15-deoxy-delta-12,14-PGJ2

15-deoxy-delta-12,14-pgj2 is a lipid of Fatty Acyls (FA) class. 15-deoxy-delta-12,14-pgj2 is associated with abnormalities such as Dehydration and Myocardial Ischemia. The involved functions are known as Binding (Molecular Function), Inflammation, Alveolar ventilation function, Stimulus and Process. 15-deoxy-delta-12,14-pgj2 often locates in Cytosol, Myocardial tissue and Heart tissue. The associated genes with 15-deoxy-delta-12,14-PGJ2 are Homologous Gene and G-substrate. The related lipids are 15-deoxyprostaglandin J2 and Lipopolysaccharides.

Cross Reference

Introduction

To understand associated biological information of 15-deoxy-delta-12,14-PGJ2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 15-deoxy-delta-12,14-PGJ2?

15-deoxy-delta-12,14-PGJ2 is suspected in Dehydration, Myocardial Ischemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 15-deoxy-delta-12,14-PGJ2

MeSH term MeSH ID Detail
Actinobacillus Infections D000189 4 associated lipids
Arteriosclerosis D001161 86 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Body Weight D001835 333 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Brain Ischemia D002545 89 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Fibrosis D005355 23 associated lipids
Goiter D006042 4 associated lipids
Hemolysis D006461 131 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hyperalgesia D006930 42 associated lipids
Inflammation D007249 119 associated lipids
Insulin Resistance D007333 99 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Lung Neoplasms D008175 171 associated lipids
Myocardial Infarction D009203 21 associated lipids
Pain D010146 64 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Parkinson Disease D010300 53 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Thrombosis D013927 49 associated lipids
Weight Loss D015431 56 associated lipids
Leukemia, B-Cell D015448 3 associated lipids
Lymphoma, B-Cell D016393 24 associated lipids
Lymphoma, T-Cell D016399 11 associated lipids
Graves Ophthalmopathy D049970 3 associated lipids
Atherosclerosis D050197 85 associated lipids
Per page 10 20 50 | Total 30

PubChem Associated disorders and diseases

What pathways are associated with 15-deoxy-delta-12,14-PGJ2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 15-deoxy-delta-12,14-PGJ2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with 15-deoxy-delta-12,14-PGJ2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 15-deoxy-delta-12,14-PGJ2?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with 15-deoxy-delta-12,14-PGJ2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 15-deoxy-delta-12,14-PGJ2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 15-deoxy-delta-12,14-PGJ2

Download all related citations
Per page 10 20 50 100 | Total 940
Authors Title Published Journal PubMed Link
Park KS et al. Neuronal differentiation of embryonic midbrain cells by upregulation of peroxisome proliferator-activated receptor-gamma via the JNK-dependent pathway. 2004 Exp. Cell Res. pmid:15212945
Mantel A et al. Aldo-keto reductase 1C3 is overexpressed in skin squamous cell carcinoma (SCC) and affects SCC growth via prostaglandin metabolism. 2014 Exp. Dermatol. pmid:24917395
Jeon KI et al. Inhibitory effects of PPARγ ligands on TGF-β1-induced CTGF expression in cat corneal fibroblasts. 2015 Exp. Eye Res. pmid:26142957
Kuriyan AE et al. Electrophilic PPARγ ligands inhibit corneal fibroblast to myofibroblast differentiation in vitro: a potentially novel therapy for corneal scarring. 2012 Exp. Eye Res. pmid:22178289
Nencioni A et al. Cyclopentenone prostaglandins induce caspase activation and apoptosis in dendritic cells by a PPAR-gamma-independent mechanism: regulation by inflammatory and T cell-derived stimuli. 2002 Exp. Hematol. pmid:12225793
Kanbe E et al. DR1-like element in human topoisomerase IIalpha gene involved in enhancement of etoposide-induced apoptosis by PPARgamma ligand. 2003 Exp. Hematol. pmid:12691917
Kim BE et al. Cytochrome C-dependent Fas-independent apoptotic pathway in HeLa cells induced by delta12-prostaglandin J2. 2003 Exp. Mol. Med. pmid:14508070
Lee KJ et al. Ox-LDL suppresses PMA-induced MMP-9 expression and activity through CD36-mediated activation of PPAR-g. 2004 Exp. Mol. Med. pmid:15665586
Kim HJ et al. 15-Deoxy-delta12,14-PGJ2 inhibits IL-6-induced Stat3 phosphorylation in lymphocytes. 2005 Exp. Mol. Med. pmid:16000871
Zhang HX et al. Alteration of biochemical and pathological properties of TDP-43 protein by a lipid mediator, 15-deoxy-Delta(12,14)-prostaglandin J(2). 2010 Exp. Neurol. pmid:20083106
Muñoz U et al. The cyclopentenone 15-deoxy-delta(12,14)-prostaglandin J2 inhibits G1/S transition and retinoblastoma protein phosphorylation in immortalized lymphocytes from Alzheimer's disease patients. 2005 Exp. Neurol. pmid:16061222
Lotz C et al. Peroxisome-proliferator-activated receptor γ mediates the second window of anaesthetic-induced preconditioning. 2011 Exp. Physiol. pmid:21123361
Okada M et al. Peroxisome proliferator-activated receptor-gamma (PPAR-gamma) activation suppresses ischemic induction of Egr-1 and its inflammatory gene targets. 2002 FASEB J. pmid:12468449
Wayman NS et al. Ligands of the peroxisome proliferator-activated receptors (PPAR-gamma and PPAR-alpha) reduce myocardial infarct size. 2002 FASEB J. pmid:12087064
Kalantari P et al. 15-Deoxy-Delta12,14-prostaglandin J2 inhibits HIV-1 transactivating protein, Tat, through covalent modification. 2009 FASEB J. pmid:19299483
Planagumà A et al. The selective cyclooxygenase-2 inhibitor SC-236 reduces liver fibrosis by mechanisms involving non-parenchymal cell apoptosis and PPARgamma activation. 2005 FASEB J. pmid:15876570
Gilroy DW et al. Inducible cyclooxygenase-derived 15-deoxy(Delta)12-14PGJ2 brings about acute inflammatory resolution in rat pleurisy by inducing neutrophil and macrophage apoptosis. 2003 FASEB J. pmid:14563690
Zernecke A et al. Suppression of endothelial adhesion molecule up-regulation with cyclopentenone prostaglandins is dissociated from IkappaB-alpha kinase inhibition and cell death induction. 2003 FASEB J. pmid:12692090
Coyle AT et al. 15-deoxy Delta12,14-prostaglandin J2 suppresses transcription by promoter 3 of the human thromboxane A2 receptor gene through peroxisome proliferator-activated receptor gamma in human erythroleukemia cells. 2005 FEBS J. pmid:16156795
Mazid MA et al. Endogenous 15-deoxy-Delta(12,14)-prostaglandin J(2) synthesized by adipocytes during maturation phase contributes to upregulation of fat storage. 2006 FEBS Lett. pmid:17150216
Antoun J et al. CYP4A11 is repressed by retinoic acid in human liver cells. 2006 FEBS Lett. pmid:16712844
Faveeuw C et al. Peroxisome proliferator-activated receptor gamma activators inhibit interleukin-12 production in murine dendritic cells. 2000 FEBS Lett. pmid:11119715
Gayarre J et al. Differential selectivity of protein modification by the cyclopentenone prostaglandins PGA1 and 15-deoxy-Delta12,14-PGJ2: role of glutathione. 2005 FEBS Lett. pmid:16223487
Na HK et al. ET-18-O-CH3-induced apoptosis is causally linked to COX-2 upregulation in H-ras transformed human breast epithelial cells. 2005 FEBS Lett. pmid:16253239
Sugiyama H et al. Peroxisome proliferator-activated receptors are expressed in mouse bone marrow-derived mast cells. 2000 FEBS Lett. pmid:10675550
Waku T et al. Atomic structure of mutant PPARgamma LBD complexed with 15d-PGJ2: novel modulation mechanism of PPARgamma/RXRalpha function by covalently bound ligands. 2009 FEBS Lett. pmid:19101554
Boyault S et al. 15-Deoxy-delta(12,14)-prostaglandin J(2) inhibits IL-1beta-induced IKK enzymatic activity and IkappaBalpha degradation in rat chondrocytes through a PPARgamma-independent pathway. 2004 FEBS Lett. pmid:15304320
Hong HY et al. Up-regulation of heme oxygenase-1 expression through the Rac1/NADPH oxidase/ROS/p38 signaling cascade mediates the anti-inflammatory effect of 15-deoxy-delta 12,14-prostaglandin J2 in murine macrophages. 2008 FEBS Lett. pmid:18291107
Boyault S et al. 15-Deoxy-delta12,14-PGJ2, but not troglitazone, modulates IL-1beta effects in human chondrocytes by inhibiting NF-kappaB and AP-1 activation pathways. 2001 FEBS Lett. pmid:11457450
Pritts EA et al. Peroxisome proliferator-activated receptor-gamma ligand inhibition of RANTES production by human endometriotic stromal cells is mediated through an upstream promoter element. 2003 Fertil. Steril. pmid:12909507
Wanichkul T et al. Cytokine regulation by peroxisome proliferator-activated receptor gamma in human endometrial cells. 2003 Fertil. Steril. pmid:12620489
Kim YS et al. Distinct protective mechanisms of HO-1 and HO-2 against hydroperoxide-induced cytotoxicity. 2005 Free Radic. Biol. Med. pmid:15589375
Cerbone A et al. 4-Hydroxynonenal and PPARgamma ligands affect proliferation, differentiation, and apoptosis in colon cancer cells. 2007 Free Radic. Biol. Med. pmid:17462534
Higdon AN et al. Methods for imaging and detecting modification of proteins by reactive lipid species. 2009 Free Radic. Biol. Med. pmid:19446632
Brechbuhl HM et al. Select cyclopentenone prostaglandins trigger glutathione efflux and the role of ABCG2 transport. 2009 Free Radic. Biol. Med. pmid:19520157
Lee E et al. 15-Deoxy-Δ12,14-prostaglandin J₂ modulates manganese-induced activation of the NF-κB, Nrf2, and PI3K pathways in astrocytes. 2012 Free Radic. Biol. Med. pmid:22245093
Kansanen E et al. Regulation of Nrf2-dependent gene expression by 15-deoxy-Delta12,14-prostaglandin J2. 2009 Free Radic. Biol. Med. pmid:19573595
Lin YC et al. The glutathionylation of p65 modulates NF-κB activity in 15-deoxy-Δ¹²,¹⁴-prostaglandin J₂-treated endothelial cells. 2012 Free Radic. Biol. Med. pmid:22387200
Kang ES et al. 15-Deoxy-Δ(12,14)-prostaglandin J2 prevents oxidative injury by upregulating the expression of aldose reductase in vascular smooth muscle cells. 2014 Free Radic. Res. pmid:24180671
Li L et al. Heme oxygenase-1 is an antifibrogenic protein in human hepatic myofibroblasts. 2003 Gastroenterology pmid:12891549
Marra F et al. Ligands of peroxisome proliferator-activated receptor gamma modulate profibrogenic and proinflammatory actions in hepatic stellate cells. 2000 Gastroenterology pmid:10930382
Ponferrada A et al. The role of PPARgamma on restoration of colonic homeostasis after experimental stress-induced inflammation and dysfunction. 2007 Gastroenterology pmid:17484875
Matzkin ME et al. Exploring the cyclooxygenase 2 (COX2)/15d-Δ(12,14)PGJ(2) system in hamster Sertoli cells: regulation by FSH/testosterone and relevance to glucose uptake. 2012 Gen. Comp. Endocrinol. pmid:22974512
Tsujita T et al. Nitro-fatty acids and cyclopentenone prostaglandins share strategies to activate the Keap1-Nrf2 system: a study using green fluorescent protein transgenic zebrafish. 2011 Genes Cells pmid:21143560
Kobayashi M et al. ATM activation by a sulfhydryl-reactive inflammatory cyclopentenone prostaglandin. 2006 Genes Cells pmid:16824197
Urahama N et al. The role of transcriptional coactivator TRAP220 in myelomonocytic differentiation. 2005 Genes Cells pmid:16324150
Natarajan C and Bright JJ Peroxisome proliferator-activated receptor-gamma agonists inhibit experimental allergic encephalomyelitis by blocking IL-12 production, IL-12 signaling and Th1 differentiation. 2002 Genes Immun. pmid:11960303
Li XY et al. 15-Deoxy-prostaglandin J2 anti-inflammation in a rat model of chronic obstructive pulmonary disease and human bronchial epithelial cells via Nrf2 activation. 2015 Genet. Mol. Res. pmid:26535717
Kerr BJ et al. The protective effects of 15-deoxy-delta-(12,14)-prostaglandin J2 in spinal cord injury. 2008 Glia pmid:18205174
Shimada T et al. Characteristics of the peroxisome proliferator activated receptor gamma (PPARgamma) ligand induced apoptosis in colon cancer cells. 2002 Gut pmid:11950812
Leung WK et al. Effect of peroxisome proliferator activated receptor gamma ligands on growth and gene expression profiles of gastric cancer cells. 2004 Gut pmid:14960510
Yuan Z et al. Cardioprotective effects of peroxisome proliferator activated receptor gamma activators on acute myocarditis: anti-inflammatory actions associated with nuclear factor kappaB blockade. 2005 Heart pmid:15774612
Galli A et al. Peroxisome proliferator-activated receptor gamma transcriptional regulation is involved in platelet-derived growth factor-induced proliferation of human hepatic stellate cells. 2000 Hepatology pmid:10613734
Copple IM et al. The hepatotoxic metabolite of acetaminophen directly activates the Keap1-Nrf2 cell defense system. 2008 Hepatology pmid:18785192
Kuboki S et al. Peroxisome proliferator-activated receptor-gamma protects against hepatic ischemia/reperfusion injury in mice. 2008 Hepatology pmid:18085707
Mendez M and LaPointe MC PPARgamma inhibition of cyclooxygenase-2, PGE2 synthase, and inducible nitric oxide synthase in cardiac myocytes. 2003 Hypertension pmid:12885795
Katsumata Y et al. Endogenous prostaglandin D2 and its metabolites protect the heart against ischemia-reperfusion injury by activating Nrf2. 2014 Hypertension pmid:24101662
Ikeda U et al. Peroxisome proliferator-activated receptor-gamma ligands inhibit nitric oxide synthesis in vascular smooth muscle cells. 2000 Hypertension pmid:10856269
Kim HY and Kim HS Upregulation of MIP-2 (CXCL2) expression by 15-deoxy-Delta(12,14)-prostaglandin J(2) in mouse peritoneal macrophages. 2007 Immunol. Cell Biol. pmid:17130903
Imaizumi T et al. 15-Deoxy-D12,14-prostaglandin J2 inhibits CX3CL1/fractalkine expression in human endothelial cells. 2002 Immunol. Cell Biol. pmid:12406386
Kim HY et al. Upregulation of LPS-induced chemokine KC expression by 15-deoxy-delta12,14-prostaglandin J2 in mouse peritoneal macrophages. 2005 Immunol. Cell Biol. pmid:15877607
Harris SG and Phipps RP Prostaglandin D(2), its metabolite 15-d-PGJ(2), and peroxisome proliferator activated receptor-gamma agonists induce apoptosis in transformed, but not normal, human T lineage cells. 2002 Immunology pmid:11849312
Sykes L et al. The CRTH2 agonist Pyl A prevents lipopolysaccharide-induced fetal death but induces preterm labour. 2013 Immunology pmid:23374103
Han S and Sidell N Peroxisome-proliferator-activated-receptor gamma (PPARgamma) independent induction of CD36 in THP-1 monocytes by retinoic acid. 2002 Immunology pmid:11972632
Arnold R et al. Peroxisome proliferator-activated receptor-gamma agonists inhibit respiratory syncytial virus-induced expression of intercellular adhesion molecule-1 in human lung epithelial cells. 2007 Immunology pmid:17425601
Miyawaki T et al. Combination of midazolam and a cyclooxygenase-2 inhibitor inhibits lipopolysaccharide-induced interleukin-6 production in human peripheral blood mononuclear cells. 2012 Immunopharmacol Immunotoxicol pmid:21854184
Sánchez-Gómez FJ et al. Modulation of GSTP1-1 oligomerization by electrophilic inflammatory mediators and reactive drugs. 2013 Inflamm Allergy Drug Targets pmid:23596995
Martínez AE et al. 15-Deoxy-Δ(12,14)-prostaglandin J2 exerts pro- and anti-inflammatory effects in mesangial cells in a concentration-dependent manner. 2012 Inflamm Allergy Drug Targets pmid:22309084
Fernandez-Bustamante A et al. Early increase in alveolar macrophage prostaglandin 15d-PGJ2 precedes neutrophil recruitment into lungs of cytokine-insufflated rats. 2013 Inflammation pmid:23616184
Hashimoto K et al. Peroxisome proliferator-activated receptor gamma ligand inhibits cell growth and invasion of human pancreatic cancer cells. 2002 Int J Gastrointest Cancer pmid:12630765
Fujita M et al. Cytotoxicity of 15-deoxy-Δ(12,14)-prostaglandin J(2) through PPARγ-independent pathway and the involvement of the JNK and Akt pathway in renal cell carcinoma. 2012 Int J Med Sci pmid:22991494
Abbasi S et al. Elimination of the biphasic pharmacodynamics of 15d-PGJ2 by controlling its release from a nanoemulsion. 2016 Int J Nanomedicine pmid:27354798
Ueki S et al. Anti- and proinflammatory effects of 15-deoxy-delta-prostaglandin J2(15d-PGJ2) on human eosinophil functions. 2007 Int. Arch. Allergy Immunol. pmid:17541271
Chiba T et al. 15-Deoxy-Delta(12,14)-prostaglandin J2 induces IL-8 and GM-CSF in a human airway epithelial cell line (NCI-H292). 2009 Int. Arch. Allergy Immunol. pmid:19494510
Imaizumi T et al. 15-deoxy-delta(12,14)-prostaglandin J2 inhibits IFN-gamma-induced galectin-9 expression in cultured human umbilical vein endothelial cells. 2003 Int. Arch. Allergy Immunol. pmid:12759491
Zhang M et al. Curcumin inhibits trinitrobenzene sulphonic acid-induced colitis in rats by activation of peroxisome proliferator-activated receptor gamma. 2006 Int. Immunopharmacol. pmid:16782535
Napimoga MH et al. Low doses of 15d-PGJ2 induce osteoblast activity in a PPAR-gamma independent manner. 2013 Int. Immunopharmacol. pmid:23597428
Kanunfre CC et al. Ciglitizone and 15d PGJ2 induce apoptosis in Jurkat and Raji cells. 2004 Int. Immunopharmacol. pmid:15251113
Wu P et al. Inflammation pro-resolving potential of 3,4-dihydroxyacetophenone through 15-deoxy-delta12,14-prostaglandin J2 in murine macrophages. 2007 Int. Immunopharmacol. pmid:17761349
Chou YH et al. The possible role of heat shock factor-1 in the negative regulation of heme oxygenase-1. 2005 Int. J. Biochem. Cell Biol. pmid:15618017
Yu JH et al. SOCS 3 and PPAR-gamma ligands inhibit the expression of IL-6 and TGF-beta1 by regulating JAK2/STAT3 signaling in pancreas. 2008 Int. J. Biochem. Cell Biol. pmid:18035585
Winnett G et al. Prostaglandin J2 metabolites inhibit aromatase activity by redox-sensitive mechanisms: potential implications for breast cancer therapy. 2003 Int. J. Cancer pmid:12494466
Badawi AF and Badr MZ Expression of cyclooxygenase-2 and peroxisome proliferator-activated receptor-gamma and levels of prostaglandin E2 and 15-deoxy-delta12,14-prostaglandin J2 in human breast cancer and metastasis. 2003 Int. J. Cancer pmid:12455057
Koyani CN et al. 15-deoxy-Δ¹²,¹⁴-PGJ₂ promotes inflammation and apoptosis in cardiomyocytes via the DP2/MAPK/TNFα axis. 2014 Int. J. Cardiol. pmid:24698234
Tsujimoto S et al. Nimesulide, a cyclooxygenase-2 selective inhibitor, suppresses obesity-related non-alcoholic fatty liver disease and hepatic insulin resistance through the regulation of peroxisome proliferator-activated receptor γ. 2016 Int. J. Mol. Med. pmid:27431935
Li H and Narahara H 15-Deoxy-Δ(12,14)-prostaglandin J(2) induces growth inhibition, cell cycle arrest and apoptosis in human endometrial cancer cell lines. 2013 Int. J. Mol. Med. pmid:23403520
Da Silva Morais A et al. Peroxisome proliferated-activated receptor gamma ligand, Pioglitazone, does not prevent hepatic fibrosis in mice. 2007 Int. J. Mol. Med. pmid:17143554
Jung WK et al. The 15-deoxy-δ12,14-prostaglandin J2 inhibits LPS‑stimulated inflammation via enhancement of the platelet‑activating factor acetylhydrolase activity in human retinal pigment epithelial cells. 2014 Int. J. Mol. Med. pmid:24337644
Yoshimura R et al. The effect of peroxisome proliferator-activated receptor-gamma ligand on urological cancer cells. 2003 Int. J. Mol. Med. pmid:14612958
Okano H et al. The PPARgamma ligand, 15-Deoxy-Delta12,14-PGJ2, regulates apoptosis-related protein expression in cholangio cell carcinoma cells. 2003 Int. J. Mol. Med. pmid:14612959
Moriai M et al. Down-regulation of hTERT expression plays an important role in 15-deoxy-Delta12,14-prostaglandin J2-induced apoptosis in cancer cells. 2009 Int. J. Oncol. pmid:19360348
Haslmayer P et al. The peroxisome proliferator-activated receptor gamma ligand 15-deoxy-Delta12,14-prostaglandin J2 induces vascular endothelial growth factor in the hormone-independent prostate cancer cell line PC 3 and the urinary bladder carcinoma cell line 5637. 2002 Int. J. Oncol. pmid:12239635
Matsuzaki Y et al. 15-deoxy-Delta12, 14-prostaglandin J2 activates the expression of p15INK4b gene, a cyclin-dependent kinase inhibitor. 2005 Int. J. Oncol. pmid:16010433
Morosetti R et al. The PPARgamma ligands PGJ2 and rosiglitazone show a differential ability to inhibit proliferation and to induce apoptosis and differentiation of human glioblastoma cell lines. 2004 Int. J. Oncol. pmid:15254749
Shim J et al. The peroxisome proliferator-activated receptor gamma ligands, pioglitazone and 15-deoxy-Delta(12,14)-prostaglandin J(2), have antineoplastic effects against hepatitis B virus-associated hepatocellular carcinoma cells. 2010 Int. J. Oncol. pmid:19956851
Cekanova M et al. Gene alterations by peroxisome proliferator-activated receptor gamma agonists in human colorectal cancer cells. 2008 Int. J. Oncol. pmid:18360708
Takashima T et al. PPAR-gamma ligands inhibit growth of human esophageal adenocarcinoma cells through induction of apoptosis, cell cycle arrest and reduction of ornithine decarboxylase activity. 2001 Int. J. Oncol. pmid:11494023
Marshall JC Modeling MODS: what can be learned from animal models of the multiple-organ dysfunction syndrome? 2005 Intensive Care Med pmid:15782317
Hauser B et al. Effects of 15-deoxy-Delta12,14-prostaglandin-J2 during hyperdynamic porcine endotoxemia. 2006 Intensive Care Med pmid:16534570
Marzocco S et al. The cyclopentenone prostaglandin 15-deoxydelta(12,14)-prostaglandin J2 attenuates the development of zymosan-induced shock. 2005 Intensive Care Med pmid:15868139