palmitic acid

palmitic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Apoptosis, Synthesis, inhibitors, Oxidation and targeting. Palmitic acid often locates in Extracellular, Muscle, Protoplasm, Body tissue and Blood. The related lipids are Palmitates, Sodium Palmitate and saturated fat.

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Introduction

To understand associated biological information of palmitic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with palmitic acid?

There are no associated biomedical information in the current reference collection.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with palmitic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with palmitic acid?

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What functions are associated with palmitic acid?


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What lipids are associated with palmitic acid?

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What genes are associated with palmitic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with palmitic acid?

There are no associated biomedical information in the current reference collection.

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All references with palmitic acid

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Authors Title Published Journal PubMed Link
Guo H et al. Protective Effects of Glucagon-Like Peptide-1 Analog on Renal Tubular Injury in Mice on High-Fat Diet. 2017 Cell. Physiol. Biochem. pmid:28245463
Huang F et al. Protective Effects and Mechanism of Meretrix meretrix Oligopeptides against Nonalcoholic Fatty Liver Disease. 2017 Mar Drugs pmid:28216552
Cieślak A et al. Stealth nanocarriers based sterosomes using PEG post-insertion process. 2017 Eur J Pharm Biopharm pmid:28216002
Xiao YT et al. P38 MAPK Pharmacological Inhibitor SB203580 Alleviates Total Parenteral Nutrition-Induced Loss of Intestinal Barrier Function but Promotes Hepatocyte Lipoapoptosis. 2017 Cell. Physiol. Biochem. pmid:28214831
Duffy CM et al. Identification of a fatty acid binding protein4-UCP2 axis regulating microglial mediated neuroinflammation. 2017 Mol. Cell. Neurosci. pmid:28214555
Aramsangtienchai P et al. -Palmitoylation of Junctional Adhesion Molecule C Regulates Its Tight Junction Localization and Cell Migration. 2017 J. Biol. Chem. pmid:28196865
Varshney R et al. Cytoprotective effect of kaempferol against palmitic acid-induced pancreatic β-cell death through modulation of autophagy via AMPK/mTOR signaling pathway. 2017 Mol. Cell. Endocrinol. pmid:28237721
Tang S et al. Neutral Ceramidase Secreted Via Exosome Protects Against Palmitate-Induced Apoptosis in INS-1 Cells. 2017 Exp. Clin. Endocrinol. Diabetes pmid:28008587
Kumari A et al. Biodegradation of waste grease by Penicillium chrysogenum for production of fatty acid. 2017 Bioresour. Technol. pmid:27978437
Pascual G et al. Targeting metastasis-initiating cells through the fatty acid receptor CD36. 2017 Nature pmid:27974793
Yamamoto T et al. High-Fat Diet-Induced Lysosomal Dysfunction and Impaired Autophagic Flux Contribute to Lipotoxicity in the Kidney. 2017 J. Am. Soc. Nephrol. pmid:27932476
Yuan H et al. AMP-activated protein kinase-mediated expression of heat shock protein beta 1 enhanced insulin sensitivity in the skeletal muscle. 2017 FEBS Lett. pmid:27928820
Yan P et al. Palmitic acid triggers cell apoptosis in RGC-5 retinal ganglion cells through the Akt/FoxO1 signaling pathway. 2017 Metab Brain Dis pmid:27928692
Guo R et al. New mechanism of lipotoxicity in diabetic cardiomyopathy: Deficiency of Endogenous HS Production and ER stress. 2017 Mech. Ageing Dev. pmid:27871808
Kim SK et al. Palmitate induces RIP1/RIP3-dependent necrosis via MLKL-mediated pore formation in the plasma membrane of RAW 264.7 cells. 2017 Biochem. Biophys. Res. Commun. pmid:27856241
Mikłosz A et al. Challenging of AS160/TBC1D4 Alters Intracellular Lipid milieu in L6 Myotubes Incubated With Palmitate. 2017 J. Cell. Physiol. pmid:27714805
Monastero R et al. Methylation patterns of Vegfb promoter are associated with gene and protein expression levels: the effects of dietary fatty acids. 2017 Eur J Nutr pmid:26707994
Estrada-Alcalde I et al. Metabolic Fate of Branched-Chain Amino Acids During Adipogenesis, in Adipocytes From Obese Mice and C2C12 Myotubes. 2017 J. Cell. Biochem. pmid:27689828
Nakamoto K et al. Dysfunctional GPR40/FFAR1 signaling exacerbates pain behavior in mice. 2017 PLoS ONE pmid:28723961
Hara A et al. Human carbonyl reductase 1 participating in intestinal first-pass drug metabolism is inhibited by fatty acids and acyl-CoAs. 2017 Biochem. Pharmacol. pmid:28450226
de Moraes MM et al. Fatty-monastrol derivatives and its cytotoxic effect against melanoma cell growth. 2017 Bioorg. Chem. pmid:28460356
Zhang WY et al. HDL inhibits saturated fatty acid mediated augmentation of innate immune responses in endothelial cells by a novel pathway. 2017 Atherosclerosis pmid:28340361
Liu Q et al. Genetic enhancement of palmitic acid accumulation in cotton seed oil through RNAi down-regulation of ghKAS2 encoding β-ketoacyl-ACP synthase II (KASII). 2017 Plant Biotechnol. J. pmid:27381745
Tomita K et al. Mixed Lineage Kinase 3 Mediates the Induction of CXCL10 by a STAT1-Dependent Mechanism During Hepatocyte Lipotoxicity. 2017 J. Cell. Biochem. pmid:28262979
Murphy BA et al. siRNA-mediated inhibition of SREBP cleavage-activating protein reduces dyslipidemia in spontaneously dysmetabolic rhesus monkeys. 2017 Metab. Clin. Exp. pmid:28521874
Zeidler JD et al. Short-term starvation is a strategy to unravel the cellular capacity of oxidizing specific exogenous/endogenous substrates in mitochondria. 2017 J. Biol. Chem. pmid:28663370
Oddi S et al. Palmitoylation of cysteine 415 of CB receptor affects ligand-stimulated internalization and selective interaction with membrane cholesterol and caveolin 1. 2017 Biochim. Biophys. Acta pmid:28215712
Ansari IH et al. Characterization of Acyl-CoA synthetase isoforms in pancreatic beta cells: Gene silencing shows participation of ACSL3 and ACSL4 in insulin secretion. 2017 Arch. Biochem. Biophys. pmid:28193492
Mirabi P et al. Does different BMI influence oocyte and embryo quality by inducing fatty acid in follicular fluid? 2017 Taiwan J Obstet Gynecol pmid:28420500
Zhao L et al. Serum stearic acid/palmitic acid ratio as a potential predictor of diabetes remission after Roux-en-Y gastric bypass in obesity. 2017 FASEB J. pmid:28007782
Bayard M et al. Free fatty acids and their esters modulate isothermal crystallization of anhydrous milk fat. 2017 Food Chem pmid:27719901
Feng XT et al. Protective role of Pollen Typhae total flavone against the palmitic acid-induced impairment of glucose-stimulated insulin secretion involving GPR40 signaling in INS-1 cells. 2017 Int. J. Mol. Med. pmid:28731171
Wang L et al. MD2 Blockage Protects Obesity-Induced Vascular Remodeling via Activating AMPK/Nrf2. 2017 Obesity (Silver Spring) pmid:28726347
Huang CN et al. Active subfractions of Abelmoschus esculentus substantially prevent free fatty acid-induced β cell apoptosis via inhibiting dipeptidyl peptidase-4. 2017 PLoS ONE pmid:28715446
Yuan L et al. Palmitic acid dysregulates the Hippo-YAP pathway and inhibits angiogenesis by inducing mitochondrial damage and activating the cytosolic DNA sensor cGAS-STING-IRF3 signaling mechanism. 2017 J. Biol. Chem. pmid:28698384
Nguyen TB et al. DGAT1-Dependent Lipid Droplet Biogenesis Protects Mitochondrial Function during Starvation-Induced Autophagy. 2017 Dev. Cell pmid:28697336
Ivanova EP et al. Bactericidal activity of self-assembled palmitic and stearic fatty acid crystals on highly ordered pyrolytic graphite. 2017 Acta Biomater pmid:28688988
Trabelsi I et al. Esterification of Mixed Carboxylic-fatty Anhydrides Using Amberlyst-15 as Heterogeneous Catalyst. 2017 J Oleo Sci pmid:28674327
Weng SL et al. MDD-Palm: Identification of protein S-palmitoylation sites with substrate motifs based on maximal dependence decomposition. 2017 PLoS ONE pmid:28662047
Zhang H et al. Erythropoietin ameliorates PA-induced insulin resistance through the IRS/AKT/FOXO1 and GSK-3β signaling pathway, and inhibits the inflammatory response in HepG2 cells. 2017 Mol Med Rep pmid:28656239
Petit V et al. Importance of the regiospecific distribution of long-chain saturated fatty acids on gut comfort, fat and calcium absorption in infants. 2017 Prostaglandins Leukot. Essent. Fatty Acids pmid:28651696
Tortosa E et al. Dynamic Palmitoylation Targets MAP6 to the Axon to Promote Microtubule Stabilization during Neuronal Polarization. 2017 Neuron pmid:28521134
Leroy C et al. Fatty acid-binding protein3 expression in BeWo cells, a human placental choriocarcinoma cell line. 2017 Prostaglandins Leukot. Essent. Fatty Acids pmid:28515017
Liu C et al. Phycocyanin-Functionalized Selenium Nanoparticles Reverse Palmitic Acid-Induced Pancreatic β Cell Apoptosis by Enhancing Cellular Uptake and Blocking Reactive Oxygen Species (ROS)-Mediated Mitochondria Dysfunction. 2017 J. Agric. Food Chem. pmid:28510423
Wen SY et al. High density lipoprotein (HDL) reverses palmitic acid induced energy metabolism imbalance by switching CD36 and GLUT4 signaling pathways in cardiomyocyte. 2017 J. Cell. Physiol. pmid:28500736
He K et al. Inhibition of NLRP3 inflammasome by thioredoxin-interacting protein in mouse Kupffer cells as a regulatory mechanism for non-alcoholic fatty liver disease development. 2017 Oncotarget pmid:28499273
Thotakura N et al. Chitosan-palmitic acid based polymeric micelles as promising carrier for circumventing pharmacokinetic and drug delivery concerns of tamoxifen. 2017 Int. J. Biol. Macromol. pmid:28483602
Nicholas DA et al. Palmitic acid is a toll-like receptor 4 ligand that induces human dendritic cell secretion of IL-1β. 2017 PLoS ONE pmid:28463985
Torchon E et al. Fasting rapidly increases fatty acid oxidation in white adipose tissue of young broiler chickens. 2017 Adipocyte pmid:28452587
Shikama Y et al. Potential Role of Free Fatty Acids in the Pathogenesis of Periodontitis and Primary Sjögren's Syndrome. 2017 Int J Mol Sci pmid:28420093