| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Seizures | D012640 | 87 associated lipids |
| Carcinoma, Non-Small-Cell Lung | D002289 | 72 associated lipids |
Oroxylin A
Oroxylin A is a lipid of Polyketides (PK) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 747 references associated with Oroxylin A in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for Oroxylin A
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Oroxylin A
NCBI Entrez Crosslinks
All references with Oroxylin A
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Fong SY et al. | Development of a SPE-LC/MS/MS method for simultaneous quantification of baicalein, wogonin, oroxylin A and their glucuronides baicalin, wogonoside and oroxyloside in rats and its application to brain uptake and plasma pharmacokinetic studies. | 2014 | J Pharm Biomed Anal | pmid:24803030 |
| Fong SY and Zuo Z | Species difference in the inhibitory potentials of non-steroidal anti-inflammatory drugs on the hepatic sulfation and glucuronidation of bioactive flavonoids: differential observations among common inhibition parameters. | 2014 | Xenobiotica | pmid:24168065 |
| Kim DH et al. | Oroxylin A enhances memory consolidation through the brain-derived neurotrophic factor in mice. | 2014 | Brain Res. Bull. | pmid:25218897 |
| Hui H et al. | Oroxylin A inhibits ATRA-induced IL-6 expression involved in retinoic acid syndrome by down-regulating CHOP. | 2014 | Gene | pmid:25192658 |
| Cheng Y et al. | Oroxylin A inhibits hypoxia-induced invasion and migration of MCF-7 cells by suppressing the Notch pathway. | 2014 | Anticancer Drugs | pmid:24637576 |
| Ku SK et al. | Inhibitory effects of oroxylin A on endothelial protein C receptor shedding in vitro and in vivo. | 2014 | BMB Rep | pmid:24286327 |
| Zhu L et al. | Oroxylin A reverses P-glycoprotein-mediated multidrug resistance of MCF7/ADR cells by G2/M arrest. | 2013 | Toxicol. Lett. | pmid:23470866 |
| Wei L et al. | Oroxylin A sensitizes non-small cell lung cancer cells to anoikis via glucose-deprivation-like mechanisms: c-Src and hexokinase II. | 2013 | Biochim. Biophys. Acta | pmid:23500080 |
| Yang X et al. | Oroxylin A inhibits colitis-associated carcinogenesis through modulating the IL-6/STAT3 signaling pathway. | 2013 | Inflamm. Bowel Dis. | pmid:23823704 |
| Wei L et al. | Oroxylin A induces dissociation of hexokinase II from the mitochondria and inhibits glycolysis by SIRT3-mediated deacetylation of cyclophilin D in breast carcinoma. | 2013 | Cell Death Dis | pmid:23598413 |
| Dong J et al. | Oroxylin A inhibits hemolysis via hindering the self-assembly of α-hemolysin heptameric transmembrane pore. | 2013 | PLoS Comput. Biol. | pmid:23349625 |
| Yoon SY et al. | Oroxylin A improves attention deficit hyperactivity disorder-like behaviors in the spontaneously hypertensive rat and inhibits reuptake of dopamine in vitro. | 2013 | Arch. Pharm. Res. | pmid:23371806 |
| Liu X et al. | The ameliorating effects of 5,7-dihydroxy-6-methoxy-2(4-phenoxyphenyl)-4H-chromene-4-one, an oroxylin A derivative, against memory impairment and sensorimotor gating deficit in mice. | 2013 | Arch. Pharm. Res. | pmid:23543630 |
| dela Peña IC et al. | 5,7-Dihydroxy-6-methoxy-4'-phenoxyflavone, a derivative of oroxylin A improves attention-deficit/hyperactivity disorder (ADHD)-like behaviors in spontaneously hypertensive rats. | 2013 | Eur. J. Pharmacol. | pmid:23707903 |
| Wang H et al. | An estrogen receptor dependent mechanism of Oroxylin A in the repression of inflammatory response. | 2013 | PLoS ONE | pmid:23922737 |
| Zhu R et al. | Oroxylin A accelerates liver regeneration in CClâ‚„-induced acute liver injury mice. | 2013 | PLoS ONE | pmid:23951204 |
| Dai Q et al. | Two p53-related metabolic regulators, TIGAR and SCO2, contribute to oroxylin A-mediated glucose metabolism in human hepatoma HepG2 cells. | 2013 | Int. J. Biochem. Cell Biol. | pmid:23612020 |
| Qiu J et al. | Molecular modeling reveals the novel inhibition mechanism and binding mode of three natural compounds to staphylococcal α-hemolysin. | 2013 | PLoS ONE | pmid:24312202 |
| Kim DH et al. | 4'-bromo-5,6,7-trimethoxyflavone represses lipopolysaccharide-induced iNOS and COX-2 expressions by suppressing the NF-κB signaling pathway in RAW 264.7 macrophages. | 2012 | Bioorg. Med. Chem. Lett. | pmid:22101131 |
| Yang HY et al. | Oroxylin A reverses multi-drug resistance of human hepatoma BEL7402/5-FU cells via downregulation of P-glycoprotein expression by inhibiting NF-κB signaling pathway. | 2012 | Mol. Carcinog. | pmid:21557331 |
| Zou M et al. | Beclin 1-mediated autophagy in hepatocellular carcinoma cells: implication in anticancer efficiency of oroxylin A via inhibition of mTOR signaling. | 2012 | Cell. Signal. | pmid:22560876 |
| Hu R et al. | The role of Nrf2 and apoptotic signaling pathways in oroxylin A-mediated responses in HCT-116 colorectal adenocarcinoma cells and xenograft tumors. | 2012 | Anticancer Drugs | pmid:22526619 |
| Ha J et al. | Oroxylin A improves the sensitivity of HT-29 human colon cancer cells to 5-FU through modulation of the COX-2 signaling pathway. | 2012 | Biochem. Cell Biol. | pmid:22607196 |
| Xu M et al. | Activation of the unfolded protein response contributed to the selective cytotoxicity of oroxylin A in human hepatocellular carcinoma HepG2 cells. | 2012 | Toxicol. Lett. | pmid:22609744 |
| Lu Z et al. | Oroxylin A inhibits matrix metalloproteinase-2/9 expression and activation by up-regulating tissue inhibitor of metalloproteinase-2 and suppressing the ERK1/2 signaling pathway. | 2012 | Toxicol. Lett. | pmid:22245252 |
| Zhu B et al. | Oroxylin A reverses CAM-DR of HepG2 cells by suppressing Integrinβ1 and its related pathway. | 2012 | Toxicol. Appl. Pharmacol. | pmid:22310179 |
| Fu W et al. | Synthesis and biological evaluation of 7-O-modified oroxylin A derivatives. | 2012 | Bioorg. Med. Chem. Lett. | pmid:22196122 |
| Tong L et al. | Simultaneous determination of baicalin, wogonoside, baicalein, wogonin, oroxylin A and chrysin of Radix scutellariae extract in rat plasma by liquid chromatography tandem mass spectrometry. | 2012 | J Pharm Biomed Anal | pmid:22703838 |
| Pham TA et al. | Oroxylin A analogs exhibited strong inhibitory activities against iNOS-mediated nitric oxide (NO) production. | 2012 | Bioorg. Med. Chem. Lett. | pmid:22366656 |
| Wang H et al. | [Vasodilator effect of oroxylin A on thoracic aorta isolated from rats]. | 2012 | Zhong Xi Yi Jie He Xue Bao | pmid:22883404 |
| Song X et al. | Oroxylin A, a classical natural product, shows a novel inhibitory effect on angiogenesis induced by lipopolysaccharide. | 2012 | Pharmacol Rep | pmid:23238475 |
| Liu PW et al. | STAT1 mediates oroxylin a inhibition of iNOS and pro-inflammatory cytokines expression in microglial BV-2 cells. | 2012 | PLoS ONE | pmid:23236370 |
| Guo H et al. | [Preparation of flavonoid reference standards from Scutellariae Radix under the guidance of high performance liquid chromatography-mass spectrometry analysis]. | 2012 | Se Pu | pmid:23189664 |
| Tseng TL et al. | Oroxylin-A rescues LPS-induced acute lung injury via regulation of NF-κB signaling pathway in rodents. | 2012 | PLoS ONE | pmid:23071799 |
| Lu QY et al. | Detection of baicalin metabolites baicalein and oroxylin-a in mouse pancreas and pancreatic xenografts. | 2012 | Pancreas | pmid:22158070 |
| Li C et al. | Comparison of intestinal absorption and disposition of structurally similar bioactive flavones in Radix Scutellariae. | 2012 | AAPS J | pmid:22167378 |
| Jeon SJ et al. | Oroxylin A increases BDNF production by activation of MAPK-CREB pathway in rat primary cortical neuronal culture. | 2011 | Neurosci. Res. | pmid:21145362 |
| Li C et al. | Identification and quantification of baicalein, wogonin, oroxylin A and their major glucuronide conjugated metabolites in rat plasma after oral administration of Radix scutellariae product. | 2011 | J Pharm Biomed Anal | pmid:21051171 |
| Lee S et al. | Oroxylin A, a flavonoid, stimulates adult neurogenesis in the hippocampal dentate gyrus region of mice. | 2010 | Neurochem. Res. | pmid:20680459 |
| Zhao L et al. | Synergistic effect of 5-fluorouracil and the flavanoid oroxylin A on HepG2 human hepatocellular carcinoma and on H22 transplanted mice. | 2010 | Cancer Chemother. Pharmacol. | pmid:19585117 |
| Gao Y et al. | Oroxylin A inhibits angiogenesis through blocking vascular endothelial growth factor-induced KDR/Flk-1 phosphorylation. | 2010 | J. Cancer Res. Clin. Oncol. | pmid:19888602 |
| Zhou Q et al. | Use of isoform-specific UGT metabolism to determine and describe rates and profiles of glucuronidation of wogonin and oroxylin A by human liver and intestinal microsomes. | 2010 | Pharm. Res. | pmid:20411407 |
| Marques MR et al. | Flavonoids with prolyl oligopeptidase inhibitory activity isolated from Scutellaria racemosa Pers. | 2010 | Fitoterapia | pmid:20117183 |
| Kumar GS et al. | Synthesis and biological evaluation of novel benzyl-substituted flavones as free radical (DPPH) scavengers and α-glucosidase inhibitors. | 2010 | J Asian Nat Prod Res | pmid:21061220 |
| Trinh HT et al. | Anti-pruritic effect of baicalin and its metabolites, baicalein and oroxylin A, in mice. | 2010 | Acta Pharmacol. Sin. | pmid:20453872 |
| Li HN et al. | Apoptosis induction of oroxylin A in human cervical cancer HeLa cell line in vitro and in vivo. | 2009 | Toxicology | pmid:19135124 |
| Sun Y et al. | Oroxylin A suppresses invasion through down-regulating the expression of matrix metalloproteinase-2/9 in MDA-MB-435 human breast cancer cells. | 2009 | Eur. J. Pharmacol. | pmid:19100732 |
| Liu W et al. | MAC-related mitochondrial pathway in oroxylin-A-induced apoptosis in human hepatocellular carcinoma HepG2 cells. | 2009 | Cancer Lett. | pmid:19473757 |
| Mu R et al. | Involvement of p53 in oroxylin A-induced apoptosis in cancer cells. | 2009 | Mol. Carcinog. | pmid:19626645 |
| Zhou XQ et al. | [Flavonoids from Scutellaria baicalensis and their bioactivities]. | 2009 | Beijing Da Xue Xue Bao | pmid:19829679 |