Genkwanin

Genkwanin is a lipid of Polyketides (PK) class. The involved functions are known as Synthesis, Gene Expression, nodulation, Signal Transduction and conjugation. The associated genes with Genkwanin are Genes, Bacterial.

Cross Reference

Introduction

To understand associated biological information of Genkwanin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Genkwanin?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Genkwanin

MeSH term MeSH ID Detail
Osteosarcoma D012516 50 associated lipids
Acne Vulgaris D000152 35 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with Genkwanin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Genkwanin?

There are no associated biomedical information in the current reference collection.

What functions are associated with Genkwanin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Genkwanin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Genkwanin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Genkwanin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Genkwanin

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Authors Title Published Journal PubMed Link
pmid:
Jiang CP et al. Intestinal absorptive transport of Genkwanin from Flos genkwa using a single-pass intestinal perfusion rat model. 2014 Am. J. Chin. Med. pmid:24707867
Danko B et al. In vitro cytotoxic activity of novel protoflavone analogs - selectivity towards a multidrug resistant cancer cell line. 2012 Anticancer Res. pmid:22753749
Leonard E et al. Expression of a soluble flavone synthase allows the biosynthesis of phytoestrogen derivatives in Escherichia coli. 2006 Appl. Microbiol. Biotechnol. pmid:16025328
Pérez-Fons L et al. Rosemary (Rosmarinus officinalis) diterpenes affect lipid polymorphism and fluidity in phospholipid membranes. 2006 Arch. Biochem. Biophys. pmid:16949545
Saito T et al. Sakuranetin induces adipogenesis of 3T3-L1 cells through enhanced expression of PPARgamma2. 2008 Biochem. Biophys. Res. Commun. pmid:18522800
Fesen MR et al. Inhibition of HIV-1 integrase by flavones, caffeic acid phenethyl ester (CAPE) and related compounds. 1994 Biochem. Pharmacol. pmid:7520698
Androutsopoulos VP et al. Comparative CYP1A1 and CYP1B1 substrate and inhibitor profile of dietary flavonoids. 2011 Bioorg. Med. Chem. pmid:21482471
Hara H et al. Laxative effect of agarwood leaves and its mechanism. 2008 Biosci. Biotechnol. Biochem. pmid:18256503
Lai HY et al. Blechnum orientale Linn - a fern with potential as antioxidant, anticancer and antibacterial agent. 2010 BMC Complement Altern Med pmid:20429956
Zahid M et al. Flavonoid glycosides from Salvia moorcroftiana wall. 2002 Carbohydr. Res. pmid:11861014
Devkota HP et al. Flavonoids from the aerial parts of Diplomorpha canescens. 2010 Chem. Pharm. Bull. pmid:20523001
Mohammadi M et al. Two new coumarins from the chloroform extract of Angelica urumiensis from Iran. 2010 Chem. Pharm. Bull. pmid:20410639
Li Y et al. Genkwanin nanosuspensions: a novel and potential antitumor drug in breast carcinoma therapy. 2017 Drug Deliv pmid:28961040
Ben Sghaier M et al. Flavonoids and sesquiterpenes from Tecurium ramosissimum promote antiproliferation of human cancer cells and enhance antioxidant activity: a structure-activity relationship study. 2011 Environ. Toxicol. Pharmacol. pmid:22004952
Zimmerman C et al. The small molecule genkwanine M induces single mode, mesenchymal tumor cell motility. 2013 Exp. Cell Res. pmid:23333560
Hyldgaard M et al. Essential oils in food preservation: mode of action, synergies, and interactions with food matrix components. 2012 Front Microbiol pmid:22291693
Wang X et al. Antitumor and immunomodulatory activity of genkwanin on colorectal cancer in the APC(Min/+) mice. 2015 Int. Immunopharmacol. pmid:26388189
Borrás Linares I et al. Comparison of different extraction procedures for the comprehensive characterization of bioactive phenolic compounds in Rosmarinus officinalis by reversed-phase high-performance liquid chromatography with diode array detection coupled to electrospray time-of-flight mass spectrometry. 2011 J Chromatogr A pmid:21835416
Kunwar RM et al. Traditional herbal medicine in far-west Nepal: a pharmacological appraisal. 2010 J Ethnobiol Ethnomed pmid:21144003
Sadhu SK et al. Prostaglandin inhibitory and antioxidant components of Cistus laurifolius, a Turkish medicinal plant. 2006 J Ethnopharmacol pmid:16814498
Martini ND et al. Biological activity of five antibacterial flavonoids from Combretum erythrophyllum (Combretaceae). 2004 J Ethnopharmacol pmid:15234754
Mizuochi K et al. New iridoid diesters of glucopyranose from Linaria canadensis (L.) Dum. 2011 J Nat Med pmid:20635154
Song Y et al. Determination of genkwanin in rat plasma by liquid chromatography-tandem mass spectrometry: application to a bioavailability study. 2013 J Pharm Biomed Anal pmid:23831487
Wei L et al. Ultra high performance liquid chromatography with electrospray ionization tandem mass spectrometry coupled with hierarchical cluster analysis to evaluate Wikstroemia indica (L.) C. A. Mey. from different geographical regions. 2015 J Sep Sci pmid:25866087
Li YN et al. A simple and efficient protocol for large-scale preparation of three flavonoids from the flower of Daphne genkwa by combination of macroporous resin and counter-current chromatography. 2010 J Sep Sci pmid:20535750
Bai N et al. Flavonoids and phenolic compounds from Rosmarinus officinalis. 2010 J. Agric. Food Chem. pmid:20397728
Jordán MJ et al. Introduction of distillate rosemary leaves into the diet of the Murciano-Granadina goat: transfer of polyphenolic compounds to goats' milk and the plasma of suckling goat kids. 2010 J. Agric. Food Chem. pmid:20608728
Pérez-Fons L et al. Relationship between the antioxidant capacity and effect of rosemary (Rosmarinus officinalis L.) polyphenols on membrane phospholipid order. 2010 J. Agric. Food Chem. pmid:19924866
del Baño MJ et al. Phenolic diterpenes, flavones, and rosmarinic acid distribution during the development of leaves, flowers, stems, and roots of Rosmarinus officinalis. Antioxidant activity. 2003 J. Agric. Food Chem. pmid:12848492
Ibañez E et al. Subcritical water extraction of antioxidant compounds from rosemary plants. 2003 J. Agric. Food Chem. pmid:12517098
del Baño MJ et al. Flavonoid distribution during the development of leaves, flowers, stems, and roots of Rosmarinus officinalis. postulation of a biosynthetic pathway. 2004 J. Agric. Food Chem. pmid:15291464
Berim A and Gang DR The roles of a flavone-6-hydroxylase and 7-O-demethylation in the flavone biosynthetic network of sweet basil. 2013 J. Biol. Chem. pmid:23184958
Tao Y et al. Pharmacokinetic comparisons of six components from raw and vinegar-processed Daphne genkwa aqueous extracts following oral administration in rats by employing UHPLC-MS/MS approaches. 2018 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:29428673
Jeon YM et al. Biological synthesis of 7-O-methyl Apigenin from naringenin using escherichia coli expressing two genes. 2009 J. Microbiol. Biotechnol. pmid:19494697
Lee H et al. Biosynthesis of Two Flavones, Apigenin and Genkwanin, in Escherichia coli. 2015 J. Microbiol. Biotechnol. pmid:25975614
Escandón-Rivera S et al. α-glucosidase inhibitors from Brickellia cavanillesii. 2012 J. Nat. Prod. pmid:22587572
Cao S et al. Cytotoxic triterpenoids from Acridocarpus vivy from the Madagascar rain forest. 2004 J. Nat. Prod. pmid:15217279
Jones WP et al. Cytotoxic constituents from the fruiting branches of Callicarpa americana collected in southern Florida. 2007 J. Nat. Prod. pmid:17279798
Ito T et al. Quantification of polyphenols and pharmacological analysis of water and ethanol-based extracts of cultivated agarwood leaves. 2012 J. Nutr. Sci. Vitaminol. pmid:22790572
Santos-Gomes PC et al. Determination of phenolic antioxidant compounds produced by calli and cell suspensions of sage (Salvia officinalis L.). 2003 J. Plant Physiol. pmid:14593803
Nasr Bouzaiene N et al. Effect of apigenin-7-glucoside, genkwanin and naringenin on tyrosinase activity and melanin synthesis in B16F10 melanoma cells. 2016 Life Sci. pmid:26656314
Brozic P et al. Flavonoids and cinnamic acid derivatives as inhibitors of 17beta-hydroxysteroid dehydrogenase type 1. 2009 Mol. Cell. Endocrinol. pmid:18835421
Maia GL et al. Flavonoids from Praxelis clematidea R.M. King and Robinson modulate bacterial drug resistance. 2011 Molecules pmid:21666549
Piao GC et al. Cytotoxic fraction from Artemisia sacrorum Ledeb. against three human cancer cell lines and separation and identification of its compounds. 2012 Nat. Prod. Res. pmid:22008023
Su J et al. Flavonoids from Daphne giraldii Nitsche. 2008 Nat. Prod. Res. pmid:19023794
Fan J et al. Combining Sprague-Dawley rat uterus cell membrane chromatography with HPLC/MS to screen active components from Leonurus artemisia. 2016 Pharm Biol pmid:25858117
Sati SC et al. Bioactive constituents and medicinal importance of genus Alnus. 2011 Pharmacogn Rev pmid:22279375
Ahmed MS et al. A weakly antimalarial biflavanone from Rhus retinorrhoea. 2001 Phytochemistry pmid:11576606
Henchiri H et al. Sesquiterpenoids from Teucrium ramosissimum. Phytochemistry pmid:19766274