palmitic acid

palmitic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Apoptosis, Synthesis, inhibitors, Oxidation and targeting. Palmitic acid often locates in Extracellular, Muscle, Protoplasm, Body tissue and Blood. The related lipids are Palmitates, Sodium Palmitate and saturated fat.

Cross Reference

Introduction

To understand associated biological information of palmitic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with palmitic acid?

There are no associated biomedical information in the current reference collection.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with palmitic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with palmitic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with palmitic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with palmitic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with palmitic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with palmitic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with palmitic acid

Download all related citations
Per page 10 20 50 100 | Total 8090
Authors Title Published Journal PubMed Link
Kakimoto PA et al. H2O2 release from the very long chain acyl-CoA dehydrogenase. 2015 Redox Biol pmid:25728796
Kumar S and Tikoo K Independent role of PP2A and mTORc1 in palmitate induced podocyte death. 2015 Biochimie pmid:25724269
Cheng L et al. Palmitic acid induces central leptin resistance and impairs hepatic glucose and lipid metabolism in male mice. 2015 J. Nutr. Biochem. pmid:25724108
He X et al. Biodegradation of fat, oil and grease (FOG) deposits under various redox conditions relevant to sewer environment. 2015 Appl. Microbiol. Biotechnol. pmid:25715780
Díaz-Ruiz A et al. Proteasome Dysfunction Associated to Oxidative Stress and Proteotoxicity in Adipocytes Compromises Insulin Sensitivity in Human Obesity. 2015 Antioxid. Redox Signal. pmid:25714483
Osório J Diabetes: Hepatic lipogenesis independent of insulin in type 2 diabetes mellitus--a paradox clarified. 2015 Nat Rev Endocrinol pmid:25601567
Ahluwalia V et al. Comparative evaluation of two Trichoderma harzianum strains for major secondary metabolite production and antifungal activity. 2015 Nat. Prod. Res. pmid:25248548
Onorato JM et al. Cell-based assay of MGAT2-driven diacylglycerol synthesis for profiling inhibitors: use of a stable isotope-labeled substrate and high-resolution LC/MS. 2015 J. Lipid Res. pmid:25598079
Ravassa S et al. Association of low GLP-1 with oxidative stress is related to cardiac disease and outcome in patients with type 2 diabetes mellitus: a pilot study. 2015 Free Radic. Biol. Med. pmid:25595459
Lu Y et al. Endoplasmic reticulum stress involved in high-fat diet and palmitic acid-induced vascular damages and fenofibrate intervention. 2015 Biochem. Biophys. Res. Commun. pmid:25592967
Sánchez de Medina V et al. Composition of fatty acids in virgin olive oils from cross breeding segregating populations by gas chromatography separation with flame ionization detection. 2015 J. Sci. Food Agric. pmid:25452231
Sensoy O and Weinstein H A mechanistic role of Helix 8 in GPCRs: Computational modeling of the dopamine D2 receptor interaction with the GIPC1-PDZ-domain. 2015 Biochim. Biophys. Acta pmid:25592838
Coraça-Huber DC et al. Antibiotic-loaded calcium carbonate/calcium sulfate granules as co-adjuvant for bone grafting. 2015 J Mater Sci Mater Med pmid:25578698
Cornall LM et al. Direct activation of the proposed anti-diabetic receptor, GPR119 in cardiomyoblasts decreases markers of muscle metabolic activity. 2015 Mol. Cell. Endocrinol. pmid:25578601
Vatner DF et al. Insulin-independent regulation of hepatic triglyceride synthesis by fatty acids. 2015 Proc. Natl. Acad. Sci. U.S.A. pmid:25564660
Trent CM and Goldberg IJ A new pathway regulating autophagy. 2015 J. Lipid Res. pmid:25552477
Lee CW et al. Structural basis for the ligand-binding specificity of fatty acid-binding proteins (pFABP4 and pFABP5) in gentoo penguin. 2015 Biochem. Biophys. Res. Commun. pmid:26206084
Kostelnik KB et al. High metabolic in vivo stability and bioavailability of a palmitoylated ghrelin receptor ligand assessed by mass spectrometry. 2015 Bioorg. Med. Chem. pmid:25541202
Mironova GD et al. Involvement of palmitate/Ca2+(Sr2+)-induced pore in the cycling of ions across the mitochondrial membrane. 2015 Biochim. Biophys. Acta pmid:25450352
Castellanos-Tapia L et al. Apolipoprotein E isoforms 3/3 and 3/4 differentially interact with circulating stearic, palmitic, and oleic fatty acids and lipid levels in Alaskan Natives. 2015 Nutr Res pmid:25727313
Laner M and Hünenberger PH Effect of methanol on the phase-transition properties of glycerol-monopalmitate lipid bilayers investigated using molecular dynamics simulations: in quest of the biphasic effect. 2015 J. Mol. Graph. Model. pmid:25437096
Laner M et al. Long-timescale motions in glycerol-monopalmitate lipid bilayers investigated using molecular dynamics simulation. 2015 J. Mol. Graph. Model. pmid:25437095
Haralampiev I et al. Recruitment of SH-containing peptides to lipid and biological membranes through the use of a palmitic acid functionalized with a maleimide group. 2015 Angew. Chem. Int. Ed. Engl. pmid:25417776
Leonardi A et al. Cationic solid lipid nanoparticles enhance ocular hypotensive effect of melatonin in rabbit. 2015 Int J Pharm pmid:25448580
Tian G et al. Impaired cAMP generation contributes to defective glucose-stimulated insulin secretion after long-term exposure to palmitate. 2015 Diabetes pmid:25281428
Hashim RB et al. Fatty acid compositions of silver catfish, Pangasius sp. farmed in several rivers of Pahang, Malaysia. 2015 J Oleo Sci pmid:25748380
Wang S et al. Plasma nutrient biomarkers are associated with waist-to-height ratio in youth with type 1 diabetes. 2015 J. Nutr. pmid:25733475
Mohanty B et al. Development and characterization of itraconazole-loaded solid lipid nanoparticles for ocular delivery. 2015 Pharm Dev Technol pmid:24490828
Chen G et al. CYP2J2 overexpression attenuates nonalcoholic fatty liver disease induced by high-fat diet in mice. 2015 Am. J. Physiol. Endocrinol. Metab. pmid:25389366
Wang CQ et al. Four new triterpenes and triterpene glycosides from the leaves of Ilex latifolia and their inhibitory activity on triglyceride accumulation. 2015 Fitoterapia pmid:26347952
Lin WC et al. Inhibitory effects of high stability fucoxanthin on palmitic acid-induced lipid accumulation in human adipose-derived stem cells through modulation of long non-coding RNA. 2015 Food Funct pmid:26057608
Poon K et al. Regulation of the orexigenic neuropeptide, enkephalin, by PPARδ and fatty acids in neurons of the hypothalamus and forebrain. 2015 J. Neurochem. pmid:26332891
Yamamoto Y et al. Palmitoleic acid calcium salt: a lubricant and bactericidal powder from natural lipids. 2015 J Oleo Sci pmid:25757432
Nagai T et al. Abundances of Triacylglycerol Positional Isomers and Enantiomers Comprised of a Dipalmitoylglycerol Backbone and Short- or Medium-chain Fatty Acids in Bovine Milk Fat. 2015 J Oleo Sci pmid:26329769
Covington JD et al. Perilipin 3 Differentially Regulates Skeletal Muscle Lipid Oxidation in Active, Sedentary, and Type 2 Diabetic Males. 2015 J. Clin. Endocrinol. Metab. pmid:26171795
Kien CL et al. Lipidomic evidence that lowering the typical dietary palmitate to oleate ratio in humans decreases the leukocyte production of proinflammatory cytokines and muscle expression of redox-sensitive genes. 2015 J. Nutr. Biochem. pmid:26324406
Liu R et al. [Effects of JAZF1 overexpression on proinflammatory cytokines in hepatocytes induced by palmitic acid]. 2015 Zhonghua Gan Zang Bing Za Zhi pmid:26739470
Gong J et al. Fenugreek lactone attenuates palmitate-induced apoptosis and dysfunction in pancreatic β-cells. 2015 World J. Gastroenterol. pmid:26730156
Yoshinaga K et al. Differential effects of triacylglycerol positional isomers containing n-3 series highly unsaturated fatty acids on lipid metabolism in C57BL/6J mice. 2015 J. Nutr. Biochem. pmid:25448607
Yao J et al. Chlamydia trachomatis Scavenges Host Fatty Acids for Phospholipid Synthesis via an Acyl-Acyl Carrier Protein Synthetase. 2015 J. Biol. Chem. pmid:26195634
Pilar Valdecantos M et al. Essential role of Nrf2 in the protective effect of lipoic acid against lipoapoptosis in hepatocytes. 2015 Free Radic. Biol. Med. pmid:25841776
Martínez-García C et al. Renal Lipotoxicity-Associated Inflammation and Insulin Resistance Affects Actin Cytoskeleton Organization in Podocytes. 2015 PLoS ONE pmid:26545114
Leguina-Ruzzi A et al. Increased RhoA/Rho-Kinase Activity and Markers of Endothelial Dysfunction in Young Adult Subjects with Metabolic Syndrome. 2015 Metab Syndr Relat Disord pmid:26512756
Lucena CF et al. Omega-3 supplementation improves pancreatic islet redox status: in vivo and in vitro studies. 2015 Pancreas pmid:25426612
Liu X et al. Hepatocyte X-box binding protein 1 deficiency increases liver injury in mice fed a high-fat/sugar diet. 2015 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:26472223
Deshmukh AS et al. Secretome Analysis of Lipid-Induced Insulin Resistance in Skeletal Muscle Cells by a Combined Experimental and Bioinformatics Workflow. 2015 J. Proteome Res. pmid:26457550
Martínez L et al. Myristic acid potentiates palmitic acid-induced lipotoxicity and steatohepatitis associated with lipodystrophy by sustaning de novo ceramide synthesis. 2015 Oncotarget pmid:26539645
Zhan XR et al. Life and death of human vascular endothelial cells by stimulation with free fatty acids through death receptors. 2015 Horm. Metab. Res. pmid:25230327
Zeng W et al. Inhibition of HMGB1 release via salvianolic acid B-mediated SIRT1 up-regulation protects rats against non-alcoholic fatty liver disease. 2015 Sci Rep pmid:26525891
Harding SV et al. Desaturation index versus isotopically measured de novo lipogenesis as an indicator of acute systemic lipogenesis. 2015 BMC Res Notes pmid:25879456
Li J et al. Nicotinamide ameliorates palmitate-induced ER stress in hepatocytes via cAMP/PKA/CREB pathway-dependent Sirt1 upregulation. 2015 Biochim. Biophys. Acta pmid:26352206
Silva-Neta IC et al. Expression of genes related to tolerance to low temperature for maize seed germination. 2015 Genet. Mol. Res. pmid:25867416
Akimzhanov AM and Boehning D Rapid and transient palmitoylation of the tyrosine kinase Lck mediates Fas signaling. 2015 Proc. Natl. Acad. Sci. U.S.A. pmid:26351666
Perdomo L et al. Protective role of oleic acid against cardiovascular insulin resistance and in the early and late cellular atherosclerotic process. 2015 Cardiovasc Diabetol pmid:26055507
Park JS et al. Concerted action of p62 and Nrf2 protects cells from palmitic acid-induced lipotoxicity. 2015 Biochem. Biophys. Res. Commun. pmid:26325428
Su X et al. PGC-1α Promoter Methylation in Parkinson's Disease. 2015 PLoS ONE pmid:26317511
Nishio N and Isobe K GADD34-deficient mice develop obesity, nonalcoholic fatty liver disease, hepatic carcinoma and insulin resistance. 2015 Sci Rep pmid:26316333
Yu Y et al. Teasaponin improves leptin sensitivity in the prefrontal cortex of obese mice. 2015 Mol Nutr Food Res pmid:26314570
Gehrmann W et al. Antagonism Between Saturated and Unsaturated Fatty Acids in ROS Mediated Lipotoxicity in Rat Insulin-Producing Cells. 2015 Cell. Physiol. Biochem. pmid:26044490
Duffy CM et al. Role of orexin A signaling in dietary palmitic acid-activated microglial cells. 2015 Neurosci. Lett. pmid:26306651
Lu S et al. Saturated fatty acids induce post-transcriptional regulation of HAMP mRNA via AU-rich element-binding protein, human antigen R (HuR). 2015 J. Biol. Chem. pmid:26304124
Shan W et al. Activation of the SIRT1/p66shc antiapoptosis pathway via carnosic acid-induced inhibition of miR-34a protects rats against nonalcoholic fatty liver disease. 2015 Cell Death Dis pmid:26203862
Moreno-Navarrete JM et al. Lipopolysaccharide binding protein is an adipokine involved in the resilience of the mouse adipocyte to inflammation. 2015 Diabetologia pmid:26201685
Afonso MB et al. Necroptosis is a key pathogenic event in human and experimental murine models of non-alcoholic steatohepatitis. 2015 Clin. Sci. pmid:26201023
Seale LA et al. Diet-induced obesity in the selenocysteine lyase knockout mouse. 2015 Antioxid. Redox Signal. pmid:26192035
Shihabudeen MS et al. Chenodeoxycholic acid, an endogenous FXR ligand alters adipokines and reverses insulin resistance. 2015 Mol. Cell. Endocrinol. pmid:26188168
Muramoto S and Sisco E Strategies for potential age dating of fingerprints through the diffusion of sebum molecules on a nonporous surface analyzed using time-of-flight secondary ion mass spectrometry. 2015 Anal. Chem. pmid:26185934
Kim SK et al. Palmitate induces cisternal ER expansion via the activation of XBP-1/CCTα-mediated phospholipid accumulation in RAW 264.7 cells. 2015 Lipids Health Dis pmid:26174230
Chang E et al. Ezetimibe improves hepatic steatosis in relation to autophagy in obese and diabetic rats. 2015 World J. Gastroenterol. pmid:26167075
Xu B et al. Metabolomic profiles reveal key metabolic changes in heat stress-treated mouse Sertoli cells. 2015 Toxicol In Vitro pmid:26165742
Shao Y et al. Pd/Nb2O5/SiO2 catalyst for the direct hydrodeoxygenation of biomass-related compounds to liquid alkanes under mild conditions. 2015 ChemSusChem pmid:25876904
Pardo V et al. Role of hepatocyte S6K1 in palmitic acid-induced endoplasmic reticulum stress, lipotoxicity, insulin resistance and in oleic acid-induced protection. 2015 Food Chem. Toxicol. pmid:25846498
Litwak SA et al. Lipotoxic Stress Induces Pancreatic β-Cell Apoptosis through Modulation of Bcl-2 Proteins by the Ubiquitin-Proteasome System. 2015 J Diabetes Res pmid:26064977
Xiao F et al. Lipoapoptosis induced by saturated free fatty acids stimulates monocyte migration: a novel role for Pannexin1 in liver cells. 2015 Purinergic Signal. pmid:26054298
Inafuku M et al. Intravenous Mycobacterium Bovis Bacillus Calmette-Guérin Ameliorates Nonalcoholic Fatty Liver Disease in Obese, Diabetic ob/ob Mice. 2015 PLoS ONE pmid:26039731
Nakahashi H et al. Evaluation of the Key Odorants in Volatile Oils from Tubers of Apios americana Medikus. 2015 J Oleo Sci pmid:26521814
Ganji SH et al. Niacin inhibits fat accumulation, oxidative stress, and inflammatory cytokine IL-8 in cultured hepatocytes: Impact on non-alcoholic fatty liver disease. 2015 Metab. Clin. Exp. pmid:26024755
Kumar B et al. Lipotoxicity augments glucotoxicity-induced mitochondrial damage in the development of diabetic retinopathy. 2015 Invest. Ophthalmol. Vis. Sci. pmid:26024084
Biswas B et al. Heavy metal-immobilizing organoclay facilitates polycyclic aromatic hydrocarbon biodegradation in mixed-contaminated soil. 2015 J. Hazard. Mater. pmid:26022853
Xin W et al. Acetyl-CoA carboxylase 2 suppression rescues human proximal tubular cells from palmitic acid induced lipotoxicity via autophagy. 2015 Biochem. Biophys. Res. Commun. pmid:26022126
Ximenes Ados A et al. Lipophorin Drives Lipid Incorporation and Metabolism in Insect Trypanosomatids. 2015 Protist pmid:26017666
Hua W et al. CD36 Mediated Fatty Acid-Induced Podocyte Apoptosis via Oxidative Stress. 2015 PLoS ONE pmid:26000608
Shen X et al. Fetuin A promotes lipotoxicity in β cells through the TLR4 signaling pathway and the role of pioglitazone in anti-lipotoxicity. 2015 Mol. Cell. Endocrinol. pmid:25986658
Wu W et al. Metformin attenuates palmitic acid-induced insulin resistance in L6 cells through the AMP-activated protein kinase/sterol regulatory element-binding protein-1c pathway. 2015 Int. J. Mol. Med. pmid:25891779
Totta P et al. Clathrin Heavy Chain Interacts With Estrogen Receptor α and Modulates 17β-Estradiol Signaling. 2015 Mol. Endocrinol. pmid:25860340
Chong LW et al. Fluvastatin attenuates hepatic steatosis-induced fibrogenesis in rats through inhibiting paracrine effect of hepatocyte on hepatic stellate cells. 2015 BMC Gastroenterol pmid:25886887
Hodson N et al. Palmitoylation and palmitoyl-transferases in Plasmodium parasites. 2015 Biochem. Soc. Trans. pmid:25849924
Youssef OA et al. Potential role for snoRNAs in PKR activation during metabolic stress. 2015 Proc. Natl. Acad. Sci. U.S.A. pmid:25848059
Nagata Y et al. Palmitic acid, verified by lipid profiling using secondary ion mass spectrometry, demonstrates anti-multiple myeloma activity. 2015 Leuk. Res. pmid:25846050
Xu Z and Zhong L New insights into the posttranslational regulation of human cytosolic thioredoxin by S-palmitoylation. 2015 Biochem. Biophys. Res. Commun. pmid:25839660
Haghani K et al. TNF-α knockdown alleviates palmitate-induced insulin resistance in C2C12 skeletal muscle cells. 2015 Biochem. Biophys. Res. Commun. pmid:25839650
Chamberlain LH and Shipston MJ The physiology of protein S-acylation. 2015 Physiol. Rev. pmid:25834228
Park JM et al. Cytoprotective effect of hispidin against palmitate-induced lipotoxicity in C2C12 myotubes. 2015 Molecules pmid:25826786
Tse E et al. Fatty Acids Induce a Pro-Inflammatory Gene Expression Profile in Huh-7 Cells That Attenuates the Anti-HCV Action of Interferon. 2015 J. Interferon Cytokine Res. pmid:25588104
Niso-Santano M et al. Unsaturated fatty acids induce non-canonical autophagy. 2015 EMBO J. pmid:25586377
Chen T et al. Mouse SIRT3 attenuates hypertrophy-related lipid accumulation in the heart through the deacetylation of LCAD. 2015 PLoS ONE pmid:25748450
Min HK et al. Activation of the GP130-STAT3 axis and its potential implications in nonalcoholic fatty liver disease. 2015 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:25747354
Morgan-Bathke M et al. Sex and depot differences in ex vivo adipose tissue fatty acid storage and glycerol-3-phosphate acyltransferase activity. 2015 Am. J. Physiol. Endocrinol. Metab. pmid:25738782
Cheong MW et al. Loss of Egr-1 sensitizes pancreatic β-cells to palmitate-induced ER stress and apoptosis. 2015 J. Mol. Med. pmid:25737480
Chandra R et al. Lipid metabolism in response to individual short chain fatty acids during mixotrophic mode of microalgal cultivation: Influence on biodiesel saturation and protein profile. 2015 Bioresour. Technol. pmid:25736905