| MeSH term | MeSH ID | Detail |
|---|---|---|
| Graves Ophthalmopathy | D049970 | 3 associated lipids |
| Leukemia, B-Cell | D015448 | 3 associated lipids |
| Goiter | D006042 | 4 associated lipids |
| Actinobacillus Infections | D000189 | 4 associated lipids |
| Lymphoma, T-Cell | D016399 | 11 associated lipids |
| Myocardial Infarction | D009203 | 21 associated lipids |
| Fibrosis | D005355 | 23 associated lipids |
| Lymphoma, B-Cell | D016393 | 24 associated lipids |
| Autoimmune Diseases | D001327 | 27 associated lipids |
| Liver Cirrhosis, Experimental | D008106 | 36 associated lipids |
| Hyperalgesia | D006930 | 42 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Parkinson Disease | D010300 | 53 associated lipids |
| Weight Loss | D015431 | 56 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Liver Cirrhosis | D008103 | 67 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Carcinoma, Non-Small-Cell Lung | D002289 | 72 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
15-deoxy-delta-12,14-PGJ2
15-deoxy-delta-12,14-pgj2 is a lipid of Fatty Acyls (FA) class. 15-deoxy-delta-12,14-pgj2 is associated with abnormalities such as Dehydration and Myocardial Ischemia. The involved functions are known as Binding (Molecular Function), Inflammation, Alveolar ventilation function, Stimulus and Process. 15-deoxy-delta-12,14-pgj2 often locates in Cytosol, Myocardial tissue and Heart tissue. The associated genes with 15-deoxy-delta-12,14-PGJ2 are Homologous Gene and G-substrate. The related lipids are 15-deoxyprostaglandin J2 and Lipopolysaccharides.
Cross Reference
Introduction
To understand associated biological information of 15-deoxy-delta-12,14-PGJ2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 15-deoxy-delta-12,14-PGJ2?
15-deoxy-delta-12,14-PGJ2 is suspected in Dehydration, Myocardial Ischemia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 15-deoxy-delta-12,14-PGJ2
PubChem Associated disorders and diseases
What pathways are associated with 15-deoxy-delta-12,14-PGJ2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 15-deoxy-delta-12,14-PGJ2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 15-deoxy-delta-12,14-PGJ2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 15-deoxy-delta-12,14-PGJ2?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with 15-deoxy-delta-12,14-PGJ2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 15-deoxy-delta-12,14-PGJ2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 15-deoxy-delta-12,14-PGJ2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Marx N et al. | PPARgamma activation in human endothelial cells increases plasminogen activator inhibitor type-1 expression: PPARgamma as a potential mediator in vascular disease. | 1999 | Arterioscler. Thromb. Vasc. Biol. | pmid:10073956 |
| Xin X et al. | Peroxisome proliferator-activated receptor gamma ligands are potent inhibitors of angiogenesis in vitro and in vivo. | 1999 | J. Biol. Chem. | pmid:10085162 |
| Petrova TV et al. | Cyclopentenone prostaglandins suppress activation of microglia: down-regulation of inducible nitric-oxide synthase by 15-deoxy-Delta12,14-prostaglandin J2. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10200320 |
| Goetze S et al. | PPAR gamma-ligands inhibit migration mediated by multiple chemoattractants in vascular smooth muscle cells. | 1999 | J. Cardiovasc. Pharmacol. | pmid:10226869 |
| Torii SI et al. | Thiazolidinedione induces the adipose differentiation of fibroblast-like cells resident within bovine skeletal muscle. | 1998 | Cell Biol. Int. | pmid:10328850 |
| Bishop-Bailey D and Hla T | Endothelial cell apoptosis induced by the peroxisome proliferator-activated receptor (PPAR) ligand 15-deoxy-Delta12, 14-prostaglandin J2. | 1999 | J. Biol. Chem. | pmid:10358055 |
| Chinery R et al. | Prostaglandin J2 and 15-deoxy-delta12,14-prostaglandin J2 induce proliferation of cyclooxygenase-depleted colorectal cancer cells. | 1999 | Cancer Res. | pmid:10364000 |
| Gilroy DW et al. | Inducible cyclooxygenase may have anti-inflammatory properties. | 1999 | Nat. Med. | pmid:10371510 |
| Kwon G et al. | Tumor necrosis factor alpha-induced pancreatic beta-cell insulin resistance is mediated by nitric oxide and prevented by 15-deoxy-Delta12,14-prostaglandin J2 and aminoguanidine. A role for peroxisome proliferator-activated receptor gamma activation and inos expression. | 1999 | J. Biol. Chem. | pmid:10373483 |
| Herbertsson H et al. | The 650-kDa 12(S)-hydroxyeicosatetraenoic acid binding complex: occurrence in human platelets, identification of hsp90 as a constituent, and binding properties of its 50-kDa subunit. | 1999 | Arch. Biochem. Biophys. | pmid:10375396 |
| Sinha D et al. | 15-Deoxy-delta(12,14) prostaglandin J2: a putative endogenous promoter of adipogenesis suppresses the ob gene. | 1999 | Metab. Clin. Exp. | pmid:10381155 |
| Pelton PD et al. | PPARgamma activation induces the expression of the adipocyte fatty acid binding protein gene in human monocytes. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10425206 |
| Su CG et al. | A novel therapy for colitis utilizing PPAR-gamma ligands to inhibit the epithelial inflammatory response. | 1999 | J. Clin. Invest. | pmid:10449430 |
| Keelan JA et al. | 15-Deoxy-Delta(12,14)-prostaglandin J(2), a ligand for peroxisome proliferator-activated receptor-gamma, induces apoptosis in JEG3 choriocarcinoma cells. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10471366 |
| Valmaseda A et al. | Opposite regulation of PPAR-alpha and -gamma gene expression by both their ligands and retinoic acid in brown adipocytes. | 1999 | Mol. Cell. Endocrinol. | pmid:10509805 |
| Jang MK et al. | Regulation of ferritin light chain gene expression by oxidized low-density lipoproteins in human monocytic THP-1 cells. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10558912 |
| Vaidya S et al. | 15-Deoxy-Delta12,1412,14-prostaglandin J2 inhibits the beta2 integrin-dependent oxidative burst: involvement of a mechanism distinct from peroxisome proliferator-activated receptor gamma ligation. | 1999 | J. Immunol. | pmid:10570310 |
| Yang T et al. | Expression of peroxisomal proliferator-activated receptors and retinoid X receptors in the kidney. | 1999 | Am. J. Physiol. | pmid:10600944 |
| Galli A et al. | Peroxisome proliferator-activated receptor gamma transcriptional regulation is involved in platelet-derived growth factor-induced proliferation of human hepatic stellate cells. | 2000 | Hepatology | pmid:10613734 |