| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hyperalgesia | D006930 | 42 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Parkinson Disease | D010300 | 53 associated lipids |
| Weight Loss | D015431 | 56 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Liver Cirrhosis | D008103 | 67 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Carcinoma, Non-Small-Cell Lung | D002289 | 72 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
15-deoxy-delta-12,14-PGJ2
15-deoxy-delta-12,14-pgj2 is a lipid of Fatty Acyls (FA) class. 15-deoxy-delta-12,14-pgj2 is associated with abnormalities such as Dehydration and Myocardial Ischemia. The involved functions are known as Binding (Molecular Function), Inflammation, Alveolar ventilation function, Stimulus and Process. 15-deoxy-delta-12,14-pgj2 often locates in Cytosol, Myocardial tissue and Heart tissue. The associated genes with 15-deoxy-delta-12,14-PGJ2 are Homologous Gene and G-substrate. The related lipids are 15-deoxyprostaglandin J2 and Lipopolysaccharides.
Cross Reference
Introduction
To understand associated biological information of 15-deoxy-delta-12,14-PGJ2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 15-deoxy-delta-12,14-PGJ2?
15-deoxy-delta-12,14-PGJ2 is suspected in Dehydration, Myocardial Ischemia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 15-deoxy-delta-12,14-PGJ2
PubChem Associated disorders and diseases
What pathways are associated with 15-deoxy-delta-12,14-PGJ2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 15-deoxy-delta-12,14-PGJ2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 15-deoxy-delta-12,14-PGJ2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 15-deoxy-delta-12,14-PGJ2?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with 15-deoxy-delta-12,14-PGJ2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 15-deoxy-delta-12,14-PGJ2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 15-deoxy-delta-12,14-PGJ2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Huang L et al. | 15d-PGJ2 Reduced Microglia Activation and Alleviated Neurological Deficit of Ischemic Reperfusion in Diabetic Rat Model. | 2015 | Biomed Res Int | pmid:26844229 |
| Li P et al. | [Effect of peroxisome proliferator-activated receptor-γ on endothelial cells oxidative stress induced by Porphyromonas gingivalis]. | 2015 | Beijing Da Xue Xue Bao | pmid:26679661 |
| Li XY et al. | 15-Deoxy-prostaglandin J2 anti-inflammation in a rat model of chronic obstructive pulmonary disease and human bronchial epithelial cells via Nrf2 activation. | 2015 | Genet. Mol. Res. | pmid:26535717 |
| Xu X et al. | Effect of Salusin-β on Peroxisome Proliferator-Activated Receptor Gamma Gene Expression in Vascular Smooth Muscle Cells and its Possible Mechanism. | 2015 | Cell. Physiol. Biochem. | pmid:26279448 |
| Gao D et al. | Rosiglitzone suppresses angiotensin II-induced production of KLF5 and cell proliferation in rat vascular smooth muscle cells. | 2015 | PLoS ONE | pmid:25874449 |
| Maier NK et al. | The cyclopentenone prostaglandin 15d-PGJ2 inhibits the NLRP1 and NLRP3 inflammasomes. | 2015 | J. Immunol. | pmid:25681332 |
| Wall SB et al. | Rac1 modification by an electrophilic 15-deoxy Δ(12,14)-prostaglandin J2 analog. | 2015 | Redox Biol | pmid:25677088 |
| Meng Y et al. | Angiotensin II-induced Egr-1 expression is suppressed by peroxisome proliferator-activated receptor-γ ligand 15d-PGJ₂ in macrophages. | 2015 | Cell. Physiol. Biochem. | pmid:25591955 |
| Penas F et al. | Treatment in vitro with PPARα and PPARγ ligands drives M1-to-M2 polarization of macrophages from T. cruzi-infected mice. | 2015 | Biochim. Biophys. Acta | pmid:25557389 |
| Hyun J et al. | Human intestinal epithelial cells express interleukin-10 through Toll-like receptor 4-mediated epithelial-macrophage crosstalk. | 2015 | J Innate Immun | pmid:25171731 |
| Fang M et al. | Activation of Human Peroxisome Proliferator-Activated Nuclear Receptors (PPARγ1) by Semi-Volatile Compounds (SVOCs) and Chemical Mixtures in Indoor Dust. | 2015 | Environ. Sci. Technol. | pmid:26172262 |
| Kim KR et al. | 15-deoxy-δ12,14-prostaglandin j2 inhibits osteolytic breast cancer bone metastasis and estrogen deficiency-induced bone loss. | 2015 | PLoS ONE | pmid:25859665 |
| Korolczuk A et al. | The role of peroxisome-proliferator-activating receptor gamma agonists: rosiglitazone and 15-deoxy-delta12,14-prostaglandin J2 in chronic experimental cyclosporine A-induced nephrotoxicity. | 2014 | J. Physiol. Pharmacol. | pmid:25554991 |
| Korbecki J et al. | Cyclooxygenase pathways. | 2014 | Acta Biochim. Pol. | pmid:25343148 |
| Savinainen JR et al. | Biochemical and pharmacological characterization of the human lymphocyte antigen B-associated transcript 5 (BAT5/ABHD16A). | 2014 | PLoS ONE | pmid:25290914 |
| Paakinaho V et al. | Electrophilic lipid mediator 15-deoxy-Δ12,14-prostaglandin j2 modifies glucocorticoid signaling via receptor SUMOylation. | 2014 | Mol. Cell. Biol. | pmid:24980431 |
| Liu C et al. | 15d-PGJâ‚‚ decreases PGEâ‚‚ synthesis in HBx-positive liver cells by interfering EGR1 binding to mPGES-1 promoter. | 2014 | Biochem. Pharmacol. | pmid:25108236 |
| Kumar AP et al. | Manganese superoxide dismutase is a promising target for enhancing chemosensitivity of basal-like breast carcinoma. | 2014 | Antioxid. Redox Signal. | pmid:23964924 |
| Yin Y et al. | PPARγ agonists regulate tobacco smoke-induced Toll like receptor 4 expression in alveolar macrophages. | 2014 | Respir. Res. | pmid:24612634 |
| Heiss EH et al. | Identification of chromomoric acid C-I as an Nrf2 activator in Chromolaena odorata. | 2014 | J. Nat. Prod. | pmid:24476568 |