10833383
Hamel L et al. Induction of heat shock protein 70 by herbimycin A and cyclopentenone prostaglandins in smooth muscle cells. 2000 Cell Stress Chaperones pmid:11147963