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Immunol. Cell Biol. |
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15-Deoxy-Delta12,14-prostaglandin J2 enhances docetaxel anti-tumor activity against A549 and H460 non-small-cell lung cancer cell lines and xenograft tumors. |
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Anticancer Drugs |
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Peroxisome proliferator-activated receptor-gamma agonists inhibit respiratory syncytial virus-induced expression of intercellular adhesion molecule-1 in human lung epithelial cells. |
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Immunology |
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J Neuroinflammation |
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Proc. Natl. Acad. Sci. U.S.A. |
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Inhibition of estrogen receptor beta-mediated human telomerase reverse transcriptase gene transcription via the suppression of mitogen-activated protein kinase signaling plays an important role in 15-deoxy-Delta(12,14)-prostaglandin J(2)-induced apoptosis in cancer cells. |
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Exp. Cell Res. |
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15-Deoxy-delta(12,14)-prostaglandin J(2) down-regulates CXCR4 on carcinoma cells through PPARgamma- and NFkappaB-mediated pathways. |
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15-deoxy-Delta(12,14)-prostaglandin J2 inhibits G2-M phase progression in human breast cancer cells via the down-regulation of cyclin B1 and survivin expression. |
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Hypo-responsiveness of interleukin-8 production in human embryonic epithelial intestine 407 cells independent of NF-kappaB pathway: new lessons from endotoxin and ribotoxic deoxynivalenol. |
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Toxicol. Appl. Pharmacol. |
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The hepatotoxic metabolite of acetaminophen directly activates the Keap1-Nrf2 cell defense system. |
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Hepatology |
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Endocrinology |
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15-deoxy-Delta12,14-prostaglandin J2 up-regulates death receptor 5 gene expression in HCT116 cells: involvement of reactive oxygen species and C/EBP homologous transcription factor gene transcription. |
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Mol. Cancer Ther. |
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Mol Pain |
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Molecular characterization of peroxisome proliferator-activated receptors (PPARs) and their gene expression in the differentiating adipocytes of red sea bream Pagrus major. |
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Comp. Biochem. Physiol. B, Biochem. Mol. Biol. |
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The role of 15-deoxy-delta(12,14)-prostaglandin J(2), an endogenous ligand of peroxisome proliferator-activated receptor gamma, in tumor angiogenesis. |
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Biochem. Pharmacol. |
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15-Deoxy-Delta(12,14)-prostaglandin J(2) rescues PC12 cells from H2O2-induced apoptosis through Nrf2-mediated upregulation of heme oxygenase-1: potential roles of Akt and ERK1/2. |
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Biochem. Pharmacol. |
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15-deoxy-Delta(12,14)-prostaglandin J2 induces vascular endothelial cell apoptosis through the sequential activation of MAPKS and p53. |
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Fisetin, morin and myricetin attenuate CD36 expression and oxLDL uptake in U937-derived macrophages. |
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15d-PGJ2 upregulates synthesis of IL-8 in endothelial cells through induction of oxidative stress. |
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Peroxisome proliferator-activated receptor-gamma ligand, 15-deoxy-Delta12,14-prostaglandin J2, reduces neutrophil migration via a nitric oxide pathway. |
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J. Immunol. |
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Opposite roles of STAT and PPARgamma in the induction of p21WAF1 expression by IL-13 in human peripheral blood monocytes. |
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Eur. Cytokine Netw. |
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Stress mediators regulate brain prostaglandin synthesis and peroxisome proliferator-activated receptor-gamma activation after stress in rats. |
2008 |
Endocrinology |
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On the mechanism of inhibition of p27 degradation by 15-deoxy-Delta12,14-prostaglandin J2 in lymphoblasts of Alzheimer's disease patients. |
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Cell. Mol. Life Sci. |
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Effects of 15-deoxy-Delta12, 14 prostaglandin J2 and ciglitazone on human cancer cell cycle progression and death: the role of PPARgamma. |
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Peroxisome proliferator-activated receptor-gamma protects against hepatic ischemia/reperfusion injury in mice. |
2008 |
Hepatology |
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15-Deoxy-Delta12,14-prostaglandin J2 induces chemokine expression, oxidative stress and microfilament reorganization in bovine mammary epithelial cells. |
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J. Dairy Res. |
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The protective effects of 15-deoxy-delta-(12,14)-prostaglandin J2 in spinal cord injury. |
2008 |
Glia |
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PPAR-gamma ligand promotes the growth of APC-mutated HT-29 human colon cancer cells in vitro and in vivo. |
2008 |
Invest New Drugs |
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Hounoki H et al. |
Activation of peroxisome proliferator-activated receptor gamma inhibits TNF-alpha-mediated osteoclast differentiation in human peripheral monocytes in part via suppression of monocyte chemoattractant protein-1 expression. |
2008 |
Bone |
pmid:18242157
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Kim EH et al. |
15-Deoxy-Delta12,14-prostaglandin J2 induces COX-2 expression through Akt-driven AP-1 activation in human breast cancer cells: a potential role of ROS. |
2008 |
Carcinogenesis |
pmid:18192694
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Crabb SJ et al. |
BAG-1 inhibits PPARgamma-induced cell death, but not PPARgamma-induced transcription, cell cycle arrest or differentiation in breast cancer cells. |
2008 |
Oncol. Rep. |
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Hong HY et al. |
Up-regulation of heme oxygenase-1 expression through the Rac1/NADPH oxidase/ROS/p38 signaling cascade mediates the anti-inflammatory effect of 15-deoxy-delta 12,14-prostaglandin J2 in murine macrophages. |
2008 |
FEBS Lett. |
pmid:18291107
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Kimura H et al. |
A natural PPAR-gamma agonist, 15-deoxy-delta 12,14-prostaglandin J2, may act as an enhancer of PAI-1 in human proximal renal tubular cells under hypoxic and inflammatory conditions. |
2008 |
Nephrol. Dial. Transplant. |
pmid:18367541
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