| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Galloway CA et al. | Decreasing mitochondrial fission alleviates hepatic steatosis in a murine model of nonalcoholic fatty liver disease. | 2014 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:25080922 |
| Hung DY et al. | Fatty acid binding protein is a major determinant of hepatic pharmacokinetics of palmitate and its metabolites. | 2003 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:12444013 |
| Bederman I et al. | Altered de novo lipogenesis contributes to low adipose stores in cystic fibrosis mice. | 2012 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:22679004 |
| Min HK et al. | Activation of the GP130-STAT3 axis and its potential implications in nonalcoholic fatty liver disease. | 2015 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:25747354 |
| Ito M et al. | High levels of fatty acids increase contractile function of neonatal rabbit hearts during reperfusion following ischemia. | 2010 | Am. J. Physiol. Heart Circ. Physiol. | pmid:20154256 |
| Lloyd S et al. | Differential modulation of glucose, lactate, and pyruvate oxidation by insulin and dichloroacetate in the rat heart. | 2003 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12793977 |
| Folmes KD et al. | The AMPK gamma1 R70Q mutant regulates multiple metabolic and growth pathways in neonatal cardiac myocytes. | 2007 | Am. J. Physiol. Heart Circ. Physiol. | pmid:17906100 |
| Jaswal JS et al. | Effects of adenosine on myocardial glucose and palmitate metabolism after transient ischemia: role of 5'-AMP-activated protein kinase. | 2006 | Am. J. Physiol. Heart Circ. Physiol. | pmid:16648181 |
| Lloyd SG et al. | Impact of low-flow ischemia on substrate oxidation and glycolysis in the isolated perfused rat heart. | 2004 | Am. J. Physiol. Heart Circ. Physiol. | pmid:15001444 |
| Sparagna GC et al. | Attenuation of fatty acid-induced apoptosis by low-dose alcohol in neonatal rat cardiomyocytes. | 2004 | Am. J. Physiol. Heart Circ. Physiol. | pmid:15217794 |
| Fu M et al. | Akt/eNOS signaling pathway mediates inhibition of endothelial progenitor cells by palmitate-induced ceramide. | 2015 | Am. J. Physiol. Heart Circ. Physiol. | pmid:25380816 |
| Soltys CL et al. | Phosphorylation of cardiac protein kinase B is regulated by palmitate. | 2002 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12181135 |
| Burelle Y et al. | Regular exercise is associated with a protective metabolic phenotype in the rat heart. | 2004 | Am. J. Physiol. Heart Circ. Physiol. | pmid:15105170 |
| Gélinas R et al. | Prolonged QT interval and lipid alterations beyond β-oxidation in very long-chain acyl-CoA dehydrogenase null mouse hearts. | 2011 | Am. J. Physiol. Heart Circ. Physiol. | pmid:21685264 |
| Hafstad AD et al. | Perfused hearts from Type 2 diabetic (db/db) mice show metabolic responsiveness to insulin. | 2006 | Am. J. Physiol. Heart Circ. Physiol. | pmid:16327015 |
| O'Donnell JM et al. | Limited functional and metabolic improvements in hypertrophic and healthy rat heart overexpressing the skeletal muscle isoform of SERCA1 by adenoviral gene transfer in vivo. | 2008 | Am. J. Physiol. Heart Circ. Physiol. | pmid:18952713 |
| Longnus SL et al. | Regulation of myocardial fatty acid oxidation by substrate supply. | 2001 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11557544 |
| Sharma V et al. | Metoprolol improves cardiac function and modulates cardiac metabolism in the streptozotocin-diabetic rat. | 2008 | Am. J. Physiol. Heart Circ. Physiol. | pmid:18203848 |
| Jaswal JS et al. | Inhibition of p38 MAPK and AMPK restores adenosine-induced cardioprotection in hearts stressed by antecedent ischemia by altering glucose utilization. | 2007 | Am. J. Physiol. Heart Circ. Physiol. | pmid:17496214 |
| Sambandam N et al. | Chronic activation of PPARalpha is detrimental to cardiac recovery after ischemia. | 2006 | Am. J. Physiol. Heart Circ. Physiol. | pmid:16155108 |
| Ramasamy R et al. | Protection of ischemic hearts by high glucose is mediated, in part, by GLUT-4. | 2001 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11406496 |
| Sakamoto J et al. | Contribution of malonyl-CoA decarboxylase to the high fatty acid oxidation rates seen in the diabetic heart. | 2000 | Am. J. Physiol. Heart Circ. Physiol. | pmid:10749714 |
| Stanley WC et al. | beta-Hydroxybutyrate inhibits myocardial fatty acid oxidation in vivo independent of changes in malonyl-CoA content. | 2003 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12969881 |
| Lehman JJ et al. | The transcriptional coactivator PGC-1alpha is essential for maximal and efficient cardiac mitochondrial fatty acid oxidation and lipid homeostasis. | 2008 | Am. J. Physiol. Heart Circ. Physiol. | pmid:18487436 |
| Wang P et al. | Impact of altered substrate utilization on cardiac function in isolated hearts from Zucker diabetic fatty rats. | 2005 | Am. J. Physiol. Heart Circ. Physiol. | pmid:15615844 |
| Fang CX et al. | Hypertrophic cardiomyopathy in high-fat diet-induced obesity: role of suppression of forkhead transcription factor and atrophy gene transcription. | 2008 | Am. J. Physiol. Heart Circ. Physiol. | pmid:18641278 |
| Hickson-Bick DL et al. | Palmitate-induced apoptosis in neonatal cardiomyocytes is not dependent on the generation of ROS. | 2002 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11788415 |
| King LM et al. | Free fatty acids, but not ketone bodies, protect diabetic rat hearts during low-flow ischemia. | 2001 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11179061 |
| Crozier SJ et al. | Cellular energy status modulates translational control mechanisms in ischemic-reperfused rat hearts. | 2005 | Am. J. Physiol. Heart Circ. Physiol. | pmid:15894572 |
| Kong JY and Rabkin SW | Palmitate-induced cardiac apoptosis is mediated through CPT-1 but not influenced by glucose and insulin. | 2002 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11788422 |
| Allard MF et al. | AMPK and metabolic adaptation by the heart to pressure overload. | 2007 | Am. J. Physiol. Heart Circ. Physiol. | pmid:16920812 |
| Wang Q et al. | Cardiac phosphatase-deficient 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase increases glycolysis, hypertrophy, and myocyte resistance to hypoxia. | 2008 | Am. J. Physiol. Heart Circ. Physiol. | pmid:18456722 |
| Desrois M et al. | Upregulation of eNOS and unchanged energy metabolism in increased susceptibility of the aging type 2 diabetic GK rat heart to ischemic injury. | 2010 | Am. J. Physiol. Heart Circ. Physiol. | pmid:20729402 |
| Pellieux C et al. | Differential effects of high-fat diet on myocardial lipid metabolism in failing and nonfailing hearts with angiotensin II-mediated cardiac remodeling in mice. | 2012 | Am. J. Physiol. Heart Circ. Physiol. | pmid:22408021 |
| How OJ et al. | Influence of substrate supply on cardiac efficiency, as measured by pressure-volume analysis in ex vivo mouse hearts. | 2005 | Am. J. Physiol. Heart Circ. Physiol. | pmid:15764683 |
| Boehm EA et al. | Increased uncoupling proteins and decreased efficiency in palmitate-perfused hyperthyroid rat heart. | 2001 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11179038 |
| Jindal HK et al. | Posttranslational modification of voltage-dependent potassium channel Kv1.5: COOH-terminal palmitoylation modulates its biological properties. | 2008 | Am. J. Physiol. Heart Circ. Physiol. | pmid:18344374 |
| Gambert S et al. | Extracellular glycerol regulates the cardiac energy balance in a working rat heart model. | 2007 | Am. J. Physiol. Heart Circ. Physiol. | pmid:17040970 |
| Terrand J et al. | Calcium-mediated activation of pyruvate dehydrogenase in severely injured postischemic myocardium. | 2001 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11454576 |
| Saeedi R et al. | AMP-activated protein kinase influences metabolic remodeling in H9c2 cells hypertrophied by arginine vasopressin. | 2009 | Am. J. Physiol. Heart Circ. Physiol. | pmid:19376807 |
| Belke DD et al. | Increased expression of SERCA in the hearts of transgenic mice results in increased oxidation of glucose. | 2007 | Am. J. Physiol. Heart Circ. Physiol. | pmid:17142343 |
| Okere IC et al. | Differential effects of saturated and unsaturated fatty acid diets on cardiomyocyte apoptosis, adipose distribution, and serum leptin. | 2006 | Am. J. Physiol. Heart Circ. Physiol. | pmid:16443671 |
| Hopkins TA et al. | Control of cardiac pyruvate dehydrogenase activity in peroxisome proliferator-activated receptor-alpha transgenic mice. | 2003 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12663261 |
| Jaswal JS et al. | Isoproterenol stimulates 5'-AMP-activated protein kinase and fatty acid oxidation in neonatal hearts. | 2010 | Am. J. Physiol. Heart Circ. Physiol. | pmid:20656883 |
| Gandhi M et al. | Role of glucose metabolism in the recovery of postischemic LV mechanical function: effects of insulin and other metabolic modulators. | 2008 | Am. J. Physiol. Heart Circ. Physiol. | pmid:18408129 |
| Chai YC et al. | Relationship of molecular structure to the mechanism of lysophospholipid-induced smooth muscle cell proliferation. | 2000 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11009470 |
| Wang F et al. | Endothelial heparanase secretion after acute hypoinsulinemia is regulated by glucose and fatty acid. | 2009 | Am. J. Physiol. Heart Circ. Physiol. | pmid:19218500 |
| Ravassa S et al. | Antiapoptotic effects of GLP-1 in murine HL-1 cardiomyocytes. | 2011 | Am. J. Physiol. Heart Circ. Physiol. | pmid:21278133 |
| King DM et al. | Bulk shear viscosities of endogenous and exogenous lung surfactants. | 2002 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:11792632 |
| Nishijima K et al. | Interactions among pulmonary surfactant, vernix caseosa, and intestinal enterocytes: intra-amniotic administration of fluorescently liposomes to pregnant rabbits. | 2012 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:22637154 |
| Augusto L et al. | Interaction of bacterial lipopolysaccharide with mouse surfactant protein C inserted into lipid vesicles. | 2001 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:11557581 |
| Ikegami M et al. | SP-D and GM-CSF regulate surfactant homeostasis via distinct mechanisms. | 2001 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:11504698 |
| Fisher AB and Dodia C | Lysosomal-type PLA2 and turnover of alveolar DPPC. | 2001 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:11238016 |
| Schmidt R et al. | Altered fatty acid composition of lung surfactant phospholipids in interstitial lung disease. | 2002 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:12376361 |
| Ritchie IR et al. | Restoration of skeletal muscle leptin response does not precede the exercise-induced recovery of insulin-stimulated glucose uptake in high-fat-fed rats. | 2011 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:21084675 |
| Tucker MZ and Turcotte LP | Brief food restriction increases FA oxidation and glycogen synthesis under insulin-stimulated conditions. | 2002 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:11893627 |
| Khalilieh A et al. | Physiological responses to food deprivation in the house sparrow, a species not adapted to prolonged fasting. | 2012 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:22785424 |
| Gentile CL et al. | Experimental evidence for therapeutic potential of taurine in the treatment of nonalcoholic fatty liver disease. | 2011 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:21957160 |
| Ji H et al. | Interactions of dietary fat and 2,5-anhydro-D-mannitol on energy metabolism in isolated rat hepatocytes. | 2002 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:11832391 |
| Lessard SJ et al. | Exercise training reverses impaired skeletal muscle metabolism induced by artificial selection for low aerobic capacity. | 2011 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:21048074 |
| Racette SB et al. | Racial differences in lipid metabolism in women with abdominal obesity. | 2000 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:10956252 |
| Tappia PS et al. | Phospholipid profile of developing heart of rats exposed to low-protein diet in pregnancy. | 2005 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:16020521 |
| Ramakrishna R et al. | Flux-balance analysis of mitochondrial energy metabolism: consequences of systemic stoichiometric constraints. | 2001 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:11171647 |
| Abbott MJ et al. | CaMKK is an upstream signal of AMP-activated protein kinase in regulation of substrate metabolism in contracting skeletal muscle. | 2009 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:19812359 |
| Philp A et al. | The PGC-1α-related coactivator promotes mitochondrial and myogenic adaptations in C2C12 myotubes. | 2011 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:21795630 |
| Hoshino D et al. | Clenbuterol, a β2-adrenergic agonist, reciprocally alters PGC-1 alpha and RIP140 and reduces fatty acid and pyruvate oxidation in rat skeletal muscle. | 2012 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:22071161 |
| Thrush AB et al. | A single prior bout of exercise protects against palmitate-induced insulin resistance despite an increase in total ceramide content. | 2011 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:21325642 |
| Holloway GP et al. | FAT/CD36-null mice reveal that mitochondrial FAT/CD36 is required to upregulate mitochondrial fatty acid oxidation in contracting muscle. | 2009 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:19625692 |
| Richards JG et al. | Palmitate movement across red and white muscle membranes of rainbow trout. | 2004 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:12969874 |
| Giroud S et al. | Dietary palmitate and linoleate oxidations, oxidative stress, and DNA damage differ according to season in mouse lemurs exposed to a chronic food deprivation. | 2009 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:19625694 |
| Thrush AB et al. | Palmitate acutely induces insulin resistance in isolated muscle from obese but not lean humans. | 2008 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:18305020 |
| Alkhateeb H and Bonen A | Thujone, a component of medicinal herbs, rescues palmitate-induced insulin resistance in skeletal muscle. | 2010 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:20573988 |
| Junkin KA et al. | Resistin acutely impairs insulin-stimulated glucose transport in rodent muscle in the presence, but not absence, of palmitate. | 2009 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:19193939 |
| Schuh RA et al. | Measuring mitochondrial respiration in intact single muscle fibers. | 2012 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:22160545 |
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| Bizeau ME et al. | Increased pyruvate flux capacities account for diet-induced increases in gluconeogenesis in vitro. | 2001 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:11448844 |
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palmitic acid
palmitic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Apoptosis, Synthesis, inhibitors, Oxidation and targeting. Palmitic acid often locates in Extracellular, Muscle, Protoplasm, Body tissue and Blood. The related lipids are Palmitates, Sodium Palmitate and saturated fat.
Cross Reference
Introduction
To understand associated biological information of palmitic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with palmitic acid?
There are no associated biomedical information in the current reference collection.
No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with palmitic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with palmitic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with palmitic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with palmitic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with palmitic acid?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with palmitic acid?
There are no associated biomedical information in the current reference collection.