Rodrigues WF et al. |
15d-PGJ(2) modulates acute immune responses to Trypanosoma cruzi infection. |
2010 |
Mem. Inst. Oswaldo Cruz |
pmid:20428671
|
Watanabe K et al. |
15-deoxy-delta 12,14-prostaglandin J2 prevents inflammatory response and endothelial cell damage in rats with acute obstructive cholangitis. |
2010 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:20056897
|
Hatanaka M et al. |
15d-prostaglandin J2 enhancement of nerve growth factor-induced neurite outgrowth is blocked by the chemoattractant receptor- homologous molecule expressed on T-helper type 2 cells (CRTH2) antagonist CAY10471 in PC12 cells. |
2010 |
J. Pharmacol. Sci. |
pmid:20424389
|
Zorrilla S et al. |
Selective binding of the fluorescent dye 1-anilinonaphthalene-8-sulfonic acid to peroxisome proliferator-activated receptor gamma allows ligand identification and characterization. |
2010 |
Anal. Biochem. |
pmid:20025845
|
Koyama M et al. |
Histone deacetylase inhibitors and 15-deoxy-Delta12,14-prostaglandin J2 synergistically induce apoptosis. |
2010 |
Clin. Cancer Res. |
pmid:20371690
|
Lin TH et al. |
Upregulation of heme oxygenase-1 inhibits the maturation and mineralization of osteoblasts. |
2010 |
J. Cell. Physiol. |
pmid:20020468
|
Hayden RE et al. |
Treatment of primary CLL cells with bezafibrate and medroxyprogesterone acetate induces apoptosis and represses the pro-proliferative signal of CD40-ligand, in part through increased 15dDelta12,14,PGJ2. |
2009 |
Leukemia |
pmid:18923439
|
Ricart KC et al. |
The permissive role of mitochondria in the induction of haem oxygenase-1 in endothelial cells. |
2009 |
Biochem. J. |
pmid:19161347
|
Lee DR et al. |
15-Deoxy-Delta(12,14)-prostaglandin J(2) induces mitochondrial-dependent apoptosis through inhibition of PKA/NF-kappaB in renal proximal epithelial cells. |
2009 |
Toxicology |
pmid:19167456
|
Liu J et al. |
Peroxisome proliferator-activated receptor-gamma ligands 15-deoxy-delta(12,14)-prostaglandin J2 and pioglitazone inhibit hydroxyl peroxide-induced TNF-alpha and lipopolysaccharide-induced CXC chemokine expression in neonatal rat cardiac myocytes. |
2009 |
Shock |
pmid:19174742
|
Pirianov G et al. |
The cyclopentenone 15-deoxy-delta 12,14-prostaglandin J(2) delays lipopolysaccharide-induced preterm delivery and reduces mortality in the newborn mouse. |
2009 |
Endocrinology |
pmid:18845626
|
Tsuji T et al. |
Reduction of nuclear peroxisome proliferator-activated receptor gamma expression in methamphetamine-induced neurotoxicity and neuroprotective effects of ibuprofen. |
2009 |
Neurochem. Res. |
pmid:18946735
|
Waku T et al. |
Structural insight into PPARgamma activation through covalent modification with endogenous fatty acids. |
2009 |
J. Mol. Biol. |
pmid:18977231
|
Tsutsui C et al. |
Peperomins as anti-inflammatory agents that inhibit the NF-kappaB signaling pathway. |
2009 |
Bioorg. Med. Chem. Lett. |
pmid:19559609
|
Bruck R et al. |
Additive inhibitory effect of experimentally induced hepatic cirrhosis by agonists of peroxisome proliferator activator receptor gamma and retinoic acid receptor. |
2009 |
Dig. Dis. Sci. |
pmid:18594976
|
O'Brien JJ et al. |
15-deoxy-Delta12,14 prostaglandin J2-induced heme oxygenase-1 in megakaryocytes regulates thrombopoiesis. |
2009 |
J. Thromb. Haemost. |
pmid:18983509
|
Kalantari P et al. |
15-Deoxy-Delta12,14-prostaglandin J2 inhibits HIV-1 transactivating protein, Tat, through covalent modification. |
2009 |
FASEB J. |
pmid:19299483
|
Moriai M et al. |
Down-regulation of hTERT expression plays an important role in 15-deoxy-Delta12,14-prostaglandin J2-induced apoptosis in cancer cells. |
2009 |
Int. J. Oncol. |
pmid:19360348
|
Iinuma K et al. |
Involvement of Propionibacterium acnes in the augmentation of lipogenesis in hamster sebaceous glands in vivo and in vitro. |
2009 |
J. Invest. Dermatol. |
pmid:19282842
|
Ferguson HE et al. |
Electrophilic peroxisome proliferator-activated receptor-gamma ligands have potent antifibrotic effects in human lung fibroblasts. |
2009 |
Am. J. Respir. Cell Mol. Biol. |
pmid:19286977
|
Shin SW et al. |
15d-PGJ2 induces apoptosis by reactive oxygen species-mediated inactivation of Akt in leukemia and colorectal cancer cells and shows in vivo antitumor activity. |
2009 |
Clin. Cancer Res. |
pmid:19690198
|
Ferguson HE et al. |
Peroxisome proliferator-activated receptor-gamma ligands induce heme oxygenase-1 in lung fibroblasts by a PPARgamma-independent, glutathione-dependent mechanism. |
2009 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:19734319
|
Kim DH et al. |
Effects of 15-deoxy-delta 12, 14-prostaglandin J2 on the expression of p53 in MCF-7 cells. |
2009 |
Ann. N. Y. Acad. Sci. |
pmid:19723057
|
Song NY et al. |
15-Deoxy-delta 12, 14-prostaglandin J2 induces upregulation of multidrug resistance-associated protein 1 via Nrf2 activation in human breast cancer cells. |
2009 |
Ann. N. Y. Acad. Sci. |
pmid:19723058
|
Cha B et al. |
15-Deoxy-delta 12, 14,-prostaglandin J2 suppresses nuclear factor-kappaB-mediated apoptosis of Helicobacter pylori-infected gastric epithelial cells. |
2009 |
Ann. N. Y. Acad. Sci. |
pmid:19723089
|
Ma XM et al. |
Peroxisome proliferator-activated receptor-gamma is essential in the pathogenesis of gastric carcinoma. |
2009 |
World J. Gastroenterol. |
pmid:19701967
|
Ding Q et al. |
Identification of macrophage inhibitory cytokine-1 in adipose tissue and its secretion as an adipokine by human adipocytes. |
2009 |
Endocrinology |
pmid:19074584
|
Gressner OA et al. |
Elevated concentrations of 15-deoxy-Delta12,14-prostaglandin J2 in chronic liver disease propose therapeutic trials with peroxisome proliferator activated receptor gamma-inducing drugs. |
2009 |
Liver Int. |
pmid:19018984
|
Kobayashi M et al. |
The antioxidant defense system Keap1-Nrf2 comprises a multiple sensing mechanism for responding to a wide range of chemical compounds. |
2009 |
Mol. Cell. Biol. |
pmid:19001094
|
Kim DH et al. |
15-Deoxy-Delta12,14-prostaglandin J2 upregulates the expression of heme oxygenase-1 and subsequently matrix metalloproteinase-1 in human breast cancer cells: possible roles of iron and ROS. |
2009 |
Carcinogenesis |
pmid:19136476
|
Wang WM et al. |
PPAR-gamma agonists inhibit TGF-beta1-induced chemokine expression in human tubular epithelial cells. |
2009 |
Acta Pharmacol. Sin. |
pmid:19098936
|
Waku T et al. |
Atomic structure of mutant PPARgamma LBD complexed with 15d-PGJ2: novel modulation mechanism of PPARgamma/RXRalpha function by covalently bound ligands. |
2009 |
FEBS Lett. |
pmid:19101554
|
Dong YW et al. |
Suppression of pancreatic carcinoma growth by activating peroxisome proliferator-activated receptor gamma involves angiogenesis inhibition. |
2009 |
World J. Gastroenterol. |
pmid:19152448
|
Baregamian N et al. |
PPAR-gamma agonist protects against intestinal injury during necrotizing enterocolitis. |
2009 |
Biochem. Biophys. Res. Commun. |
pmid:19114032
|
Higdon AN et al. |
Methods for imaging and detecting modification of proteins by reactive lipid species. |
2009 |
Free Radic. Biol. Med. |
pmid:19446632
|
Kar R et al. |
A novel role for MAP1 LC3 in nonautophagic cytoplasmic vacuolation death of cancer cells. |
2009 |
Oncogene |
pmid:19448671
|
Zhang GY et al. |
Activation of peroxisome proliferator-activated receptor-gamma inhibits transforming growth factor-beta1 induction of connective tissue growth factor and extracellular matrix in hypertrophic scar fibroblasts in vitro. |
2009 |
Arch. Dermatol. Res. |
pmid:19466435
|
Wang X et al. |
Potential effects of peroxisome proliferator-activated receptor activator on LPS-induced lung injury in rats. |
2009 |
Pulm Pharmacol Ther |
pmid:19489131
|
Olmos G et al. |
15-Deoxy-Delta(12,14)-prostaglandin-J(2) reveals a new pVHL-independent, lysosomal-dependent mechanism of HIF-1alpha degradation. |
2009 |
Cell. Mol. Life Sci. |
pmid:19458911
|
Brechbuhl HM et al. |
Select cyclopentenone prostaglandins trigger glutathione efflux and the role of ABCG2 transport. |
2009 |
Free Radic. Biol. Med. |
pmid:19520157
|
Ramji DP |
Growth hormone-releasing peptides, CD36, and stimulation of cholesterol efflux: cyclooxygenase-2 is the link. |
2009 |
Cardiovasc. Res. |
pmid:19520704
|
Chiba T et al. |
15-Deoxy-Delta(12,14)-prostaglandin J2 induces IL-8 and GM-CSF in a human airway epithelial cell line (NCI-H292). |
2009 |
Int. Arch. Allergy Immunol. |
pmid:19494510
|
Suk FM et al. |
15-deoxy-Delta(12,14)-prostaglandin J(2) inhibits fibrogenic response in human hepatoma cells. |
2009 |
Toxicol. Lett. |
pmid:19429239
|
Kansanen E et al. |
Regulation of Nrf2-dependent gene expression by 15-deoxy-Delta12,14-prostaglandin J2. |
2009 |
Free Radic. Biol. Med. |
pmid:19573595
|
Cocca C et al. |
15-Deoxi-Delta(12,14)-prostaglandin J2 is a tubulin-binding agent that destabilizes microtubules and induces mitotic arrest. |
2009 |
Biochem. Pharmacol. |
pmid:19576185
|
Bernardo A et al. |
Peroxisome proliferator-activated receptor-gamma agonists promote differentiation and antioxidant defenses of oligodendrocyte progenitor cells. |
2009 |
J. Neuropathol. Exp. Neurol. |
pmid:19535992
|
Comabella M et al. |
Plasma levels of 15d-PGJ are not altered in multiple sclerosis. |
2009 |
Eur. J. Neurol. |
pmid:19538219
|
Qin HD et al. |
Upregulation of peroxisome proliferator-activated receptor-gamma and NADPH oxidases are involved in restenosis after balloon injury. |
2009 |
J. Cell. Physiol. |
pmid:19562688
|
Pena-dos-Santos DR et al. |
Activation of peripheral kappa/delta opioid receptors mediates 15-deoxy-(Delta12,14)-prostaglandin J2 induced-antinociception in rat temporomandibular joint. |
2009 |
Neuroscience |
pmid:19647045
|
Jung WK et al. |
The 15-deoxy-Delta12,14-prostaglandin J2 inhibits LPS-stimulated AKT and NF-kappaB activation and suppresses interleukin-6 in osteoblast-like cells MC3T3E-1. |
2009 |
Life Sci. |
pmid:19409914
|
Bujold K et al. |
CD36-mediated cholesterol efflux is associated with PPARgamma activation via a MAPK-dependent COX-2 pathway in macrophages. |
2009 |
Cardiovasc. Res. |
pmid:19377069
|
Li H and Pauza CD |
Effects of 15-deoxy-delta12,14-prostaglandin J2 (15d-PGJ2) and rosiglitazone on human gammadelta2 T cells. |
2009 |
PLoS ONE |
pmid:19888466
|
Landrier JF et al. |
Adiponectin expression is induced by vitamin E via a peroxisome proliferator-activated receptor gamma-dependent mechanism. |
2009 |
Endocrinology |
pmid:19833717
|
Hironaka A et al. |
15-Deoxy-Delta(12,14)-prostaglandin J(2) impairs the functions of histone acetyltransferases through their insolubilization in cells. |
2009 |
Biochem. Biophys. Res. Commun. |
pmid:19799872
|
Prakash J et al. |
Albumin-binding and tumor vasculature determine the antitumor effect of 15-deoxy-Delta-(12,14)-prostaglandin-J(2) in vivo. |
2009 |
Neoplasia |
pmid:20019843
|
Khanim FL et al. |
Combined bezafibrate and medroxyprogesterone acetate: potential novel therapy for acute myeloid leukaemia. |
2009 |
PLoS ONE |
pmid:19997560
|
Pustovrh MC et al. |
MMP/ TIMP balance is modulated in vitro by 15dPGJ(2) in fetuses and placentas from diabetic rats. |
2009 |
Eur. J. Clin. Invest. |
pmid:19811527
|
Papageorgiou E et al. |
Rosiglitazone attenuates insulin-like growth factor 1 receptor survival signaling in PC-3 cells. |
2008 Jul-Aug |
Mol. Med. |
pmid:18475308
|
Moon Y et al. |
Hypo-responsiveness of interleukin-8 production in human embryonic epithelial intestine 407 cells independent of NF-kappaB pathway: new lessons from endotoxin and ribotoxic deoxynivalenol. |
2008 |
Toxicol. Appl. Pharmacol. |
pmid:18485432
|
Copple IM et al. |
The hepatotoxic metabolite of acetaminophen directly activates the Keap1-Nrf2 cell defense system. |
2008 |
Hepatology |
pmid:18785192
|
Poncin S et al. |
Oxidative stress in the thyroid gland: from harmlessness to hazard depending on the iodine content. |
2008 |
Endocrinology |
pmid:17884933
|
Napimoga MH et al. |
15d-prostaglandin J2 inhibits inflammatory hypernociception: involvement of peripheral opioid receptor. |
2008 |
J. Pharmacol. Exp. Ther. |
pmid:17928570
|
Davidson J et al. |
7beta-hydroxy-epiandrosterone modulation of 15-deoxy-delta12,14-prostaglandin J2, prostaglandin D2 and prostaglandin E2 production from human mononuclear cells. |
2008 |
J. Steroid Biochem. Mol. Biol. |
pmid:18996481
|
Reyes-Martin P et al. |
15-Deoxy-delta12,14-prostaglandin-J(2) up-regulates cyclooxygenase-2 but inhibits prostaglandin-E(2) production through a thiol antioxidant-sensitive mechanism. |
2008 |
Pharmacol. Res. |
pmid:18456507
|
Su RY et al. |
15-deoxy-Delta12,14-prostaglandin J2 up-regulates death receptor 5 gene expression in HCT116 cells: involvement of reactive oxygen species and C/EBP homologous transcription factor gene transcription. |
2008 |
Mol. Cancer Ther. |
pmid:18852146
|
Lee SJ et al. |
15-Deoxy-delta 12,14-prostaglandin J2 induces apoptosis via JNK-mediated mitochondrial pathway in osteoblastic cells. |
2008 |
Toxicology |
pmid:18450357
|
Nagata D et al. |
Peroxisome proliferator-activated receptor-gamma and growth inhibition by its ligands in prostate cancer. |
2008 |
Cancer Detect. Prev. |
pmid:18789607
|
Chearwae W and Bright JJ |
15-deoxy-Delta(12,14)-prostaglandin J(2) and curcumin modulate the expression of toll-like receptors 4 and 9 in autoimmune T lymphocyte. |
2008 |
J. Clin. Immunol. |
pmid:18463970
|
Cruz-Orengo L et al. |
Cutaneous nociception evoked by 15-delta PGJ2 via activation of ion channel TRPA1. |
2008 |
Mol Pain |
pmid:18671867
|
Oku H and Umino T |
Molecular characterization of peroxisome proliferator-activated receptors (PPARs) and their gene expression in the differentiating adipocytes of red sea bream Pagrus major. |
2008 |
Comp. Biochem. Physiol. B, Biochem. Mol. Biol. |
pmid:18691667
|
Ryan AJ et al. |
15-deoxy-Delta12,14-prostaglandin J2 impairs phosphatidylcholine synthesis and induces nuclear accumulation of thiol-modified cytidylyltransferase. |
2008 |
J. Biol. Chem. |
pmid:18614529
|
Ulivi V et al. |
15-deoxy-delta 12,14-prostaglandin J(2) inhibits the synthesis of the acute phase protein SIP24 in cartilage: Involvement of COX-2 in resolution of inflammation. |
2008 |
J. Cell. Physiol. |
pmid:18615580
|
Genovese T et al. |
Effect of cyclopentanone prostaglandin 15-deoxy-delta12,14PGJ2 on early functional recovery from experimental spinal cord injury. |
2008 |
Shock |
pmid:18628687
|
Capobianco E et al. |
Effects of natural ligands of PPARgamma on lipid metabolism in placental tissues from healthy and diabetic rats. |
2008 |
Mol. Hum. Reprod. |
pmid:18621767
|
Tonge D et al. |
Enhancement of axonal regeneration by in vitro conditioning and its inhibition by cyclopentenone prostaglandins. |
2008 |
J. Cell. Sci. |
pmid:18650498
|
Kim EH and Surh YJ |
The role of 15-deoxy-delta(12,14)-prostaglandin J(2), an endogenous ligand of peroxisome proliferator-activated receptor gamma, in tumor angiogenesis. |
2008 |
Biochem. Pharmacol. |
pmid:18771658
|
Kim JW et al. |
15-Deoxy-Delta(12,14)-prostaglandin J(2) rescues PC12 cells from H2O2-induced apoptosis through Nrf2-mediated upregulation of heme oxygenase-1: potential roles of Akt and ERK1/2. |
2008 |
Biochem. Pharmacol. |
pmid:18775681
|
Ho TC et al. |
15-deoxy-Delta(12,14)-prostaglandin J2 induces vascular endothelial cell apoptosis through the sequential activation of MAPKS and p53. |
2008 |
J. Biol. Chem. |
pmid:18718914
|
Chearwae W and Bright JJ |
PPARgamma agonists inhibit growth and expansion of CD133+ brain tumour stem cells. |
2008 |
Br. J. Cancer |
pmid:19018263
|
Lee JH et al. |
The 15-deoxy-delta 12,14-prostaglandin J2 suppresses monocyte chemoattractant protein-1 expression in IFN-gamma-stimulated astrocytes through induction of MAPK phosphatase-1. |
2008 |
J. Immunol. |
pmid:19050284
|
Lian TW et al. |
Fisetin, morin and myricetin attenuate CD36 expression and oxLDL uptake in U937-derived macrophages. |
2008 |
Biochim. Biophys. Acta |
pmid:18662803
|
Jozkowicz A et al. |
15d-PGJ2 upregulates synthesis of IL-8 in endothelial cells through induction of oxidative stress. |
2008 |
Antioxid. Redox Signal. |
pmid:18665800
|
Napimoga MH et al. |
Peroxisome proliferator-activated receptor-gamma ligand, 15-deoxy-Delta12,14-prostaglandin J2, reduces neutrophil migration via a nitric oxide pathway. |
2008 |
J. Immunol. |
pmid:18097063
|
Dubourdeau M et al. |
Opposite roles of STAT and PPARgamma in the induction of p21WAF1 expression by IL-13 in human peripheral blood monocytes. |
2008 |
Eur. Cytokine Netw. |
pmid:19103521
|
GarcÃa-Bueno B et al. |
Stress mediators regulate brain prostaglandin synthesis and peroxisome proliferator-activated receptor-gamma activation after stress in rats. |
2008 |
Endocrinology |
pmid:18079203
|
Muñoz U et al. |
On the mechanism of inhibition of p27 degradation by 15-deoxy-Delta12,14-prostaglandin J2 in lymphoblasts of Alzheimer's disease patients. |
2008 |
Cell. Mol. Life Sci. |
pmid:18818877
|
Ferreira-Silva V et al. |
Effects of 15-deoxy-Delta12, 14 prostaglandin J2 and ciglitazone on human cancer cell cycle progression and death: the role of PPARgamma. |
2008 |
Eur. J. Pharmacol. |
pmid:18054911
|
Zhang J et al. |
Peroxisome proliferator-activated receptor-gamma agonists attenuate angiotensin II-induced collagen type I expression in adventitial fibroblasts. |
2008 |
Clin. Exp. Pharmacol. Physiol. |
pmid:18047631
|
Uchida K and Shibata T |
15-Deoxy-Delta(12,14)-prostaglandin J2: an electrophilic trigger of cellular responses. |
2008 |
Chem. Res. Toxicol. |
pmid:18052108
|
Yu JH et al. |
SOCS 3 and PPAR-gamma ligands inhibit the expression of IL-6 and TGF-beta1 by regulating JAK2/STAT3 signaling in pancreas. |
2008 |
Int. J. Biochem. Cell Biol. |
pmid:18035585
|
Kuboki S et al. |
Peroxisome proliferator-activated receptor-gamma protects against hepatic ischemia/reperfusion injury in mice. |
2008 |
Hepatology |
pmid:18085707
|
Lutzow YS et al. |
15-Deoxy-Delta12,14-prostaglandin J2 induces chemokine expression, oxidative stress and microfilament reorganization in bovine mammary epithelial cells. |
2008 |
J. Dairy Res. |
pmid:18226310
|
Kerr BJ et al. |
The protective effects of 15-deoxy-delta-(12,14)-prostaglandin J2 in spinal cord injury. |
2008 |
Glia |
pmid:18205174
|
Choi IK et al. |
PPAR-gamma ligand promotes the growth of APC-mutated HT-29 human colon cancer cells in vitro and in vivo. |
2008 |
Invest New Drugs |
pmid:18161004
|
Hounoki H et al. |
Activation of peroxisome proliferator-activated receptor gamma inhibits TNF-alpha-mediated osteoclast differentiation in human peripheral monocytes in part via suppression of monocyte chemoattractant protein-1 expression. |
2008 |
Bone |
pmid:18242157
|
Kim EH et al. |
15-Deoxy-Delta12,14-prostaglandin J2 induces COX-2 expression through Akt-driven AP-1 activation in human breast cancer cells: a potential role of ROS. |
2008 |
Carcinogenesis |
pmid:18192694
|
Crabb SJ et al. |
BAG-1 inhibits PPARgamma-induced cell death, but not PPARgamma-induced transcription, cell cycle arrest or differentiation in breast cancer cells. |
2008 |
Oncol. Rep. |
pmid:18288403
|
Hong HY et al. |
Up-regulation of heme oxygenase-1 expression through the Rac1/NADPH oxidase/ROS/p38 signaling cascade mediates the anti-inflammatory effect of 15-deoxy-delta 12,14-prostaglandin J2 in murine macrophages. |
2008 |
FEBS Lett. |
pmid:18291107
|
Liu Y et al. |
Increased expression of the peroxisome proliferator-activated receptor gamma in the immune system of weaned pigs after Escherichia coli lipopolysaccharide injection. |
2008 |
Vet. Immunol. Immunopathol. |
pmid:18394717
|
Kimura H et al. |
A natural PPAR-gamma agonist, 15-deoxy-delta 12,14-prostaglandin J2, may act as an enhancer of PAI-1 in human proximal renal tubular cells under hypoxic and inflammatory conditions. |
2008 |
Nephrol. Dial. Transplant. |
pmid:18367541
|