15-deoxy-delta-12,14-PGJ2

15-deoxy-delta-12,14-pgj2 is a lipid of Fatty Acyls (FA) class. 15-deoxy-delta-12,14-pgj2 is associated with abnormalities such as Dehydration and Myocardial Ischemia. The involved functions are known as Binding (Molecular Function), Inflammation, Alveolar ventilation function, Stimulus and Process. 15-deoxy-delta-12,14-pgj2 often locates in Cytosol, Myocardial tissue and Heart tissue. The associated genes with 15-deoxy-delta-12,14-PGJ2 are Homologous Gene and G-substrate. The related lipids are 15-deoxyprostaglandin J2 and Lipopolysaccharides.

Cross Reference

Introduction

To understand associated biological information of 15-deoxy-delta-12,14-PGJ2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 15-deoxy-delta-12,14-PGJ2?

15-deoxy-delta-12,14-PGJ2 is suspected in Dehydration, Myocardial Ischemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 15-deoxy-delta-12,14-PGJ2

MeSH term MeSH ID Detail
Graves Ophthalmopathy D049970 3 associated lipids
Leukemia, B-Cell D015448 3 associated lipids
Goiter D006042 4 associated lipids
Actinobacillus Infections D000189 4 associated lipids
Lymphoma, T-Cell D016399 11 associated lipids
Myocardial Infarction D009203 21 associated lipids
Fibrosis D005355 23 associated lipids
Lymphoma, B-Cell D016393 24 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Hyperalgesia D006930 42 associated lipids
Thrombosis D013927 49 associated lipids
Parkinson Disease D010300 53 associated lipids
Weight Loss D015431 56 associated lipids
Pain D010146 64 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Colitis D003092 69 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Atherosclerosis D050197 85 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 15-deoxy-delta-12,14-PGJ2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 15-deoxy-delta-12,14-PGJ2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 15-deoxy-delta-12,14-PGJ2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 15-deoxy-delta-12,14-PGJ2?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 15-deoxy-delta-12,14-PGJ2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 15-deoxy-delta-12,14-PGJ2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 15-deoxy-delta-12,14-PGJ2

Download all related citations
Per page 10 20 50 100 | Total 940
Authors Title Published Journal PubMed Link
Li H and Narahara H 15-Deoxy-Δ(12,14)-prostaglandin J(2) induces growth inhibition, cell cycle arrest and apoptosis in human endometrial cancer cell lines. 2013 Int. J. Mol. Med. pmid:23403520
Marcone S and Fitzgerald DJ Proteomic identification of the candidate target proteins of 15-deoxy-delta12,14-prostaglandin J2. 2013 Proteomics pmid:23606334
Sánchez-Gómez FJ et al. Modulation of GSTP1-1 oligomerization by electrophilic inflammatory mediators and reactive drugs. 2013 Inflamm Allergy Drug Targets pmid:23596995
Ramer R et al. COX-2 and PPAR-γ confer cannabidiol-induced apoptosis of human lung cancer cells. 2013 Mol. Cancer Ther. pmid:23220503
Nakamura M et al. Tumor apoptosis in prostate cancer by PGD(2) and its metabolite 15d-PGJ(2) in murine model. 2013 Biomed. Pharmacother. pmid:23206752
Nozaki Y et al. PPARγ ligand attenuates portal inflammation in the MRL-lpr mouse: a new strategy to restrain cholangiopathy in primary biliary cirrhosis. 2013 Med Mol Morphol pmid:23397546
Doyle MC et al. 15-Deoxy-Δ(12,14)-prostaglandin J2 inhibits IL-13 production in T cells via an NF-κB-dependent mechanism. 2013 Biochem. Biophys. Res. Commun. pmid:23333326
Sykes L et al. The CRTH2 agonist Pyl A prevents lipopolysaccharide-induced fetal death but induces preterm labour. 2013 Immunology pmid:23374103
Kuriyan AE et al. Orbital fibroblasts from thyroid eye disease patients differ in proliferative and adipogenic responses depending on disease subtype. 2013 Invest. Ophthalmol. Vis. Sci. pmid:24135759
Ramer R et al. Induction but not inhibition of COX-2 confers human lung cancer cell apoptosis by celecoxib. 2013 J. Lipid Res. pmid:23943857