baicalein

baicalein is a lipid of Polyketides (PK) class. Baicalein is associated with abnormalities such as Neurodegenerative Disorders, Fibrillation, Hypertensive disease, Aortic coarctation and Coronary Occlusion. The involved functions are known as Anabolism, Polymerization, Process, inhibitors and Pathogenesis. Baicalein often locates in Membrane, Lipid Bilayers, soluble, Cell-Free System and Protoplasm. The associated genes with baicalein are P4HTM gene, BIRC5 gene, TSPO gene, SHOC2 gene and XIAP gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, iodoresiniferatoxin, Lipopolysaccharides and 17-octadecynoic acid. The related experimental models are Knock-out, Mouse Model and Parkinsonism, Experimental.

Cross Reference

Introduction

To understand associated biological information of baicalein, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with baicalein?

baicalein is suspected in Ischemia, Fibrillation, Hypertensive disease, Coronary Occlusion, Morphologically altered structure, Transient ischemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with baicalein

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Inflammation D007249 119 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Fatty Liver D005234 48 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with baicalein

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with baicalein?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with baicalein?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with baicalein?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with baicalein?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with baicalein?

Mouse Model

Mouse Model are used in the study 'Identification of a natural compound by cell-based screening that enhances interferon regulatory factor-1 activity and causes tumor suppression.' (Gao J et al., 2011) and Mouse Model are used in the study 'Baicalein and 12/15-lipoxygenase in the ischemic brain.' (van Leyen K et al., 2006).

Knock-out

Knock-out are used in the study 'Protecting against cerebrovascular injury: contributions of 12/15-lipoxygenase to edema formation after transient focal ischemia.' (Jin G et al., 2008).

Parkinsonism, Experimental

Parkinsonism, Experimental are used in the study 'Cu(II) promotes amyloid pore formation.' (Zhang H et al., 2015).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with baicalein

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Per page 10 20 50 100 | Total 1278
Authors Title Published Journal PubMed Link
Omwenga EO et al. Chitosan nanoencapsulation of flavonoids enhances their quorum sensing and biofilm formation inhibitory activities against an E.coli Top 10 biosensor. 2018 Colloids Surf B Biointerfaces pmid:29413589
Chen C et al. Baicalein protects renal tubular epithelial cells againsthypoxia-reoxygenation injury. 2018 Ren Fail pmid:30384801
Min W et al. Effect of Baicalein on GLUT4 Translocation in Adipocytes of Diet-Induced Obese Mice. 2018 Cell. Physiol. Biochem. pmid:30308480
Li Y et al. Drug interaction study of flavonoids toward CYP3A4 and their quantitative structure activity relationship (QSAR) analysis for predicting potential effects. 2018 Toxicol. Lett. pmid:29753067
Chassagne F et al. A metabolomic approach to identify anti-hepatocarcinogenic compounds from plants used traditionally in the treatment of liver diseases. 2018 Fitoterapia pmid:29477305
Shao Z et al. Baicalein Rescues Delayed Cooling via Preservation of Akt Activation and Akt-Mediated Phospholamban Phosphorylation. 2018 Int J Mol Sci pmid:29587364
Li J et al. Baicalein sensitizes hepatocellular carcinoma cells to 5-FU and Epirubicin by activating apoptosis and ameliorating P-glycoprotein activity. 2018 Biomed. Pharmacother. pmid:29571250
Wang X et al. Phosphorus doped graphitic carbon nitride nanosheets as fluorescence probe for the detection of baicalein. 2018 Spectrochim Acta A Mol Biomol Spectrosc pmid:29501001
Yu X et al. Baicalein induces cervical cancer apoptosis through the NF-κB signaling pathway. 2018 Mol Med Rep pmid:29393414
Li Y et al. Triggering of Autophagy by Baicalein in Response to Apoptosis after Spinal Cord Injury: Possible Involvement of the PI3K Activation. 2018 Biol. Pharm. Bull. pmid:29367475