palmitic acid

palmitic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Apoptosis, Synthesis, inhibitors, Oxidation and targeting. Palmitic acid often locates in Extracellular, Muscle, Protoplasm, Body tissue and Blood. The related lipids are Palmitates, Sodium Palmitate and saturated fat.

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Introduction

To understand associated biological information of palmitic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with palmitic acid?

There are no associated biomedical information in the current reference collection.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with palmitic acid

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PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with palmitic acid?

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What functions are associated with palmitic acid?


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What lipids are associated with palmitic acid?

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What genes are associated with palmitic acid?

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What common seen animal models are associated with palmitic acid?

There are no associated biomedical information in the current reference collection.

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Authors Title Published Journal PubMed Link
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Lu Z et al. CD36 is upregulated in mice with periodontitis and metabolic syndrome and involved in macrophage gene upregulation by palmitate. 2017 Oral Dis pmid:27753178
Mikłosz A et al. Challenging of AS160/TBC1D4 Alters Intracellular Lipid milieu in L6 Myotubes Incubated With Palmitate. 2017 J. Cell. Physiol. pmid:27714805
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Nakamoto K et al. Dysfunctional GPR40/FFAR1 signaling exacerbates pain behavior in mice. 2017 PLoS ONE pmid:28723961
Chowdhury AI and Bergsten P GLP-1 analogue recovers impaired insulin secretion from human islets treated with palmitate via down-regulation of SOCS2. 2017 Mol. Cell. Endocrinol. pmid:27566229
Mahmoud AM et al. A novel role for small molecule glycomimetics in the protection against lipid-induced endothelial dysfunction: Involvement of Akt/eNOS and Nrf2/ARE signaling. 2017 Biochim. Biophys. Acta pmid:27554845
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Gillet C et al. Osteonecrosis of the Femoral Head: Lipotoxicity Exacerbation in MSC and Modifications of the Bone Marrow Fluid. 2017 Endocrinology pmid:28359085
Akoumi A et al. Palmitate mediated diacylglycerol accumulation causes endoplasmic reticulum stress, Plin2 degradation, and cell death in H9C2 cardiomyoblasts. 2017 Exp. Cell Res. pmid:28336294
Xiao X et al. Zinc alpha2 glycoprotein alleviates palmitic acid-induced intracellular lipid accumulation in hepatocytes. 2017 Mol. Cell. Endocrinol. pmid:27264075
Bentrad N et al. Identification and evaluation of antibacterial agents present in lipophilic fractions isolated from sub-products of Phoenix dactilyfera. 2017 Nat. Prod. Res. pmid:28403631
Cheng CI et al. Free Fatty Acids Induce Autophagy and LOX-1 Upregulation in Cultured Aortic Vascular Smooth Muscle Cells. 2017 J. Cell. Biochem. pmid:28072480
Chen L et al. Influence of resveratrol on endoplasmic reticulum stress and expression of adipokines in adipose tissues/adipocytes induced by high-calorie diet or palmitic acid. 2017 Endocrine pmid:28070709
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Tomita K et al. Mixed Lineage Kinase 3 Mediates the Induction of CXCL10 by a STAT1-Dependent Mechanism During Hepatocyte Lipotoxicity. 2017 J. Cell. Biochem. pmid:28262979
Sadeghi A et al. Resveratrol Ameliorates Palmitate-Induced Inflammation in Skeletal Muscle Cells by Attenuating Oxidative Stress and JNK/NF-κB Pathway in a SIRT1-Independent Mechanism. 2017 J. Cell. Biochem. pmid:28059488
Murphy BA et al. siRNA-mediated inhibition of SREBP cleavage-activating protein reduces dyslipidemia in spontaneously dysmetabolic rhesus monkeys. 2017 Metab. Clin. Exp. pmid:28521874
Yoshida S et al. Molecular Interaction between Intercellular Lipids in the Stratum Corneum and l-Menthol, as Analyzed by Synchrotron X-Ray Diffraction. 2017 Chem. Pharm. Bull. pmid:28154307
Fratantonio D et al. Cyanidin-3-O-glucoside ameliorates palmitate-induced insulin resistance by modulating IRS-1 phosphorylation and release of endothelial derived vasoactive factors. 2017 Biochim. Biophys. Acta pmid:28011403
Wang Y et al. Docosahexaenoyl serotonin emerges as most potent inhibitor of IL-17 and CCL-20 released by blood mononuclear cells from a series of N-acyl serotonins identified in human intestinal tissue. 2017 Biochim. Biophys. Acta pmid:28526351
Cosenza G et al. A novel polymorphism in the oxytocin receptor encoding gene (OXTR) affects milk fatty acid composition in Italian Mediterranean river buffalo. 2017 J. Dairy Res. pmid:28524009
Qi Z et al. Palmitic Acid Curcumin Ester Facilitates Protection of Neuroblastoma against Oligomeric Aβ40 Insult. 2017 Cell. Physiol. Biochem. pmid:29161719
Zhao L et al. Serum stearic acid/palmitic acid ratio as a potential predictor of diabetes remission after Roux-en-Y gastric bypass in obesity. 2017 FASEB J. pmid:28007782
Nagai T et al. Homochiral Asymmetric Triacylglycerol Isomers in Egg Yolk. 2017 J Oleo Sci pmid:29129900
Du H et al. Extraction and the Fatty Acid Profile of Rosa acicularis Seed Oil. 2017 J Oleo Sci pmid:29129896
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Verma P et al. Characterization of AICAR transformylase/IMP cyclohydrolase (ATIC) from Staphylococcus lugdunensis. 2017 FEBS J. pmid:29063699
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Darwiche R et al. Plant pathogenesis-related proteins of the cacao fungal pathogen differ in their lipid-binding specificities. 2017 J. Biol. Chem. pmid:29042440
Matsuki H et al. Ligand partitioning into lipid bilayer membranes under high pressure: Implication of variation in phase-transition temperatures. 2017 Chem. Phys. Lipids pmid:29042237
Leonardini A et al. GLP-1 Receptor Activation Inhibits Palmitate-Induced Apoptosis via Ceramide in Human Cardiac Progenitor Cells. 2017 J. Clin. Endocrinol. Metab. pmid:28938428
Lu Z et al. Cooperative stimulation of atherogenesis by lipopolysaccharide and palmitic acid-rich high fat diet in low-density lipoprotein receptor-deficient mice. 2017 Atherosclerosis pmid:28934649
Alves MNM et al. Exercise Training Protects Cardiomyocytes from Deleterious Effects of Palmitate. 2017 Int J Sports Med pmid:28922681
Palma M et al. Mammary gland and milk fatty acid composition of two dairy goat breeds under feed-restriction. 2017 J. Dairy Res. pmid:28831968
Shinjo S et al. Disruption of the mitochondria-associated ER membrane (MAM) plays a central role in palmitic acid-induced insulin resistance. 2017 Exp. Cell Res. pmid:28827061
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Feng XT et al. Protective role of Pollen Typhae total flavone against the palmitic acid-induced impairment of glucose-stimulated insulin secretion involving GPR40 signaling in INS-1 cells. 2017 Int. J. Mol. Med. pmid:28731171
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Huang CN et al. Active subfractions of Abelmoschus esculentus substantially prevent free fatty acid-induced β cell apoptosis via inhibiting dipeptidyl peptidase-4. 2017 PLoS ONE pmid:28715446
Yuan L et al. Palmitic acid dysregulates the Hippo-YAP pathway and inhibits angiogenesis by inducing mitochondrial damage and activating the cytosolic DNA sensor cGAS-STING-IRF3 signaling mechanism. 2017 J. Biol. Chem. pmid:28698384
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Chen H et al. Effect of temperature on thermal oxidation of palmitic acid studied by combination of EPR spin trapping technique and SPME-GC-MS/MS. 2017 Food Chem pmid:28551258
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