| MeSH term | MeSH ID | Detail |
|---|---|---|
| Graves Ophthalmopathy | D049970 | 3 associated lipids |
| Leukemia, B-Cell | D015448 | 3 associated lipids |
| Goiter | D006042 | 4 associated lipids |
| Actinobacillus Infections | D000189 | 4 associated lipids |
| Lymphoma, T-Cell | D016399 | 11 associated lipids |
| Myocardial Infarction | D009203 | 21 associated lipids |
| Fibrosis | D005355 | 23 associated lipids |
| Lymphoma, B-Cell | D016393 | 24 associated lipids |
| Autoimmune Diseases | D001327 | 27 associated lipids |
| Liver Cirrhosis, Experimental | D008106 | 36 associated lipids |
| Hyperalgesia | D006930 | 42 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Parkinson Disease | D010300 | 53 associated lipids |
| Weight Loss | D015431 | 56 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Liver Cirrhosis | D008103 | 67 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Carcinoma, Non-Small-Cell Lung | D002289 | 72 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
15-deoxy-delta-12,14-PGJ2
15-deoxy-delta-12,14-pgj2 is a lipid of Fatty Acyls (FA) class. 15-deoxy-delta-12,14-pgj2 is associated with abnormalities such as Dehydration and Myocardial Ischemia. The involved functions are known as Binding (Molecular Function), Inflammation, Alveolar ventilation function, Stimulus and Process. 15-deoxy-delta-12,14-pgj2 often locates in Cytosol, Myocardial tissue and Heart tissue. The associated genes with 15-deoxy-delta-12,14-PGJ2 are Homologous Gene and G-substrate. The related lipids are 15-deoxyprostaglandin J2 and Lipopolysaccharides.
Cross Reference
Introduction
To understand associated biological information of 15-deoxy-delta-12,14-PGJ2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 15-deoxy-delta-12,14-PGJ2?
15-deoxy-delta-12,14-PGJ2 is suspected in Dehydration, Myocardial Ischemia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 15-deoxy-delta-12,14-PGJ2
PubChem Associated disorders and diseases
What pathways are associated with 15-deoxy-delta-12,14-PGJ2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 15-deoxy-delta-12,14-PGJ2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 15-deoxy-delta-12,14-PGJ2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 15-deoxy-delta-12,14-PGJ2?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with 15-deoxy-delta-12,14-PGJ2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 15-deoxy-delta-12,14-PGJ2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 15-deoxy-delta-12,14-PGJ2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hayden RE et al. | Treatment of primary CLL cells with bezafibrate and medroxyprogesterone acetate induces apoptosis and represses the pro-proliferative signal of CD40-ligand, in part through increased 15dDelta12,14,PGJ2. | 2009 | Leukemia | pmid:18923439 |
| Ricart KC et al. | The permissive role of mitochondria in the induction of haem oxygenase-1 in endothelial cells. | 2009 | Biochem. J. | pmid:19161347 |
| Lee DR et al. | 15-Deoxy-Delta(12,14)-prostaglandin J(2) induces mitochondrial-dependent apoptosis through inhibition of PKA/NF-kappaB in renal proximal epithelial cells. | 2009 | Toxicology | pmid:19167456 |
| Tsuji T et al. | Reduction of nuclear peroxisome proliferator-activated receptor gamma expression in methamphetamine-induced neurotoxicity and neuroprotective effects of ibuprofen. | 2009 | Neurochem. Res. | pmid:18946735 |
| Kalantari P et al. | 15-Deoxy-Delta12,14-prostaglandin J2 inhibits HIV-1 transactivating protein, Tat, through covalent modification. | 2009 | FASEB J. | pmid:19299483 |
| Shin SW et al. | 15d-PGJ2 induces apoptosis by reactive oxygen species-mediated inactivation of Akt in leukemia and colorectal cancer cells and shows in vivo antitumor activity. | 2009 | Clin. Cancer Res. | pmid:19690198 |
| Kim DH et al. | 15-Deoxy-Delta12,14-prostaglandin J2 upregulates the expression of heme oxygenase-1 and subsequently matrix metalloproteinase-1 in human breast cancer cells: possible roles of iron and ROS. | 2009 | Carcinogenesis | pmid:19136476 |
| Waku T et al. | Atomic structure of mutant PPARgamma LBD complexed with 15d-PGJ2: novel modulation mechanism of PPARgamma/RXRalpha function by covalently bound ligands. | 2009 | FEBS Lett. | pmid:19101554 |
| Dong YW et al. | Suppression of pancreatic carcinoma growth by activating peroxisome proliferator-activated receptor gamma involves angiogenesis inhibition. | 2009 | World J. Gastroenterol. | pmid:19152448 |
| Baregamian N et al. | PPAR-gamma agonist protects against intestinal injury during necrotizing enterocolitis. | 2009 | Biochem. Biophys. Res. Commun. | pmid:19114032 |
| Kar R et al. | A novel role for MAP1 LC3 in nonautophagic cytoplasmic vacuolation death of cancer cells. | 2009 | Oncogene | pmid:19448671 |
| Brechbuhl HM et al. | Select cyclopentenone prostaglandins trigger glutathione efflux and the role of ABCG2 transport. | 2009 | Free Radic. Biol. Med. | pmid:19520157 |
| Ramji DP | Growth hormone-releasing peptides, CD36, and stimulation of cholesterol efflux: cyclooxygenase-2 is the link. | 2009 | Cardiovasc. Res. | pmid:19520704 |
| Suk FM et al. | 15-deoxy-Delta(12,14)-prostaglandin J(2) inhibits fibrogenic response in human hepatoma cells. | 2009 | Toxicol. Lett. | pmid:19429239 |
| Kansanen E et al. | Regulation of Nrf2-dependent gene expression by 15-deoxy-Delta12,14-prostaglandin J2. | 2009 | Free Radic. Biol. Med. | pmid:19573595 |
| Cocca C et al. | 15-Deoxi-Delta(12,14)-prostaglandin J2 is a tubulin-binding agent that destabilizes microtubules and induces mitotic arrest. | 2009 | Biochem. Pharmacol. | pmid:19576185 |
| Bernardo A et al. | Peroxisome proliferator-activated receptor-gamma agonists promote differentiation and antioxidant defenses of oligodendrocyte progenitor cells. | 2009 | J. Neuropathol. Exp. Neurol. | pmid:19535992 |
| Comabella M et al. | Plasma levels of 15d-PGJ are not altered in multiple sclerosis. | 2009 | Eur. J. Neurol. | pmid:19538219 |
| Qin HD et al. | Upregulation of peroxisome proliferator-activated receptor-gamma and NADPH oxidases are involved in restenosis after balloon injury. | 2009 | J. Cell. Physiol. | pmid:19562688 |
| Pena-dos-Santos DR et al. | Activation of peripheral kappa/delta opioid receptors mediates 15-deoxy-(Delta12,14)-prostaglandin J2 induced-antinociception in rat temporomandibular joint. | 2009 | Neuroscience | pmid:19647045 |