15-deoxy-delta-12,14-PGJ2

15-deoxy-delta-12,14-pgj2 is a lipid of Fatty Acyls (FA) class. 15-deoxy-delta-12,14-pgj2 is associated with abnormalities such as Dehydration and Myocardial Ischemia. The involved functions are known as Binding (Molecular Function), Inflammation, Alveolar ventilation function, Stimulus and Process. 15-deoxy-delta-12,14-pgj2 often locates in Cytosol, Myocardial tissue and Heart tissue. The associated genes with 15-deoxy-delta-12,14-PGJ2 are Homologous Gene and G-substrate. The related lipids are 15-deoxyprostaglandin J2 and Lipopolysaccharides.

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Introduction

To understand associated biological information of 15-deoxy-delta-12,14-PGJ2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 15-deoxy-delta-12,14-PGJ2?

15-deoxy-delta-12,14-PGJ2 is suspected in Dehydration, Myocardial Ischemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 15-deoxy-delta-12,14-PGJ2

MeSH term MeSH ID Detail
Atherosclerosis D050197 85 associated lipids
Graves Ophthalmopathy D049970 3 associated lipids
Lymphoma, T-Cell D016399 11 associated lipids
Lymphoma, B-Cell D016393 24 associated lipids
Leukemia, B-Cell D015448 3 associated lipids
Weight Loss D015431 56 associated lipids
Thrombosis D013927 49 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Parkinson Disease D010300 53 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Pain D010146 64 associated lipids
Myocardial Infarction D009203 21 associated lipids
Lung Neoplasms D008175 171 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Insulin Resistance D007333 99 associated lipids
Inflammation D007249 119 associated lipids
Hyperalgesia D006930 42 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hemolysis D006461 131 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 15-deoxy-delta-12,14-PGJ2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 15-deoxy-delta-12,14-PGJ2?

Related references are published most in these journals:

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What functions are associated with 15-deoxy-delta-12,14-PGJ2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 15-deoxy-delta-12,14-PGJ2?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 15-deoxy-delta-12,14-PGJ2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 15-deoxy-delta-12,14-PGJ2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 15-deoxy-delta-12,14-PGJ2

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Authors Title Published Journal PubMed Link
Sykes L et al. Chemoattractant receptor homologous to the T helper 2 cell (CRTH2) is not expressed in human amniocytes and myocytes. 2012 PLoS ONE pmid:23226366
Hossain MS et al. Stable expression of lipocalin-type prostaglandin D synthase in cultured preadipocytes impairs adipogenesis program independently of endogenous prostanoids. 2012 Exp. Cell Res. pmid:22100987
Paulitschke V et al. Proteome analysis identified the PPARγ ligand 15d-PGJ2 as a novel drug inhibiting melanoma progression and interfering with tumor-stroma interaction. 2012 PLoS ONE pmid:23049949
Gates D et al. Apo J/clusterin expression and secretion: evidence for 15-deoxy-Δ(12,14)-PGJ(2)-dependent mechanism. 2012 Biochim. Biophys. Acta pmid:22138303
Weng Y et al. Prostaglandin metabolite induces inhibition of TRPA1 and channel-dependent nociception. 2012 Mol Pain pmid:23013719
Bardelli C et al. Autocrine activation of human monocyte/macrophages by monocyte-derived microparticles and modulation by PPARγ ligands. 2012 Br. J. Pharmacol. pmid:21745193
Miyawaki T et al. Combination of midazolam and a cyclooxygenase-2 inhibitor inhibits lipopolysaccharide-induced interleukin-6 production in human peripheral blood mononuclear cells. 2012 Immunopharmacol Immunotoxicol pmid:21854184
Kanakasabai S et al. PPARγ agonists promote oligodendrocyte differentiation of neural stem cells by modulating stemness and differentiation genes. 2012 PLoS ONE pmid:23185633
Pasvanis S et al. High sodium butyrate levels induce MDR1 activation in colorectal cells: Impact of 15-deoxy-Δ(12,14)-prostaglandin J(2) on the resistance to saquinavir. 2012 Biochem. Biophys. Res. Commun. pmid:22293191
Duan Y et al. Peroxisome Proliferator-activated receptor γ activation by ligands and dephosphorylation induces proprotein convertase subtilisin kexin type 9 and low density lipoprotein receptor expression. 2012 J. Biol. Chem. pmid:22593575
Springstead JR et al. Evidence for the importance of OxPAPC interaction with cysteines in regulating endothelial cell function. 2012 J. Lipid Res. pmid:22550136
He S et al. Identification, organ expression and ligand-dependent expression levels of peroxisome proliferator activated receptors in grass carp (Ctenopharyngodon idella). 2012 Comp. Biochem. Physiol. C Toxicol. Pharmacol. pmid:22079418
Clemente-Napimoga JT et al. 15d-PGJ2-loaded in nanocapsules enhance the antinociceptive properties into rat temporomandibular hypernociception. 2012 Life Sci. pmid:22564409
Baek K et al. Myeloid Elf-1-like factor stimulates adipogenic differentiation through the induction of peroxisome proliferator-activated receptor γ expression in bone marrow. 2012 J. Cell. Physiol. pmid:22307523
Martínez AE et al. 15-Deoxy-Δ(12,14)-prostaglandin J2 exerts pro- and anti-inflammatory effects in mesangial cells in a concentration-dependent manner. 2012 Inflamm Allergy Drug Targets pmid:22309084
Farnesi-de-Assunção TS et al. PPAR-γ agonists, mainly 15d-PGJ(2), reduce eosinophil recruitment following allergen challenge. 2012 Cell. Immunol. pmid:22192475
Kuriyan AE et al. Electrophilic PPARγ ligands inhibit corneal fibroblast to myofibroblast differentiation in vitro: a potentially novel therapy for corneal scarring. 2012 Exp. Eye Res. pmid:22178289
Abdo H et al. The omega-6 fatty acid derivative 15-deoxy-Δ¹²,¹⁴-prostaglandin J2 is involved in neuroprotection by enteric glial cells against oxidative stress. 2012 J. Physiol. (Lond.) pmid:22473776
Garza LA et al. Prostaglandin D2 inhibits hair growth and is elevated in bald scalp of men with androgenetic alopecia. 2012 Sci Transl Med pmid:22440736
Cloutier A et al. The prostanoid 15-deoxy-Δ12,14-prostaglandin-j2 reduces lung inflammation and protects mice against lethal influenza infection. 2012 J. Infect. Dis. pmid:22219346
Napimoga MH et al. Exogenous administration of 15d-PGJ2-loaded nanocapsules inhibits bone resorption in a mouse periodontitis model. 2012 J. Immunol. pmid:22706081
Syeda PK et al. Generation of monoclonal antibody for 15-deoxy-Δ¹²,¹⁴-prostaglandin J₂ and development of enzyme-linked immunosorbent assay for its quantification in culture medium of adipocytes. 2012 Appl. Biochem. Biotechnol. pmid:22391692
Quinteiro MS et al. The indirect antinociceptive mechanism of 15d-PGJ2 on rheumatoid arthritis-induced TMJ inflammatory pain in rats. 2012 Eur J Pain pmid:22354681
Prage EB et al. Observation of two modes of inhibition of human microsomal prostaglandin E synthase 1 by the cyclopentenone 15-deoxy-Δ(12,14)-prostaglandin J(2). 2012 Biochemistry pmid:22356188
Numazawa S et al. Possible involvement of transient receptor potential channels in electrophile-induced insulin secretion from RINm5F cells. 2012 Biol. Pharm. Bull. pmid:22382320
Lin YC et al. The glutathionylation of p65 modulates NF-κB activity in 15-deoxy-Δ¹²,¹⁴-prostaglandin J₂-treated endothelial cells. 2012 Free Radic. Biol. Med. pmid:22387200
Kim YI et al. Effects of 15-deoxy-∆¹²,¹⁴-prostaglandin J₂ on the production of IL-8 and the expression of Toll-like receptor 2 in human primary keratinocytes stimulated with lipopolysaccharide. 2011 Mol. Biol. Rep. pmid:20174873
Lotz C et al. Peroxisome-proliferator-activated receptor γ mediates the second window of anaesthetic-induced preconditioning. 2011 Exp. Physiol. pmid:21123361
Tsujita T et al. Nitro-fatty acids and cyclopentenone prostaglandins share strategies to activate the Keap1-Nrf2 system: a study using green fluorescent protein transgenic zebrafish. 2011 Genes Cells pmid:21143560
Neri T et al. Role of NF-kappaB and PPAR-gamma in lung inflammation induced by monocyte-derived microparticles. 2011 Eur. Respir. J. pmid:21148223
Tobiasova Z et al. Peroxisome proliferator-activated receptor-γ agonists prevent in vivo remodeling of human artery induced by alloreactive T cells. 2011 Circulation pmid:21690493
Chowdhury AA et al. 15-Deoxy-Δ(12,14)-prostaglandin J(2) interferes inducible synthesis of prostaglandins E(2) and F(2α) that suppress subsequent adipogenesis program in cultured preadipocytes. 2011 Prostaglandins Other Lipid Mediat. pmid:21699992
Ulivi V et al. Anti-inflammatory activity of monogalactosyldiacylglycerol in human articular cartilage in vitro: activation of an anti-inflammatory cyclooxygenase-2 (COX-2) pathway. 2011 Arthritis Res. Ther. pmid:21682897
Yamamoto Y et al. 15-Deoxy-Δ12,14-prostaglandin J2 enhanced the anti-tumor activity of camptothecin against renal cell carcinoma independently of topoisomerase-II and PPARγ pathways. 2011 Biochem. Biophys. Res. Commun. pmid:21683069
Cha B et al. 15-deoxy-D12,14-prostaglandin J2 suppresses RANTES expression by inhibiting NADPH oxidase activation in Helicobacter pylori-infected gastric epithelial cells. 2011 J. Physiol. Pharmacol. pmid:21673364
Wang P et al. Interleukin-6 synthesis in human chondrocytes is regulated via the antagonistic actions of prostaglandin (PG)E2 and 15-deoxy-Δ(12,14)-PGJ2. 2011 PLoS ONE pmid:22096605
Maekawa N et al. High-performance affinity purification for identification of 15-deoxy-Δ 12,14 -PGJ₂ interacting factors using magnetic nanobeads. 2011 Biomed. Chromatogr. pmid:21374648
Kane CJ et al. Protection of neurons and microglia against ethanol in a mouse model of fetal alcohol spectrum disorders by peroxisome proliferator-activated receptor-γ agonists. 2011 Brain Behav. Immun. pmid:21376806
Martínez-Gras I et al. The anti-inflammatory prostaglandin 15d-PGJ2 and its nuclear receptor PPARgamma are decreased in schizophrenia. 2011 Schizophr. Res. pmid:21334179
Chbicheb S et al. EGR1 expression: a calcium and ERK1/2 mediated PPARγ-independent event involved in the antiproliferative effect of 15-deoxy-Δ12,14-prostaglandin J2 and thiazolidinediones in breast cancer cells. 2011 Biochem. Pharmacol. pmid:21338579
Wang JJ and Mak OT Induction of apoptosis by 15d-PGJ2 via ROS formation: an alternative pathway without PPARγ activation in non-small cell lung carcinoma A549 cells. 2011 Prostaglandins Other Lipid Mediat. pmid:21396480
Murata T et al. Prostagladin D2 is a mast cell-derived antiangiogenic factor in lung carcinoma. 2011 Proc. Natl. Acad. Sci. U.S.A. pmid:22106279
Yamamoto Y et al. Proteomic identification of protein targets for 15-deoxy-Δ(12,14)-prostaglandin J2 in neuronal plasma membrane. 2011 PLoS ONE pmid:21445266
Du H et al. Inhibition of COX-2 expression by endocannabinoid 2-arachidonoylglycerol is mediated via PPAR-γ. 2011 Br. J. Pharmacol. pmid:21501147
Raman P et al. 15-Deoxy-delta12,14-prostaglandin J2-glycerol ester, a putative metabolite of 2-arachidonyl glycerol, activates peroxisome proliferator activated receptor gamma. 2011 Mol. Pharmacol. pmid:21511917
Leamy AW et al. Curcumin ((E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) activates and desensitizes the nociceptor ion channel TRPA1. 2011 Neurosci. Lett. pmid:21855605
Lin TH et al. 15-deoxy-Δ(12,14) -prostaglandin-J2 and ciglitazone inhibit TNF-α-induced matrix metalloproteinase 13 production via the antagonism of NF-κB activation in human synovial fibroblasts. 2011 J. Cell. Physiol. pmid:21344384
Tanaka A et al. Mast cells function as an alternative modulator of adipogenesis through 15-deoxy-delta-12, 14-prostaglandin J2. 2011 Am. J. Physiol., Cell Physiol. pmid:21865589
Surh YJ et al. 15-Deoxy-Δ¹²,¹⁴-prostaglandin J₂, an electrophilic lipid mediator of anti-inflammatory and pro-resolving signaling. 2011 Biochem. Pharmacol. pmid:21843512
Bräutigam K et al. Combined treatment with TRAIL and PPARγ ligands overcomes chemoresistance of ovarian cancer cell lines. 2011 J. Cancer Res. Clin. Oncol. pmid:20878528
Alves C et al. Effects of 15d-PGJâ‚‚-loaded poly(D,L-lactide-co-glycolide) nanocapsules on inflammation. 2011 Br. J. Pharmacol. pmid:20883476
Liu H et al. Modification of ubiquitin-C-terminal hydrolase-L1 by cyclopentenone prostaglandins exacerbates hypoxic injury. 2011 Neurobiol. Dis. pmid:20933087
Tao H and Hajri T Very low density lipoprotein receptor promotes adipocyte differentiation and mediates the proadipogenic effect of peroxisome proliferator-activated receptor gamma agonists. 2011 Biochem. Pharmacol. pmid:21924248
De Nuccio C et al. Peroxisome proliferator-activated receptor γ agonists accelerate oligodendrocyte maturation and influence mitochondrial functions and oscillatory Ca(2+) waves. 2011 J. Neuropathol. Exp. Neurol. pmid:21937914
Song NY et al. Multidrug resistance-associated protein 1 mediates 15-deoxy-Δ(12,14)-prostaglandin J2-induced expression of glutamate cysteine ligase expression via Nrf2 signaling in human breast cancer cells. 2011 Chem. Res. Toxicol. pmid:21728338
Gandhi UH et al. Selenoprotein-dependent up-regulation of hematopoietic prostaglandin D2 synthase in macrophages is mediated through the activation of peroxisome proliferator-activated receptor (PPAR) gamma. 2011 J. Biol. Chem. pmid:21669866
Charles RL et al. Redox regulation of soluble epoxide hydrolase by 15-deoxy-delta-prostaglandin J2 controls coronary hypoxic vasodilation. 2011 Circ. Res. pmid:21164107
Tang FT et al. Tanshinone IIA attenuates atherosclerosis in ApoE(-/-) mice through down-regulation of scavenger receptor expression. 2011 Eur. J. Pharmacol. pmid:20854809
Shao Z et al. Choroidal involution is a key component of oxygen-induced retinopathy. 2011 Invest. Ophthalmol. Vis. Sci. pmid:21546530
Hardy KD et al. Nonenzymatic free radical-catalyzed generation of 15-deoxy-Δ(12,14)-prostaglandin J₂-like compounds (deoxy-J₂-isoprostanes) in vivo. 2011 J. Lipid Res. pmid:20944061
Li N et al. Molecular mechanisms underlying the inhibition of IFN-γ-induced, STAT1-mediated gene transcription in human macrophages by simvastatin and agonists of PPARs and LXRs. 2011 J. Cell. Biochem. pmid:21268089
Gijsbers L et al. Stable reporter cell lines for peroxisome proliferator-activated receptor γ (PPARγ)-mediated modulation of gene expression. 2011 Anal. Biochem. pmid:21354099
Wang JJ and Mak OT Induction of apoptosis in non-small cell lung carcinoma A549 cells by PGDâ‚‚ metabolite, 15d-PGJâ‚‚. 2011 Cell Biol. Int. pmid:21999315
Seno T et al. 15-Deoxy-Δ¹²,¹⁴ prostaglandin J₂ reduces the formation of atherosclerotic lesions in apolipoprotein E knockout mice. 2011 PLoS ONE pmid:22003398
de Jong E et al. Anticancer effects of 15d-prostaglandin-J2 in wild-type and doxorubicin-resistant ovarian cancer cells: novel actions on SIRT1 and HDAC. 2011 PLoS ONE pmid:21957481
Koharudin LM et al. Cyclopentenone prostaglandin-induced unfolding and aggregation of the Parkinson disease-associated UCH-L1. 2010 Proc. Natl. Acad. Sci. U.S.A. pmid:20231490
Pedersen PJ et al. Prostaglandin phospholipid conjugates with unusual biophysical and cytotoxic properties. 2010 Bioorg. Med. Chem. Lett. pmid:20591667
Reddy RC and Standiford TJ Nrf2 and PPAR{gamma}: PPARtnering against oxidant-induced lung injury. 2010 Am. J. Respir. Crit. Care Med. pmid:20634499
Diers AR et al. Modulation of mammary cancer cell migration by 15-deoxy-delta(12,14)-prostaglandin J(2): implications for anti-metastatic therapy. 2010 Biochem. J. pmid:20536428
Rodrigues WF et al. 15d-PGJ(2) modulates acute immune responses to Trypanosoma cruzi infection. 2010 Mem. Inst. Oswaldo Cruz pmid:20428671
Zhu F et al. Prostaglandin (PG)D(2) and 15-deoxy-Delta(12,14)-PGJ(2), but not PGE(2), mediate shear-induced chondrocyte apoptosis via protein kinase A-dependent regulation of polo-like kinases. 2010 Cell Death Differ. pmid:20150912
Syed MA et al. Expression of TREM-1 is inhibited by PGD2 and PGJ2 in macrophages. 2010 Exp. Cell Res. pmid:20797396
Poncin S et al. Oxidative stress: a required condition for thyroid cell proliferation. 2010 Am. J. Pathol. pmid:20093493
Watanabe K et al. 15-deoxy-delta 12,14-prostaglandin J2 prevents inflammatory response and endothelial cell damage in rats with acute obstructive cholangitis. 2010 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:20056897
Kar R et al. Mitochondrial remodeling following fission inhibition by 15d-PGJ2 involves molecular changes in mitochondrial fusion protein OPA1. 2010 Biochem. Biophys. Res. Commun. pmid:20678484
Zhang HX et al. Alteration of biochemical and pathological properties of TDP-43 protein by a lipid mediator, 15-deoxy-Delta(12,14)-prostaglandin J(2). 2010 Exp. Neurol. pmid:20083106
Byrns MC et al. Aldo-keto reductase 1C3 expression in MCF-7 cells reveals roles in steroid hormone and prostaglandin metabolism that may explain its over-expression in breast cancer. 2010 J. Steroid Biochem. Mol. Biol. pmid:20036328
Moraes LA et al. Non-genomic effects of PPARgamma ligands: inhibition of GPVI-stimulated platelet activation. 2010 J. Thromb. Haemost. pmid:20040043
Hatanaka M et al. 15d-prostaglandin J2 enhancement of nerve growth factor-induced neurite outgrowth is blocked by the chemoattractant receptor- homologous molecule expressed on T-helper type 2 cells (CRTH2) antagonist CAY10471 in PC12 cells. 2010 J. Pharmacol. Sci. pmid:20424389
Zhang F et al. Peroxisome proliferator-activated receptor-gamma agonists suppress iNOS expression induced by LPS in rat primary Schwann cells. 2010 J. Neuroimmunol. pmid:19942298
Zorrilla S et al. Selective binding of the fluorescent dye 1-anilinonaphthalene-8-sulfonic acid to peroxisome proliferator-activated receptor gamma allows ligand identification and characterization. 2010 Anal. Biochem. pmid:20025845
Kim NJ et al. Concise and enantioselective total synthesis of 15-deoxy-Δ-(12,14)-prostaglandin J(2). 2010 J. Org. Chem. pmid:20929274
Li H et al. Serum amyloid A activates peroxisome proliferator-activated receptor γ through extracellularly regulated kinase 1/2 and COX-2 expression in hepatocytes. 2010 Biochemistry pmid:20853849
Bancos S et al. Induction of heme oxygenase-1 in normal and malignant B lymphocytes by 15-deoxy-Delta(12,14)-prostaglandin J(2) requires Nrf2. 2010 Cell. Immunol. pmid:20064636
Xue J et al. Aspirin inhibits MMP-9 mRNA expression and release via the PPARalpha/gamma and COX-2/mPGES-1-mediated pathways in macrophages derived from THP-1 cells. 2010 Biomed. Pharmacother. pmid:19880272
Pacienza N et al. 15-deoxy-Delta(12,14)-PGJ(2) induces cell cycle arrest and apoptosis of haematopoietic progenitors. 2010 Br. J. Haematol. pmid:19764987
Kim SH et al. Toluene diisocyanate (TDI) regulates haem oxygenase-1/ferritin expression: implications for toluene diisocyanate-induced asthma. 2010 Clin. Exp. Immunol. pmid:20345975
Zimmer M et al. The connectivity map links iron regulatory protein-1-mediated inhibition of hypoxia-inducible factor-2a translation to the anti-inflammatory 15-deoxy-delta12,14-prostaglandin J2. 2010 Cancer Res. pmid:20354189
Koyama M et al. Histone deacetylase inhibitors and 15-deoxy-Delta12,14-prostaglandin J2 synergistically induce apoptosis. 2010 Clin. Cancer Res. pmid:20371690
Mo C et al. PPARgamma regulates LIF-induced growth and self-renewal of mouse ES cells through Tyk2-Stat3 pathway. 2010 Cell. Signal. pmid:19922793
Toaldo C et al. PPARgamma ligands inhibit telomerase activity and hTERT expression through modulation of the Myc/Mad/Max network in colon cancer cells. 2010 J. Cell. Mol. Med. pmid:19912441
Diers AR et al. Mitochondrial targeting of the electrophilic lipid 15-deoxy-Delta12,14-prostaglandin J2 increases apoptotic efficacy via redox cell signalling mechanisms. 2010 Biochem. J. pmid:19916962
Morgenweck J et al. Activation of peroxisome proliferator-activated receptor gamma in brain inhibits inflammatory pain, dorsal horn expression of Fos, and local edema. 2010 Neuropharmacology pmid:19891980
Lin TH et al. Upregulation of heme oxygenase-1 inhibits the maturation and mineralization of osteoblasts. 2010 J. Cell. Physiol. pmid:20020468
Hovsepian E et al. 15-deoxy-Delta12,14 prostaglandin GJ2 but not rosiglitazone regulates metalloproteinase 9, NOS-2, and cyclooxygenase 2 expression and functions by peroxisome proliferator-activated receptor gamma-dependent and -independent mechanisms in cardiac cells. 2010 Shock pmid:19997048
Théoleyre S et al. HtrA3 is regulated by 15-deoxy-Delta12,14-prostaglandin J2 independently of PPARgamma in clear cell renal cell carcinomas. 2010 Biochem. Biophys. Res. Commun. pmid:19951697
Shim J et al. The peroxisome proliferator-activated receptor gamma ligands, pioglitazone and 15-deoxy-Delta(12,14)-prostaglandin J(2), have antineoplastic effects against hepatitis B virus-associated hepatocellular carcinoma cells. 2010 Int. J. Oncol. pmid:19956851
Bach-Ngohou K et al. Enteric glia modulate epithelial cell proliferation and differentiation through 15-deoxy-12,14-prostaglandin J2. 2010 J. Physiol. (Lond.) pmid:20478974
Yokoyama Y et al. 15-Deoxy-Delta12,14-prostaglandin J2 inhibits angiotensin II-induced fibronectin expression via hepatocyte growth factor induction in human peritoneal mesothelial cells. 2010 Ther Apher Dial pmid:20438519
Poncin S et al. N-acetylcysteine and 15 deoxy-{delta}12,14-prostaglandin J2 exert a protective effect against autoimmune thyroid destruction in vivo but not against interleukin-1{alpha}/interferon {gamma}-induced inhibitory effects in thyrocytes in vitro. 2010 Am. J. Pathol. pmid:20489149