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The antagonistic actions of endogenous interleukin-1β and 15-deoxy-Δ12,14-prostaglandin J2 regulate the temporal synthesis of matrix metalloproteinase-9 in sheared chondrocytes. |
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Chemoattractant receptor homologous to the T helper 2 cell (CRTH2) is not expressed in human amniocytes and myocytes. |
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PLoS ONE |
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J. Biol. Chem. |
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Transcription of liver X receptor is down-regulated by 15-deoxy-Δ(12,14)-prostaglandin J(2) through oxidative stress in human neutrophils. |
2012 |
PLoS ONE |
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Stable expression of lipocalin-type prostaglandin D synthase in cultured preadipocytes impairs adipogenesis program independently of endogenous prostanoids. |
2012 |
Exp. Cell Res. |
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Biochim. Biophys. Acta |
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Br. J. Pharmacol. |
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Combination of midazolam and a cyclooxygenase-2 inhibitor inhibits lipopolysaccharide-induced interleukin-6 production in human peripheral blood mononuclear cells. |
2012 |
Immunopharmacol Immunotoxicol |
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High sodium butyrate levels induce MDR1 activation in colorectal cells: Impact of 15-deoxy-Δ(12,14)-prostaglandin J(2) on the resistance to saquinavir. |
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Biochem. Biophys. Res. Commun. |
pmid:22293191
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Identification, organ expression and ligand-dependent expression levels of peroxisome proliferator activated receptors in grass carp (Ctenopharyngodon idella). |
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Comp. Biochem. Physiol. C Toxicol. Pharmacol. |
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15-Deoxy-Δ12,14-prostaglandin J₂ modulates manganese-induced activation of the NF-κB, Nrf2, and PI3K pathways in astrocytes. |
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Cytotoxicity of 15-deoxy-Δ(12,14)-prostaglandin J(2) through PPARγ-independent pathway and the involvement of the JNK and Akt pathway in renal cell carcinoma. |
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Int J Med Sci |
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Exploring the cyclooxygenase 2 (COX2)/15d-Δ(12,14)PGJ(2) system in hamster Sertoli cells: regulation by FSH/testosterone and relevance to glucose uptake. |
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PPAR-γ agonists, mainly 15d-PGJ(2), reduce eosinophil recruitment following allergen challenge. |
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Cell. Immunol. |
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Electrophilic PPARγ ligands inhibit corneal fibroblast to myofibroblast differentiation in vitro: a potentially novel therapy for corneal scarring. |
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Exp. Eye Res. |
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Prostaglandin D2 inhibits hair growth and is elevated in bald scalp of men with androgenetic alopecia. |
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Sci Transl Med |
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The prostanoid 15-deoxy-Δ12,14-prostaglandin-j2 reduces lung inflammation and protects mice against lethal influenza infection. |
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J. Infect. Dis. |
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15-Deoxy-Δ¹²,¹â´-prostaglandin Jâ‚‚-glycerol, a putative metabolite of 2-arachidonyl glycerol and a peroxisome proliferator-activated receptor γ ligand, modulates nuclear factor of activated T cells. |
2012 |
J. Pharmacol. Exp. Ther. |
pmid:22700433
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Observation of two modes of inhibition of human microsomal prostaglandin E synthase 1 by the cyclopentenone 15-deoxy-Δ(12,14)-prostaglandin J(2). |
2012 |
Biochemistry |
pmid:22356188
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Possible involvement of transient receptor potential channels in electrophile-induced insulin secretion from RINm5F cells. |
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