Feng J et al. |
Induction of CD36 expression by oxidized LDL and IL-4 by a common signaling pathway dependent on protein kinase C and PPAR-gamma. |
2000 |
J. Lipid Res. |
pmid:10787429
|
Hardy KD et al. |
Nonenzymatic free radical-catalyzed generation of 15-deoxy-Δ(12,14)-prostaglandin J₂-like compounds (deoxy-J₂-isoprostanes) in vivo. |
2011 |
J. Lipid Res. |
pmid:20944061
|
MartÃnez B et al. |
The mitochondrial respiratory complex I is a target for 15-deoxy-delta12,14-prostaglandin J2 action. |
2005 |
J. Lipid Res. |
pmid:15654126
|
Kim HY et al. |
Upregulation of lipopolysaccharide-induced interleukin-10 by prostaglandin A1 in mouse peritoneal macrophages. |
2008 |
J. Microbiol. Biotechnol. |
pmid:18600064
|
Waku T et al. |
Structural insight into PPARgamma activation through covalent modification with endogenous fatty acids. |
2009 |
J. Mol. Biol. |
pmid:18977231
|
Vishwakarma P et al. |
15d-Prostaglandin J2 induced reactive oxygen species-mediated apoptosis during experimental visceral leishmaniasis. |
2016 |
J. Mol. Med. |
pmid:26830627
|
Abraki SB et al. |
Simultaneous inhibition of COX-2 and activation of PPAR-γ resulted in the same level and pattern of neuroprotection as they were targeted separately. |
2013 |
J. Mol. Neurosci. |
pmid:23132402
|
Heiss EH et al. |
Identification of chromomoric acid C-I as an Nrf2 activator in Chromolaena odorata. |
2014 |
J. Nat. Prod. |
pmid:24476568
|
Haskew-Layton RE et al. |
15-Deoxy-Δ12,14-prostaglandin J2 (15d-PGJ2) protects neurons from oxidative death via an Nrf2 astrocyte-specific mechanism independent of PPARγ. |
2013 |
J. Neurochem. |
pmid:23199167
|
Hosoi T et al. |
Possible involvement of 15-deoxy-Δ(12,14) -prostaglandin J2 in the development of leptin resistance. |
2015 |
J. Neurochem. |
pmid:25662180
|
Liang X et al. |
Prostaglandin D2 mediates neuronal protection via the DP1 receptor. |
2005 |
J. Neurochem. |
pmid:15659218
|
Ajmone-Cat MA et al. |
Prolonged exposure of microglia to lipopolysaccharide modifies the intracellular signaling pathways and selectively promotes prostaglandin E2 synthesis. |
2003 |
J. Neurochem. |
pmid:14622099
|
Phulwani NK et al. |
15-deoxy-Delta12,14-prostaglandin J2 (15d-PGJ2) and ciglitazone modulate Staphylococcus aureus-dependent astrocyte activation primarily through a PPAR-gamma-independent pathway. |
2006 |
J. Neurochem. |
pmid:17074064
|
Bernardo A et al. |
15-deoxy-delta12,14-prostaglandin J2 regulates the functional state and the survival of microglial cells through multiple molecular mechanisms. |
2003 |
J. Neurochem. |
pmid:14535956
|
Kielian T et al. |
S. aureus-dependent microglial activation is selectively attenuated by the cyclopentenone prostaglandin 15-deoxy-Delta12,14- prostaglandin J2 (15d-PGJ2). |
2004 |
J. Neurochem. |
pmid:15312171
|
Saito Y et al. |
Protective effects of 15-deoxy-Delta12,14-prostaglandin J2 against glutamate-induced cell death in primary cortical neuron cultures: induction of adaptive response and enhancement of cell tolerance primarily through up-regulation of cellular glutathione. |
2007 |
J. Neurochem. |
pmid:17697048
|
Storer PD et al. |
Peroxisome proliferator-activated receptor-gamma agonists inhibit the activation of microglia and astrocytes: implications for multiple sclerosis. |
2005 |
J. Neuroimmunol. |
pmid:15748950
|
Zhang F et al. |
Peroxisome proliferator-activated receptor-gamma agonists suppress iNOS expression induced by LPS in rat primary Schwann cells. |
2010 |
J. Neuroimmunol. |
pmid:19942298
|
Drew PD and Chavis JA |
The cyclopentone prostaglandin 15-deoxy-Delta(12,14) prostaglandin J2 represses nitric oxide, TNF-alpha, and IL-12 production by microglial cells. |
2001 |
J. Neuroimmunol. |
pmid:11282151
|
Diab A et al. |
Ligands for the peroxisome proliferator-activated receptor-gamma and the retinoid X receptor exert additive anti-inflammatory effects on experimental autoimmune encephalomyelitis. |
2004 |
J. Neuroimmunol. |
pmid:14975592
|
Garg TK and Chang JY |
Methylmercury causes oxidative stress and cytotoxicity in microglia: attenuation by 15-deoxy-delta 12, 14-prostaglandin J2. |
2006 |
J. Neuroimmunol. |
pmid:16225932
|
Raikwar HP et al. |
PPARgamma antagonists reverse the inhibition of neural antigen-specific Th1 response and experimental allergic encephalomyelitis by Ciglitazone and 15-deoxy-Delta12,14-prostaglandin J2. |
2006 |
J. Neuroimmunol. |
pmid:16844232
|
Zhao ML et al. |
15-deoxy-delta (12,14)-PGJ2 inhibits astrocyte IL-1 signaling: inhibition of NF-kappaB and MAP kinase pathways and suppression of cytokine and chemokine expression. |
2004 |
J. Neuroimmunol. |
pmid:15265671
|
De Nuccio C et al. |
Peroxisome proliferator-activated receptor γ agonists accelerate oligodendrocyte maturation and influence mitochondrial functions and oscillatory Ca(2+) waves. |
2011 |
J. Neuropathol. Exp. Neurol. |
pmid:21937914
|
Bernardo A et al. |
Peroxisome proliferator-activated receptor-gamma agonists promote differentiation and antioxidant defenses of oligodendrocyte progenitor cells. |
2009 |
J. Neuropathol. Exp. Neurol. |
pmid:19535992
|
Heneka MT et al. |
Peroxisome proliferator-activated receptor-gamma ligands reduce neuronal inducible nitric oxide synthase expression and cell death in vivo. |
2000 |
J. Neurosci. |
pmid:10995830
|
Mouihate A et al. |
A novel antipyretic action of 15-deoxy-Delta12,14-prostaglandin J2 in the rat brain. |
2004 |
J. Neurosci. |
pmid:14960602
|
Chattopadhyay N et al. |
Expression of peroxisome proliferator-activated receptors (PPARS) in human astrocytic cells: PPARgamma agonists as inducers of apoptosis. |
2000 |
J. Neurosci. Res. |
pmid:10861801
|
Storer PD et al. |
Cyclopentenone prostaglandins PGA2 and 15-deoxy-delta12,14 PGJ2 suppress activation of murine microglia and astrocytes: implications for multiple sclerosis. |
2005 |
J. Neurosci. Res. |
pmid:15723383
|
Smith SA et al. |
Effects of peroxisome proliferator-activated receptor gamma ligands ciglitazone and 15-deoxy-delta 12,14-prostaglandin J2 on rat cultured cerebellar granule neuronal viability. |
2003 |
J. Neurosci. Res. |
pmid:12774315
|
Kim SE et al. |
15-deoxy-Δ¹²,¹ⴠ-prostaglandin J₂ inhibits human immunodeficiency virus-1 tat-induced monocyte chemoattractant protein-1/CCL2 production by blocking the extracellular signal-regulated kinase-1/2 signaling pathway independently of peroxisome proliferator-activated receptor-γ and heme oxygenase-1 in rat hippocampal slices. |
2012 |
J. Neurosci. Res. |
pmid:22487967
|
Kim NJ et al. |
Concise and enantioselective total synthesis of 15-deoxy-Δ-(12,14)-prostaglandin J(2). |
2010 |
J. Org. Chem. |
pmid:20929274
|
Mirza RE et al. |
Macrophage PPARγ and impaired wound healing in type 2 diabetes. |
2015 |
J. Pathol. |
pmid:25875529
|
Davies GF et al. |
Unique ability of troglitazone to up-regulate peroxisome proliferator-activated receptor-gamma expression in hepatocytes. |
2002 |
J. Pharmacol. Exp. Ther. |
pmid:11752099
|
Yamazaki R et al. |
Nonsteroidal anti-inflammatory drugs induce apoptosis in association with activation of peroxisome proliferator-activated receptor gamma in rheumatoid synovial cells. |
2002 |
J. Pharmacol. Exp. Ther. |
pmid:12065695
|
Almishri W et al. |
Effects of prostaglandin D2, 15-deoxy-Delta12,14-prostaglandin J2, and selective DP1 and DP2 receptor agonists on pulmonary infiltration of eosinophils in Brown Norway rats. |
2005 |
J. Pharmacol. Exp. Ther. |
pmid:15590767
|
Laurora S et al. |
Peroxisome proliferator-activated receptor ligands affect growth-related gene expression in human leukemic cells. |
2003 |
J. Pharmacol. Exp. Ther. |
pmid:12649303
|
Napimoga MH et al. |
15d-prostaglandin J2 inhibits inflammatory hypernociception: involvement of peripheral opioid receptor. |
2008 |
J. Pharmacol. Exp. Ther. |
pmid:17928570
|
Kim EJ et al. |
Peroxisome proliferator-activated receptor-gamma activator 15-deoxy-Delta12,14-prostaglandin J2 inhibits neuroblastoma cell growth through induction of apoptosis: association with extracellular signal-regulated kinase signal pathway. |
2003 |
J. Pharmacol. Exp. Ther. |
pmid:12966153
|
Hata AN et al. |
Expression and molecular pharmacology of the mouse CRTH2 receptor. |
2003 |
J. Pharmacol. Exp. Ther. |
pmid:12721327
|
Shimomura K et al. |
Fenofibrate, troglitazone, and 15-deoxy-Delta12,14-prostaglandin J2 close KATP channels and induce insulin secretion. |
2004 |
J. Pharmacol. Exp. Ther. |
pmid:15201343
|
Raman P et al. |
15-Deoxy-Δ¹²,¹â´-prostaglandin Jâ‚‚-glycerol, a putative metabolite of 2-arachidonyl glycerol and a peroxisome proliferator-activated receptor γ ligand, modulates nuclear factor of activated T cells. |
2012 |
J. Pharmacol. Exp. Ther. |
pmid:22700433
|
Hatanaka M et al. |
15d-prostaglandin J2 enhancement of nerve growth factor-induced neurite outgrowth is blocked by the chemoattractant receptor- homologous molecule expressed on T-helper type 2 cells (CRTH2) antagonist CAY10471 in PC12 cells. |
2010 |
J. Pharmacol. Sci. |
pmid:20424389
|
Azuma Y et al. |
Possible involvement of p38 in mechanisms underlying acceleration of proliferation by 15-deoxy-Delta(12,14)-prostaglandin J2 and the precursors in leukemia cell line THP-1. |
2004 |
J. Pharmacol. Sci. |
pmid:15037811
|
Takata K et al. |
Possible involvement of small oligomers of amyloid-beta peptides in 15-deoxy-delta 12,14 prostaglandin J2-sensitive microglial activation. |
2003 |
J. Pharmacol. Sci. |
pmid:12719662
|
Abdo H et al. |
The omega-6 fatty acid derivative 15-deoxy-Δ¹²,¹â´-prostaglandin J2 is involved in neuroprotection by enteric glial cells against oxidative stress. |
2012 |
J. Physiol. (Lond.) |
pmid:22473776
|
Bach-Ngohou K et al. |
Enteric glia modulate epithelial cell proliferation and differentiation through 15-deoxy-12,14-prostaglandin J2. |
2010 |
J. Physiol. (Lond.) |
pmid:20478974
|
Cha B et al. |
15-deoxy-D12,14-prostaglandin J2 suppresses RANTES expression by inhibiting NADPH oxidase activation in Helicobacter pylori-infected gastric epithelial cells. |
2011 |
J. Physiol. Pharmacol. |
pmid:21673364
|
Korolczuk A et al. |
The role of peroxisome-proliferator-activating receptor gamma agonists: rosiglitazone and 15-deoxy-delta12,14-prostaglandin J2 in chronic experimental cyclosporine A-induced nephrotoxicity. |
2014 |
J. Physiol. Pharmacol. |
pmid:25554991
|
Viergutz T et al. |
Relationship between different stages of the corpus luteum and the expression of the peroxisome proliferator-activated receptor gamma protein in bovine large lutein cells. |
2000 |
J. Reprod. Fertil. |
pmid:10793637
|