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Peroxisome proliferator-activated receptor-gamma ligands 15-deoxy-delta(12,14)-prostaglandin J2 and pioglitazone inhibit hydroxyl peroxide-induced TNF-alpha and lipopolysaccharide-induced CXC chemokine expression in neonatal rat cardiac myocytes. |
2009 |
Shock |
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Additive inhibitory effect of experimentally induced hepatic cirrhosis by agonists of peroxisome proliferator activator receptor gamma and retinoic acid receptor. |
2009 |
Dig. Dis. Sci. |
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Down-regulation of hTERT expression plays an important role in 15-deoxy-Delta12,14-prostaglandin J2-induced apoptosis in cancer cells. |
2009 |
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Iinuma K et al. |
Involvement of Propionibacterium acnes in the augmentation of lipogenesis in hamster sebaceous glands in vivo and in vitro. |
2009 |
J. Invest. Dermatol. |
pmid:19282842
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Electrophilic peroxisome proliferator-activated receptor-gamma ligands have potent antifibrotic effects in human lung fibroblasts. |
2009 |
Am. J. Respir. Cell Mol. Biol. |
pmid:19286977
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Identification of macrophage inhibitory cytokine-1 in adipose tissue and its secretion as an adipokine by human adipocytes. |
2009 |
Endocrinology |
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CD36-mediated cholesterol efflux is associated with PPARgamma activation via a MAPK-dependent COX-2 pathway in macrophages. |
2009 |
Cardiovasc. Res. |
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Rosiglitazone attenuates insulin-like growth factor 1 receptor survival signaling in PC-3 cells. |
2008 Jul-Aug |
Mol. Med. |
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Hypo-responsiveness of interleukin-8 production in human embryonic epithelial intestine 407 cells independent of NF-kappaB pathway: new lessons from endotoxin and ribotoxic deoxynivalenol. |
2008 |
Toxicol. Appl. Pharmacol. |
pmid:18485432
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Copple IM et al. |
The hepatotoxic metabolite of acetaminophen directly activates the Keap1-Nrf2 cell defense system. |
2008 |
Hepatology |
pmid:18785192
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Oxidative stress in the thyroid gland: from harmlessness to hazard depending on the iodine content. |
2008 |
Endocrinology |
pmid:17884933
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15d-prostaglandin J2 inhibits inflammatory hypernociception: involvement of peripheral opioid receptor. |
2008 |
J. Pharmacol. Exp. Ther. |
pmid:17928570
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Ajulemic acid, a synthetic cannabinoid acid, induces an antiinflammatory profile of eicosanoids in human synovial cells. |
2008 |
Life Sci. |
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Davidson J et al. |
7beta-hydroxy-epiandrosterone modulation of 15-deoxy-delta12,14-prostaglandin J2, prostaglandin D2 and prostaglandin E2 production from human mononuclear cells. |
2008 |
J. Steroid Biochem. Mol. Biol. |
pmid:18996481
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15-Deoxy-delta12,14-prostaglandin-J(2) up-regulates cyclooxygenase-2 but inhibits prostaglandin-E(2) production through a thiol antioxidant-sensitive mechanism. |
2008 |
Pharmacol. Res. |
pmid:18456507
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15-deoxy-Delta12,14-prostaglandin J2 up-regulates death receptor 5 gene expression in HCT116 cells: involvement of reactive oxygen species and C/EBP homologous transcription factor gene transcription. |
2008 |
Mol. Cancer Ther. |
pmid:18852146
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Lee SJ et al. |
15-Deoxy-delta 12,14-prostaglandin J2 induces apoptosis via JNK-mediated mitochondrial pathway in osteoblastic cells. |
2008 |
Toxicology |
pmid:18450357
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Nagata D et al. |
Peroxisome proliferator-activated receptor-gamma and growth inhibition by its ligands in prostate cancer. |
2008 |
Cancer Detect. Prev. |
pmid:18789607
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Chearwae W and Bright JJ |
15-deoxy-Delta(12,14)-prostaglandin J(2) and curcumin modulate the expression of toll-like receptors 4 and 9 in autoimmune T lymphocyte. |
2008 |
J. Clin. Immunol. |
pmid:18463970
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Cutaneous nociception evoked by 15-delta PGJ2 via activation of ion channel TRPA1. |
2008 |
Mol Pain |
pmid:18671867
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Oku H and Umino T |
Molecular characterization of peroxisome proliferator-activated receptors (PPARs) and their gene expression in the differentiating adipocytes of red sea bream Pagrus major. |
2008 |
Comp. Biochem. Physiol. B, Biochem. Mol. Biol. |
pmid:18691667
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15-deoxy-delta 12,14-prostaglandin J(2) inhibits the synthesis of the acute phase protein SIP24 in cartilage: Involvement of COX-2 in resolution of inflammation. |
2008 |
J. Cell. Physiol. |
pmid:18615580
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Effect of cyclopentanone prostaglandin 15-deoxy-delta12,14PGJ2 on early functional recovery from experimental spinal cord injury. |
2008 |
Shock |
pmid:18628687
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Effects of natural ligands of PPARgamma on lipid metabolism in placental tissues from healthy and diabetic rats. |
2008 |
Mol. Hum. Reprod. |
pmid:18621767
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Enhancement of axonal regeneration by in vitro conditioning and its inhibition by cyclopentenone prostaglandins. |
2008 |
J. Cell. Sci. |
pmid:18650498
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Kim EH and Surh YJ |
The role of 15-deoxy-delta(12,14)-prostaglandin J(2), an endogenous ligand of peroxisome proliferator-activated receptor gamma, in tumor angiogenesis. |
2008 |
Biochem. Pharmacol. |
pmid:18771658
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Kim JW et al. |
15-Deoxy-Delta(12,14)-prostaglandin J(2) rescues PC12 cells from H2O2-induced apoptosis through Nrf2-mediated upregulation of heme oxygenase-1: potential roles of Akt and ERK1/2. |
2008 |
Biochem. Pharmacol. |
pmid:18775681
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15-deoxy-Delta(12,14)-prostaglandin J2 induces vascular endothelial cell apoptosis through the sequential activation of MAPKS and p53. |
2008 |
J. Biol. Chem. |
pmid:18718914
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Chearwae W and Bright JJ |
PPARgamma agonists inhibit growth and expansion of CD133+ brain tumour stem cells. |
2008 |
Br. J. Cancer |
pmid:19018263
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Lee JH et al. |
The 15-deoxy-delta 12,14-prostaglandin J2 suppresses monocyte chemoattractant protein-1 expression in IFN-gamma-stimulated astrocytes through induction of MAPK phosphatase-1. |
2008 |
J. Immunol. |
pmid:19050284
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Lian TW et al. |
Fisetin, morin and myricetin attenuate CD36 expression and oxLDL uptake in U937-derived macrophages. |
2008 |
Biochim. Biophys. Acta |
pmid:18662803
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15d-PGJ2 upregulates synthesis of IL-8 in endothelial cells through induction of oxidative stress. |
2008 |
Antioxid. Redox Signal. |
pmid:18665800
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Napimoga MH et al. |
Peroxisome proliferator-activated receptor-gamma ligand, 15-deoxy-Delta12,14-prostaglandin J2, reduces neutrophil migration via a nitric oxide pathway. |
2008 |
J. Immunol. |
pmid:18097063
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Dubourdeau M et al. |
Opposite roles of STAT and PPARgamma in the induction of p21WAF1 expression by IL-13 in human peripheral blood monocytes. |
2008 |
Eur. Cytokine Netw. |
pmid:19103521
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GarcÃa-Bueno B et al. |
Stress mediators regulate brain prostaglandin synthesis and peroxisome proliferator-activated receptor-gamma activation after stress in rats. |
2008 |
Endocrinology |
pmid:18079203
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Muñoz U et al. |
On the mechanism of inhibition of p27 degradation by 15-deoxy-Delta12,14-prostaglandin J2 in lymphoblasts of Alzheimer's disease patients. |
2008 |
Cell. Mol. Life Sci. |
pmid:18818877
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Ferreira-Silva V et al. |
Effects of 15-deoxy-Delta12, 14 prostaglandin J2 and ciglitazone on human cancer cell cycle progression and death: the role of PPARgamma. |
2008 |
Eur. J. Pharmacol. |
pmid:18054911
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Zhang J et al. |
Peroxisome proliferator-activated receptor-gamma agonists attenuate angiotensin II-induced collagen type I expression in adventitial fibroblasts. |
2008 |
Clin. Exp. Pharmacol. Physiol. |
pmid:18047631
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Uchida K and Shibata T |
15-Deoxy-Delta(12,14)-prostaglandin J2: an electrophilic trigger of cellular responses. |
2008 |
Chem. Res. Toxicol. |
pmid:18052108
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Yu JH et al. |
SOCS 3 and PPAR-gamma ligands inhibit the expression of IL-6 and TGF-beta1 by regulating JAK2/STAT3 signaling in pancreas. |
2008 |
Int. J. Biochem. Cell Biol. |
pmid:18035585
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Kuboki S et al. |
Peroxisome proliferator-activated receptor-gamma protects against hepatic ischemia/reperfusion injury in mice. |
2008 |
Hepatology |
pmid:18085707
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Lutzow YS et al. |
15-Deoxy-Delta12,14-prostaglandin J2 induces chemokine expression, oxidative stress and microfilament reorganization in bovine mammary epithelial cells. |
2008 |
J. Dairy Res. |
pmid:18226310
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Kerr BJ et al. |
The protective effects of 15-deoxy-delta-(12,14)-prostaglandin J2 in spinal cord injury. |
2008 |
Glia |
pmid:18205174
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Choi IK et al. |
PPAR-gamma ligand promotes the growth of APC-mutated HT-29 human colon cancer cells in vitro and in vivo. |
2008 |
Invest New Drugs |
pmid:18161004
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Hounoki H et al. |
Activation of peroxisome proliferator-activated receptor gamma inhibits TNF-alpha-mediated osteoclast differentiation in human peripheral monocytes in part via suppression of monocyte chemoattractant protein-1 expression. |
2008 |
Bone |
pmid:18242157
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Kim EH et al. |
15-Deoxy-Delta12,14-prostaglandin J2 induces COX-2 expression through Akt-driven AP-1 activation in human breast cancer cells: a potential role of ROS. |
2008 |
Carcinogenesis |
pmid:18192694
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Crabb SJ et al. |
BAG-1 inhibits PPARgamma-induced cell death, but not PPARgamma-induced transcription, cell cycle arrest or differentiation in breast cancer cells. |
2008 |
Oncol. Rep. |
pmid:18288403
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Hong HY et al. |
Up-regulation of heme oxygenase-1 expression through the Rac1/NADPH oxidase/ROS/p38 signaling cascade mediates the anti-inflammatory effect of 15-deoxy-delta 12,14-prostaglandin J2 in murine macrophages. |
2008 |
FEBS Lett. |
pmid:18291107
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Liu Y et al. |
Increased expression of the peroxisome proliferator-activated receptor gamma in the immune system of weaned pigs after Escherichia coli lipopolysaccharide injection. |
2008 |
Vet. Immunol. Immunopathol. |
pmid:18394717
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Kimura H et al. |
A natural PPAR-gamma agonist, 15-deoxy-delta 12,14-prostaglandin J2, may act as an enhancer of PAI-1 in human proximal renal tubular cells under hypoxic and inflammatory conditions. |
2008 |
Nephrol. Dial. Transplant. |
pmid:18367541
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