Mendez M and LaPointe MC |
PPARgamma inhibition of cyclooxygenase-2, PGE2 synthase, and inducible nitric oxide synthase in cardiac myocytes. |
2003 |
Hypertension |
pmid:12885795
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Chen CW et al. |
Inhibition of IFN-gamma-mediated inducible nitric oxide synthase induction by the peroxisome proliferator-activated receptor gamma agonist, 15-deoxy-delta 12,14-prostaglandin J2, involves inhibition of the upstream Janus kinase/STAT1 signaling pathway. |
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J. Immunol. |
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Peroxisome proliferator-activated receptor ligands affect growth-related gene expression in human leukemic cells. |
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J. Pharmacol. Exp. Ther. |
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Regulation of retinoic acid receptor beta expression by peroxisome proliferator-activated receptor gamma ligands in cancer cells. |
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Cancer Res. |
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Liver Int. |
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Houston KD et al. |
Inhibition of proliferation and estrogen receptor signaling by peroxisome proliferator-activated receptor gamma ligands in uterine leiomyoma. |
2003 |
Cancer Res. |
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Peroxisome proliferator-activated receptor gamma ligands attenuate immunological symptoms of experimental allergic asthma. |
2003 |
Arch. Biochem. Biophys. |
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Cytochrome C-dependent Fas-independent apoptotic pathway in HeLa cells induced by delta12-prostaglandin J2. |
2003 |
Exp. Mol. Med. |
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15-deoxy-delta 12,14-prostaglandin J2 and laminar fluid shear stress stabilize c-IAP1 in vascular endothelial cells. |
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Am. J. Physiol. Heart Circ. Physiol. |
pmid:12623786
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Fukuchi K et al. |
Apoptosis in human oral squamous cell carcinomas is induced by 15-deoxy-delta 12,14-prostaglandin J2 but not by troglitazone. |
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J. Dent. Res. |
pmid:14514760
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Imaizumi T et al. |
15-Deoxy-delta 12,14-prostaglandin J2 inhibits the expression of granulocyte-macrophage colony-stimulating factor in endothelial cells stimulated with lipopolysaccharide. |
2003 |
Prostaglandins Other Lipid Mediat. |
pmid:14518569
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Chung SW et al. |
Inhibition of interleukin-4 production in CD4+ T cells by peroxisome proliferator-activated receptor-gamma (PPAR-gamma) ligands: involvement of physical association between PPAR-gamma and the nuclear factor of activated T cells transcription factor. |
2003 |
Mol. Pharmacol. |
pmid:14573767
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15-Deoxy-Delta(12,14)-prostaglandin J2 induces apoptosis through activation of the CHOP gene in HeLa cells. |
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Biochem. Biophys. Res. Commun. |
pmid:14575689
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Effects of peroxisome proliferator-activated receptor gamma ligands ciglitazone and 15-deoxy-delta 12,14-prostaglandin J2 on rat cultured cerebellar granule neuronal viability. |
2003 |
J. Neurosci. Res. |
pmid:12774315
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Armoni M et al. |
Peroxisome proliferator-activated receptor-gamma represses GLUT4 promoter activity in primary adipocytes, and rosiglitazone alleviates this effect. |
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J. Biol. Chem. |
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2003 |
Thromb. Res. |
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Peroxisome proliferator-activated receptor-gamma activator 15-deoxy-Delta12,14-prostaglandin J2 inhibits neuroblastoma cell growth through induction of apoptosis: association with extracellular signal-regulated kinase signal pathway. |
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J. Pharmacol. Exp. Ther. |
pmid:12966153
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Collin M and Thiemermann C |
The PPAR-gamma ligand 15-deoxy(delta12,14) prostaglandin J2 reduces the liver injury in endotoxic shock. |
2003 |
Eur. J. Pharmacol. |
pmid:12969773
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Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2, ligands of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma), reduce ischaemia/reperfusion injury of the gut. |
2003 |
Br. J. Pharmacol. |
pmid:12970094
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15-Deoxy-Delta12,14-prostaglandin J2 regulates endogenous Cot MAPK kinase kinase 1 activity induced by lipopolysaccharide. |
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J. Biol. Chem. |
pmid:14557273
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Selective activation of PPARgamma inhibits pancreatic cancer invasion and decreases expression of tissue plasminogen activator. |
2003 |
Surgery |
pmid:12947319
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15-Deoxy-delta12,14-PGJ2: endogenous PPARgamma ligand or minor eicosanoid degradation product? |
2003 |
J. Clin. Invest. |
pmid:12975467
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15d-PGJ2 inhibits cell growth and induces apoptosis of MCG-803 human gastric cancer cell line. |
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World J. Gastroenterol. |
pmid:14562367
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Biosynthesis of 15-deoxy-delta12,14-PGJ2 and the ligation of PPARgamma. |
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J. Clin. Invest. |
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Inducible cyclooxygenase-derived 15-deoxy(Delta)12-14PGJ2 brings about acute inflammatory resolution in rat pleurisy by inducing neutrophil and macrophage apoptosis. |
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FASEB J. |
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15-deoxy-delta-12-14-PGJ2 regulates apoptosis induction and nuclear factor-kappaB activation via a peroxisome proliferator-activated receptor-gamma-independent mechanism in hepatocellular carcinoma. |
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Lab. Invest. |
pmid:14563954
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DR1-like element in human topoisomerase IIalpha gene involved in enhancement of etoposide-induced apoptosis by PPARgamma ligand. |
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Exp. Hematol. |
pmid:12691917
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Expression of the murine glutathione S-transferase alpha3 (GSTA3) subunit is markedly induced during adipocyte differentiation: activation of the GSTA3 gene promoter by the pro-adipogenic eicosanoid 15-deoxy-Delta12,14-prostaglandin J2. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:14652005
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Suppression of endothelial adhesion molecule up-regulation with cyclopentenone prostaglandins is dissociated from IkappaB-alpha kinase inhibition and cell death induction. |
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FASEB J. |
pmid:12692090
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Garg TK and Chang JY |
Oxidative stress causes ERK phosphorylation and cell death in cultured retinal pigment epithelium: prevention of cell death by AG126 and 15-deoxy-delta 12, 14-PGJ2. |
2003 |
BMC Ophthalmol |
pmid:12659653
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Pérez-Sala D et al. |
Molecular basis for the direct inhibition of AP-1 DNA binding by 15-deoxy-Delta 12,14-prostaglandin J2. |
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J. Biol. Chem. |
pmid:14532268
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[Effects of peroxisome proliferator-activated receptor-gamma agonist on Fas-mediated apoptosis in HT-29 cells]. |
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Korean J Gastroenterol |
pmid:14532729
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Metalloproteinase expression in PMA-stimulated THP-1 cells. Effects of peroxisome proliferator-activated receptor-gamma (PPAR gamma) agonists and 9-cis-retinoic acid. |
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J. Biol. Chem. |
pmid:14534304
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15-deoxy-delta12,14-prostaglandin J2 regulates the functional state and the survival of microglial cells through multiple molecular mechanisms. |
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J. Neurochem. |
pmid:14535956
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Castaño E and Gil J |
15-deoxy-delta12,14 prostaglandin J2 synergizes with phorbol ester to induce proliferation in Swiss 3T3 cells independently of peroxisome proliferator-activated receptor gamma and PGD2 receptors. |
2003 |
J. Cell. Physiol. |
pmid:12704651
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Imaizumi T et al. |
Effect of 15-deoxy-delta12,14-prostaglandin J2 on IL-1beta-induced expression of epithelial neutrophil-activating protein-78 in human endothelial cells. |
2003 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:14580366
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Cippitelli M et al. |
The cyclopentenone-type prostaglandin 15-deoxy-delta 12,14-prostaglandin J2 inhibits CD95 ligand gene expression in T lymphocytes: interference with promoter activation via peroxisome proliferator-activated receptor-gamma-independent mechanisms. |
2003 |
J. Immunol. |
pmid:12707336
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Prostaglandin D2 inhibits the production of interleukin-12 in murine dendritic cells through multiple signaling pathways. |
2003 |
Eur. J. Immunol. |
pmid:12672054
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Takata K et al. |
Possible involvement of small oligomers of amyloid-beta peptides in 15-deoxy-delta 12,14 prostaglandin J2-sensitive microglial activation. |
2003 |
J. Pharmacol. Sci. |
pmid:12719662
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Involvement of c-jun N-terminal kinase activation in 15-deoxy-delta12,14-prostaglandin J2-and prostaglandin A1-induced apoptosis in AGS gastric epithelial cells. |
2003 |
Mol. Carcinog. |
pmid:12720296
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Hata AN et al. |
Expression and molecular pharmacology of the mouse CRTH2 receptor. |
2003 |
J. Pharmacol. Exp. Ther. |
pmid:12721327
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The antiproliferative effects of PPARgamma ligands in normal human mammary epithelial cells. |
2003 |
Breast Cancer Res. Treat. |
pmid:12725418
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The cyclopentenone 15-deoxy-delta 12,14-prostaglandin J2 binds to and activates H-Ras. |
2003 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12684535
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Paumi CM et al. |
Multidrug resistance protein (MRP) 1 and MRP3 attenuate cytotoxic and transactivating effects of the cyclopentenone prostaglandin, 15-deoxy-Delta(12,14)prostaglandin J2 in MCF7 breast cancer cells. |
2003 |
Biochemistry |
pmid:12731885
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Prostaglandin D2 affects the maturation of human monocyte-derived dendritic cells: consequence on the polarization of naive Th cells. |
2003 |
J. Immunol. |
pmid:12734337
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Imaizumi T et al. |
15-deoxy-delta(12,14)-prostaglandin J2 inhibits IFN-gamma-induced galectin-9 expression in cultured human umbilical vein endothelial cells. |
2003 |
Int. Arch. Allergy Immunol. |
pmid:12759491
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Thioredoxin as a molecular target of cyclopentenone prostaglandins. |
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J. Biol. Chem. |
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Activation-induced PPARgamma expression sensitizes primary human T cells toward apoptosis. |
2003 |
J. Leukoc. Biol. |
pmid:12714582
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Park EJ et al. |
15d-PGJ2 and rosiglitazone suppress Janus kinase-STAT inflammatory signaling through induction of suppressor of cytokine signaling 1 (SOCS1) and SOCS3 in glia. |
2003 |
J. Biol. Chem. |
pmid:12584205
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Hinz B et al. |
15-Deoxy-Delta(12,14)-prostaglandin J2 inhibits the expression of proinflammatory genes in human blood monocytes via a PPAR-gamma-independent mechanism. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:12604364
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