Messaoudene D et al. |
Ex vivo effects of flavonoïds extracted from Artemisia herba alba on cytokines and nitric oxide production in Algerian patients with Adamantiades-Behçet's disease. |
2011 |
J Inflamm (Lond) |
pmid:22104639
|
Ma SC et al. |
Antiviral Chinese medicinal herbs against respiratory syncytial virus. |
2002 |
J Ethnopharmacol |
pmid:11801383
|
Sonoda M et al. |
Cytotoxic activities of flavonoids from two Scutellaria plants in Chinese medicine. |
2004 |
J Ethnopharmacol |
pmid:15036470
|
Lim BO |
Effects of wogonin, wogonoside, and 3,5,7,2',6'-pentahydroxyflavone on chemical mediator production in peritoneal exduate cells and immunoglobulin E of rat mesenteric lymph node lymphocytes. |
2003 |
J Ethnopharmacol |
pmid:12499072
|
Zeng H et al. |
The inhibitory activities of the components of Huang-Lian-Jie-Du-Tang (HLJDT) on eicosanoid generation via lipoxygenase pathway. |
2011 |
J Ethnopharmacol |
pmid:21466840
|
Peng J et al. |
Subchronic toxicity and plasma pharmacokinetic studies on wogonin, a natural flavonoid, in Beagle dogs. |
2009 |
J Ethnopharmacol |
pmid:19397969
|
Ho FM et al. |
Anti-atherosclerotic action of Ger-Gen-Chyn-Lian-Tang and AMPK-dependent lipid lowering effect in hepatocytes. |
2012 |
J Ethnopharmacol |
pmid:22543166
|
Dong P et al. |
Wogonin, an active ingredient of Chinese herb medicine Scutellaria baicalensis, inhibits the mobility and invasion of human gallbladder carcinoma GBC-SD cells by inducing the expression of maspin. |
2011 |
J Ethnopharmacol |
pmid:21855619
|
Feng Y et al. |
Bear bile: dilemma of traditional medicinal use and animal protection. |
2009 |
J Ethnobiol Ethnomed |
pmid:19138420
|
Kunwar RM et al. |
Traditional herbal medicine in far-west Nepal: a pharmacological appraisal. |
2010 |
J Ethnobiol Ethnomed |
pmid:21144003
|
Ohta Y et al. |
Saikokeishito Extract Exerts a Therapeutic Effect on alpha-Naphthylisothiocyanate-Induced Liver Injury in Rats through Attenuation of Enhanced Neutrophil Infiltration and Oxidative Stress in the Liver Tissue. |
2007 |
J Clin Biochem Nutr |
pmid:18437211
|
Seo CS and Shin HK |
HPLC-PDA Method for Simultaneous Determination of Nine Marker Components in Banhasasim-Tang. |
2016 |
J Chromatogr Sci |
pmid:26354947
|
Lin SJ et al. |
Determination of gentiopicroside, mangiferin, palmatine, berberine, baicalin, wogonin and glycyrrhizin in the traditional Chinese medicinal preparation sann-joong-kuey-jian-tang by high-performance liquid chromatography. |
1996 |
J Chromatogr A |
pmid:8680588
|
Li HB and Chen F |
Isolation and purification of baicalein, wogonin and oroxylin A from the medicinal plant Scutellaria baicalensis by high-speed counter-current chromatography. |
2005 |
J Chromatogr A |
pmid:15941045
|
Zhang H et al. |
Analysis of baicalein, baicalin and wogonin in Scutellariae radix and its preparation by microemulsion electrokinetic chromatography with 1-butyl-3-methylimizolium tetrafluoborate ionic liquid as additive. |
2006 |
J Chromatogr A |
pmid:16952364
|
Zgórka G |
Retention behavior of silica-bonded and novel polymeric reversed-phase sorbents in studies on flavones as chemotaxonomic markers of Scutellaria L. genus. |
2006 |
J Chromatogr A |
pmid:16364344
|
You J et al. |
On-line continuous flow ultrasonic extraction coupled with high performance liquid chromatographic separation for determination of the flavonoids from root of Scutellaria baicalensis Georgi. |
2010 |
J Chromatogr A |
pmid:20138285
|
Wang CZ et al. |
Deglycosylation of wogonoside enhances its anticancer potential. |
2018 |
J Cancer Res Ther |
pmid:30249874
|
Wang CZ et al. |
Hydrophobic flavonoids from Scutellaria baicalensis induce colorectal cancer cell apoptosis through a mitochondrial-mediated pathway. |
2013 |
Int. J. Oncol. |
pmid:23337959
|
Gong WY et al. |
Flavonoid components in Scutellaria baicalensis inhibit nicotine-induced proliferation, metastasis and lung cancer-associated inflammation in vitro. |
2014 |
Int. J. Oncol. |
pmid:24604573
|
Chen S et al. |
Down-regulation of androgen-receptor and PSA by phytochemicals. |
2008 |
Int. J. Oncol. |
pmid:18202763
|
Lin CC et al. |
Wogonin triggers apoptosis in human osteosarcoma U-2 OS cells through the endoplasmic reticulum stress, mitochondrial dysfunction and caspase-3-dependent signaling pathways. |
2011 |
Int. J. Oncol. |
pmid:21573491
|
Go JH et al. |
Wogonin suppresses the LPS‑enhanced invasiveness of MDA‑MB‑231 breast cancer cells by inhibiting the 5‑LO/BLT2 cascade. |
2018 |
Int. J. Mol. Med. |
pmid:30015917
|
Liu X et al. |
Wogonin inhibits the proliferation and invasion, and induces the apoptosis of HepG2 and Bel7402 HCC cells through NF‑κB/Bcl-2, EGFR and EGFR downstream ERK/AKT signaling. |
2016 |
Int. J. Mol. Med. |
pmid:27499272
|
Wang HW et al. |
Reversal of inflammation-associated dihydrodiol dehydrogenases (AKR1C1 and AKR1C2) overexpression and drug resistance in nonsmall cell lung cancer cells by wogonin and chrysin. |
2007 |
Int. J. Cancer |
pmid:17266043
|
Polier G et al. |
Targeting CDK9 by wogonin and related natural flavones potentiates the anti-cancer efficacy of the Bcl-2 family inhibitor ABT-263. |
2015 |
Int. J. Cancer |
pmid:24895203
|
Chung H et al. |
Anticancer effects of wogonin in both estrogen receptor-positive and -negative human breast cancer cell lines in vitro and in nude mice xenografts. |
2008 |
Int. J. Cancer |
pmid:17957784
|
Lee HW et al. |
Potent inhibition of monoamine oxidase A by decursin from Angelica gigas Nakai and by wogonin from Scutellaria baicalensis Georgi. |
2017 |
Int. J. Biol. Macromol. |
pmid:28109809
|
Liu Y et al. |
Binding of wogonin to human gammaglobulin. |
2005 |
Int. J. Biol. Macromol. |
pmid:16242767
|
Lin CM et al. |
Protective role of wogonin against lipopolysaccharide-induced angiogenesis via VEGFR-2, not VEGFR-1. |
2006 |
Int. Immunopharmacol. |
pmid:16979123
|
Piao HZ et al. |
Wogonin inhibits microglial cell migration via suppression of nuclear factor-kappa B activity. |
2008 |
Int. Immunopharmacol. |
pmid:18725324
|
Kapoor S |
Protective effects of wogonin against disease progression in different hepatic pathological conditions. |
2017 |
Int. Immunopharmacol. |
pmid:28886583
|
Li HD et al. |
Wogonin attenuates inflammation by activating PPAR-γ in alcoholic liver disease. |
2017 |
Int. Immunopharmacol. |
pmid:28646664
|
Huang KF et al. |
Wogonin induces apoptosis and down-regulates survivin in human breast cancer MCF-7 cells by modulating PI3K-AKT pathway. |
2012 |
Int. Immunopharmacol. |
pmid:22182776
|
Huang GC et al. |
Wogonin but not Nor-wogonin inhibits lipopolysaccharide and lipoteichoic acid-induced iNOS gene expression and NO production in macrophages. |
2007 |
Int. Immunopharmacol. |
pmid:17570322
|
Yu H et al. |
Enhancement of solubility and dissolution rate of baicalein, wogonin and oroxylin A extracted from Radix scutellariae. |
2017 |
Int J Pharm |
pmid:28642200
|
Chen B et al. |
Synergistic effect of magnetic nanoparticles of Fe(3)O(4) with gambogic acid on apoptosis of K562 leukemia cells. |
2009 |
Int J Nanomedicine |
pmid:20011242
|
Cheng J et al. |
Effect of magnetic nanoparticles of Fe3O4 and wogonin on the reversal of multidrug resistance in K562/A02 cell line. |
2012 |
Int J Nanomedicine |
pmid:22745547
|
Wang L et al. |
Effect of magnetic nanoparticles on apoptosis and cell cycle induced by wogonin in Raji cells. |
2012 |
Int J Nanomedicine |
pmid:22359456
|
Hung CW et al. |
Stem cell-based neuroprotective and neurorestorative strategies. |
2010 |
Int J Mol Sci |
pmid:20559500
|
Khoo BY et al. |
Apoptotic effects of chrysin in human cancer cell lines. |
2010 |
Int J Mol Sci |
pmid:20559509
|
Mazzio EA et al. |
The biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's disease. |
2011 |
Int J Mol Sci |
pmid:21340000
|
Tsai CF et al. |
Wogonin induces reactive oxygen species production and cell apoptosis in human glioma cancer cells. |
2012 |
Int J Mol Sci |
pmid:22949836
|
Zhang H et al. |
A Novel Prostate-Specific Membrane-Antigen (PSMA) Targeted Micelle-Encapsulating Wogonin Inhibits Prostate Cancer Cell Proliferation via Inducing Intrinsic Apoptotic Pathway. |
2016 |
Int J Mol Sci |
pmid:27196894
|
Lee W et al. |
Anti-inflammatory effects of Baicalin, Baicalein, and Wogonin in vitro and in vivo. |
2015 |
Inflammation |
pmid:25249339
|
Wang W et al. |
Wogonin suppresses inflammatory response and maintains intestinal barrier function via TLR4-MyD88-TAK1-mediated NF-κB pathway in vitro. |
2015 |
Inflamm. Res. |
pmid:25917044
|
Lin CC et al. |
Wogonin, a natural and biologically-active flavonoid, influences a murine WEHI-3 leukemia model in vivo through enhancing populations of T- and B-cells. |
2013 Nov-Dec |
In Vivo |
pmid:24292576
|
Kaneko T et al. |
Effect of Scutellariae radix ingredients on prostaglandin E(2) production and COX-2 expression by LPS-activated macrophage. |
2009 Jul-Aug |
In Vivo |
pmid:19567393
|
Tang NY et al. |
Effects of wogonin on the levels of cytokines and functions of leukocytes associated with NF-kappa B expression in Sprague-Dawley rats. |
2006 Jul-Aug |
In Vivo |
pmid:16900784
|
Kaneko T et al. |
Inhibition of prostaglandin E2 production by flavone and its related compounds. |
|
In Vivo |
pmid:20133976
|
Yao J et al. |
Wogonin prevents lipopolysaccharide-induced acute lung injury and inflammation in mice via peroxisome proliferator-activated receptor gamma-mediated attenuation of the nuclear factor-kappaB pathway. |
2014 |
Immunology |
pmid:24766487
|
Yu JQ et al. |
Changes in mitochondrial membrane potential and reactive oxygen species during wogonin-induced cell death in human hepatoma cells. |
2007 |
Hepatol. Res. |
pmid:17300700
|
Kallifatidis G et al. |
Sulforaphane targets pancreatic tumour-initiating cells by NF-kappaB-induced antiapoptotic signalling. |
2009 |
Gut |
pmid:18829980
|
Ding XF et al. |
[Analysis of the 4th generation Scutellaria baicalensis Georgi with space mutagenesis via FTIR spectroscopy]. |
2009 |
Guang Pu Xue Yu Guang Pu Fen Xi |
pmid:19650472
|
Lei W et al. |
Molecular cloning and expression profiling of a chalcone synthase gene from hairy root cultures of Scutellaria viscidula Bunge. |
2010 |
Genet. Mol. Biol. |
pmid:21637484
|
Zhao K et al. |
LW-215, a newly synthesized flavonoid, exhibits potent anti-angiogenic activity in vitro and in vivo. |
2018 |
Gene |
pmid:29196258
|
Park NI et al. |
Enhancement of flavone levels through overexpression of chalcone isomerase in hairy root cultures of Scutellaria baicalensis. |
2011 |
Funct. Integr. Genomics |
pmid:21538138
|
Matsunaga T et al. |
Aldo-Keto Reductase 1B10 and Its Role in Proliferation Capacity of Drug-Resistant Cancers. |
2012 |
Front Pharmacol |
pmid:22319498
|
Qian C et al. |
Wogonin-enhanced reactive oxygen species-induced apoptosis and potentiated cytotoxic effects of chemotherapeutic agents by suppression Nrf2-mediated signaling in HepG2 cells. |
2014 |
Free Radic. Res. |
pmid:24666416
|
Khan NM et al. |
Wogonin, a plant derived small molecule, exerts potent anti-inflammatory and chondroprotective effects through the activation of ROS/ERK/Nrf2 signaling pathways in human Osteoarthritis chondrocytes. |
2017 |
Free Radic. Biol. Med. |
pmid:28237856
|
Attia SM et al. |
Wogonin attenuates etoposide-induced oxidative DNA damage and apoptosis via suppression of oxidative DNA stress and modulation of OGG1 expression. |
2013 |
Food Chem. Toxicol. |
pmid:23872129
|
Dong LL et al. |
An enhanced preparation and purification of the major antioxidants baicalein and wogonin from Scutellariae radix. |
2012 |
Food Chem |
pmid:25683416
|
Tu B et al. |
Structure-activity relationship study between baicalein and wogonin by spectrometry, molecular docking and microcalorimetry. |
2016 |
Food Chem |
pmid:27132840
|
Liu J et al. |
Screening of osteoanagenesis-active compounds from Scutellaria baicalensis Georgi by hPDLC/CMC-online-HPLC/MS. |
2014 |
Fitoterapia |
pmid:24393619
|
Tian SS et al. |
Flavonoids from the leaves of Carya cathayensis Sarg. inhibit vascular endothelial growth factor-induced angiogenesis. |
2014 |
Fitoterapia |
pmid:24096161
|
Ku SK and Bae JS |
Antithrombotic activities of wogonin and wogonoside via inhibiting platelet aggregation. |
2014 |
Fitoterapia |
pmid:25020199
|
Fajol A et al. |
Fibroblast growth factor (Fgf) 23 gene transcription depends on actin cytoskeleton reorganization. |
2016 |
FEBS Lett. |
pmid:26878191
|
Lee H et al. |
Flavonoid wogonin from medicinal herb is neuroprotective by inhibiting inflammatory activation of microglia. |
2003 |
FASEB J. |
pmid:12897065
|
Nakamura N et al. |
Effects of baicalin, baicalein, and wogonin on interleukin-6 and interleukin-8 expression, and nuclear factor-kappab binding activities induced by interleukin-1beta in human retinal pigment epithelial cell line. |
2003 |
Exp. Eye Res. |
pmid:12873450
|
Li Y and Martin RC |
Herbal medicine and hepatocellular carcinoma: applications and challenges. |
2011 |
Evid Based Complement Alternat Med |
pmid:21799681
|
Shia CS et al. |
Metabolism and pharmacokinetics of san-huang-xie-xin-tang, a polyphenol-rich chinese medicine formula, in rats and ex-vivo antioxidant activity. |
2011 |
Evid Based Complement Alternat Med |
pmid:19737807
|
Chen CM et al. |
Maternal baicalin treatment increases fetal lung surfactant phospholipids in rats. |
2011 |
Evid Based Complement Alternat Med |
pmid:19584080
|
Shih YT et al. |
San-Huang-Xie-Xin-Tang Protects against Activated Microglia- and 6-OHDA-Induced Toxicity in Neuronal SH-SY5Y Cells. |
2011 |
Evid Based Complement Alternat Med |
pmid:19339484
|
Adams LS et al. |
Analysis of the interactions of botanical extract combinations against the viability of prostate cancer cell lines. |
2006 |
Evid Based Complement Alternat Med |
pmid:16550232
|
Li X et al. |
Effect of an Ethanol Extract of Scutellaria baicalensis on Relaxation in Corpus Cavernosum Smooth Muscle. |
2012 |
Evid Based Complement Alternat Med |
pmid:22235229
|
Wang TC et al. |
Yang-Dan-Tang, Identified from 15 Chinese Herbal Formulae, Inhibits Human Lung Cancer Cell Proliferation via Cell Cycle Arrest. |
2012 |
Evid Based Complement Alternat Med |
pmid:22693529
|
Qi XF et al. |
Bambusae caulis in Liquamen Suppresses the Expression of Thymus and Activation-Regulated Chemokine and Macrophage-Derived Chemokine in Human Keratinocytes due to Antioxidant Effect. |
2012 |
Evid Based Complement Alternat Med |
pmid:21785648
|
Chen FP et al. |
Prescriptions of Chinese Herbal Medicines for Insomnia in Taiwan during 2002. |
2011 |
Evid Based Complement Alternat Med |
pmid:19339485
|
Tayarani-Najaran Z et al. |
Analyzing Cytotoxic and Apoptogenic Properties of Scutellaria litwinowii Root Extract on Cancer Cell Lines. |
2011 |
Evid Based Complement Alternat Med |
pmid:20028719
|
Calvo TR et al. |
Mutagenic Activity of Indigofera truxillensis and I. suffruticosa Aerial Parts. |
2011 |
Evid Based Complement Alternat Med |
pmid:19696193
|
Im AR et al. |
Scutellaria baicalensis Extracts and Flavonoids Protect Rat L6 Cells from Antimycin A-Induced Mitochondrial Dysfunction. |
2012 |
Evid Based Complement Alternat Med |
pmid:22969827
|
Pan SY et al. |
New perspectives on chinese herbal medicine (zhong-yao) research and development. |
2011 |
Evid Based Complement Alternat Med |
pmid:21785622
|
Lo YC et al. |
Neuroprotective Effects of San-Huang-Xie-Xin-Tang in the MPP(+)/MPTP Models of Parkinson's Disease In Vitro and In Vivo. |
2012 |
Evid Based Complement Alternat Med |
pmid:22474505
|
Zhang N et al. |
A Herbal Composition of Scutellaria baicalensis and Eleutherococcus senticosus Shows Potent Anti-Inflammatory Effects in an Ex Vivo Human Mucosal Tissue Model. |
2012 |
Evid Based Complement Alternat Med |
pmid:22272213
|
Zhang HW et al. |
Wogonin induced differentiation and G1 phase arrest of human U-937 leukemia cells via PKCdelta phosphorylation. |
2008 |
Eur. J. Pharmacol. |
pmid:18577379
|
Chang WT et al. |
Comparative effects of flavonoids on oxidant scavenging and ischemia-reperfusion injury in cardiomyocytes. |
2007 |
Eur. J. Pharmacol. |
pmid:17475241
|
Park BK et al. |
Inhibition of TPA-induced cyclooxygenase-2 expression and skin inflammation in mice by wogonin, a plant flavone from Scutellaria radix. |
2001 |
Eur. J. Pharmacol. |
pmid:11502282
|
Toton E et al. |
The tetramethoxyflavone zapotin selectively activates protein kinase C epsilon, leading to its down-modulation accompanied by Bcl-2, c-Jun and c-Fos decrease. |
2012 |
Eur. J. Pharmacol. |
pmid:22381066
|
Shen SC et al. |
In vitro and in vivo inhibitory activities of rutin, wogonin, and quercetin on lipopolysaccharide-induced nitric oxide and prostaglandin E(2) production. |
2002 |
Eur. J. Pharmacol. |
pmid:12098601
|
Wakabayashi I and Yasui K |
Wogonin inhibits inducible prostaglandin E(2) production in macrophages. |
2000 |
Eur. J. Pharmacol. |
pmid:11040356
|
Son D et al. |
Neuroprotective effect of wogonin in hippocampal slice culture exposed to oxygen and glucose deprivation. |
2004 |
Eur. J. Pharmacol. |
pmid:15189769
|
Kimura Y and Sumiyoshi M |
Effects of baicalein and wogonin isolated from Scutellaria baicalensis roots on skin damage in acute UVB-irradiated hairless mice. |
2011 |
Eur. J. Pharmacol. |
pmid:21549115
|
Cho J and Lee HK |
Wogonin inhibits excitotoxic and oxidative neuronal damage in primary cultured rat cortical cells. |
2004 |
Eur. J. Pharmacol. |
pmid:14757129
|
Zhao Y et al. |
Effects of flavonoids extracted from Scutellaria baicalensis Georgi on hemin-nitrite-H2O2 induced liver injury. |
2006 |
Eur. J. Pharmacol. |
pmid:16574098
|
Huang HC et al. |
Antiproliferative effect of baicalein, a flavonoid from a Chinese herb, on vascular smooth muscle cell. |
1994 |
Eur. J. Pharmacol. |
pmid:8137874
|
Ohtake N et al. |
The herbal medicine Sho-saiko-to selectively inhibits CD8+ T-cell proliferation. |
2005 |
Eur. J. Pharmacol. |
pmid:15659321
|
Zhao K et al. |
Wogonin inhibits LPS-induced tumor angiogenesis via suppressing PI3K/Akt/NF-κB signaling. |
2014 |
Eur. J. Pharmacol. |
pmid:24858369
|
Park HG et al. |
Anticonvulsant effect of wogonin isolated from Scutellaria baicalensis. |
2007 |
Eur. J. Pharmacol. |
pmid:17692312
|
Park HJ et al. |
Induction of quinone reductase by a methanol extract of Scutellaria baicalensis and its flavonoids in murine Hepa 1c1c7 cells. |
1998 |
Eur. J. Cancer Prev. |
pmid:9926295
|
Ono K et al. |
Differential inhibitory effects of various flavonoids on the activities of reverse transcriptase and cellular DNA and RNA polymerases. |
1990 |
Eur. J. Biochem. |
pmid:1695572
|