Genkwanin

Genkwanin is a lipid of Polyketides (PK) class. The involved functions are known as Synthesis, Gene Expression, nodulation, Signal Transduction and conjugation. The associated genes with Genkwanin are Genes, Bacterial.

Cross Reference

Introduction

To understand associated biological information of Genkwanin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Genkwanin?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Genkwanin

MeSH term MeSH ID Detail
Osteosarcoma D012516 50 associated lipids
Acne Vulgaris D000152 35 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with Genkwanin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Genkwanin?

There are no associated biomedical information in the current reference collection.

What functions are associated with Genkwanin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Genkwanin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Genkwanin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Genkwanin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Genkwanin

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Authors Title Published Journal PubMed Link
Tao Y et al. Pharmacokinetic comparisons of six components from raw and vinegar-processed Daphne genkwa aqueous extracts following oral administration in rats by employing UHPLC-MS/MS approaches. 2018 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:29428673
Yuan L et al. Metabolism studies on hydroxygenkwanin and genkwanin in human liver microsomes by UHPLC-Q-TOF-MS. 2018 Xenobiotica pmid:28415902
Li Y et al. Genkwanin nanosuspensions: a novel and potential antitumor drug in breast carcinoma therapy. 2017 Drug Deliv pmid:28961040
Fan J et al. Combining Sprague-Dawley rat uterus cell membrane chromatography with HPLC/MS to screen active components from Leonurus artemisia. 2016 Pharm Biol pmid:25858117
Nasr-Bouzaiene N et al. Immunomodulatory and cellular antioxidant activities of pure compounds from Teucrium ramosissimum Desf. 2016 Tumour Biol. pmid:26692099
Nasr Bouzaiene N et al. Effect of apigenin-7-glucoside, genkwanin and naringenin on tyrosinase activity and melanin synthesis in B16F10 melanoma cells. 2016 Life Sci. pmid:26656314
Wei L et al. Ultra high performance liquid chromatography with electrospray ionization tandem mass spectrometry coupled with hierarchical cluster analysis to evaluate Wikstroemia indica (L.) C. A. Mey. from different geographical regions. 2015 J Sep Sci pmid:25866087
Lee H et al. Biosynthesis of Two Flavones, Apigenin and Genkwanin, in Escherichia coli. 2015 J. Microbiol. Biotechnol. pmid:25975614
Wang X et al. Antitumor and immunomodulatory activity of genkwanin on colorectal cancer in the APC(Min/+) mice. 2015 Int. Immunopharmacol. pmid:26388189
Jiang CP et al. Intestinal absorptive transport of Genkwanin from Flos genkwa using a single-pass intestinal perfusion rat model. 2014 Am. J. Chin. Med. pmid:24707867
Gao Y et al. Genkwanin inhibits proinflammatory mediators mainly through the regulation of miR-101/MKP-1/MAPK pathway in LPS-activated macrophages. 2014 PLoS ONE pmid:24800851
Song Y et al. Determination of genkwanin in rat plasma by liquid chromatography-tandem mass spectrometry: application to a bioavailability study. 2013 J Pharm Biomed Anal pmid:23831487
Zimmerman C et al. The small molecule genkwanine M induces single mode, mesenchymal tumor cell motility. 2013 Exp. Cell Res. pmid:23333560
Berim A and Gang DR The roles of a flavone-6-hydroxylase and 7-O-demethylation in the flavone biosynthetic network of sweet basil. 2013 J. Biol. Chem. pmid:23184958
Escandón-Rivera S et al. α-glucosidase inhibitors from Brickellia cavanillesii. 2012 J. Nat. Prod. pmid:22587572
Favela-Hernández JM et al. Antibacterial and antimycobacterial lignans and flavonoids from Larrea tridentata. 2012 Phytother Res pmid:22422605
Gohari AR et al. Evaluation of the cytotoxicity of Satureja spicigera and its main compounds. 2012 ScientificWorldJournal pmid:22623883
Piao GC et al. Cytotoxic fraction from Artemisia sacrorum Ledeb. against three human cancer cell lines and separation and identification of its compounds. 2012 Nat. Prod. Res. pmid:22008023
Danko B et al. In vitro cytotoxic activity of novel protoflavone analogs - selectivity towards a multidrug resistant cancer cell line. 2012 Anticancer Res. pmid:22753749
Ito T et al. Quantification of polyphenols and pharmacological analysis of water and ethanol-based extracts of cultivated agarwood leaves. 2012 J. Nutr. Sci. Vitaminol. pmid:22790572