Kim YI et al. |
Effects of 15-deoxy-∆¹²,¹â´-prostaglandin Jâ‚‚ on the production of IL-8 and the expression of Toll-like receptor 2 in human primary keratinocytes stimulated with lipopolysaccharide. |
2011 |
Mol. Biol. Rep. |
pmid:20174873
|
Tsujita T et al. |
Nitro-fatty acids and cyclopentenone prostaglandins share strategies to activate the Keap1-Nrf2 system: a study using green fluorescent protein transgenic zebrafish. |
2011 |
Genes Cells |
pmid:21143560
|
Neri T et al. |
Role of NF-kappaB and PPAR-gamma in lung inflammation induced by monocyte-derived microparticles. |
2011 |
Eur. Respir. J. |
pmid:21148223
|
Tobiasova Z et al. |
Peroxisome proliferator-activated receptor-γ agonists prevent in vivo remodeling of human artery induced by alloreactive T cells. |
2011 |
Circulation |
pmid:21690493
|
Yamamoto Y et al. |
15-Deoxy-Δ12,14-prostaglandin J2 enhanced the anti-tumor activity of camptothecin against renal cell carcinoma independently of topoisomerase-II and PPARγ pathways. |
2011 |
Biochem. Biophys. Res. Commun. |
pmid:21683069
|
Wang P et al. |
Interleukin-6 synthesis in human chondrocytes is regulated via the antagonistic actions of prostaglandin (PG)E2 and 15-deoxy-Δ(12,14)-PGJ2. |
2011 |
PLoS ONE |
pmid:22096605
|
Maekawa N et al. |
High-performance affinity purification for identification of 15-deoxy-Δ 12,14 -PGJ₂ interacting factors using magnetic nanobeads. |
2011 |
Biomed. Chromatogr. |
pmid:21374648
|
MartÃnez-Gras I et al. |
The anti-inflammatory prostaglandin 15d-PGJ2 and its nuclear receptor PPARgamma are decreased in schizophrenia. |
2011 |
Schizophr. Res. |
pmid:21334179
|
Chbicheb S et al. |
EGR1 expression: a calcium and ERK1/2 mediated PPARγ-independent event involved in the antiproliferative effect of 15-deoxy-Δ12,14-prostaglandin J2 and thiazolidinediones in breast cancer cells. |
2011 |
Biochem. Pharmacol. |
pmid:21338579
|
Murata T et al. |
Prostagladin D2 is a mast cell-derived antiangiogenic factor in lung carcinoma. |
2011 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:22106279
|
Lin TH et al. |
15-deoxy-Δ(12,14) -prostaglandin-J2 and ciglitazone inhibit TNF-α-induced matrix metalloproteinase 13 production via the antagonism of NF-κB activation in human synovial fibroblasts. |
2011 |
J. Cell. Physiol. |
pmid:21344384
|
Bräutigam K et al. |
Combined treatment with TRAIL and PPARγ ligands overcomes chemoresistance of ovarian cancer cell lines. |
2011 |
J. Cancer Res. Clin. Oncol. |
pmid:20878528
|
Song NY et al. |
Multidrug resistance-associated protein 1 mediates 15-deoxy-Δ(12,14)-prostaglandin J2-induced expression of glutamate cysteine ligase expression via Nrf2 signaling in human breast cancer cells. |
2011 |
Chem. Res. Toxicol. |
pmid:21728338
|
Hardy KD et al. |
Nonenzymatic free radical-catalyzed generation of 15-deoxy-Δ(12,14)-prostaglandin J₂-like compounds (deoxy-J₂-isoprostanes) in vivo. |
2011 |
J. Lipid Res. |
pmid:20944061
|
Seno T et al. |
15-Deoxy-Δ¹²,¹ⴠprostaglandin J₂ reduces the formation of atherosclerotic lesions in apolipoprotein E knockout mice. |
2011 |
PLoS ONE |
pmid:22003398
|
Koharudin LM et al. |
Cyclopentenone prostaglandin-induced unfolding and aggregation of the Parkinson disease-associated UCH-L1. |
2010 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:20231490
|
Pedersen PJ et al. |
Prostaglandin phospholipid conjugates with unusual biophysical and cytotoxic properties. |
2010 |
Bioorg. Med. Chem. Lett. |
pmid:20591667
|
Reddy RC and Standiford TJ |
Nrf2 and PPAR{gamma}: PPARtnering against oxidant-induced lung injury. |
2010 |
Am. J. Respir. Crit. Care Med. |
pmid:20634499
|
Rodrigues WF et al. |
15d-PGJ(2) modulates acute immune responses to Trypanosoma cruzi infection. |
2010 |
Mem. Inst. Oswaldo Cruz |
pmid:20428671
|
Dionne S et al. |
PPARgamma ligand 15-deoxy-delta 12,14-prostaglandin J2 sensitizes human colon carcinoma cells to TWEAK-induced apoptosis. |
2010 |
Anticancer Res. |
pmid:20150631
|
Zhu F et al. |
Prostaglandin (PG)D(2) and 15-deoxy-Delta(12,14)-PGJ(2), but not PGE(2), mediate shear-induced chondrocyte apoptosis via protein kinase A-dependent regulation of polo-like kinases. |
2010 |
Cell Death Differ. |
pmid:20150912
|
Syed MA et al. |
Expression of TREM-1 is inhibited by PGD2 and PGJ2 in macrophages. |
2010 |
Exp. Cell Res. |
pmid:20797396
|
Schell C et al. |
15-Deoxy-delta 12-14-prostaglandin-J2 induces hypertrophy and loss of contractility in human testicular peritubular cells: implications for human male fertility. |
2010 |
Endocrinology |
pmid:20133451
|
Poncin S et al. |
Oxidative stress: a required condition for thyroid cell proliferation. |
2010 |
Am. J. Pathol. |
pmid:20093493
|
Watanabe K et al. |
15-deoxy-delta 12,14-prostaglandin J2 prevents inflammatory response and endothelial cell damage in rats with acute obstructive cholangitis. |
2010 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:20056897
|
Kar R et al. |
Mitochondrial remodeling following fission inhibition by 15d-PGJ2 involves molecular changes in mitochondrial fusion protein OPA1. |
2010 |
Biochem. Biophys. Res. Commun. |
pmid:20678484
|
Zhang HX et al. |
Alteration of biochemical and pathological properties of TDP-43 protein by a lipid mediator, 15-deoxy-Delta(12,14)-prostaglandin J(2). |
2010 |
Exp. Neurol. |
pmid:20083106
|
Katura T et al. |
15-Deoxy-delta 12,14-prostaglandin J2 biphasically regulates the proliferation of mouse hippocampal neural progenitor cells by modulating the redox state. |
2010 |
Mol. Pharmacol. |
pmid:20086036
|
Byrns MC et al. |
Aldo-keto reductase 1C3 expression in MCF-7 cells reveals roles in steroid hormone and prostaglandin metabolism that may explain its over-expression in breast cancer. |
2010 |
J. Steroid Biochem. Mol. Biol. |
pmid:20036328
|
Moraes LA et al. |
Non-genomic effects of PPARgamma ligands: inhibition of GPVI-stimulated platelet activation. |
2010 |
J. Thromb. Haemost. |
pmid:20040043
|
Hatanaka M et al. |
15d-prostaglandin J2 enhancement of nerve growth factor-induced neurite outgrowth is blocked by the chemoattractant receptor- homologous molecule expressed on T-helper type 2 cells (CRTH2) antagonist CAY10471 in PC12 cells. |
2010 |
J. Pharmacol. Sci. |
pmid:20424389
|
Zhang F et al. |
Peroxisome proliferator-activated receptor-gamma agonists suppress iNOS expression induced by LPS in rat primary Schwann cells. |
2010 |
J. Neuroimmunol. |
pmid:19942298
|
Zorrilla S et al. |
Selective binding of the fluorescent dye 1-anilinonaphthalene-8-sulfonic acid to peroxisome proliferator-activated receptor gamma allows ligand identification and characterization. |
2010 |
Anal. Biochem. |
pmid:20025845
|
Kim NJ et al. |
Concise and enantioselective total synthesis of 15-deoxy-Δ-(12,14)-prostaglandin J(2). |
2010 |
J. Org. Chem. |
pmid:20929274
|
Li H et al. |
Serum amyloid A activates peroxisome proliferator-activated receptor γ through extracellularly regulated kinase 1/2 and COX-2 expression in hepatocytes. |
2010 |
Biochemistry |
pmid:20853849
|
Bancos S et al. |
Induction of heme oxygenase-1 in normal and malignant B lymphocytes by 15-deoxy-Delta(12,14)-prostaglandin J(2) requires Nrf2. |
2010 |
Cell. Immunol. |
pmid:20064636
|
Xue J et al. |
Aspirin inhibits MMP-9 mRNA expression and release via the PPARalpha/gamma and COX-2/mPGES-1-mediated pathways in macrophages derived from THP-1 cells. |
2010 |
Biomed. Pharmacother. |
pmid:19880272
|
Pacienza N et al. |
15-deoxy-Delta(12,14)-PGJ(2) induces cell cycle arrest and apoptosis of haematopoietic progenitors. |
2010 |
Br. J. Haematol. |
pmid:19764987
|
Koyama M et al. |
Histone deacetylase inhibitors and 15-deoxy-Delta12,14-prostaglandin J2 synergistically induce apoptosis. |
2010 |
Clin. Cancer Res. |
pmid:20371690
|
Kim DH et al. |
15-Deoxy-Delta(12,14)-prostaglandin J(2) stabilizes, but functionally inactivates p53 by binding to the cysteine 277 residue. |
2010 |
Oncogene |
pmid:20208557
|
Cho HY et al. |
Nrf2-regulated PPAR{gamma} expression is critical to protection against acute lung injury in mice. |
2010 |
Am. J. Respir. Crit. Care Med. |
pmid:20224069
|
Mo C et al. |
PPARgamma regulates LIF-induced growth and self-renewal of mouse ES cells through Tyk2-Stat3 pathway. |
2010 |
Cell. Signal. |
pmid:19922793
|
Toaldo C et al. |
PPARgamma ligands inhibit telomerase activity and hTERT expression through modulation of the Myc/Mad/Max network in colon cancer cells. |
2010 |
J. Cell. Mol. Med. |
pmid:19912441
|
Diers AR et al. |
Mitochondrial targeting of the electrophilic lipid 15-deoxy-Delta12,14-prostaglandin J2 increases apoptotic efficacy via redox cell signalling mechanisms. |
2010 |
Biochem. J. |
pmid:19916962
|
Morgenweck J et al. |
Activation of peroxisome proliferator-activated receptor gamma in brain inhibits inflammatory pain, dorsal horn expression of Fos, and local edema. |
2010 |
Neuropharmacology |
pmid:19891980
|
Lin TH et al. |
Upregulation of heme oxygenase-1 inhibits the maturation and mineralization of osteoblasts. |
2010 |
J. Cell. Physiol. |
pmid:20020468
|
Hovsepian E et al. |
15-deoxy-Delta12,14 prostaglandin GJ2 but not rosiglitazone regulates metalloproteinase 9, NOS-2, and cyclooxygenase 2 expression and functions by peroxisome proliferator-activated receptor gamma-dependent and -independent mechanisms in cardiac cells. |
2010 |
Shock |
pmid:19997048
|
Théoleyre S et al. |
HtrA3 is regulated by 15-deoxy-Delta12,14-prostaglandin J2 independently of PPARgamma in clear cell renal cell carcinomas. |
2010 |
Biochem. Biophys. Res. Commun. |
pmid:19951697
|
Shim J et al. |
The peroxisome proliferator-activated receptor gamma ligands, pioglitazone and 15-deoxy-Delta(12,14)-prostaglandin J(2), have antineoplastic effects against hepatitis B virus-associated hepatocellular carcinoma cells. |
2010 |
Int. J. Oncol. |
pmid:19956851
|
Mishra N et al. |
Inhibition of mitochondrial division through covalent modification of Drp1 protein by 15 deoxy-Delta(12,14)-prostaglandin J2. |
2010 |
Biochem. Biophys. Res. Commun. |
pmid:20307494
|