| MeSH term | MeSH ID | Detail |
|---|---|---|
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Parkinson Disease | D010300 | 53 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Weight Loss | D015431 | 56 associated lipids |
| Leukemia, B-Cell | D015448 | 3 associated lipids |
| Lymphoma, B-Cell | D016393 | 24 associated lipids |
| Lymphoma, T-Cell | D016399 | 11 associated lipids |
| Graves Ophthalmopathy | D049970 | 3 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
15-deoxy-delta-12,14-PGJ2
15-deoxy-delta-12,14-pgj2 is a lipid of Fatty Acyls (FA) class. 15-deoxy-delta-12,14-pgj2 is associated with abnormalities such as Dehydration and Myocardial Ischemia. The involved functions are known as Binding (Molecular Function), Inflammation, Alveolar ventilation function, Stimulus and Process. 15-deoxy-delta-12,14-pgj2 often locates in Cytosol, Myocardial tissue and Heart tissue. The associated genes with 15-deoxy-delta-12,14-PGJ2 are Homologous Gene and G-substrate. The related lipids are 15-deoxyprostaglandin J2 and Lipopolysaccharides.
Cross Reference
Introduction
To understand associated biological information of 15-deoxy-delta-12,14-PGJ2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 15-deoxy-delta-12,14-PGJ2?
15-deoxy-delta-12,14-PGJ2 is suspected in Dehydration, Myocardial Ischemia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 15-deoxy-delta-12,14-PGJ2
PubChem Associated disorders and diseases
What pathways are associated with 15-deoxy-delta-12,14-PGJ2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 15-deoxy-delta-12,14-PGJ2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 15-deoxy-delta-12,14-PGJ2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 15-deoxy-delta-12,14-PGJ2?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with 15-deoxy-delta-12,14-PGJ2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 15-deoxy-delta-12,14-PGJ2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 15-deoxy-delta-12,14-PGJ2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kasim-Karakas SE et al. | Metabolic and endocrine effects of a polyunsaturated fatty acid-rich diet in polycystic ovary syndrome. | 2004 | J. Clin. Endocrinol. Metab. | pmid:14764771 |
| Matsuo T et al. | 15d-PGJ2 inhibits oxidized LDL-induced macrophage proliferation by inhibition of GM-CSF production via inactivation of NF-kappaB. | 2004 | Biochem. Biophys. Res. Commun. | pmid:14741709 |
| Diab A et al. | Ligands for the peroxisome proliferator-activated receptor-gamma and the retinoid X receptor exert additive anti-inflammatory effects on experimental autoimmune encephalomyelitis. | 2004 | J. Neuroimmunol. | pmid:14975592 |
| Sabichi AL et al. | Peroxisome proliferator-activated receptor-gamma suppresses cyclooxygenase-2 expression in human prostate cells. | 2004 | Cancer Epidemiol. Biomarkers Prev. | pmid:15533896 |
| Subbarayan V et al. | Differential peroxisome proliferator-activated receptor-gamma isoform expression and agonist effects in normal and malignant prostate cells. | 2004 | Cancer Epidemiol. Biomarkers Prev. | pmid:15533897 |
| Huang H et al. | Peroxisome proliferator-activated receptor gamma ligands improve the antitumor efficacy of thrombospondin peptide ABT510. | 2004 | Mol. Cancer Res. | pmid:15498928 |
| Asami-Miyagishi R et al. | Expression and function of PPARgamma in rat placental development. | 2004 | Biochem. Biophys. Res. Commun. | pmid:14766236 |
| Higashihara H et al. | Hypoxia-reoxygenation enhances interleukin-8 production from U937 human monocytic cells. | 2004 | Redox Rep. | pmid:15720834 |
| Takagi T et al. | A PPAR-gamma ligand, 15-deoxy-Delta12,14-prostaglandin J(2), inhibited gastric mucosal injury induced by ischemia-reperfusion in rats. | 2004 | Redox Rep. | pmid:15720836 |
| Mix KS et al. | Peroxisome proliferator-activated receptor-gamma-independent repression of collagenase gene expression by 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid and prostaglandin 15-deoxy-delta(12,14) J2: a role for Smad signaling. | 2004 | Mol. Pharmacol. | pmid:14742672 |
| Lee KJ et al. | Ox-LDL suppresses PMA-induced MMP-9 expression and activity through CD36-mediated activation of PPAR-g. | 2004 | Exp. Mol. Med. | pmid:15665586 |
| Ehara N et al. | Activators of PPARgamma antagonize protection of cardiac myocytes by endothelin-1. | 2004 | Biochem. Biophys. Res. Commun. | pmid:15358182 |
| Li L et al. | Molecular mechanisms regulating the antifibrogenic protein heme-oxygenase-1 in human hepatic myofibroblasts. | 2004 | J. Hepatol. | pmid:15336443 |
| Grau R et al. | Inhibition of activator protein 1 activation, vascular endothelial growth factor, and cyclooxygenase-2 expression by 15-deoxy-Delta12,14-prostaglandin J2 in colon carcinoma cells: evidence for a redox-sensitive peroxisome proliferator-activated receptor-gamma-independent mechanism. | 2004 | Cancer Res. | pmid:15289320 |
| Kielian T et al. | S. aureus-dependent microglial activation is selectively attenuated by the cyclopentenone prostaglandin 15-deoxy-Delta12,14- prostaglandin J2 (15d-PGJ2). | 2004 | J. Neurochem. | pmid:15312171 |
| Weber SM et al. | PPARgamma ligands induce ER stress in pancreatic beta-cells: ER stress activation results in attenuation of cytokine signaling. | 2004 | Am. J. Physiol. Endocrinol. Metab. | pmid:15315910 |
| Siavash H et al. | Abrogation of IL-6-mediated JAK signalling by the cyclopentenone prostaglandin 15d-PGJ(2) in oral squamous carcinoma cells. | 2004 | Br. J. Cancer | pmid:15316561 |
| Sánchez-Gómez FJ et al. | Protein thiol modification by 15-deoxy-Delta12,14-prostaglandin J2 addition in mesangial cells: role in the inhibition of pro-inflammatory genes. | 2004 | Mol. Pharmacol. | pmid:15317873 |
| Lim SY et al. | 15-Deoxy-Delta12,14-prostaglandin J(2) protects against nitrosative PC12 cell death through up-regulation of intracellular glutathione synthesis. | 2004 | J. Biol. Chem. | pmid:15319433 |
| Boyault S et al. | 15-Deoxy-delta(12,14)-prostaglandin J(2) inhibits IL-1beta-induced IKK enzymatic activity and IkappaBalpha degradation in rat chondrocytes through a PPARgamma-independent pathway. | 2004 | FEBS Lett. | pmid:15304320 |
| Ichiki T et al. | 15-Deoxy-Delta12,14-prostaglandin J2 and thiazolidinediones transactivate epidermal growth factor and platelet-derived growth factor receptors in vascular smooth muscle cells. | 2004 | Biochem. Biophys. Res. Commun. | pmid:15369766 |
| Si Q et al. | 15-deoxy-Delta12,14-prostaglandin J2 inhibits IFN-inducible protein 10/CXC chemokine ligand 10 expression in human microglia: mechanisms and implications. | 2004 | J. Immunol. | pmid:15322215 |
| Cheng J et al. | Peroxisome proliferator-activated receptor gamma ligands, 15-deoxy-Delta12,14-prostaglandin J2, and ciglitazone, induce growth inhibition and cell cycle arrest in hepatic oval cells. | 2004 | Biochem. Biophys. Res. Commun. | pmid:15325252 |
| Hofnagel O et al. | Proinflammatory cytokines regulate LOX-1 expression in vascular smooth muscle cells. | 2004 | Arterioscler. Thromb. Vasc. Biol. | pmid:15271788 |
| Leung WK et al. | Effect of peroxisome proliferator activated receptor gamma ligands on growth and gene expression profiles of gastric cancer cells. | 2004 | Gut | pmid:14960510 |
| Mouihate A et al. | A novel antipyretic action of 15-deoxy-Delta12,14-prostaglandin J2 in the rat brain. | 2004 | J. Neurosci. | pmid:14960602 |
| Chatterjee PK et al. | The cyclopentenone prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J2 ameliorates ischemic acute renal failure. | 2004 | Cardiovasc. Res. | pmid:14962493 |
| Brummond KM et al. | The first total synthesis of 15-deoxy-Delta12,14-prostaglandin J2 and the unambiguous assignment of the C14 stereochemistry. | 2004 | Org. Lett. | pmid:14723515 |
| Moore RM et al. | Physiological apoptotic agents have different effects upon human amnion epithelial and mesenchymal cells. | 2003 Feb-Mar | Placenta | pmid:12566244 |
| Yuan ZY et al. | [Peroxisome proliferation-activated receptor-gamma ligands ameliorate autoimmune myocarditis associated with inhibition of T cell immunity]. | 2003 | Zhonghua Yi Xue Za Zhi | pmid:14703419 |
| Ceaser EK et al. | Oxidized low-density lipoprotein and 15-deoxy-delta 12,14-PGJ2 increase mitochondrial complex I activity in endothelial cells. | 2003 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12881207 |
| Pritts EA et al. | Peroxisome proliferator-activated receptor-gamma ligand inhibition of RANTES production by human endometriotic stromal cells is mediated through an upstream promoter element. | 2003 | Fertil. Steril. | pmid:12909507 |
| Li L et al. | Heme oxygenase-1 is an antifibrogenic protein in human hepatic myofibroblasts. | 2003 | Gastroenterology | pmid:12891549 |
| Vosseler CA et al. | Structural requirements of cyclopentenone prostaglandins to induce endothelial cell apoptosis. | 2003 | Biochem. Biophys. Res. Commun. | pmid:12859958 |
| Aoun P et al. | Neuroprotective effects of PPARgamma agonists against oxidative insults in HT-22 cells. | 2003 | Eur. J. Pharmacol. | pmid:12860474 |
| Zahradka P et al. | Activation of peroxisome proliferator-activated receptors alpha and gamma1 inhibits human smooth muscle cell proliferation. | 2003 | Mol. Cell. Biochem. | pmid:12841350 |
| Yang L et al. | Peroxisome proliferator-activated receptor gamma and ligands inhibit surfactant protein B gene expression in the lung. | 2003 | J. Biol. Chem. | pmid:12829715 |
| Ianaro A et al. | Anti-inflammatory activity of 15-deoxy-delta12,14-PGJ2 and 2-cyclopenten-1-one: role of the heat shock response. | 2003 | Mol. Pharmacol. | pmid:12815164 |
| Hashimoto K et al. | The PPARgamma ligand, 15d-PGJ2, attenuates the severity of cerulein-induced acute pancreatitis. | 2003 | Pancreas | pmid:12826907 |
| Zingarelli B et al. | Peroxisome proliferator activator receptor-gamma ligands, 15-deoxy-Delta(12,14)-prostaglandin J2 and ciglitazone, reduce systemic inflammation in polymicrobial sepsis by modulation of signal transduction pathways. | 2003 | J. Immunol. | pmid:14662889 |
| Shibata T et al. | An endogenous electrophile that modulates the regulatory mechanism of protein turnover: inhibitory effects of 15-deoxy-Delta 12,14-prostaglandin J2 on proteasome. | 2003 | Biochemistry | pmid:14636064 |
| Inoue K et al. | Effect of 15-deoxy-delta 12,14-prostaglandin J2 on acute lung injury induced by lipopolysaccharide in mice. | 2003 | Eur. J. Pharmacol. | pmid:14642794 |
| Cuzzocrea S et al. | Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2, ligands of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma), reduce ischaemia/reperfusion injury of the gut. | 2003 | Br. J. Pharmacol. | pmid:12970094 |
| Patel HJ et al. | Activation of peroxisome proliferator-activated receptors in human airway smooth muscle cells has a superior anti-inflammatory profile to corticosteroids: relevance for chronic obstructive pulmonary disease therapy. | 2003 | J. Immunol. | pmid:12594295 |
| Cuzzocrea S et al. | The cyclopentenone prostaglandin 15-deoxy-delta(12,14)- PGJ2 attenuates the development of colon injury caused by dinitrobenzene sulphonic acid in the rat. | 2003 | Br. J. Pharmacol. | pmid:12598422 |
| Castrillo A et al. | Potentiation of protein kinase C zeta activity by 15-deoxy-delta(12,14)-prostaglandin J(2) induces an imbalance between mitogen-activated protein kinases and NF-kappa B that promotes apoptosis in macrophages. | 2003 | Mol. Cell. Biol. | pmid:12556480 |
| Jung KM et al. | Activation of p38 mitogen-activated protein kinase and activator protein-1 during the promotion of neurite extension of PC-12 cells by 15-deoxy-delta12,14-prostaglandin J2. | 2003 | Mol. Pharmacol. | pmid:12606768 |
| Abe M et al. | GATA-6 is involved in PPARgamma-mediated activation of differentiated phenotype in human vascular smooth muscle cells. | 2003 | Arterioscler. Thromb. Vasc. Biol. | pmid:12615657 |
| Wanichkul T et al. | Cytokine regulation by peroxisome proliferator-activated receptor gamma in human endometrial cells. | 2003 | Fertil. Steril. | pmid:12620489 |
| Calnek DS et al. | Peroxisome proliferator-activated receptor gamma ligands increase release of nitric oxide from endothelial cells. | 2003 | Arterioscler. Thromb. Vasc. Biol. | pmid:12524224 |