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PPAR gamma ligands, 15-deoxy-delta12,14-prostaglandin J2 and rosiglitazone regulate human cultured airway smooth muscle proliferation through different mechanisms. |
2004 |
Br. J. Pharmacol. |
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Effects of 15-deoxy-delta12,14-prostaglandin J2 on the cyclooxygenase-2 expression in the murine lung in the presence of lipopolysaccharide. |
2004 |
Arzneimittelforschung |
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Józkowicz A et al. |
15-deoxy-delta12,14-prostaglandin-J2 inhibits expression of eNOS in human endothelial cells. |
2004 |
Prostaglandins Other Lipid Mediat. |
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Possible involvement of p38 in mechanisms underlying acceleration of proliferation by 15-deoxy-Delta(12,14)-prostaglandin J2 and the precursors in leukemia cell line THP-1. |
2004 |
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Peroxisome proliferator-activated receptor-gamma ligands ameliorate experimental autoimmune myocarditis associated with inhibition of self-sensitive T cells. |
2004 |
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15-deoxy-Delta12,14-prostaglandin J2 inhibits glucocorticoid binding and signaling in macrophages through a peroxisome proliferator-activated receptor gamma-independent process. |
2004 |
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Expression of NAG-1, a transforming growth factor-beta superfamily member, by troglitazone requires the early growth response gene EGR-1. |
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Stress protein activation by the cyclopentenone prostaglandin 15-deoxy-delta12,14-prostaglandin J2 in human mesangial cells. |
2004 |
Kidney Int. |
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PPARgamma ligands attenuate mesangial contractile dysfunction in high glucose. |
2004 |
Kidney Int. |
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Inhibition of rat mammary gland carcinogenesis by simultaneous targeting of cyclooxygenase-2 and peroxisome proliferator-activated receptor gamma. |
2004 |
Cancer Res. |
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2004 |
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Deactivation of murine alveolar macrophages by peroxisome proliferator-activated receptor-gamma ligands. |
2004 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
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Environmental and endogenous peroxisome proliferator-activated receptor gamma agonists induce bone marrow B cell growth arrest and apoptosis: interactions between mono(2-ethylhexyl)phthalate, 9-cis-retinoic acid, and 15-deoxy-Delta12,14-prostaglandin J2. |
2004 |
J. Immunol. |
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Ciglitizone and 15d PGJ2 induce apoptosis in Jurkat and Raji cells. |
2004 |
Int. Immunopharmacol. |
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A potential role of 15-deoxy-delta(12,14)-prostaglandin J2 for induction of human articular chondrocyte apoptosis in arthritis. |
2004 |
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Induction of proliferation by 15-deoxy-delta12,14-prostaglandin J2 and the precursors in monocytic leukemia U937. |
2004 |
Pharmacology |
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The novel synthetic oleanane triterpenoid CDDO (2-cyano-3, 12-dioxoolean-1, 9-dien-28-oic acid) induces apoptosis in Mycosis fungoides/Sézary syndrome cells. |
2004 |
J. Invest. Dermatol. |
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Targeting of epidermal growth factor receptor by cyclopentenone prostaglandin 15-Deoxy-Delta12,14-prostaglandin J2 in human oral squamous carcinoma cells. |
2004 |
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15-deoxy-delta12,14-prostaglandin J2-mediated ERK signaling inhibits gram-negative bacteria-induced RelA phosphorylation and interleukin-6 gene expression in intestinal epithelial cells through modulation of protein phosphatase 2A activity. |
2004 |
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Fenofibrate, troglitazone, and 15-deoxy-Delta12,14-prostaglandin J2 close KATP channels and induce insulin secretion. |
2004 |
J. Pharmacol. Exp. Ther. |
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Involvement of clusterin in 15-deoxy-delta12,14-prostaglandin J2-induced vascular smooth muscle cell differentiation. |
2004 |
Biochem. Biophys. Res. Commun. |
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Differential effects of peroxisome proliferator activated receptor-gamma (PPAR gamma) ligands in proximal tubular cells: thiazolidinediones are partial PPAR gamma agonists. |
2004 |
Kidney Int. |
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Transactivation of the PPAR-responsive enhancer module in chemopreventive glutathione S-transferase gene by the peroxisome proliferator-activated receptor-gamma and retinoid X receptor heterodimer. |
2004 |
Cancer Res. |
pmid:15150131
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Human bone marrow megakaryocytes and platelets express PPARgamma, and PPARgamma agonists blunt platelet release of CD40 ligand and thromboxanes. |
2004 |
Blood |
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Ligands of peroxisome proliferator-activated receptor gamma inhibit lung cancer cell growth and induce apoptosis by stimulation of P21 expression. |
2004 |
Chest |
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PPARgamma agonists ameliorate endothelial cell activation via inhibition of diacylglycerol-protein kinase C signaling pathway: role of diacylglycerol kinase. |
2004 |
Circ. Res. |
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Physiological apoptotic agents have different effects upon human amnion epithelial and mesenchymal cells. |
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Placenta |
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PPARgamma inhibition of cyclooxygenase-2, PGE2 synthase, and inducible nitric oxide synthase in cardiac myocytes. |
2003 |
Hypertension |
pmid:12885795
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Inhibition of IFN-gamma-mediated inducible nitric oxide synthase induction by the peroxisome proliferator-activated receptor gamma agonist, 15-deoxy-delta 12,14-prostaglandin J2, involves inhibition of the upstream Janus kinase/STAT1 signaling pathway. |
2003 |
J. Immunol. |
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Peroxisome proliferator-activated receptor ligands affect growth-related gene expression in human leukemic cells. |
2003 |
J. Pharmacol. Exp. Ther. |
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Regulation of retinoic acid receptor beta expression by peroxisome proliferator-activated receptor gamma ligands in cancer cells. |
2003 |
Cancer Res. |
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15-deoxy-delta 12,14-prostaglandin J2 and laminar fluid shear stress stabilize c-IAP1 in vascular endothelial cells. |
2003 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:12623786
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Inhibition of interleukin-4 production in CD4+ T cells by peroxisome proliferator-activated receptor-gamma (PPAR-gamma) ligands: involvement of physical association between PPAR-gamma and the nuclear factor of activated T cells transcription factor. |
2003 |
Mol. Pharmacol. |
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15-Deoxy-Delta(12,14)-prostaglandin J2 induces apoptosis through activation of the CHOP gene in HeLa cells. |
2003 |
Biochem. Biophys. Res. Commun. |
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Effects of peroxisome proliferator-activated receptor gamma ligands ciglitazone and 15-deoxy-delta 12,14-prostaglandin J2 on rat cultured cerebellar granule neuronal viability. |
2003 |
J. Neurosci. Res. |
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Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2, ligands of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma), reduce ischaemia/reperfusion injury of the gut. |
2003 |
Br. J. Pharmacol. |
pmid:12970094
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15d-PGJ2 inhibits cell growth and induces apoptosis of MCG-803 human gastric cancer cell line. |
2003 |
World J. Gastroenterol. |
pmid:14562367
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Inducible cyclooxygenase-derived 15-deoxy(Delta)12-14PGJ2 brings about acute inflammatory resolution in rat pleurisy by inducing neutrophil and macrophage apoptosis. |
2003 |
FASEB J. |
pmid:14563690
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15-deoxy-delta-12-14-PGJ2 regulates apoptosis induction and nuclear factor-kappaB activation via a peroxisome proliferator-activated receptor-gamma-independent mechanism in hepatocellular carcinoma. |
2003 |
Lab. Invest. |
pmid:14563954
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[Effects of peroxisome proliferator-activated receptor-gamma agonist on Fas-mediated apoptosis in HT-29 cells]. |
2003 |
Korean J Gastroenterol |
pmid:14532729
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Metalloproteinase expression in PMA-stimulated THP-1 cells. Effects of peroxisome proliferator-activated receptor-gamma (PPAR gamma) agonists and 9-cis-retinoic acid. |
2003 |
J. Biol. Chem. |
pmid:14534304
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Effect of 15-deoxy-delta12,14-prostaglandin J2 on IL-1beta-induced expression of epithelial neutrophil-activating protein-78 in human endothelial cells. |
2003 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:14580366
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Liu JD et al. |
Involvement of c-jun N-terminal kinase activation in 15-deoxy-delta12,14-prostaglandin J2-and prostaglandin A1-induced apoptosis in AGS gastric epithelial cells. |
2003 |
Mol. Carcinog. |
pmid:12720296
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Expression and molecular pharmacology of the mouse CRTH2 receptor. |
2003 |
J. Pharmacol. Exp. Ther. |
pmid:12721327
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The antiproliferative effects of PPARgamma ligands in normal human mammary epithelial cells. |
2003 |
Breast Cancer Res. Treat. |
pmid:12725418
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Multidrug resistance protein (MRP) 1 and MRP3 attenuate cytotoxic and transactivating effects of the cyclopentenone prostaglandin, 15-deoxy-Delta(12,14)prostaglandin J2 in MCF7 breast cancer cells. |
2003 |
Biochemistry |
pmid:12731885
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Prostaglandin D2 affects the maturation of human monocyte-derived dendritic cells: consequence on the polarization of naive Th cells. |
2003 |
J. Immunol. |
pmid:12734337
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15-deoxy-delta(12,14)-prostaglandin J2 inhibits IFN-gamma-induced galectin-9 expression in cultured human umbilical vein endothelial cells. |
2003 |
Int. Arch. Allergy Immunol. |
pmid:12759491
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