Diosmetin

Diosmetin is a lipid of Polyketides (PK) class. Diosmetin is associated with abnormalities such as Renal tubular disorder, Pancreatitis and Asthma. The involved functions are known as inhibitors, apoptogenic cytochrome c release channel activity, Inflammatory Response, Renal function and Cell Death. Diosmetin often locates in Mitochondrial Membranes. The associated genes with Diosmetin are buthionine and NQO.

Cross Reference

Introduction

To understand associated biological information of Diosmetin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Diosmetin?

Diosmetin is suspected in Renal tubular disorder, Pancreatitis, Asthma and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Diosmetin

MeSH term MeSH ID Detail
Carcinoma, Small Cell D018288 21 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Diosmetin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Diosmetin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Diosmetin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Diosmetin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Diosmetin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Diosmetin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Diosmetin

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Authors Title Published Journal PubMed Link
Adamante G et al. Diosmetin as a novel transient receptor potential vanilloid 1 antagonist with antinociceptive activity in mice. 2019 Life Sci. pmid:30447303
Jiang Y et al. Diosmetin Attenuates Akt Signaling Pathway by Modulating Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells (NF-κB)/Inducible Nitric Oxide Synthase (iNOS) in Streptozotocin (STZ)-Induced Diabetic Nephropathy Mice. 2018 Med. Sci. Monit. pmid:30278036
Oak C et al. Diosmetin suppresses human prostate cancer cell proliferation through the induction of apoptosis and cell cycle arrest. 2018 Int. J. Oncol. pmid:29767250
das Graças C de Souza M et al. Protective Effects of Micronized Purified Flavonoid Fraction (MPFF) on a Novel Experimental Model of Chronic Venous Hypertension. 2018 Eur J Vasc Endovasc Surg pmid:29588131
Poór M et al. Pharmacokinetic interaction of diosmetin and silibinin with other drugs: Inhibition of CYP2C9-mediated biotransformation and displacement from serum albumin. 2018 Biomed. Pharmacother. pmid:29710546
Wang C et al. Cytoprotective effects of diosmetin against hydrogen peroxide-induced L02 cell oxidative damage via activation of the Nrf2-ARE signaling pathway. 2018 Mol Med Rep pmid:29568961
Guan C et al. Identification of rosmarinic acid and sulfated flavonoids as inhibitors of microfouling on the surface of eelgrass Zostera marina. 2017 Biofouling pmid:29032711
Yang K et al. Diosmetin protects against ischemia/reperfusion-induced acute kidney injury in mice. 2017 J. Surg. Res. pmid:28624062
Xu Z et al. Radiosensitizing effect of diosmetin on radioresistant lung cancer cells via Akt signaling pathway. 2017 PLoS ONE pmid:28414793
Chen JJ et al. Effects of diosmetin on nine cytochrome P450 isoforms, UGTs and three drug transporters in vitro. 2017 Toxicol. Appl. Pharmacol. pmid:28867436