15-deoxy-delta-12,14-pgj2 is a lipid of Fatty Acyls (FA) class. 15-deoxy-delta-12,14-pgj2 is associated with abnormalities such as Dehydration and Myocardial Ischemia. The involved functions are known as Binding (Molecular Function), Inflammation, Alveolar ventilation function, Stimulus and Process. 15-deoxy-delta-12,14-pgj2 often locates in Cytosol, Myocardial tissue and Heart tissue. The associated genes with 15-deoxy-delta-12,14-PGJ2 are Homologous Gene and G-substrate. The related lipids are 15-deoxyprostaglandin J2 and Lipopolysaccharides.
To understand associated biological information of 15-deoxy-delta-12,14-PGJ2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
15-deoxy-delta-12,14-PGJ2 is suspected in Dehydration, Myocardial Ischemia and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 15-deoxy-delta-12,14-PGJ2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Korbecki J et al. | Cyclooxygenase pathways. | 2014 | Acta Biochim. Pol. | pmid:25343148 |
Paakinaho V et al. | Electrophilic lipid mediator 15-deoxy-Δ12,14-prostaglandin j2 modifies glucocorticoid signaling via receptor SUMOylation. | 2014 | Mol. Cell. Biol. | pmid:24980431 |
Mantel A et al. | Aldo-keto reductase 1C3 is overexpressed in skin squamous cell carcinoma (SCC) and affects SCC growth via prostaglandin metabolism. | 2014 | Exp. Dermatol. | pmid:24917395 |
Tang J et al. | Aspirin treatment improved mesenchymal stem cell immunomodulatory properties via the 15d-PGJ2/PPARγ/TGF-β1 pathway. | 2014 | Stem Cells Dev. | pmid:24730450 |
Liu C et al. | 15d-PGJâ‚‚ decreases PGEâ‚‚ synthesis in HBx-positive liver cells by interfering EGR1 binding to mPGES-1 promoter. | 2014 | Biochem. Pharmacol. | pmid:25108236 |
Koyani CN et al. | 15-deoxy-Δ¹²,¹â´-PGJâ‚‚ promotes inflammation and apoptosis in cardiomyocytes via the DP2/MAPK/TNFα axis. | 2014 | Int. J. Cardiol. | pmid:24698234 |
Wang C et al. | A chemoproteomic platform to quantitatively map targets of lipid-derived electrophiles. | 2014 | Nat. Methods | pmid:24292485 |
GarcÃa-Bueno B et al. | Pro-/anti-inflammatory dysregulation in patients with first episode of psychosis: toward an integrative inflammatory hypothesis of schizophrenia. | 2014 | Schizophr Bull | pmid:23486748 |
Katsumata Y et al. | Endogenous prostaglandin D2 and its metabolites protect the heart against ischemia-reperfusion injury by activating Nrf2. | 2014 | Hypertension | pmid:24101662 |
Casali CI et al. | Coordinate regulation between the nuclear receptor peroxisome proliferator-activated receptor-γ and cyclooxygenase-2 in renal epithelial cells. | 2014 | Biochem. Pharmacol. | pmid:24915420 |