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Biphasic effects of 15-deoxy-delta(12,14)-prostaglandin J(2) on glutathione induction and apoptosis in human endothelial cells. |
2001 |
Arterioscler. Thromb. Vasc. Biol. |
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Peroxisome proliferator-activated receptor-gamma activity is associated with renal microvasculature. |
2001 |
Am. J. Physiol. Renal Physiol. |
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Expression of adipogenesis markers in a murine stromal cell line treated with 15-deoxy Delta(12,14)-prostaglandin J2, interleukin-11, 9-cis retinoic acid and vitamin K2. |
2001 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:11728175
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Stimulated release of arachidonic acid by agonists of the peroxisome proliferator-activated receptor and retinoic acid receptors. |
2001 |
Prostaglandins Leukot. Essent. Fatty Acids |
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Pignatelli M et al. |
The peroxisome proliferator-activated receptor gamma is an inhibitor of ErbBs activity in human breast cancer cells. |
2001 |
J. Cell. Sci. |
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Unique ability of troglitazone to up-regulate peroxisome proliferator-activated receptor-gamma expression in hepatocytes. |
2002 |
J. Pharmacol. Exp. Ther. |
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Upregulation of interleukin-8 expression by prostaglandin D2 metabolite 15-deoxy-delta12, 14 prostaglandin J2 (15d-PGJ2) in human THP-1 macrophages. |
2002 |
Atherosclerosis |
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15-deoxy-delta12,14-prostaglandin J2-induced apoptosis in amnion-like WISH cells. |
2001 |
Prostaglandins Other Lipid Mediat. |
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15-deoxy-delta 12,14-prostaglandin J2. A prostaglandin D2 metabolite generated during inflammatory processes. |
2002 |
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15-deoxy-Delta 12,14-PGJ2 induces IL-8 production in human T cells by a mitogen-activated protein kinase pathway. |
2002 |
J. Immunol. |
pmid:11801678
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Regulation of prostaglandin endoperoxide synthase-2 and IL-6 expression in mouse bone marrow-derived mast cells by exogenous but not endogenous prostanoids. |
2002 |
J. Immunol. |
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Kalajdzic T et al. |
Nimesulide, a preferential cyclooxygenase 2 inhibitor, suppresses peroxisome proliferator-activated receptor induction of cyclooxygenase 2 gene expression in human synovial fibroblasts: evidence for receptor antagonism. |
2002 |
Arthritis Rheum. |
pmid:11840453
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Harris SG and Phipps RP |
Prostaglandin D(2), its metabolite 15-d-PGJ(2), and peroxisome proliferator activated receptor-gamma agonists induce apoptosis in transformed, but not normal, human T lineage cells. |
2002 |
Immunology |
pmid:11849312
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Masamune A et al. |
Ligands of peroxisome proliferator-activated receptor-gamma induce apoptosis in AR42J cells. |
2002 |
Pancreas |
pmid:11854617
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Peroxisome proliferator-activated receptor-gamma agonist 15-deoxy-Delta(12,14)-prostaglandin J(2) ameliorates experimental autoimmune encephalomyelitis. |
2002 |
J. Immunol. |
pmid:11859145
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Prostaglandins as modulators of immunity. |
2002 |
Trends Immunol. |
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Streptozotocin-pancreatic damage in the rat: modulatory effect of 15-deoxy delta12,14-prostaglandin j(2) on nitridergic and prostanoid pathway. |
2002 |
Nitric Oxide |
pmid:11890746
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Monneret G et al. |
15-Deoxy-delta 12,14-prostaglandins D2 and J2 are potent activators of human eosinophils. |
2002 |
J. Immunol. |
pmid:11907120
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15-Deoxy-Delta12,14-prostaglandin J2 regulates mesangial cell proliferation and death. |
2002 |
Kidney Int. |
pmid:11918736
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Quraishi O et al. |
Inhibition of inducible prostaglandin E(2) synthase by 15-deoxy-Delta(12,14)-prostaglandin J(2) and polyunsaturated fatty acids. |
2002 |
Biochem. Pharmacol. |
pmid:11931852
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Hong JT et al. |
Inhibitory effect of peroxisome proliferator-activated receptor gamma agonist on ochratoxin A-induced cytotoxicity and activation of transcription factors in cultured rat embryonic midbrain cells. |
2002 |
J. Toxicol. Environ. Health Part A |
pmid:11936221
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Shimada T et al. |
Characteristics of the peroxisome proliferator activated receptor gamma (PPARgamma) ligand induced apoptosis in colon cancer cells. |
2002 |
Gut |
pmid:11950812
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Natural ligands of PPARgamma: are prostaglandin J(2) derivatives really playing the part? |
2002 |
Cell. Signal. |
pmid:11955950
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Finck BN and Johnson RW |
Anti-inflammatory agents inhibit the induction of leptin by tumor necrosis factor-alpha. |
2002 |
Am. J. Physiol. Regul. Integr. Comp. Physiol. |
pmid:11959686
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Natarajan C and Bright JJ |
Peroxisome proliferator-activated receptor-gamma agonists inhibit experimental allergic encephalomyelitis by blocking IL-12 production, IL-12 signaling and Th1 differentiation. |
2002 |
Genes Immun. |
pmid:11960303
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The cyclopentenone prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J(2) attenuates the development of acute and chronic inflammation. |
2002 |
Mol. Pharmacol. |
pmid:11961117
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Kojima K et al. |
Effect of PPARgamma ligands on the viability of gastric epithelial cells. |
2002 |
Aliment. Pharmacol. Ther. |
pmid:11966526
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Selective inhibition of cyclooxygenase-2 expression by 15-deoxy-Delta(12,14)(12,14)-prostaglandin J(2) in activated human astrocytes, but not in human brain macrophages. |
2002 |
J. Immunol. |
pmid:11971025
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Han S and Sidell N |
Peroxisome-proliferator-activated-receptor gamma (PPARgamma) independent induction of CD36 in THP-1 monocytes by retinoic acid. |
2002 |
Immunology |
pmid:11972632
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Padilla J et al. |
Human B lymphocytes and B lymphomas express PPAR-gamma and are killed by PPAR-gamma agonists. |
2002 |
Clin. Immunol. |
pmid:11987982
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A proinflammatory role for the cyclopentenone prostaglandins at low micromolar concentrations: oxidative stress-induced extracellular signal-regulated kinase activation without NF-kappa B inhibition. |
2002 |
J. Immunol. |
pmid:11994490
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Activation of the mouse heme oxygenase-1 gene by 15-deoxy-Delta(12,14)-prostaglandin J(2) is mediated by the stress response elements and transcription factor Nrf2. |
2002 |
Antioxid. Redox Signal. |
pmid:12006176
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Yu Y et al. |
Conjugated linoleic acid decreases production of pro-inflammatory products in macrophages: evidence for a PPAR gamma-dependent mechanism. |
2002 |
Biochim. Biophys. Acta |
pmid:12020636
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Lecka-Czernik B et al. |
Divergent effects of selective peroxisome proliferator-activated receptor-gamma 2 ligands on adipocyte versus osteoblast differentiation. |
2002 |
Endocrinology |
pmid:12021203
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Sawano H et al. |
15-Deoxy-Delta12,14-prostaglandin J2 inhibits IL-1beta-induced cyclooxygenase-2 expression in mesangial cells. |
2002 |
Kidney Int. |
pmid:12028436
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Kim EJ et al. |
Effects of peroxisome proliferator-activated receptor agonists on LPS-induced neuronal death in mixed cortical neurons: associated with iNOS and COX-2. |
2002 |
Brain Res. |
pmid:12031542
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15-Deoxy-Delta(12,14)-prostaglandin J(2): the endogenous electrophile that induces neuronal apoptosis. |
2002 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12032289
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MAP kinase cascades are activated in astrocytes and preadipocytes by 15-deoxy-Delta(12-14)-prostaglandin J(2) and the thiazolidinedione ciglitazone through peroxisome proliferator activator receptor gamma-independent mechanisms involving reactive oxygenated species. |
2002 |
J. Biol. Chem. |
pmid:12052825
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Ward C et al. |
Prostaglandin D2 and its metabolites induce caspase-dependent granulocyte apoptosis that is mediated via inhibition of I kappa B alpha degradation using a peroxisome proliferator-activated receptor-gamma-independent mechanism. |
2002 |
J. Immunol. |
pmid:12055237
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Yamazaki R et al. |
Nonsteroidal anti-inflammatory drugs induce apoptosis in association with activation of peroxisome proliferator-activated receptor gamma in rheumatoid synovial cells. |
2002 |
J. Pharmacol. Exp. Ther. |
pmid:12065695
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Huang WC et al. |
Superoxide anion-dependent Raf/MEK/ERK activation by peroxisome proliferator activated receptor gamma agonists 15-deoxy-delta(12,14)-prostaglandin J(2), ciglitazone, and GW1929. |
2002 |
Exp. Cell Res. |
pmid:12083801
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Wayman NS et al. |
Ligands of the peroxisome proliferator-activated receptors (PPAR-gamma and PPAR-alpha) reduce myocardial infarct size. |
2002 |
FASEB J. |
pmid:12087064
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Miyazaki Y et al. |
Inhibitory effect of peroxisome proliferator-activated receptor-gamma ligands on the expression of IgE heavy chain germline transcripts in the human B cell line DND39. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:12150985
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Chen SY et al. |
15-Deoxy-delta12,14-prostaglandin J2 induces apoptosis of a thyroid papillary cancer cell line (CG3 cells) through increasing intracellular iron and oxidative stress. |
2002 |
Anticancer Drugs |
pmid:12187333
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Nencioni A et al. |
Cyclopentenone prostaglandins induce caspase activation and apoptosis in dendritic cells by a PPAR-gamma-independent mechanism: regulation by inflammatory and T cell-derived stimuli. |
2002 |
Exp. Hematol. |
pmid:12225793
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Mössner R et al. |
Agonists of peroxisome proliferator-activated receptor gamma inhibit cell growth in malignant melanoma. |
2002 |
J. Invest. Dermatol. |
pmid:12230498
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Haslmayer P et al. |
The peroxisome proliferator-activated receptor gamma ligand 15-deoxy-Delta12,14-prostaglandin J2 induces vascular endothelial growth factor in the hormone-independent prostate cancer cell line PC 3 and the urinary bladder carcinoma cell line 5637. |
2002 |
Int. J. Oncol. |
pmid:12239635
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Eligini S et al. |
15-deoxy-delta12,14-Prostaglandin J2 inhibits tissue factor expression in human macrophages and endothelial cells: evidence for ERK1/2 signaling pathway blockade. |
2002 |
Thromb. Haemost. |
pmid:12353085
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Campo PA et al. |
Translational regulation of cyclin D1 by 15-deoxy-delta(12,14)-prostaglandin J(2). |
2002 |
Cell Growth Differ. |
pmid:12354750
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Lappas M et al. |
Regulation of proinflammatory cytokines in human gestational tissues by peroxisome proliferator-activated receptor-gamma: effect of 15-deoxy-Delta(12,14)-PGJ(2) and troglitazone. |
2002 |
J. Clin. Endocrinol. Metab. |
pmid:12364456
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