Kim DH et al. |
15-Deoxy-Delta(12,14)-prostaglandin J(2) stabilizes, but functionally inactivates p53 by binding to the cysteine 277 residue. |
2010 |
Oncogene |
pmid:20208557
|
Kim YI et al. |
Effects of 15-deoxy-∆¹²,¹â´-prostaglandin Jâ‚‚ on the production of IL-8 and the expression of Toll-like receptor 2 in human primary keratinocytes stimulated with lipopolysaccharide. |
2011 |
Mol. Biol. Rep. |
pmid:20174873
|
Zhu F et al. |
Prostaglandin (PG)D(2) and 15-deoxy-Delta(12,14)-PGJ(2), but not PGE(2), mediate shear-induced chondrocyte apoptosis via protein kinase A-dependent regulation of polo-like kinases. |
2010 |
Cell Death Differ. |
pmid:20150912
|
Dionne S et al. |
PPARgamma ligand 15-deoxy-delta 12,14-prostaglandin J2 sensitizes human colon carcinoma cells to TWEAK-induced apoptosis. |
2010 |
Anticancer Res. |
pmid:20150631
|
Schell C et al. |
15-Deoxy-delta 12-14-prostaglandin-J2 induces hypertrophy and loss of contractility in human testicular peritubular cells: implications for human male fertility. |
2010 |
Endocrinology |
pmid:20133451
|
Poncin S et al. |
Oxidative stress: a required condition for thyroid cell proliferation. |
2010 |
Am. J. Pathol. |
pmid:20093493
|
Katura T et al. |
15-Deoxy-delta 12,14-prostaglandin J2 biphasically regulates the proliferation of mouse hippocampal neural progenitor cells by modulating the redox state. |
2010 |
Mol. Pharmacol. |
pmid:20086036
|
Zhang HX et al. |
Alteration of biochemical and pathological properties of TDP-43 protein by a lipid mediator, 15-deoxy-Delta(12,14)-prostaglandin J(2). |
2010 |
Exp. Neurol. |
pmid:20083106
|
Bancos S et al. |
Induction of heme oxygenase-1 in normal and malignant B lymphocytes by 15-deoxy-Delta(12,14)-prostaglandin J(2) requires Nrf2. |
2010 |
Cell. Immunol. |
pmid:20064636
|
Watanabe K et al. |
15-deoxy-delta 12,14-prostaglandin J2 prevents inflammatory response and endothelial cell damage in rats with acute obstructive cholangitis. |
2010 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:20056897
|
Moraes LA et al. |
Non-genomic effects of PPARgamma ligands: inhibition of GPVI-stimulated platelet activation. |
2010 |
J. Thromb. Haemost. |
pmid:20040043
|
Byrns MC et al. |
Aldo-keto reductase 1C3 expression in MCF-7 cells reveals roles in steroid hormone and prostaglandin metabolism that may explain its over-expression in breast cancer. |
2010 |
J. Steroid Biochem. Mol. Biol. |
pmid:20036328
|
Zorrilla S et al. |
Selective binding of the fluorescent dye 1-anilinonaphthalene-8-sulfonic acid to peroxisome proliferator-activated receptor gamma allows ligand identification and characterization. |
2010 |
Anal. Biochem. |
pmid:20025845
|
Lin TH et al. |
Upregulation of heme oxygenase-1 inhibits the maturation and mineralization of osteoblasts. |
2010 |
J. Cell. Physiol. |
pmid:20020468
|
Prakash J et al. |
Albumin-binding and tumor vasculature determine the antitumor effect of 15-deoxy-Delta-(12,14)-prostaglandin-J(2) in vivo. |
2009 |
Neoplasia |
pmid:20019843
|
Khanim FL et al. |
Combined bezafibrate and medroxyprogesterone acetate: potential novel therapy for acute myeloid leukaemia. |
2009 |
PLoS ONE |
pmid:19997560
|
Hovsepian E et al. |
15-deoxy-Delta12,14 prostaglandin GJ2 but not rosiglitazone regulates metalloproteinase 9, NOS-2, and cyclooxygenase 2 expression and functions by peroxisome proliferator-activated receptor gamma-dependent and -independent mechanisms in cardiac cells. |
2010 |
Shock |
pmid:19997048
|
Shim J et al. |
The peroxisome proliferator-activated receptor gamma ligands, pioglitazone and 15-deoxy-Delta(12,14)-prostaglandin J(2), have antineoplastic effects against hepatitis B virus-associated hepatocellular carcinoma cells. |
2010 |
Int. J. Oncol. |
pmid:19956851
|
Théoleyre S et al. |
HtrA3 is regulated by 15-deoxy-Delta12,14-prostaglandin J2 independently of PPARgamma in clear cell renal cell carcinomas. |
2010 |
Biochem. Biophys. Res. Commun. |
pmid:19951697
|
Zhang F et al. |
Peroxisome proliferator-activated receptor-gamma agonists suppress iNOS expression induced by LPS in rat primary Schwann cells. |
2010 |
J. Neuroimmunol. |
pmid:19942298
|
Mo C et al. |
PPARgamma regulates LIF-induced growth and self-renewal of mouse ES cells through Tyk2-Stat3 pathway. |
2010 |
Cell. Signal. |
pmid:19922793
|
Diers AR et al. |
Mitochondrial targeting of the electrophilic lipid 15-deoxy-Delta12,14-prostaglandin J2 increases apoptotic efficacy via redox cell signalling mechanisms. |
2010 |
Biochem. J. |
pmid:19916962
|
Toaldo C et al. |
PPARgamma ligands inhibit telomerase activity and hTERT expression through modulation of the Myc/Mad/Max network in colon cancer cells. |
2010 |
J. Cell. Mol. Med. |
pmid:19912441
|
Morgenweck J et al. |
Activation of peroxisome proliferator-activated receptor gamma in brain inhibits inflammatory pain, dorsal horn expression of Fos, and local edema. |
2010 |
Neuropharmacology |
pmid:19891980
|
Li H and Pauza CD |
Effects of 15-deoxy-delta12,14-prostaglandin J2 (15d-PGJ2) and rosiglitazone on human gammadelta2 T cells. |
2009 |
PLoS ONE |
pmid:19888466
|
Xue J et al. |
Aspirin inhibits MMP-9 mRNA expression and release via the PPARalpha/gamma and COX-2/mPGES-1-mediated pathways in macrophages derived from THP-1 cells. |
2010 |
Biomed. Pharmacother. |
pmid:19880272
|
Landrier JF et al. |
Adiponectin expression is induced by vitamin E via a peroxisome proliferator-activated receptor gamma-dependent mechanism. |
2009 |
Endocrinology |
pmid:19833717
|
Pustovrh MC et al. |
MMP/ TIMP balance is modulated in vitro by 15dPGJ(2) in fetuses and placentas from diabetic rats. |
2009 |
Eur. J. Clin. Invest. |
pmid:19811527
|
Hironaka A et al. |
15-Deoxy-Delta(12,14)-prostaglandin J(2) impairs the functions of histone acetyltransferases through their insolubilization in cells. |
2009 |
Biochem. Biophys. Res. Commun. |
pmid:19799872
|
Pacienza N et al. |
15-deoxy-Delta(12,14)-PGJ(2) induces cell cycle arrest and apoptosis of haematopoietic progenitors. |
2010 |
Br. J. Haematol. |
pmid:19764987
|
Ferguson HE et al. |
Peroxisome proliferator-activated receptor-gamma ligands induce heme oxygenase-1 in lung fibroblasts by a PPARgamma-independent, glutathione-dependent mechanism. |
2009 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:19734319
|
Cha B et al. |
15-Deoxy-delta 12, 14,-prostaglandin J2 suppresses nuclear factor-kappaB-mediated apoptosis of Helicobacter pylori-infected gastric epithelial cells. |
2009 |
Ann. N. Y. Acad. Sci. |
pmid:19723089
|
Song NY et al. |
15-Deoxy-delta 12, 14-prostaglandin J2 induces upregulation of multidrug resistance-associated protein 1 via Nrf2 activation in human breast cancer cells. |
2009 |
Ann. N. Y. Acad. Sci. |
pmid:19723058
|
Kim DH et al. |
Effects of 15-deoxy-delta 12, 14-prostaglandin J2 on the expression of p53 in MCF-7 cells. |
2009 |
Ann. N. Y. Acad. Sci. |
pmid:19723057
|
Ma XM et al. |
Peroxisome proliferator-activated receptor-gamma is essential in the pathogenesis of gastric carcinoma. |
2009 |
World J. Gastroenterol. |
pmid:19701967
|
Shin SW et al. |
15d-PGJ2 induces apoptosis by reactive oxygen species-mediated inactivation of Akt in leukemia and colorectal cancer cells and shows in vivo antitumor activity. |
2009 |
Clin. Cancer Res. |
pmid:19690198
|
Pena-dos-Santos DR et al. |
Activation of peripheral kappa/delta opioid receptors mediates 15-deoxy-(Delta12,14)-prostaglandin J2 induced-antinociception in rat temporomandibular joint. |
2009 |
Neuroscience |
pmid:19647045
|
Cocca C et al. |
15-Deoxi-Delta(12,14)-prostaglandin J2 is a tubulin-binding agent that destabilizes microtubules and induces mitotic arrest. |
2009 |
Biochem. Pharmacol. |
pmid:19576185
|
Kansanen E et al. |
Regulation of Nrf2-dependent gene expression by 15-deoxy-Delta12,14-prostaglandin J2. |
2009 |
Free Radic. Biol. Med. |
pmid:19573595
|
Qin HD et al. |
Upregulation of peroxisome proliferator-activated receptor-gamma and NADPH oxidases are involved in restenosis after balloon injury. |
2009 |
J. Cell. Physiol. |
pmid:19562688
|
Tsutsui C et al. |
Peperomins as anti-inflammatory agents that inhibit the NF-kappaB signaling pathway. |
2009 |
Bioorg. Med. Chem. Lett. |
pmid:19559609
|
Comabella M et al. |
Plasma levels of 15d-PGJ are not altered in multiple sclerosis. |
2009 |
Eur. J. Neurol. |
pmid:19538219
|
Bernardo A et al. |
Peroxisome proliferator-activated receptor-gamma agonists promote differentiation and antioxidant defenses of oligodendrocyte progenitor cells. |
2009 |
J. Neuropathol. Exp. Neurol. |
pmid:19535992
|
Ramji DP |
Growth hormone-releasing peptides, CD36, and stimulation of cholesterol efflux: cyclooxygenase-2 is the link. |
2009 |
Cardiovasc. Res. |
pmid:19520704
|
Brechbuhl HM et al. |
Select cyclopentenone prostaglandins trigger glutathione efflux and the role of ABCG2 transport. |
2009 |
Free Radic. Biol. Med. |
pmid:19520157
|
Chiba T et al. |
15-Deoxy-Delta(12,14)-prostaglandin J2 induces IL-8 and GM-CSF in a human airway epithelial cell line (NCI-H292). |
2009 |
Int. Arch. Allergy Immunol. |
pmid:19494510
|
Wang X et al. |
Potential effects of peroxisome proliferator-activated receptor activator on LPS-induced lung injury in rats. |
2009 |
Pulm Pharmacol Ther |
pmid:19489131
|
Zhang GY et al. |
Activation of peroxisome proliferator-activated receptor-gamma inhibits transforming growth factor-beta1 induction of connective tissue growth factor and extracellular matrix in hypertrophic scar fibroblasts in vitro. |
2009 |
Arch. Dermatol. Res. |
pmid:19466435
|
Olmos G et al. |
15-Deoxy-Delta(12,14)-prostaglandin-J(2) reveals a new pVHL-independent, lysosomal-dependent mechanism of HIF-1alpha degradation. |
2009 |
Cell. Mol. Life Sci. |
pmid:19458911
|
Kar R et al. |
A novel role for MAP1 LC3 in nonautophagic cytoplasmic vacuolation death of cancer cells. |
2009 |
Oncogene |
pmid:19448671
|