Kliewer SA et al. |
Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma. |
1997 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:9113987
|
Straus DS et al. |
15-deoxy-delta 12,14-prostaglandin J2 inhibits multiple steps in the NF-kappa B signaling pathway. |
2000 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:10781090
|
Murata T et al. |
Prostagladin D2 is a mast cell-derived antiangiogenic factor in lung carcinoma. |
2011 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:22106279
|
Kondo M et al. |
15-Deoxy-Delta(12,14)-prostaglandin J(2): the endogenous electrophile that induces neuronal apoptosis. |
2002 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12032289
|
Rajakariar R et al. |
Hematopoietic prostaglandin D2 synthase controls the onset and resolution of acute inflammation through PGD2 and 15-deoxyDelta12 14 PGJ2. |
2007 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:18077391
|
Eggler AL et al. |
Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2. |
2005 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:16006525
|
Oliva JL et al. |
The cyclopentenone 15-deoxy-delta 12,14-prostaglandin J2 binds to and activates H-Ras. |
2003 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12684535
|
Kim KA et al. |
15d-Deoxy-Delta12,14-prostaglandin J2 modulates collagen type I synthesis in human hepatic stellate cells by inducing oxidative stress. |
2005 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:16098720
|
Imaizumi T et al. |
Effect of 15-deoxy-delta12,14-prostaglandin J2 on IL-1beta-induced expression of epithelial neutrophil-activating protein-78 in human endothelial cells. |
2003 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:14580366
|
Berry EB et al. |
Differential effects of serum constituents on apoptosis induced by the cyclopentenone prostaglandin 15-deoxy-delta12,14-prostaglandin J2 in WISH epithelial cells. |
2004 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:15253890
|
Garcia Palacios V et al. |
Expression of adipogenesis markers in a murine stromal cell line treated with 15-deoxy Delta(12,14)-prostaglandin J2, interleukin-11, 9-cis retinoic acid and vitamin K2. |
2001 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:11728175
|
Levine L |
Stimulated release of arachidonic acid by agonists of the peroxisome proliferator-activated receptor and retinoic acid receptors. |
2001 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:11728177
|
Keelan J et al. |
15-deoxy-delta12,14-prostaglandin J2-induced apoptosis in amnion-like WISH cells. |
2001 |
Prostaglandins Other Lipid Mediat. |
pmid:11785780
|
Funovics P et al. |
Effects of 15d-PGJ(2) on VEGF-induced angiogenic activities and expression of VEGF receptors in endothelial cells. |
2006 |
Prostaglandins Other Lipid Mediat. |
pmid:16647637
|
Józkowicz A et al. |
15-deoxy-delta12,14-prostaglandin-J2 inhibits expression of eNOS in human endothelial cells. |
2004 |
Prostaglandins Other Lipid Mediat. |
pmid:15560113
|
Chowdhury AA et al. |
15-Deoxy-Δ(12,14)-prostaglandin J(2) interferes inducible synthesis of prostaglandins E(2) and F(2α) that suppress subsequent adipogenesis program in cultured preadipocytes. |
2011 |
Prostaglandins Other Lipid Mediat. |
pmid:21699992
|
Wang JJ and Mak OT |
Induction of apoptosis by 15d-PGJ2 via ROS formation: an alternative pathway without PPARγ activation in non-small cell lung carcinoma A549 cells. |
2011 |
Prostaglandins Other Lipid Mediat. |
pmid:21396480
|
Maxey KM et al. |
The nature and composition of 15-deoxy-Delta(12,14)PGJ(2). |
2000 |
Prostaglandins Other Lipid Mediat. |
pmid:10936412
|
Clay CE et al. |
15-deoxy-Delta(12,14)PGJ(2) induces diverse biological responses via PPARgamma activation in cancer cells. |
2000 |
Prostaglandins Other Lipid Mediat. |
pmid:10936413
|
Imaizumi T et al. |
15-Deoxy-delta 12,14-prostaglandin J2 inhibits the expression of granulocyte-macrophage colony-stimulating factor in endothelial cells stimulated with lipopolysaccharide. |
2003 |
Prostaglandins Other Lipid Mediat. |
pmid:14518569
|
Ye Y et al. |
Activation of peroxisome proliferator-activated receptor-gamma (PPAR-gamma) by atorvastatin is mediated by 15-deoxy-delta-12,14-PGJ2. |
2007 |
Prostaglandins Other Lipid Mediat. |
pmid:17643887
|
Willermain F et al. |
15-Deoxy-12,14-prostaglandin J2 inhibits interferon gamma induced MHC class II but not class I expression on ARPE cells through a PPAR gamma independent mechanism. |
2006 |
Prostaglandins Other Lipid Mediat. |
pmid:16939878
|
Lim HJ et al. |
PPARgamma activation induces CD36 expression and stimulates foam cell like changes in rVSMCs. |
2006 |
Prostaglandins Other Lipid Mediat. |
pmid:16939881
|
Imaizumi T et al. |
Effect of peroxisome proliferator-activated receptor-gamma ligands on the expression of retinoic acid-inducible gene-I in endothelial cells stimulated with lipopolysaccharide. |
2005 |
Prostaglandins Other Lipid Mediat. |
pmid:16303604
|
Marcone S and Fitzgerald DJ |
Proteomic identification of the candidate target proteins of 15-deoxy-delta12,14-prostaglandin J2. |
2013 |
Proteomics |
pmid:23606334
|
GarcÃa-Bueno B et al. |
The anti-inflammatory prostaglandin 15d-PGJ2 decreases oxidative/nitrosative mediators in brain after acute stress in rats. |
2005 |
Psychopharmacology (Berl.) |
pmid:15719215
|
Wang X et al. |
Potential effects of peroxisome proliferator-activated receptor activator on LPS-induced lung injury in rats. |
2009 |
Pulm Pharmacol Ther |
pmid:19489131
|
Wall SB et al. |
Rac1 modification by an electrophilic 15-deoxy Δ(12,14)-prostaglandin J2 analog. |
2015 |
Redox Biol |
pmid:25677088
|
Higashihara H et al. |
Hypoxia-reoxygenation enhances interleukin-8 production from U937 human monocytic cells. |
2004 |
Redox Rep. |
pmid:15720834
|
Takagi T et al. |
A PPAR-gamma ligand, 15-deoxy-Delta12,14-prostaglandin J(2), inhibited gastric mucosal injury induced by ischemia-reperfusion in rats. |
2004 |
Redox Rep. |
pmid:15720836
|
Bogacka I et al. |
The involvement of peroxisome proliferator activated receptors (PPARs) in prostaglandin F2α production by porcine endometrium. |
2013 |
Reprod Biol |
pmid:24287039
|
Capobianco E et al. |
15-Deoxy-Delta12,14-prostaglandin J2 and peroxisome proliferator-activated receptor gamma (PPARgamma) levels in term placental tissues from control and diabetic rats: modulatory effects of a PPARgamma agonist on nitridergic and lipid placental metabolism. |
2005 |
Reprod. Fertil. Dev. |
pmid:15899154
|
Jawerbaum A et al. |
Peroxynitrites and impaired modulation of nitric oxide concentrations in embryos from diabetic rats during early organogenesis. |
2005 |
Reproduction |
pmid:16264098
|
Jawerbaum A et al. |
Modulation of nitric oxide concentration and lipid metabolism by 15-deoxy Delta12,14prostaglandin J2 in embryos from control and diabetic rats during early organogenesis. |
2002 |
Reproduction |
pmid:12417000
|
Yin Y et al. |
PPARγ agonists regulate tobacco smoke-induced Toll like receptor 4 expression in alveolar macrophages. |
2014 |
Respir. Res. |
pmid:24612634
|
Ji JD et al. |
Inhibition of IL-10-induced STAT3 activation by 15-deoxy-Delta12,14-prostaglandin J2. |
2005 |
Rheumatology (Oxford) |
pmid:15840591
|
Martinez-Cengotitabengoa M et al. |
BDNF and NGF Signalling in Early Phases of Psychosis: Relationship With Inflammation and Response to Antipsychotics After 1 Year. |
2016 |
Schizophr Bull |
pmid:26130821
|
GarcÃa-Bueno B et al. |
Pro-/anti-inflammatory dysregulation in patients with first episode of psychosis: toward an integrative inflammatory hypothesis of schizophrenia. |
2014 |
Schizophr Bull |
pmid:23486748
|
MartÃnez-Gras I et al. |
The anti-inflammatory prostaglandin 15d-PGJ2 and its nuclear receptor PPARgamma are decreased in schizophrenia. |
2011 |
Schizophr. Res. |
pmid:21334179
|
Shibata T et al. |
Identification of a prostaglandin D2 metabolite as a neuritogenesis enhancer targeting the TRPV1 ion channel. |
2016 |
Sci Rep |
pmid:26879669
|
Guan PP et al. |
The role of cyclooxygenase-2, interleukin-1β and fibroblast growth factor-2 in the activation of matrix metalloproteinase-1 in sheared-chondrocytes and articular cartilage. |
2015 |
Sci Rep |
pmid:25992485
|
Garza LA et al. |
Prostaglandin D2 inhibits hair growth and is elevated in bald scalp of men with androgenetic alopecia. |
2012 |
Sci Transl Med |
pmid:22440736
|
Abdelrahman M et al. |
The peroxisome proliferator-activated receptor-gamma ligand 15-deoxyDelta12,14 prostaglandin J2 reduces the organ injury in hemorrhagic shock. |
2004 |
Shock |
pmid:15545828
|
Liu J et al. |
Peroxisome proliferator-activated receptor-gamma ligands 15-deoxy-delta(12,14)-prostaglandin J2 and pioglitazone inhibit hydroxyl peroxide-induced TNF-alpha and lipopolysaccharide-induced CXC chemokine expression in neonatal rat cardiac myocytes. |
2009 |
Shock |
pmid:19174742
|
Monroy MA et al. |
THE PPARgamma ligand 15d-PGJ2 modulates macrophage activation after injury in a murine trauma model. |
2007 |
Shock |
pmid:17510607
|
Zingarelli B et al. |
Diverse cardioprotective signaling mechanisms of peroxisome proliferator-activated receptor-gamma ligands, 15-deoxy-Delta12,14-prostaglandin J2 and ciglitazone, in reperfusion injury: role of nuclear factor-kappaB, heat shock factor 1, and Akt. |
2007 |
Shock |
pmid:17589386
|
Guyton K et al. |
Peroxisome proliferator-activated receptor-gamma agonists modulate macrophage activation by gram-negative and gram-positive bacterial stimuli. |
2003 |
Shock |
pmid:12813370
|
Kaplan J et al. |
Peroxisome proliferator-activated receptor gamma is required for the inhibitory effect of ciglitazone but not 15-deoxy-Delta 12,14-prostaglandin J2 on the NFkappaB pathway in human endothelial cells. |
2007 |
Shock |
pmid:17621259
|
Piraino G et al. |
Synergistic effect of peroxisome proliferator activated receptor-gamma and liver X receptor-alpha in the regulation of inflammation in macrophages. |
2006 |
Shock |
pmid:16878022
|
Hovsepian E et al. |
15-deoxy-Delta12,14 prostaglandin GJ2 but not rosiglitazone regulates metalloproteinase 9, NOS-2, and cyclooxygenase 2 expression and functions by peroxisome proliferator-activated receptor gamma-dependent and -independent mechanisms in cardiac cells. |
2010 |
Shock |
pmid:19997048
|