| MeSH term | MeSH ID | Detail |
|---|---|---|
| Leukemia, B-Cell | D015448 | 3 associated lipids |
| Graves Ophthalmopathy | D049970 | 3 associated lipids |
| Actinobacillus Infections | D000189 | 4 associated lipids |
| Goiter | D006042 | 4 associated lipids |
| Lymphoma, T-Cell | D016399 | 11 associated lipids |
| Myocardial Infarction | D009203 | 21 associated lipids |
| Fibrosis | D005355 | 23 associated lipids |
| Lymphoma, B-Cell | D016393 | 24 associated lipids |
| Autoimmune Diseases | D001327 | 27 associated lipids |
| Liver Cirrhosis, Experimental | D008106 | 36 associated lipids |
| Hyperalgesia | D006930 | 42 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Parkinson Disease | D010300 | 53 associated lipids |
| Weight Loss | D015431 | 56 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Liver Cirrhosis | D008103 | 67 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Carcinoma, Non-Small-Cell Lung | D002289 | 72 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
15-deoxy-delta-12,14-PGJ2
15-deoxy-delta-12,14-pgj2 is a lipid of Fatty Acyls (FA) class. 15-deoxy-delta-12,14-pgj2 is associated with abnormalities such as Dehydration and Myocardial Ischemia. The involved functions are known as Binding (Molecular Function), Inflammation, Alveolar ventilation function, Stimulus and Process. 15-deoxy-delta-12,14-pgj2 often locates in Cytosol, Myocardial tissue and Heart tissue. The associated genes with 15-deoxy-delta-12,14-PGJ2 are Homologous Gene and G-substrate. The related lipids are 15-deoxyprostaglandin J2 and Lipopolysaccharides.
Cross Reference
Introduction
To understand associated biological information of 15-deoxy-delta-12,14-PGJ2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 15-deoxy-delta-12,14-PGJ2?
15-deoxy-delta-12,14-PGJ2 is suspected in Dehydration, Myocardial Ischemia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 15-deoxy-delta-12,14-PGJ2
PubChem Associated disorders and diseases
What pathways are associated with 15-deoxy-delta-12,14-PGJ2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 15-deoxy-delta-12,14-PGJ2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 15-deoxy-delta-12,14-PGJ2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 15-deoxy-delta-12,14-PGJ2?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with 15-deoxy-delta-12,14-PGJ2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 15-deoxy-delta-12,14-PGJ2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 15-deoxy-delta-12,14-PGJ2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kumar AP et al. | Manganese superoxide dismutase is a promising target for enhancing chemosensitivity of basal-like breast carcinoma. | 2014 | Antioxid. Redox Signal. | pmid:23964924 |
| Han H et al. | 15-Deoxy-delta 12,14-prostaglandin J2 (15d-PGJ 2) sensitizes human leukemic HL-60 cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through Akt downregulation. | 2007 | Apoptosis | pmid:17786557 |
| Syeda PK et al. | Generation of monoclonal antibody for 15-deoxy-Δ¹²,¹â´-prostaglandin Jâ‚‚ and development of enzyme-linked immunosorbent assay for its quantification in culture medium of adipocytes. | 2012 | Appl. Biochem. Biotechnol. | pmid:22391692 |
| Sánchez-Gómez FJ et al. | Direct evidence for the covalent modification of glutathione-S-transferase P1-1 by electrophilic prostaglandins: implications for enzyme inactivation and cell survival. | 2007 | Arch. Biochem. Biophys. | pmid:17169324 |
| Mueller C et al. | Peroxisome proliferator-activated receptor gamma ligands attenuate immunological symptoms of experimental allergic asthma. | 2003 | Arch. Biochem. Biophys. | pmid:14522590 |
| Herbertsson H et al. | The 650-kDa 12(S)-hydroxyeicosatetraenoic acid binding complex: occurrence in human platelets, identification of hsp90 as a constituent, and binding properties of its 50-kDa subunit. | 1999 | Arch. Biochem. Biophys. | pmid:10375396 |
| Zhang GY et al. | Activation of peroxisome proliferator-activated receptor-gamma inhibits transforming growth factor-beta1 induction of connective tissue growth factor and extracellular matrix in hypertrophic scar fibroblasts in vitro. | 2009 | Arch. Dermatol. Res. | pmid:19466435 |
| Kang HY et al. | Peroxisome proliferator-activated receptors-gamma activator, ciglitazone, inhibits human melanocyte growth through induction of apoptosis. | 2006 | Arch. Dermatol. Res. | pmid:16474974 |
| Lin TN et al. | 15d-prostaglandin J2 protects brain from ischemia-reperfusion injury. | 2006 | Arterioscler. Thromb. Vasc. Biol. | pmid:16385084 |
| Migita H and Morser J | 15-deoxy-Delta12,14-prostaglandin J2 (15d-PGJ2) signals through retinoic acid receptor-related orphan receptor-alpha but not peroxisome proliferator-activated receptor-gamma in human vascular endothelial cells: the effect of 15d-PGJ2 on tumor necrosis factor-alpha-induced gene expression. | 2005 | Arterioscler. Thromb. Vasc. Biol. | pmid:15662020 |