15-deoxy-delta-12,14-PGJ2

15-deoxy-delta-12,14-pgj2 is a lipid of Fatty Acyls (FA) class. 15-deoxy-delta-12,14-pgj2 is associated with abnormalities such as Dehydration and Myocardial Ischemia. The involved functions are known as Binding (Molecular Function), Inflammation, Alveolar ventilation function, Stimulus and Process. 15-deoxy-delta-12,14-pgj2 often locates in Cytosol, Myocardial tissue and Heart tissue. The associated genes with 15-deoxy-delta-12,14-PGJ2 are Homologous Gene and G-substrate. The related lipids are 15-deoxyprostaglandin J2 and Lipopolysaccharides.

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Introduction

To understand associated biological information of 15-deoxy-delta-12,14-PGJ2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 15-deoxy-delta-12,14-PGJ2?

15-deoxy-delta-12,14-PGJ2 is suspected in Dehydration, Myocardial Ischemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 15-deoxy-delta-12,14-PGJ2

MeSH term MeSH ID Detail
Liver Cirrhosis, Experimental D008106 36 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Lymphoma, B-Cell D016393 24 associated lipids
Fibrosis D005355 23 associated lipids
Myocardial Infarction D009203 21 associated lipids
Lymphoma, T-Cell D016399 11 associated lipids
Goiter D006042 4 associated lipids
Actinobacillus Infections D000189 4 associated lipids
Graves Ophthalmopathy D049970 3 associated lipids
Leukemia, B-Cell D015448 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 15-deoxy-delta-12,14-PGJ2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 15-deoxy-delta-12,14-PGJ2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 15-deoxy-delta-12,14-PGJ2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 15-deoxy-delta-12,14-PGJ2?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 15-deoxy-delta-12,14-PGJ2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 15-deoxy-delta-12,14-PGJ2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 15-deoxy-delta-12,14-PGJ2

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Per page 10 20 50 100 | Total 940
Authors Title Published Journal PubMed Link
Paakinaho V et al. Electrophilic lipid mediator 15-deoxy-Δ12,14-prostaglandin j2 modifies glucocorticoid signaling via receptor SUMOylation. 2014 Mol. Cell. Biol. pmid:24980431
Yen CC et al. Cytotoxic effects of 15d-PGJ2 against osteosarcoma through ROS-mediated AKT and cell cycle inhibition. 2014 Oncotarget pmid:24566468
García-Bueno B et al. Pro-/anti-inflammatory dysregulation in patients with first episode of psychosis: toward an integrative inflammatory hypothesis of schizophrenia. 2014 Schizophr Bull pmid:23486748
Casali CI et al. Coordinate regulation between the nuclear receptor peroxisome proliferator-activated receptor-γ and cyclooxygenase-2 in renal epithelial cells. 2014 Biochem. Pharmacol. pmid:24915420
Tachi M et al. Mass spectrometric determination of prostanoids in rat hypothalamic paraventricular nucleus microdialysates. 2014 Auton Neurosci pmid:24447364
Kurtz M et al. Peroxisome proliferator-activated receptor ligands regulate lipid content, metabolism, and composition in fetal lungs of diabetic rats. 2014 J. Endocrinol. pmid:24389592
Chen S et al. 15-Deoxy-Δ(12,14)-prostaglandin J2 (15d-PGJ2) promotes apoptosis of HBx-positive liver cells. 2014 Chem. Biol. Interact. pmid:24582817
Bogacka I et al. The involvement of peroxisome proliferator activated receptors (PPARs) in prostaglandin F2α production by porcine endometrium. 2013 Reprod Biol pmid:24287039
Yaacob NS et al. Influence of 17β-estradiol on 15-deoxy-δ12,14 prostaglandin J2 -induced apoptosis in MCF-7 and MDA-MB-231 cells. 2013 Asian Pac. J. Cancer Prev. pmid:24377602
Zerani M et al. Evidence for a luteotropic role of peroxisome proliferator-activated receptor gamma: expression and in vitro effects on enzymatic and hormonal activities in corpora lutea of pseudopregnant rabbits. 2013 Biol. Reprod. pmid:23365414