MeSH term | MeSH ID | Detail |
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Carcinoma, Small Cell | D018288 | 21 associated lipids |
Diosmetin is a lipid of Polyketides (PK) class. Diosmetin is associated with abnormalities such as Renal tubular disorder, Pancreatitis and Asthma. The involved functions are known as inhibitors, apoptogenic cytochrome c release channel activity, Inflammatory Response, Renal function and Cell Death. Diosmetin often locates in Mitochondrial Membranes. The associated genes with Diosmetin are buthionine and NQO.
To understand associated biological information of Diosmetin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Diosmetin is suspected in Renal tubular disorder, Pancreatitis, Asthma and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Diosmetin
MeSH term | MeSH ID | Detail |
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Carcinoma, Small Cell | D018288 | 21 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Adamante G et al. | Diosmetin as a novel transient receptor potential vanilloid 1 antagonist with antinociceptive activity in mice. | 2019 | Life Sci. | pmid:30447303 |
Jiang Y et al. | Diosmetin Attenuates Akt Signaling Pathway by Modulating Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells (NF-κB)/Inducible Nitric Oxide Synthase (iNOS) in Streptozotocin (STZ)-Induced Diabetic Nephropathy Mice. | 2018 | Med. Sci. Monit. | pmid:30278036 |
Oak C et al. | Diosmetin suppresses human prostate cancer cell proliferation through the induction of apoptosis and cell cycle arrest. | 2018 | Int. J. Oncol. | pmid:29767250 |
das Graças C de Souza M et al. | Protective Effects of Micronized Purified Flavonoid Fraction (MPFF) on a Novel Experimental Model of Chronic Venous Hypertension. | 2018 | Eur J Vasc Endovasc Surg | pmid:29588131 |
Poór M et al. | Pharmacokinetic interaction of diosmetin and silibinin with other drugs: Inhibition of CYP2C9-mediated biotransformation and displacement from serum albumin. | 2018 | Biomed. Pharmacother. | pmid:29710546 |
Wang C et al. | Cytoprotective effects of diosmetin against hydrogen peroxide-induced L02 cell oxidative damage via activation of the Nrf2-ARE signaling pathway. | 2018 | Mol Med Rep | pmid:29568961 |
Guan C et al. | Identification of rosmarinic acid and sulfated flavonoids as inhibitors of microfouling on the surface of eelgrass Zostera marina. | 2017 | Biofouling | pmid:29032711 |
Yang K et al. | Diosmetin protects against ischemia/reperfusion-induced acute kidney injury in mice. | 2017 | J. Surg. Res. | pmid:28624062 |
Xu Z et al. | Radiosensitizing effect of diosmetin on radioresistant lung cancer cells via Akt signaling pathway. | 2017 | PLoS ONE | pmid:28414793 |
Chen JJ et al. | Effects of diosmetin on nine cytochrome P450 isoforms, UGTs and three drug transporters in vitro. | 2017 | Toxicol. Appl. Pharmacol. | pmid:28867436 |