palmitic acid

palmitic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Apoptosis, Synthesis, inhibitors, Oxidation and targeting. Palmitic acid often locates in Extracellular, Muscle, Protoplasm, Body tissue and Blood. The related lipids are Palmitates, Sodium Palmitate and saturated fat.

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Introduction

To understand associated biological information of palmitic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with palmitic acid?

There are no associated biomedical information in the current reference collection.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with palmitic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with palmitic acid?

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What functions are associated with palmitic acid?


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What lipids are associated with palmitic acid?

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What genes are associated with palmitic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with palmitic acid?

There are no associated biomedical information in the current reference collection.

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All references with palmitic acid

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Authors Title Published Journal PubMed Link
Wang A et al. Effect of palmitic acid on the characteristics and release profiles of rotigotine-loaded microspheres. 2016 Pharm Dev Technol pmid:25697744
Chen X et al. Comparative Proteomic Study of Fatty Acid-treated Myoblasts Reveals Role of Cox-2 in Palmitate-induced Insulin Resistance. 2016 Sci Rep pmid:26899878
Sparks LM et al. ANT1-mediated fatty acid-induced uncoupling as a target for improving myocellular insulin sensitivity. 2016 Diabetologia pmid:26886198
Siculella L et al. Lipid accumulation stimulates the cap-independent translation of SREBP-1a mRNA by promoting hnRNP A1 binding to its 5'-UTR in a cellular model of hepatic steatosis. 2016 Biochim. Biophys. Acta pmid:26869449
Wang X et al. Trans-11 vaccenic acid improves insulin secretion in models of type 2 diabetes in vivo and in vitro. 2016 Mol Nutr Food Res pmid:27061233
Ke J et al. Liraglutide restores angiogenesis in palmitate-impaired human endothelial cells through PI3K/Akt-Foxo1-GTPCH1 pathway. 2016 Peptides pmid:27777063
Shaheen A and Aljebali AM A hypothetical model to solve the controversy over the involvement of UCP2 in palmitate-induced β-cell dysfunction. 2016 Endocrine pmid:27491555
Wan J et al. Characterisation of Fecal Soap Fatty Acids, Calcium Contents, Bacterial Community and Short-Chain Fatty Acids in Sprague Dawley Rats Fed with Different sn-2 Palmitic Triacylglycerols Diets. 2016 PLoS ONE pmid:27783700
Xiong X et al. SIRT6 protects against palmitate-induced pancreatic β-cell dysfunction and apoptosis. 2016 J. Endocrinol. pmid:27601447
Wu J et al. Palmitic acid aggravates inflammation of pancreatic acinar cells by enhancing unfolded protein response induced CCAAT-enhancer-binding protein β-CCAAT-enhancer-binding protein α activation. 2016 Int. J. Biochem. Cell Biol. pmid:27592456
Kuwagata S et al. MicroRNA148b-3p inhibits mTORC1-dependent apoptosis in diabetes by repressing TNFR2 in proximal tubular cells. 2016 Kidney Int. pmid:27591086
Cunha DA et al. Thrombospondin 1 protects pancreatic β-cells from lipotoxicity via the PERK-NRF2 pathway. 2016 Cell Death Differ. pmid:27588705
Wang J et al. Selective synthesis of human milk fat-style structured triglycerides from microalgal oil in a microfluidic reactor packed with immobilized lipase. 2016 Bioresour. Technol. pmid:27566521
Tomohiro T et al. Kinetic controlled affinity labeling of target enzyme with thioester chemistry. 2016 Bioorg. Med. Chem. pmid:27298000
Wang S et al. Zinc deficiency exacerbates while zinc supplement attenuates cardiac hypertrophy in high-fat diet-induced obese mice through modulating p38 MAPK-dependent signaling. 2016 Toxicol. Lett. pmid:27346292
Tidjani Alou M et al. Anaerococcus rubiinfantis sp. nov., isolated from the gut microbiota of a Senegalese infant with severe acute malnutrition. 2016 Anaerobe pmid:27328611
Hamlin AN et al. LRP1 Protein Deficiency Exacerbates Palmitate-induced Steatosis and Toxicity in Hepatocytes. 2016 J. Biol. Chem. pmid:27317662
Gliszczyńska A et al. Synthesis and Biological Evaluation of Novel Phosphatidylcholine Analogues Containing Monoterpene Acids as Potent Antiproliferative Agents. 2016 PLoS ONE pmid:27310666
Shirasuna K et al. Palmitic acid induces interleukin-1β secretion via NLRP3 inflammasomes and inflammatory responses through ROS production in human placental cells. 2016 J. Reprod. Immunol. pmid:27300134
Dai F et al. Fenofibrate improves high-fat diet-induced and palmitate-induced endoplasmic reticulum stress and inflammation in skeletal muscle. 2016 Life Sci. pmid:27297630
Kim SM et al. Role of Inflammatory Signaling in the Differential Effects of Saturated and Poly-unsaturated Fatty Acids on Peripheral Circadian Clocks. 2016 EBioMedicine pmid:27322464
Sandhya KV et al. Extraction of fleshing oil from waste limed fleshings and biodiesel production. 2016 Waste Manag pmid:26445362
DoÄŸru-Koca A et al. Chemotaxonomic perspectives of the Paracaryum (Cynoglosseae, Boraginaceae) taxa based on fruit fatty acid composition. 2016 Phytochemistry pmid:27600716
Ning H et al. Insulin Protects Hepatic Lipotoxicity by Regulating ER Stress through the PI3K/Akt/p53 Involved Pathway Independently of Autophagy Inhibition. 2016 Nutrients pmid:27104558
Ramalingam P and Ko YT Improved oral delivery of resveratrol from N-trimethyl chitosan-g-palmitic acid surface-modified solid lipid nanoparticles. 2016 Colloids Surf B Biointerfaces pmid:26700233
Bashiri A et al. Cellular cholesterol accumulation modulates high fat high sucrose (HFHS) diet-induced ER stress and hepatic inflammasome activation in the development of non-alcoholic steatohepatitis. 2016 Biochim. Biophys. Acta pmid:27090939
Li W et al. EGFR Inhibition Blocks Palmitic Acid-induced inflammation in cardiomyocytes and Prevents Hyperlipidemia-induced Cardiac Injury in Mice. 2016 Sci Rep pmid:27087279
Zhu R et al. Astragaloside IV facilitates glucose transport in C2C12 myotubes through the IRS1/AKT pathway and suppresses the palmitate-induced activation of the IKK/IκBα pathway. 2016 Int. J. Mol. Med. pmid:27082050
Fuaad AA et al. The Use of Microwave-Assisted Solid-Phase Peptide Synthesis and Click Chemistry for the Synthesis of Vaccine Candidates Against Hookworm Infection. 2016 Methods Mol. Biol. pmid:27076158
Zhao M et al. Inhibition of Receptor Interacting Protein Kinases Attenuates Cardiomyocyte Hypertrophy Induced by Palmitic Acid. 2016 Oxid Med Cell Longev pmid:27057269
Wei X et al. Fatty acid synthesis configures the plasma membrane for inflammation in diabetes. 2016 Nature pmid:27806377
Emiola A et al. Crosstalk between the lipopolysaccharide and phospholipid pathways during outer membrane biogenesis in Escherichia coli. 2016 Proc. Natl. Acad. Sci. U.S.A. pmid:26929331
Sun J et al. Free Fatty Acids Activate Renin-Angiotensin System in 3T3-L1 Adipocytes through Nuclear Factor-kappa B Pathway. 2016 J Diabetes Res pmid:26881238
Wang L et al. Decreased MiR-155 Level in the Peripheral Blood of Non-Alcoholic Fatty Liver Disease Patients may Serve as a Biomarker and may Influence LXR Activity. 2016 Cell. Physiol. Biochem. pmid:27832630
Li C et al. Intrarenal renin-angiotensin system mediates fatty acid-induced ER stress in the kidney. 2016 Am. J. Physiol. Renal Physiol. pmid:26672616
Brajkovic S et al. Islet Brain 1 Protects Insulin Producing Cells against Lipotoxicity. 2016 J Diabetes Res pmid:26665154
Takahashi K et al. High-fat diet increases vulnerability to atrial arrhythmia by conduction disturbance via miR-27b. 2016 J. Mol. Cell. Cardiol. pmid:26654778
Shi X et al. Nr2e1 Deficiency Augments Palmitate-Induced Oxidative Stress in Beta Cells. 2016 Oxid Med Cell Longev pmid:26649147
Chen SC et al. Long-chain polyunsaturated fatty acids amend palmitate-induced inflammation and insulin resistance in mouse C2C12 myotubes. 2016 Food Funct pmid:26436985
Schattenberg JM and Lee MS Extracellular Vesicles as Messengers Between Hepatocytes and Macrophages in Nonalcoholic Steatohepatitis. 2016 Gastroenterology pmid:26924096
Liu L et al. Regulation of peroxisome proliferator-activated receptor gamma on milk fat synthesis in dairy cow mammary epithelial cells. 2016 In Vitro Cell. Dev. Biol. Anim. pmid:27287918
Tran DQ et al. Induction of Gnrh mRNA expression by the ω-3 polyunsaturated fatty acid docosahexaenoic acid and the saturated fatty acid palmitate in a GnRH-synthesizing neuronal cell model, mHypoA-GnRH/GFP. 2016 Mol. Cell. Endocrinol. pmid:26923440
Wang X et al. Effects of triacylglycerol structure and solid fat content on fasting responses of mice. 2016 Eur J Nutr pmid:26141258
Xiao J et al. Bee's honey attenuates non-alcoholic steatohepatitis-induced hepatic injury through the regulation of thioredoxin-interacting protein-NLRP3 inflammasome pathway. 2016 Eur J Nutr pmid:26133299
Abreu P et al. Contractile function recovery in severely injured gastrocnemius muscle of rats treated with either oleic or linoleic acid. 2016 Exp. Physiol. pmid:27579497
Garba L et al. Heterologous Expression of PA8FAD9 and Functional Characterization of a Δ9-Fatty Acid Desaturase from a Cold-Tolerant Pseudomonas sp. A8. 2016 Mol. Biotechnol. pmid:27629791
Li R et al. Development of a high-throughput method for real-time assessment of cellular metabolism in intact long skeletal muscle fibre bundles. 2016 J. Physiol. (Lond.) pmid:27619319
Bier DM Saturated Fats and Cardiovascular Disease: Interpretations Not as Simple as They Once Were. 2016 Crit Rev Food Sci Nutr pmid:25774535
Yonekura S et al. Subcellular Localization and Polymorphism of Bovine FABP4 in Bovine Intramuscular Adipocytes. 2016 Anim. Biotechnol. pmid:26913550
Chen L et al. Preparation of Methylated Products of A-type Procyanidin Trimers in Cinnamon Bark and Their Protective Effects on Pancreatic β-Cell. 2016 J. Food Sci. pmid:27074527