15-deoxy-delta-12,14-PGJ2

15-deoxy-delta-12,14-pgj2 is a lipid of Fatty Acyls (FA) class. 15-deoxy-delta-12,14-pgj2 is associated with abnormalities such as Dehydration and Myocardial Ischemia. The involved functions are known as Binding (Molecular Function), Inflammation, Alveolar ventilation function, Stimulus and Process. 15-deoxy-delta-12,14-pgj2 often locates in Cytosol, Myocardial tissue and Heart tissue. The associated genes with 15-deoxy-delta-12,14-PGJ2 are Homologous Gene and G-substrate. The related lipids are 15-deoxyprostaglandin J2 and Lipopolysaccharides.

Cross Reference

Introduction

To understand associated biological information of 15-deoxy-delta-12,14-PGJ2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 15-deoxy-delta-12,14-PGJ2?

15-deoxy-delta-12,14-PGJ2 is suspected in Dehydration, Myocardial Ischemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 15-deoxy-delta-12,14-PGJ2

MeSH term MeSH ID Detail
Graves Ophthalmopathy D049970 3 associated lipids
Leukemia, B-Cell D015448 3 associated lipids
Actinobacillus Infections D000189 4 associated lipids
Goiter D006042 4 associated lipids
Lymphoma, T-Cell D016399 11 associated lipids
Myocardial Infarction D009203 21 associated lipids
Fibrosis D005355 23 associated lipids
Lymphoma, B-Cell D016393 24 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Hyperalgesia D006930 42 associated lipids
Thrombosis D013927 49 associated lipids
Parkinson Disease D010300 53 associated lipids
Weight Loss D015431 56 associated lipids
Pain D010146 64 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Colitis D003092 69 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Atherosclerosis D050197 85 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 15-deoxy-delta-12,14-PGJ2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 15-deoxy-delta-12,14-PGJ2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 15-deoxy-delta-12,14-PGJ2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 15-deoxy-delta-12,14-PGJ2?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 15-deoxy-delta-12,14-PGJ2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 15-deoxy-delta-12,14-PGJ2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 15-deoxy-delta-12,14-PGJ2

Download all related citations
Per page 10 20 50 100 | Total 940
Authors Title Published Journal PubMed Link
Levonen AL et al. Biphasic effects of 15-deoxy-delta(12,14)-prostaglandin J(2) on glutathione induction and apoptosis in human endothelial cells. 2001 Arterioscler. Thromb. Vasc. Biol. pmid:11701476
Guan Y et al. Peroxisome proliferator-activated receptor-gamma activity is associated with renal microvasculature. 2001 Am. J. Physiol. Renal Physiol. pmid:11704554
Garcia Palacios V et al. Expression of adipogenesis markers in a murine stromal cell line treated with 15-deoxy Delta(12,14)-prostaglandin J2, interleukin-11, 9-cis retinoic acid and vitamin K2. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11728175
Levine L Stimulated release of arachidonic acid by agonists of the peroxisome proliferator-activated receptor and retinoic acid receptors. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11728177
Pignatelli M et al. The peroxisome proliferator-activated receptor gamma is an inhibitor of ErbBs activity in human breast cancer cells. 2001 J. Cell. Sci. pmid:11739643
Davies GF et al. Unique ability of troglitazone to up-regulate peroxisome proliferator-activated receptor-gamma expression in hepatocytes. 2002 J. Pharmacol. Exp. Ther. pmid:11752099
Fu Y et al. Upregulation of interleukin-8 expression by prostaglandin D2 metabolite 15-deoxy-delta12, 14 prostaglandin J2 (15d-PGJ2) in human THP-1 macrophages. 2002 Atherosclerosis pmid:11755918
Keelan J et al. 15-deoxy-delta12,14-prostaglandin J2-induced apoptosis in amnion-like WISH cells. 2001 Prostaglandins Other Lipid Mediat. pmid:11785780
Shibata T et al. 15-deoxy-delta 12,14-prostaglandin J2. A prostaglandin D2 metabolite generated during inflammatory processes. 2002 J. Biol. Chem. pmid:11786541
Harris SG et al. 15-deoxy-Delta 12,14-PGJ2 induces IL-8 production in human T cells by a mitogen-activated protein kinase pathway. 2002 J. Immunol. pmid:11801678