| MeSH term | MeSH ID | Detail |
|---|---|---|
| Papillomavirus Infections | D030361 | 4 associated lipids |
| Penile Induration | D010411 | 4 associated lipids |
| Lymphoma, Large B-Cell, Diffuse | D016403 | 13 associated lipids |
| Carcinoma | D002277 | 18 associated lipids |
| Myocardial Reperfusion Injury | D015428 | 20 associated lipids |
| Translocation, Genetic | D014178 | 20 associated lipids |
| Sarcoma 180 | D012510 | 21 associated lipids |
| Breast Neoplasms | D001943 | 24 associated lipids |
| Gastritis | D005756 | 27 associated lipids |
| Neurodegenerative Diseases | D019636 | 32 associated lipids |
Wogonin
Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.
Cross Reference
Introduction
To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Wogonin?
Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Wogonin
PubChem Associated disorders and diseases
What pathways are associated with Wogonin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Wogonin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Wogonin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Wogonin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Wogonin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Wogonin?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Wogonin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Piao HZ et al. | Wogonin inhibits microglial cell migration via suppression of nuclear factor-kappa B activity. | 2008 | Int. Immunopharmacol. | pmid:18725324 |
| BÅ‚ach-Olszewska Z et al. | Production of cytokines and stimulation of resistance to viral infection in human leukocytes by Scutellaria baicalensis flavones. | 2008 | J. Interferon Cytokine Res. | pmid:18771341 |
| Kallifatidis G et al. | Sulforaphane targets pancreatic tumour-initiating cells by NF-kappaB-induced antiapoptotic signalling. | 2009 | Gut | pmid:18829980 |
| Qi Q et al. | Toxicological studies of wogonin in experimental animals. | 2009 | Phytother Res | pmid:19003942 |
| Li-Weber M | New therapeutic aspects of flavones: the anticancer properties of Scutellaria and its main active constituents Wogonin, Baicalein and Baicalin. | 2009 | Cancer Treat. Rev. | pmid:19004559 |
| Parajuli P et al. | In vitro antitumor mechanisms of various Scutellaria extracts and constituent flavonoids. | 2009 | Planta Med. | pmid:19031366 |
| Wohlfarth C and Efferth T | Natural products as promising drug candidates for the treatment of hepatitis B and C. | 2009 | Acta Pharmacol. Sin. | pmid:19060918 |
| Si D et al. | Mechanism of CYP2C9 inhibition by flavones and flavonols. | 2009 | Drug Metab. Dispos. | pmid:19074529 |
| Xu L et al. | Multiple compounds determination and fingerprint analysis of Lidanpaishi tablet and keli by high-performance liquid chromatography. | 2009 | Anal. Chim. Acta | pmid:19110127 |
| Feng Y et al. | Bear bile: dilemma of traditional medicinal use and animal protection. | 2009 | J Ethnobiol Ethnomed | pmid:19138420 |
| Tran TD et al. | Inhibitory activity of prostaglandin E2 production by the synthetic 2'-hydroxychalcone analogues: Synthesis and SAR study. | 2009 | Bioorg. Med. Chem. Lett. | pmid:19233646 |
| Yin L et al. | Simultaneous determination of 11 active components in two well-known traditional Chinese medicines by HPLC coupled with diode array detection for quality control. | 2009 | J Pharm Biomed Anal | pmid:19264437 |
| Parekh HS et al. | A new dawn for the use of traditional Chinese medicine in cancer therapy. | 2009 | Mol. Cancer | pmid:19298677 |
| Shih YT et al. | San-Huang-Xie-Xin-Tang Protects against Activated Microglia- and 6-OHDA-Induced Toxicity in Neuronal SH-SY5Y Cells. | 2011 | Evid Based Complement Alternat Med | pmid:19339484 |
| Chen FP et al. | Prescriptions of Chinese Herbal Medicines for Insomnia in Taiwan during 2002. | 2011 | Evid Based Complement Alternat Med | pmid:19339485 |
| Peng J et al. | Subchronic toxicity and plasma pharmacokinetic studies on wogonin, a natural flavonoid, in Beagle dogs. | 2009 | J Ethnopharmacol | pmid:19397969 |
| Lee DH et al. | Reactive oxygen species up-regulate p53 and Puma; a possible mechanism for apoptosis during combined treatment with TRAIL and wogonin. | 2009 | Br. J. Pharmacol. | pmid:19438509 |
| Li C et al. | Contents of major bioactive flavones in proprietary traditional Chinese medicine products and reference herb of radix Scutellariae. | 2009 | J Pharm Biomed Anal | pmid:19481403 |
| Lu B et al. | Simple and reliable methods for the determination of sixteen marker components for quality control of Daochi pill by HPLC coupled with diode array detection. | 2009 Sep-Oct | Phytochem Anal | pmid:19533595 |
| Li J et al. | Scuteflorins A and B, dihydropyranocoumarins from Scutellaria lateriflora. | 2009 | J. Nat. Prod. | pmid:19555121 |
| Kaneko T et al. | Effect of Scutellariae radix ingredients on prostaglandin E(2) production and COX-2 expression by LPS-activated macrophage. | 2009 Jul-Aug | In Vivo | pmid:19567393 |
| Ozmen A et al. | In vitro anti-leukemic activity of the ethno-pharmacological plant Scutellaria orientalis ssp. carica endemic to western Turkey. | 2010 | Phytomedicine | pmid:19576743 |
| Huang ST et al. | Wogonin, an active compound in Scutellaria baicalensis, induces apoptosis and reduces telomerase activity in the HL-60 leukemia cells. | 2010 | Phytomedicine | pmid:19577445 |
| Cao H et al. | Arsenic accumulation in Scutellaria baicalensis Georgi and its effects on plant growth and pharmaceutical components. | 2009 | J. Hazard. Mater. | pmid:19577841 |
| Chen CM et al. | Maternal baicalin treatment increases fetal lung surfactant phospholipids in rats. | 2011 | Evid Based Complement Alternat Med | pmid:19584080 |
| Ding XF et al. | [Analysis of the 4th generation Scutellaria baicalensis Georgi with space mutagenesis via FTIR spectroscopy]. | 2009 | Guang Pu Xue Yu Guang Pu Fen Xi | pmid:19650472 |
| Rushworth SA and Micheau O | Molecular crosstalk between TRAIL and natural antioxidants in the treatment of cancer. | 2009 | Br. J. Pharmacol. | pmid:19664138 |
| Calvo TR et al. | Mutagenic Activity of Indigofera truxillensis and I. suffruticosa Aerial Parts. | 2011 | Evid Based Complement Alternat Med | pmid:19696193 |
| Lee E et al. | Inhibition of P-glycoprotein by wogonin is involved with the potentiation of etoposide-induced apoptosis in cancer cells. | 2009 | Ann. N. Y. Acad. Sci. | pmid:19723047 |
| Shia CS et al. | Metabolism and pharmacokinetics of san-huang-xie-xin-tang, a polyphenol-rich chinese medicine formula, in rats and ex-vivo antioxidant activity. | 2011 | Evid Based Complement Alternat Med | pmid:19737807 |
| Liang X et al. | Qualitative and quantitative analysis of traditional Chinese medicine Niu Huang Jie Du Pill using ultra performance liquid chromatography coupled with tunable UV detector and rapid resolution liquid chromatography coupled with time-of-flight tandem mass spectrometry. | 2010 | J Pharm Biomed Anal | pmid:19783115 |
| Willimott S et al. | An in vitro based investigation of the cytotoxic effect of water extracts of the Chinese herbal remedy LD on cancer cells. | 2009 | Chem Cent J | pmid:19785738 |
| Zhou XQ et al. | [Flavonoids from Scutellaria baicalensis and their bioactivities]. | 2009 | Beijing Da Xue Xue Bao | pmid:19829679 |
| Wang CZ et al. | Selective fraction of Scutellaria baicalensis and its chemopreventive effects on MCF-7 human breast cancer cells. | 2010 | Phytomedicine | pmid:19836937 |
| Ishii K et al. | Effects of naturally occurring polymethyoxyflavonoids on cell growth, p-glycoprotein function, cell cycle, and apoptosis of daunorubicin-resistant T lymphoblastoid leukemia cells. | 2010 | Cancer Invest. | pmid:19863351 |
| Yang L et al. | Wogonin induces G1 phase arrest through inhibiting Cdk4 and cyclin D1 concomitant with an elevation in p21Cip1 in human cervical carcinoma HeLa cells. | 2009 | Biochem. Cell Biol. | pmid:19935879 |
| Jang S et al. | Wogonin inhibits osteoclast formation induced by lipopolysaccharide. | 2010 | Phytother Res | pmid:19998398 |
| Chen B et al. | Synergistic effect of magnetic nanoparticles of Fe(3)O(4) with gambogic acid on apoptosis of K562 leukemia cells. | 2009 | Int J Nanomedicine | pmid:20011242 |
| Tayarani-Najaran Z et al. | Analyzing Cytotoxic and Apoptogenic Properties of Scutellaria litwinowii Root Extract on Cancer Cell Lines. | 2011 | Evid Based Complement Alternat Med | pmid:20028719 |
| Kim HS et al. | Cloning and expression of beta-glucuronidase from Lactobacillus brevis in E. coli and application in the bioconversion of baicalin and wogonoside. | 2009 | J. Microbiol. Biotechnol. | pmid:20075633 |
| Gurung SK et al. | Inhibition of prostaglandin E2 production by synthetic wogonin analogs. | 2009 | Arch. Pharm. Res. | pmid:20091262 |
| Kaneko T et al. | Inhibition of prostaglandin E2 production by flavone and its related compounds. | In Vivo | pmid:20133976 | |
| You J et al. | On-line continuous flow ultrasonic extraction coupled with high performance liquid chromatographic separation for determination of the flavonoids from root of Scutellaria baicalensis Georgi. | 2010 | J Chromatogr A | pmid:20138285 |
| Li Y et al. | Combinative method using HPLC fingerprint and quantitative analyses for quality consistency evaluation of an herbal medicinal preparation produced by different manufacturers. | 2010 | J Pharm Biomed Anal | pmid:20138726 |
| Ni Y et al. | Spectrometric study of the interaction between alpinetin and bovine serum albumin using chemometrics approaches. | 2010 | Anal. Chim. Acta | pmid:20206002 |
| Ijaz AZ et al. | MKEM: a Multi-level Knowledge Emergence Model for mining undiscovered public knowledge. | 2010 | BMC Bioinformatics | pmid:20406501 |
| Zhou Q et al. | Use of isoform-specific UGT metabolism to determine and describe rates and profiles of glucuronidation of wogonin and oroxylin A by human liver and intestinal microsomes. | 2010 | Pharm. Res. | pmid:20411407 |
| Kong EK et al. | Baicalein and Wogonin inhibit collagen deposition in SHR and WKY cardiac fibroblast cultures. | 2010 | BMB Rep | pmid:20423617 |
| Feng J et al. | Simultaneous determination of baicalin, baicalein, wogonin, berberine, palmatine and jatrorrhizine in rat plasma by liquid chromatography-tandem mass spectrometry and application in pharmacokinetic studies after oral administration of traditional Chinese medicinal preparations containing scutellaria-coptis herb couple. | 2010 | J Pharm Biomed Anal | pmid:20430560 |
| Cui X et al. | Traditional Chinese medicine and related active compounds against hepatitis B virus infection. | 2010 | Biosci Trends | pmid:20448340 |