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Regulation of retinoic acid receptor beta expression by peroxisome proliferator-activated receptor gamma ligands in cancer cells. |
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Cancer Res. |
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Activation of peroxisome proliferator-activated receptors alpha and gamma1 inhibits human smooth muscle cell proliferation. |
2003 |
Mol. Cell. Biochem. |
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Inhibition of IFN-gamma-mediated inducible nitric oxide synthase induction by the peroxisome proliferator-activated receptor gamma agonist, 15-deoxy-delta 12,14-prostaglandin J2, involves inhibition of the upstream Janus kinase/STAT1 signaling pathway. |
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J. Immunol. |
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Biochem. Biophys. Res. Commun. |
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Neuroprotective effects of PPARgamma agonists against oxidative insults in HT-22 cells. |
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Eur. J. Pharmacol. |
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Oxidized low-density lipoprotein and 15-deoxy-delta 12,14-PGJ2 increase mitochondrial complex I activity in endothelial cells. |
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Am. J. Physiol. Heart Circ. Physiol. |
pmid:12881207
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PPARgamma inhibition of cyclooxygenase-2, PGE2 synthase, and inducible nitric oxide synthase in cardiac myocytes. |
2003 |
Hypertension |
pmid:12885795
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Heme oxygenase-1 is an antifibrogenic protein in human hepatic myofibroblasts. |
2003 |
Gastroenterology |
pmid:12891549
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Pritts EA et al. |
Peroxisome proliferator-activated receptor-gamma ligand inhibition of RANTES production by human endometriotic stromal cells is mediated through an upstream promoter element. |
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Fertil. Steril. |
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Selective activation of PPARgamma inhibits pancreatic cancer invasion and decreases expression of tissue plasminogen activator. |
2003 |
Surgery |
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Peroxisome proliferator-activated receptor-gamma activator 15-deoxy-Delta12,14-prostaglandin J2 inhibits neuroblastoma cell growth through induction of apoptosis: association with extracellular signal-regulated kinase signal pathway. |
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J. Pharmacol. Exp. Ther. |
pmid:12966153
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The PPAR-gamma ligand 15-deoxy(delta12,14) prostaglandin J2 reduces the liver injury in endotoxic shock. |
2003 |
Eur. J. Pharmacol. |
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Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2, ligands of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma), reduce ischaemia/reperfusion injury of the gut. |
2003 |
Br. J. Pharmacol. |
pmid:12970094
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J. Clin. Invest. |
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J. Clin. Invest. |
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Exp. Mol. Med. |
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Apoptosis in human oral squamous cell carcinomas is induced by 15-deoxy-delta 12,14-prostaglandin J2 but not by troglitazone. |
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J. Dent. Res. |
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15-Deoxy-delta 12,14-prostaglandin J2 inhibits the expression of granulocyte-macrophage colony-stimulating factor in endothelial cells stimulated with lipopolysaccharide. |
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Prostaglandins Other Lipid Mediat. |
pmid:14518569
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Peroxisome proliferator-activated receptor gamma ligands attenuate immunological symptoms of experimental allergic asthma. |
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Arch. Biochem. Biophys. |
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Molecular basis for the direct inhibition of AP-1 DNA binding by 15-deoxy-Delta 12,14-prostaglandin J2. |
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Korean J Gastroenterol |
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Metalloproteinase expression in PMA-stimulated THP-1 cells. Effects of peroxisome proliferator-activated receptor-gamma (PPAR gamma) agonists and 9-cis-retinoic acid. |
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J. Biol. Chem. |
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15-deoxy-delta12,14-prostaglandin J2 regulates the functional state and the survival of microglial cells through multiple molecular mechanisms. |
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J. Neurochem. |
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15-Deoxy-Delta12,14-prostaglandin J2 regulates endogenous Cot MAPK kinase kinase 1 activity induced by lipopolysaccharide. |
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15d-PGJ2 inhibits cell growth and induces apoptosis of MCG-803 human gastric cancer cell line. |
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World J. Gastroenterol. |
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Antiinflammatory roles of peroxisome proliferator-activated receptor gamma in human alveolar macrophages. |
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Am. J. Respir. Crit. Care Med. |
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FASEB J. |
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15-deoxy-delta-12-14-PGJ2 regulates apoptosis induction and nuclear factor-kappaB activation via a peroxisome proliferator-activated receptor-gamma-independent mechanism in hepatocellular carcinoma. |
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Lab. Invest. |
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Inhibition of interleukin-4 production in CD4+ T cells by peroxisome proliferator-activated receptor-gamma (PPAR-gamma) ligands: involvement of physical association between PPAR-gamma and the nuclear factor of activated T cells transcription factor. |
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Mol. Pharmacol. |
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15-Deoxy-Delta(12,14)-prostaglandin J2 induces apoptosis through activation of the CHOP gene in HeLa cells. |
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Biochem. Biophys. Res. Commun. |
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Effect of 15-deoxy-delta12,14-prostaglandin J2 on IL-1beta-induced expression of epithelial neutrophil-activating protein-78 in human endothelial cells. |
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Prostaglandins Leukot. Essent. Fatty Acids |
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Activation of nuclear receptors by prostaglandins. |
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Thromb. Res. |
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Novel binding sites of 15-deoxy-Delta12,14-prostaglandin J2 in plasma membranes from primary rat cortical neurons. |
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Exp. Cell Res. |
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Cyclopentenone prostaglandins induce lymphocyte apoptosis by activating the mitochondrial apoptosis pathway independent of external death receptor signaling. |
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J. Immunol. |
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The effect of peroxisome proliferator-activated receptor-gamma ligand on urological cancer cells. |
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Int. J. Mol. Med. |
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The PPARgamma ligand, 15-Deoxy-Delta12,14-PGJ2, regulates apoptosis-related protein expression in cholangio cell carcinoma cells. |
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Cellular mechanisms of redox cell signalling: role of cysteine modification in controlling antioxidant defences in response to electrophilic lipid oxidation products. |
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Biochem. J. |
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Deactivation of murine alveolar macrophages by peroxisome proliferator-activated receptor-gamma ligands. |
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Am. J. Physiol. Lung Cell Mol. Physiol. |
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Prolonged exposure of microglia to lipopolysaccharide modifies the intracellular signaling pathways and selectively promotes prostaglandin E2 synthesis. |
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J. Neurochem. |
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Rosiglitazone prevents the impairment of human islet function induced by fatty acids: evidence for a role of PPARgamma2 in the modulation of insulin secretion. |
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Am. J. Physiol. Endocrinol. Metab. |
pmid:14625208
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An endogenous electrophile that modulates the regulatory mechanism of protein turnover: inhibitory effects of 15-deoxy-Delta 12,14-prostaglandin J2 on proteasome. |
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Biochemistry |
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Effect of 15-deoxy-delta 12,14-prostaglandin J2 on acute lung injury induced by lipopolysaccharide in mice. |
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Eur. J. Pharmacol. |
pmid:14642794
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Expression of the murine glutathione S-transferase alpha3 (GSTA3) subunit is markedly induced during adipocyte differentiation: activation of the GSTA3 gene promoter by the pro-adipogenic eicosanoid 15-deoxy-Delta12,14-prostaglandin J2. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:14652005
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15-deoxy prostaglandin J2 enhances allyl alcohol-induced toxicity in rat hepatocytes. |
2004 |
Toxicol. Sci. |
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Expression of NAG-1, a transforming growth factor-beta superfamily member, by troglitazone requires the early growth response gene EGR-1. |
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J. Biol. Chem. |
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Peroxisome proliferator activator receptor-gamma ligands, 15-deoxy-Delta(12,14)-prostaglandin J2 and ciglitazone, reduce systemic inflammation in polymicrobial sepsis by modulation of signal transduction pathways. |
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J. Immunol. |
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Kumar AP et al. |
Peroxisome proliferator-activated receptor gamma ligands regulate myeloperoxidase expression in macrophages by an estrogen-dependent mechanism involving the -463GA promoter polymorphism. |
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J. Biol. Chem. |
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Transcription factor Nrf2 regulates inflammation by mediating the effect of 15-deoxy-Delta(12,14)-prostaglandin j(2). |
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Mol. Cell. Biol. |
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