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Ligands for peroxisome proliferator-activated receptor gamma have potent antitumor effect against human renal cell carcinoma. |
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Urology |
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2005 |
Intensive Care Med |
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2005 |
Rheumatology (Oxford) |
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2005 |
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Peroxisome proliferator-activated receptor-gamma agonists inhibit the activation of microglia and astrocytes: implications for multiple sclerosis. |
2005 |
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Aspirin increases CD36, SR-BI, and ABCA1 expression in human THP-1 macrophages. |
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Effects of 15-deoxy-delta(12,14)-prostaglandin J2 on nuclear localization of GATA-3 in the murine lung in the presence of lipopolysaccharide. |
2005 |
Arzneimittelforschung |
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2005 |
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15-deoxy Delta12,14-prostaglandin J2 suppresses transcription by promoter 3 of the human thromboxane A2 receptor gene through peroxisome proliferator-activated receptor gamma in human erythroleukemia cells. |
2005 |
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5-Oxo-ETE analogs and the proliferation of cancer cells. |
2005 |
Biochim. Biophys. Acta |
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Peroxynitrites and impaired modulation of nitric oxide concentrations in embryos from diabetic rats during early organogenesis. |
2005 |
Reproduction |
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2005 |
Toxicology |
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2005 |
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ET-18-O-CH3-induced apoptosis is causally linked to COX-2 upregulation in H-ras transformed human breast epithelial cells. |
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2005 |
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Augmentation of lipogenesis by 15-deoxy-Delta12,14-prostaglandin J2 in hamster sebaceous glands: identification of cytochrome P-450-mediated 15-deoxy-Delta12,14-prostaglandin J2 production. |
2005 |
J. Invest. Dermatol. |
pmid:16297182
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Contrasting effects of peroxisome-proliferator-activated receptor (PPAR)gamma agonists on membrane-associated prostaglandin E2 synthase-1 in IL-1beta-stimulated rat chondrocytes: evidence for PPARgamma-independent inhibition by 15-deoxy-Delta12,14prostaglandin J2. |
2005 |
Arthritis Res. Ther. |
pmid:16277686
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Chen ZY and Tseng CC |
15-deoxy-Delta12,14 prostaglandin J2 up-regulates Kruppel-like factor 4 expression independently of peroxisome proliferator-activated receptor gamma by activating the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase signal transduction pathway in HT-29 colon cancer cells. |
2005 |
Mol. Pharmacol. |
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PPAR-gamma agonists inhibit toll-like receptor-mediated activation of dendritic cells via the MAP kinase and NF-kappaB pathways. |
2005 |
Blood |
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Cyclopentenone prostaglandins PGA2 and 15-deoxy-delta12,14 PGJ2 suppress activation of murine microglia and astrocytes: implications for multiple sclerosis. |
2005 |
J. Neurosci. Res. |
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Aromatase inhibition by 15-deoxy-prostaglandin J(2) (15-dPGJ(2)) and N-(4-hydroxyphenyl)-retinamide (4HPR) is associated with enhanced ceramide production. |
2005 |
J. Steroid Biochem. Mol. Biol. |
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The cyclopentenone prostaglandin 15-deoxydelta(12,14)-prostaglandin J2 attenuates the development of zymosan-induced shock. |
2005 |
Intensive Care Med |
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Expression and regulation of microsomal prostaglandin E synthase-1 in human osteoarthritic cartilage and chondrocytes. |
2005 |
J. Rheumatol. |
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Insulin alters nuclear factor-lambdaB and peroxisome proliferator-activated receptor-gamma protein expression induced by glycated bovine serum albumin in vascular smooth-muscle cells. |
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J. Lab. Clin. Med. |
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The selective cyclooxygenase-2 inhibitor SC-236 reduces liver fibrosis by mechanisms involving non-parenchymal cell apoptosis and PPARgamma activation. |
2005 |
FASEB J. |
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Upregulation of LPS-induced chemokine KC expression by 15-deoxy-delta12,14-prostaglandin J2 in mouse peritoneal macrophages. |
2005 |
Immunol. Cell Biol. |
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Modulation of cytokine-induced cyclooxygenase 2 expression by PPARG ligands through NFkappaB signal disruption in human WISH and amnion cells. |
2005 |
Biol. Reprod. |
pmid:15843495
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Unusual astrocyte reactivity caused by the food mycotoxin ochratoxin A in aggregating rat brain cell cultures. |
2005 |
Neuroscience |
pmid:15994020
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Troglitazone and 15-deoxy-delta(12,14)-prostaglandin J2 inhibit shear-induced coupling factor 6 release in endothelial cells. |
2005 |
Cardiovasc. Res. |
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Expression of PPARgamma and beta/delta in human primary osteoblastic cells: influence of polyunsaturated fatty acids. |
2005 |
Calcif. Tissue Int. |
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Effects of 15-deoxy-Delta12,14-prostaglandin J2 on the expression of Toll-like receptor 4 and 2 in the murine lung in the presence of lipopolysaccharide. |
2005 |
Clin. Exp. Pharmacol. Physiol. |
pmid:15743408
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Lindström TM and Bennett PR |
15-Deoxy-{delta}12,14-prostaglandin j2 inhibits interleukin-1{beta}-induced nuclear factor-{kappa}b in human amnion and myometrial cells: mechanisms and implications. |
2005 |
J. Clin. Endocrinol. Metab. |
pmid:15755849
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Relationship between peroxisome proliferator-activated receptor-gamma expression and differentiation of human esophageal squamous cell carcinoma. |
2005 |
Oncol. Rep. |
pmid:15756430
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Effect of nuclear factor-kappa B inhibitors and peroxisome proliferator-activated receptor-gamma ligands on PTHrP release from human fetal membranes. |
2004 Sep-Oct |
Placenta |
pmid:15450387
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15d-PGJ2 inhibits oxidized LDL-induced macrophage proliferation by inhibition of GM-CSF production via inactivation of NF-kappaB. |
2004 |
Biochem. Biophys. Res. Commun. |
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Opposite effects of prostaglandin-J2 on VEGF in normoxia and hypoxia: role of HIF-1. |
2004 |
Biochem. Biophys. Res. Commun. |
pmid:14715242
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A yeast two-hybrid technology-based system for the discovery of PPARgamma agonist and antagonist. |
2004 |
Anal. Biochem. |
pmid:15556564
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Hypoxia-reoxygenation enhances interleukin-8 production from U937 human monocytic cells. |
2004 |
Redox Rep. |
pmid:15720834
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A PPAR-gamma ligand, 15-deoxy-Delta12,14-prostaglandin J(2), inhibited gastric mucosal injury induced by ischemia-reperfusion in rats. |
2004 |
Redox Rep. |
pmid:15720836
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Grau R et al. |
Inhibition of activator protein 1 activation, vascular endothelial growth factor, and cyclooxygenase-2 expression by 15-deoxy-Delta12,14-prostaglandin J2 in colon carcinoma cells: evidence for a redox-sensitive peroxisome proliferator-activated receptor-gamma-independent mechanism. |
2004 |
Cancer Res. |
pmid:15289320
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Boyault S et al. |
15-Deoxy-delta(12,14)-prostaglandin J(2) inhibits IL-1beta-induced IKK enzymatic activity and IkappaBalpha degradation in rat chondrocytes through a PPARgamma-independent pathway. |
2004 |
FEBS Lett. |
pmid:15304320
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Jawerbaum A et al. |
Influence of peroxisome proliferator-activated receptor gamma activation by its endogenous ligand 15-deoxy Delta12,14 prostaglandin J2 on nitric oxide production in term placental tissues from diabetic women. |
2004 |
Mol. Hum. Reprod. |
pmid:15258247
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Zhao ML et al. |
15-deoxy-delta (12,14)-PGJ2 inhibits astrocyte IL-1 signaling: inhibition of NF-kappaB and MAP kinase pathways and suppression of cytokine and chemokine expression. |
2004 |
J. Neuroimmunol. |
pmid:15265671
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Brummond KM et al. |
The first total synthesis of 15-deoxy-Delta12,14-prostaglandin J2 and the unambiguous assignment of the C14 stereochemistry. |
2004 |
Org. Lett. |
pmid:14723515
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