Hispidulin

Hispidulin is a lipid of Polyketides (PK) class. Hispidulin is associated with abnormalities such as Chagas Disease and Leishmania mexicana disease. The involved functions are known as Metabolic Inhibition.

Cross Reference

Introduction

To understand associated biological information of Hispidulin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Hispidulin?

Hispidulin is suspected in Leishmania mexicana disease, Chagas Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Hispidulin

MeSH term MeSH ID Detail
Prostatic Neoplasms D011471 126 associated lipids
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Glioblastoma D005909 27 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with Hispidulin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Hispidulin?

There are no associated biomedical information in the current reference collection.

What functions are associated with Hispidulin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Hispidulin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Hispidulin?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Hispidulin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Hispidulin

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Authors Title Published Journal PubMed Link
pmid:
Bourdillat B et al. Hispidulin, a natural flavone, inhibits human platelet aggregation by increasing cAMP levels. 1988 Eur. J. Pharmacol. pmid:2836213
Abdalla S et al. Effects of hispidulin, a flavone isolated from Inula viscosa, on isolated guinea-pig smooth muscle. 1988 Gen. Pharmacol. pmid:3410278
Chulasiri M et al. Mutagenicity and antimutagenicity of hispidulin and hortensin, the flavonoids from Millingtonia hortensis L. 1992 Environ. Mol. Mutagen. pmid:1425610
Gil B et al. Effects of flavonoids on Naja naja and human recombinant synovial phospholipases A2 and inflammatory responses in mice. 1994 Life Sci. pmid:8190018
Shen XL et al. Inhibition of [methyl-3H]diazepam binding to rat brain membranes in vitro by dinatin and skrofulein. 1994 Zhongguo Yao Li Xue Bao pmid:7717057
Ferrándiz ML et al. Hispidulin protection against hepatotoxicity induced by bromobenzene in mice. 1994 Life Sci. pmid:8046988
Chulasiri M Mutagenicity and antimutagenicity of flavonoids extracted from Millingtonia hortensis L. 1998 J Toxicol Sci pmid:9760470
Valentão P et al. Analysis of vervain flavonoids by HPLC/Diode array detector method. Its application to quality control. 1999 J. Agric. Food Chem. pmid:10552853
Cui B et al. Cytotoxic sesquiterpenoids from Ratibida columnifera. 1999 J. Nat. Prod. pmid:10579870