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Peroxisome proliferated-activated receptor gamma ligand, Pioglitazone, does not prevent hepatic fibrosis in mice. |
2007 |
Int. J. Mol. Med. |
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Targeting 15d-prostaglandin J2 to hepatic stellate cells: two options evaluated. |
2007 |
Pharm. Res. |
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Activation of peroxisome proliferator-activated receptor gamma contributes to the survival of T lymphoma cells by affecting cellular metabolism. |
2007 |
Am. J. Pathol. |
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[Effect of peroxisome proliferators-activated receptor-gamma in the mechanisms of sulindac against large intestine carcinoma]. |
2007 |
Beijing Da Xue Xue Bao |
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Hasegawa H et al. |
A novel natural compound, a cycloanthranilylproline derivative (Fuligocandin B), sensitizes leukemia cells to apoptosis induced by tumor necrosis factor related apoptosis-inducing ligand (TRAIL) through 15-deoxy-Delta 12, 14 prostaglandin J2 production. |
2007 |
Blood |
pmid:17551094
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Engdahl R et al. |
15-Deoxy-Delta12,14-prostaglandin J2 (15d-PGJ2) mediates repression of TNF-alpha by decreasing levels of acetylated histone H3 and H4 at its promoter. |
2007 |
Biochem. Biophys. Res. Commun. |
pmid:17532302
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Monroy MA et al. |
THE PPARgamma ligand 15d-PGJ2 modulates macrophage activation after injury in a murine trauma model. |
2007 |
Shock |
pmid:17510607
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Zingarelli B et al. |
Diverse cardioprotective signaling mechanisms of peroxisome proliferator-activated receptor-gamma ligands, 15-deoxy-Delta12,14-prostaglandin J2 and ciglitazone, in reperfusion injury: role of nuclear factor-kappaB, heat shock factor 1, and Akt. |
2007 |
Shock |
pmid:17589386
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Ponferrada A et al. |
The role of PPARgamma on restoration of colonic homeostasis after experimental stress-induced inflammation and dysfunction. |
2007 |
Gastroenterology |
pmid:17484875
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Cerbone A et al. |
4-Hydroxynonenal and PPARgamma ligands affect proliferation, differentiation, and apoptosis in colon cancer cells. |
2007 |
Free Radic. Biol. Med. |
pmid:17462534
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Yano M et al. |
Statins activate peroxisome proliferator-activated receptor gamma through extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase-dependent cyclooxygenase-2 expression in macrophages. |
2007 |
Circ. Res. |
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Berry A et al. |
IL-13 induces expression of CD36 in human monocytes through PPARgamma activation. |
2007 |
Eur. J. Immunol. |
pmid:17458857
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Lim HJ et al. |
15d-PGJ2 stimulates HO-1 expression through p38 MAP kinase and Nrf-2 pathway in rat vascular smooth muscle cells. |
2007 |
Toxicol. Appl. Pharmacol. |
pmid:17631927
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15d-PGJ2 induces apoptosis of mouse oligodendrocyte precursor cells. |
2007 |
J Neuroinflammation |
pmid:17634127
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Ye Y et al. |
Activation of peroxisome proliferator-activated receptor-gamma (PPAR-gamma) by atorvastatin is mediated by 15-deoxy-delta-12,14-PGJ2. |
2007 |
Prostaglandins Other Lipid Mediat. |
pmid:17643887
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Desmarais JA et al. |
The peroxisome proliferator-activated receptor gamma regulates trophoblast cell differentiation in mink (Mustela vison). |
2007 |
Biol. Reprod. |
pmid:17615406
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Kaplan J et al. |
Peroxisome proliferator-activated receptor gamma is required for the inhibitory effect of ciglitazone but not 15-deoxy-Delta 12,14-prostaglandin J2 on the NFkappaB pathway in human endothelial cells. |
2007 |
Shock |
pmid:17621259
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Lin TH et al. |
PPARgamma inhibits osteogenesis via the down-regulation of the expression of COX-2 and iNOS in rats. |
2007 |
Bone |
pmid:17669705
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Schlezinger JJ et al. |
An L-tyrosine derivative and PPARgamma agonist, GW7845, activates a multifaceted caspase cascade in bone marrow B cells. |
2007 |
Toxicol. Sci. |
pmid:17400580
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Kim KY et al. |
Apoptotic action of peroxisome proliferator-activated receptor-gamma activation in human non small-cell lung cancer is mediated via proline oxidase-induced reactive oxygen species formation. |
2007 |
Mol. Pharmacol. |
pmid:17535976
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Cao LQ et al. |
[15-deoxy-Delta(12,14)-prostaglandin J(2) induces anoikis of hepatocellular carcinoma cells: an in vitro experiment]. |
2007 |
Zhonghua Yi Xue Za Zhi |
pmid:18261336
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Moon Y et al. |
Hypo-responsiveness of interleukin-8 production in human embryonic epithelial intestine 407 cells independent of NF-kappaB pathway: new lessons from endotoxin and ribotoxic deoxynivalenol. |
2008 |
Toxicol. Appl. Pharmacol. |
pmid:18485432
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Copple IM et al. |
The hepatotoxic metabolite of acetaminophen directly activates the Keap1-Nrf2 cell defense system. |
2008 |
Hepatology |
pmid:18785192
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Poncin S et al. |
Oxidative stress in the thyroid gland: from harmlessness to hazard depending on the iodine content. |
2008 |
Endocrinology |
pmid:17884933
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Caito S et al. |
Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2, PPARgamma agonists, differentially regulate cigarette smoke-mediated pro-inflammatory cytokine release in monocytes/macrophages. |
2008 |
Antioxid. Redox Signal. |
pmid:17970647
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Panzer U et al. |
15-deoxy-Delta12,14-prostaglandin J2 inhibits INF-gamma-induced JAK/STAT1 signalling pathway activation and IP-10/CXCL10 expression in mesangial cells. |
2008 |
Nephrol. Dial. Transplant. |
pmid:18596134
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Kim HY et al. |
Upregulation of lipopolysaccharide-induced interleukin-10 by prostaglandin A1 in mouse peritoneal macrophages. |
2008 |
J. Microbiol. Biotechnol. |
pmid:18600064
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Cruz-Orengo L et al. |
Cutaneous nociception evoked by 15-delta PGJ2 via activation of ion channel TRPA1. |
2008 |
Mol Pain |
pmid:18671867
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Oku H and Umino T |
Molecular characterization of peroxisome proliferator-activated receptors (PPARs) and their gene expression in the differentiating adipocytes of red sea bream Pagrus major. |
2008 |
Comp. Biochem. Physiol. B, Biochem. Mol. Biol. |
pmid:18691667
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Ryan AJ et al. |
15-deoxy-Delta12,14-prostaglandin J2 impairs phosphatidylcholine synthesis and induces nuclear accumulation of thiol-modified cytidylyltransferase. |
2008 |
J. Biol. Chem. |
pmid:18614529
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Ulivi V et al. |
15-deoxy-delta 12,14-prostaglandin J(2) inhibits the synthesis of the acute phase protein SIP24 in cartilage: Involvement of COX-2 in resolution of inflammation. |
2008 |
J. Cell. Physiol. |
pmid:18615580
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Genovese T et al. |
Effect of cyclopentanone prostaglandin 15-deoxy-delta12,14PGJ2 on early functional recovery from experimental spinal cord injury. |
2008 |
Shock |
pmid:18628687
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Bissonnette SL et al. |
An endogenous prostaglandin enhances environmental phthalate-induced apoptosis in bone marrow B cells: activation of distinct but overlapping pathways. |
2008 |
J. Immunol. |
pmid:18641309
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Qiao L et al. |
Down-regulation of X-linked inhibitor of apoptosis synergistically enhanced peroxisome proliferator-activated receptor gamma ligand-induced growth inhibition in colon cancer. |
2008 |
Mol. Cancer Ther. |
pmid:18645029
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Capobianco E et al. |
Effects of natural ligands of PPARgamma on lipid metabolism in placental tissues from healthy and diabetic rats. |
2008 |
Mol. Hum. Reprod. |
pmid:18621767
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Tonge D et al. |
Enhancement of axonal regeneration by in vitro conditioning and its inhibition by cyclopentenone prostaglandins. |
2008 |
J. Cell. Sci. |
pmid:18650498
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Niemoeller OM et al. |
Ciglitazone and 15d-PGJ2 induced suicidal erythrocyte death. |
2008 |
Cell. Physiol. Biochem. |
pmid:18769050
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Ho TC et al. |
15-deoxy-Delta(12,14)-prostaglandin J2 induces vascular endothelial cell apoptosis through the sequential activation of MAPKS and p53. |
2008 |
J. Biol. Chem. |
pmid:18718914
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Chearwae W and Bright JJ |
PPARgamma agonists inhibit growth and expansion of CD133+ brain tumour stem cells. |
2008 |
Br. J. Cancer |
pmid:19018263
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Lian TW et al. |
Fisetin, morin and myricetin attenuate CD36 expression and oxLDL uptake in U937-derived macrophages. |
2008 |
Biochim. Biophys. Acta |
pmid:18662803
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Jozkowicz A et al. |
15d-PGJ2 upregulates synthesis of IL-8 in endothelial cells through induction of oxidative stress. |
2008 |
Antioxid. Redox Signal. |
pmid:18665800
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Napimoga MH et al. |
Peroxisome proliferator-activated receptor-gamma ligand, 15-deoxy-Delta12,14-prostaglandin J2, reduces neutrophil migration via a nitric oxide pathway. |
2008 |
J. Immunol. |
pmid:18097063
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Dubourdeau M et al. |
Opposite roles of STAT and PPARgamma in the induction of p21WAF1 expression by IL-13 in human peripheral blood monocytes. |
2008 |
Eur. Cytokine Netw. |
pmid:19103521
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GarcÃa-Bueno B et al. |
Stress mediators regulate brain prostaglandin synthesis and peroxisome proliferator-activated receptor-gamma activation after stress in rats. |
2008 |
Endocrinology |
pmid:18079203
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Ferreira-Silva V et al. |
Effects of 15-deoxy-Delta12, 14 prostaglandin J2 and ciglitazone on human cancer cell cycle progression and death: the role of PPARgamma. |
2008 |
Eur. J. Pharmacol. |
pmid:18054911
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Zhang J et al. |
Peroxisome proliferator-activated receptor-gamma agonists attenuate angiotensin II-induced collagen type I expression in adventitial fibroblasts. |
2008 |
Clin. Exp. Pharmacol. Physiol. |
pmid:18047631
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Uchida K and Shibata T |
15-Deoxy-Delta(12,14)-prostaglandin J2: an electrophilic trigger of cellular responses. |
2008 |
Chem. Res. Toxicol. |
pmid:18052108
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Yu JH et al. |
SOCS 3 and PPAR-gamma ligands inhibit the expression of IL-6 and TGF-beta1 by regulating JAK2/STAT3 signaling in pancreas. |
2008 |
Int. J. Biochem. Cell Biol. |
pmid:18035585
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Kuboki S et al. |
Peroxisome proliferator-activated receptor-gamma protects against hepatic ischemia/reperfusion injury in mice. |
2008 |
Hepatology |
pmid:18085707
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Choi IK et al. |
PPAR-gamma ligand promotes the growth of APC-mutated HT-29 human colon cancer cells in vitro and in vivo. |
2008 |
Invest New Drugs |
pmid:18161004
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