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A specialized flavone biosynthetic pathway has evolved in the medicinal plant, Scutellaria baicalensis. |
2016 |
Sci Adv |
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2016 |
Molecules |
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Fibroblast growth factor (Fgf) 23 gene transcription depends on actin cytoskeleton reorganization. |
2016 |
FEBS Lett. |
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Protective effects of Huangqin Decoction against ulcerative colitis and associated cancer in mice. |
2016 |
Oncotarget |
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Kim EH et al. |
Targeting Nrf2 with wogonin overcomes cisplatin resistance in head and neck cancer. |
2016 |
Apoptosis |
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Endotoxin-induced acute lung injury in mice is protected by 5,7-dihydroxy-8-methoxyflavone via inhibition of oxidative stress and HIF-1α. |
2016 |
Environ. Toxicol. |
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Apoptotic Mechanism of Human Leukemia K562/A02 Cells Induced by Magnetic Ferroferric Oxide Nanoparticles Loaded with Wogonin. |
2016 |
Chin. Med. J. |
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Characterization and Bioavailability of Wogonin by Different Administration Routes in Beagles. |
2016 |
Med. Sci. Monit. |
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A Novel Prostate-Specific Membrane-Antigen (PSMA) Targeted Micelle-Encapsulating Wogonin Inhibits Prostate Cancer Cell Proliferation via Inducing Intrinsic Apoptotic Pathway. |
2016 |
Int J Mol Sci |
pmid:27196894
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Wogonin inhibits multiple myeloma-stimulated angiogenesis via c-Myc/VHL/HIF-1α signaling axis. |
2016 |
Oncotarget |
pmid:26735336
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BM microenvironmental protection of CML cells from imatinib through Stat5/NF-κB signaling and reversal by Wogonin. |
2016 |
Oncotarget |
pmid:27027438
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Wogonin attenuates diabetic cardiomyopathy through its anti-inflammatory and anti-oxidative properties. |
2016 |
Mol. Cell. Endocrinol. |
pmid:27013352
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Acute lung injury induced by lipopolysaccharide is inhibited by wogonin in mice via reduction of Akt phosphorylation and RhoA activation. |
2016 |
J. Pharm. Pharmacol. |
pmid:26749510
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Cryptotanshinone and wogonin up-regulate eNOS in vascular endothelial cells via ERα and down-regulate iNOS in LPS stimulated vascular smooth muscle cells via ERβ. |
2016 |
Arch. Pharm. Res. |
pmid:26481132
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Zhao L et al. |
LW-213 induces G2/M cell cycle arrest through AKT/GSK3β/β-catenin signaling pathway in human breast cancer cells. |
2016 |
Mol. Carcinog. |
pmid:25945460
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Tu B et al. |
Structure-activity relationship study between baicalein and wogonin by spectrometry, molecular docking and microcalorimetry. |
2016 |
Food Chem |
pmid:27132840
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Seo CS and Shin HK |
HPLC-PDA Method for Simultaneous Determination of Nine Marker Components in Banhasasim-Tang. |
2016 |
J Chromatogr Sci |
pmid:26354947
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Ku SK et al. |
Inhibitory effect of baicalin, baicalein and wogonin on secretory group IIA phospholipase A2. |
2015 |
Arch. Pharm. Res. |
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Antiradical and antioxidant activity of flavones from Scutellariae baicalensis radix. |
2015 |
Nat. Prod. Res. |
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Anti-inflammatory effects of Baicalin, Baicalein, and Wogonin in vitro and in vivo. |
2015 |
Inflammation |
pmid:25249339
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Deep Sequencing of the Scutellaria baicalensis Georgi Transcriptome Reveals Flavonoid Biosynthetic Profiling and Organ-Specific Gene Expression. |
2015 |
PLoS ONE |
pmid:26317778
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Ku SK and Bae JS |
Baicalin, baicalein and wogonin inhibits high glucose-induced vascular inflammation in vitro and in vivo. |
2015 |
BMB Rep |
pmid:25739393
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In vitro effects of some flavones on human pyruvate kinase isoenzyme M2. |
2015 |
J. Biochem. Mol. Toxicol. |
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Vasodilatory Effect of Wogonin on the Rat Aorta and Its Mechanism Study. |
2015 |
Biol. Pharm. Bull. |
pmid:26632179
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Lu H et al. |
Wogonin inhibits the proliferation of myelodysplastic syndrome cells through the induction of cell cycle arrest and apoptosis. |
2015 |
Mol Med Rep |
pmid:26398525
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Zhang YM et al. |
Wogonin suppresses osteopontin expression in adipocytes by activating PPARα. |
2015 |
Acta Pharmacol. Sin. |
pmid:26073326
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Lee JY and Park W |
Anti-Inflammatory Effect of Wogonin on RAW 264.7 Mouse Macrophages Induced with Polyinosinic-Polycytidylic Acid. |
2015 |
Molecules |
pmid:25913928
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Wogonin induces eosinophil apoptosis and attenuates allergic airway inflammation. |
2015 |
Am. J. Respir. Crit. Care Med. |
pmid:25629436
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Targeting CDK9 by wogonin and related natural flavones potentiates the anti-cancer efficacy of the Bcl-2 family inhibitor ABT-263. |
2015 |
Int. J. Cancer |
pmid:24895203
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Wogonin Inhibits Tumor-derived Regulatory Molecules by Suppressing STAT3 Signaling to Promote Tumor Immunity. |
2015 |
J. Immunother. |
pmid:25962106
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Huang Y et al. |
Wogonin inhibits LPS-induced vascular permeability via suppressing MLCK/MLC pathway. |
2015 |
Vascul. Pharmacol. |
pmid:25956732
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Wang W et al. |
Wogonin suppresses inflammatory response and maintains intestinal barrier function via TLR4-MyD88-TAK1-mediated NF-κB pathway in vitro. |
2015 |
Inflamm. Res. |
pmid:25917044
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Wogonin induces apoptosis and endoplasmic reticulum stress in HL-60 leukemia cells through inhibition of the PI3K-AKT signaling pathway. |
2015 |
Oncol. Rep. |
pmid:25846394
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Drug-induced death of eosinophils. Promises and pitfalls. |
2015 |
Am. J. Respir. Crit. Care Med. |
pmid:25767918
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Ge W et al. |
Wogonin Induced Mitochondrial Dysfunction and Endoplasmic Reticulum Stress in Human Malignant Neuroblastoma Cells Via IRE1α-Dependent Pathway. |
2015 |
J. Mol. Neurosci. |
pmid:25740014
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Tan CX et al. |
Activities of wogonin analogs and other flavones against Flavobacterium columnare. |
2015 |
Chem. Biodivers. |
pmid:25676507
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Zhu Y and Wang J |
Wogonin increases β-amyloid clearance and inhibits tau phosphorylation via inhibition of mammalian target of rapamycin: potential drug to treat Alzheimer's disease. |
2015 |
Neurol. Sci. |
pmid:25596147
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Growth inhibition and apoptosis induction by Scutellaria pinnatifida A. Ham. on HL-60 and K562 leukemic cell lines. |
2015 |
Environ. Toxicol. Pharmacol. |
pmid:25546119
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Chen S et al. |
Wogonin inhibits LPS-induced inflammatory responses in rat dorsal root ganglion neurons via inhibiting TLR4-MyD88-TAK1-mediated NF-κB and MAPK signaling pathway. |
2015 |
Cell. Mol. Neurobiol. |
pmid:25504431
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Chen F et al. |
Wogonin protects rat dorsal root ganglion neurons against tunicamycin-induced ER stress through the PERK-eIF2α-ATF4 signaling pathway. |
2015 |
J. Mol. Neurosci. |
pmid:25417142
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Xu S et al. |
Wogonin prevents rat dorsal root ganglion neurons death via inhibiting tunicamycin-induced ER stress in vitro. |
2015 |
Cell. Mol. Neurobiol. |
pmid:25381475
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Zhao Y et al. |
Wogonin suppresses human alveolar adenocarcinoma cell A549 migration in inflammatory microenvironment by modulating the IL-6/STAT3 signaling pathway. |
2015 |
Mol. Carcinog. |
pmid:24976450
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Song X et al. |
Wogonin influences vascular permeability via Wnt/β-catenin pathway. |
2015 |
Mol. Carcinog. |
pmid:24136474
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Yeh CH et al. |
Protective effect of wogonin on proinflammatory cytokine generation via Jak1/3-STAT1/3 pathway in lipopolysaccharide stimulated BV2 microglial cells. |
2015 |
Toxicol Ind Health |
pmid:23592745
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Xiao JR et al. |
Potential therapeutic effects of baicalein, baicalin, and wogonin in ocular disorders. |
2014 |
J Ocul Pharmacol Ther |
pmid:25280175
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Sikder MA et al. |
Inhibition of TNF-α-induced MUC5AC mucin gene expression and production by wogonin through the inactivation of NF-κB signaling in airway epithelial cells. |
2014 |
Phytother Res |
pmid:23463646
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Yan T et al. |
Wogonin modulates hydroperoxide-induced apoptosis via PI3K/Akt pathway in retinal pigment epithelium cells. |
2014 |
Diagn Pathol |
pmid:25432585
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Zhao K et al. |
Wogonin suppresses melanoma cell B16-F10 invasion and migration by inhibiting Ras-medicated pathways. |
2014 |
PLoS ONE |
pmid:25203554
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Yang H et al. |
Wogonin induces cell cycle arrest and erythroid differentiation in imatinib-resistant K562 cells and primary CML cells. |
2014 |
Oncotarget |
pmid:25149543
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Xu X et al. |
Wogonin reverses multi-drug resistance of human myelogenous leukemia K562/A02 cells via downregulation of MRP1 expression by inhibiting Nrf2/ARE signaling pathway. |
2014 |
Biochem. Pharmacol. |
pmid:25264278
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